International Journal of Trichology最新文献

{"title":"Acquired Progressive Kinking of Hair in a 13-year-old Adolescent.","authors":"Dominga Peirano Deck, Miquela Martínez Magallón, Marianne Kolbach Rengifo","doi":"10.4103/ijt.ijt_128_23","DOIUrl":"10.4103/ijt.ijt_128_23","url":null,"abstract":"<p><strong>Introduction: </strong>Acquired progressive kinking of the hair (APKH) is a rare condition in which the hair of the scalp changes in appearance. This disorder has been described infrequently over the years, so it is believed that it is being diagnosed late by physicians. We present a case of a patient with APKH.</p><p><strong>Case: </strong>A 13-year-old woman consulted for 8 months of evolution of changes on the appearance of her hair, being darker, thicker, and more brittle than usual. The physical examination reveals the presence of thick short hair and isolated long dark hair in the coronal area. Trichoscopy showed periodic reductions on the diameter of the hair shaft and no areas of alopecia suggestive of APKH.</p><p><strong>Discussion: </strong>APKH is an extremely rare condition in which hair of the scalp changes in appearance. It is very important to know the physical changes produced on the hair to avoid misdiagnosis. We report the case to make this pathology more widely known among professionals and encourage the reporting of this unusual disorder.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"64-65"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Focused Repetitive Behavior at an Unusual Site and in an Unusual Pattern - Symmetrical Trichotillomania.","authors":"Shrishti Singh, Aayush Gupta, Rohan Manoj","doi":"10.4103/ijt.ijt_95_23","DOIUrl":"10.4103/ijt.ijt_95_23","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"97-98"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trichoscopic Evolution of Alopecia Areata: An Algorithmic Approach.","authors":"Tarang Goyal, Vineet Relhan","doi":"10.4103/ijt.ijt_104_23","DOIUrl":"10.4103/ijt.ijt_104_23","url":null,"abstract":"<p><p>With the introduction of Trichoscopy as a rapid, non-invasive diagnostic tool the need for histopathological evaluation has been reduced except for a few indications. There are a constellation of findings seen in alopecia areata which differ with types, severity and nature of the disease. We have tried to develop an algorithm towards the evolution of signs seen in this disease which may help the clinicians as well as researchers in establishing the diagnosis, disease severity, progression and monitoring the therapy response. Also, the trichoscopic progression of these findings as per the lesion and its severity is explained with an algorithmic approach. Few variants like Alopecia areata incognita which are still a matter of debate have also been included as per the trichoscopic evaluation.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"84-89"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrichia Congenita with Papular Lesions: A Report of Rare Case Showing \"Cluster of Stars' Appearance on Dermoscopy\".","authors":"Hayyal Shobha Sarojadevi, Veena Ullas Nair, Chandramohan Kudligi, Meghana Patil, Jayashree Basavaraju, Navya Kalappurakkal Gopinathan","doi":"10.4103/ijt.ijt_36_22","DOIUrl":"10.4103/ijt.ijt_36_22","url":null,"abstract":"<p><p>Atrichia congenita with papular lesions (APL) is a rare autosomal recessive form of alopecia with multiple keratin cysts. A 12-year-old boy with generalized alopecia who was unsuccessfully treated with multiple topical and systemic medications was brought to our department. Thorough history, examination and investigations confirmed the diagnosis of APL as the patient fulfilled the proposed criteria required to diagnose the condition. He also had a distinct previously observed dermoscopic clue \"Cluster of Stars\" appearance. The present case is reported to familiarize the clinician about this rare entity which not only helps in making proper diagnosis but also avoid unnecessary treatment as it mimics many similar conditions such as alopecia universalis, Vitamin D dependent rickets, and ectodermal dysplasia.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"80-83"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Role of the Gabrin Sign in Predicting COVID-19 Severity Among Patients with Androgenic Alopecia.","authors":"Alpana Mohta, Sumiti Pareek, Asha Nyati, Vijeta Prasad, Manoj Kumar Sharma, Bhikam Chand Ghiya","doi":"10.4103/ijt.ijt_5_23","DOIUrl":"10.4103/ijt.ijt_5_23","url":null,"abstract":"<p><strong>Introduction: </strong>The \"Gabrin sign\" has been named after Dr Frank Gabrin, who was the first American physician to succumb to the novel coronavirus disease 2019 (COVID-19). The physician also suffered from androgenetic alopecia (AGA), thence came the eponymous sign. It has been widely postulated that the androgen pathway is a contributing factor in COVID-19 disease severity.</p><p><strong>Aims and objectives: </strong>This case-control study was aimed at assessing the prevalence of AGA in patients admitted to the intensive care unit due to severe COVID-19 from three tertiary care centers in Rajasthan.</p><p><strong>Materials and methods: </strong>During the overwhelming surge of cases between March 2021 and August 2021, the investigators randomly examined patients for the presence of AGA. AGA severity was assessed by the Hamilton-Norwood Scale and Ludwig Scale.</p><p><strong>Results: </strong>The study included 379 cases of AGA with confirmed COVID-19 infection admitted in COVID-19 dedicated wards and 379 age- and sex-matched controls without AGA from the same wards. The male-to-female ratio was 3.9:1. The disease severity of COVID-19 was significantly higher in cases than controls (<i>P</i> < 0.0001). Cases with severe AGA had a significantly higher proportion of COVID-19 severity (<i>P</i> < 0.0001).</p><p><strong>Conclusions: </strong>Our study provides preliminary evidence that COVID-19 severity could be androgen-mediated. However, this hypothesis requires further validation. In addition, antiandrogen treatments such as spironolactone, degarelix, and bicalutamide could theoretically be investigated in the management or prophylaxis of COVID-19 severity.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"54-57"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Waardenburg Syndrome in a Family.","authors":"M Niveditha, Priya Prathap, Neelakandhan Asokan","doi":"10.4103/ijt.ijt_134_22","DOIUrl":"10.4103/ijt.ijt_134_22","url":null,"abstract":"<p><p>Waardenburg syndrome (WS) is an autosomal dominant genetic disease with an estimated prevalence of 1 in 20,000-40,000. An 8-year-old boy, born to nonconsanguineous parents, presented with complaints of areas of depigmentation on the forehead and right leg since birth. On examination, there was a well-defined amelanotic macule on the center of the forehead of size 5 cm × 2.5 cm with a few spots of normal pigmentation, a forelock of white hair on the frontal area of the scalp, and a well-defined amelanotic macule of size 6 cm × 4 cm with a small central area of normal pigmentation on the posterior part of the right leg. He had scoliosis of the spine in the thoracic region. The nasal root was broad with widely separated inner canthi. There was exotropia and microcornea of the right eye with a visual acuity of 6/24. Fundus examination of the right eye showed a large disc, disc coloboma, peripapillary atrophy, and pigmentary changes in the fovea. The left eye was normal. There was no hearing defect. His father and two siblings too had patchy amelanosis in a similar distribution. They probably represent a limited expression of the same disease. All of them meet the diagnostic criteria for WS. WS is rare with only <100 cases reported worldwide.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"73-76"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Loose Anagen Hair Syndrome in an Indian Child with Trichoscopic Features.","authors":"Isha Gupta, Aanchal Bansal, Surabhi Dayal, Chinmay Ku Mandal","doi":"10.4103/ijt.ijt_147_22","DOIUrl":"10.4103/ijt.ijt_147_22","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"101-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Randomized Controlled Trial Study to Evaluate the Efficacy of Combination Therapy with Diphenylcyclopropenone and Platelet-Rich Plasmain Alopecia Areaata.","authors":"Robabeh Abedini, Azadeh Rezayat, Narges Ghandi, Aida Varghaei, Mojtaba Sedaghat, Hamidreza Mahmoudi","doi":"10.4103/ijt.ijt_37_22","DOIUrl":"10.4103/ijt.ijt_37_22","url":null,"abstract":"<p><strong>Introduction: </strong>Diphenylcyclopropenone (DPCP) is an effective treatment in severe alopecia areata (AA). Platelet-rich plasma (PRP) has been introduced as an effective modality in AA. We present the first study to evaluate and compare the efficacy and tolerability of DPCP alone and DPCP in combination with PRP in the treatment of severe AA.</p><p><strong>Methods: </strong>This is a comparative, randomized, double-blind study that included 14 patients with severe AA. Participants received weekly DPCP plus monthly PRP to treat alopecia patches on one side of their scalp (group 1) and DPCP plus placebo on the other side (group 2). Patient's response was evaluated with the severity of alopecia tool (SALT) score and trichoscopy scores. PRP was injected for 3 times and patients were followed for 6 months.</p><p><strong>Results: </strong>Among enrolled patients, 7 (50%) experienced a hair regrowth >50%. The mean SALT score and trichoscopy scaled scores decreased over time for both the groups. Nevertheless, there were no significant differences between groups. The side effect was not noticeable in either group.</p><p><strong>Conclusions: </strong>This is the first study to investigate a synergistic effect with DPCP and PRP. According to this study, PRP is ineffective as an adjunct to DPCP for augmenting its effectiveness.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topical Alternatives for Hair Loss: Beyond the Conventional.","authors":"Chingshubam Bikash","doi":"10.4103/ijt.ijt_8_23","DOIUrl":"10.4103/ijt.ijt_8_23","url":null,"abstract":"<p><p>Topical hair growth supplements in the form of hair growth serums, oils, and shampoos have flooded the cosmeceutical market. The gullible masses are targeted with sponsored marketing gimmicks through social media platforms. This review article brings to light the most hyped active ingredients or peptides in these products along with their clinical evidence available in the literature. The topical actives include Redensyl, Procapil, Capixyl, Baicapil, AnaGain, onion juice, coffee extract, saw palmetto extract, pumpkin seed oil (PSO), and rosemary oil. PubMed, Google Scholar, and Google databases were searched with the keywords: topical, hair growth, hair loss, and the respective active agents. Twenty-four relevant articles and technical files were extracted and reviewed. They have been studied mostly as combined formulations with other agents in randomized controlled trials or prospective cohort studies and have shown promising results. However, most of the studies have limited sample size, lack of comparison with standard therapies, nonuniformity between study groups, nondisclosure of the type of alopecia treated, and conflicts of interest. These topicals with their less significant side effect profile may find their use as an add-on therapy or as an alternative in patients not tolerating standard therapies. In this fast-growing commercialized world, it is imperative that we remain vigilant and understand the pros and cons of these products and ultimately guide our patients to the right track.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"13-19"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trichopathology of Cicatricial Alopecia.","authors":"Preksha Singh, Taru Garg, Shilpi Agarwal, Amit Kumar Meena, Ram Chander, Deeksha Singh","doi":"10.4103/ijt.ijt_123_23","DOIUrl":"10.4103/ijt.ijt_123_23","url":null,"abstract":"<p><strong>Background: </strong>Patchy/focal alopecia can be noncicatricial or cicatricial. Trichopathology may play an important role in confirming and/or establishing the diagnosis of cicatricial alopecia.</p><p><strong>Aims: </strong>The aim of this study was to study the trichopathologic features of common cicatricial conditions presenting with patchy scalp alopecia.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted over a period of 1 year in the department of dermatology and pathology in a tertiary care hospital in North India. Adult patients (age >18 years) presenting with patchy cicatricial alopecia as well as clinically doubtful noncicatricial conditions over the scalp were included in this study. In doubtful cases of noncicatricial alopecia, a single 4-mm punch biopsy was performed for transverse sectioning with hematoxylin and eosin stain. In all cases of cicatricial alopecia, two 4-mm punch biopsies were performed, one for transverse sectioning and the second for vertical sectioning and direct immunofluorescence (DIF). The final diagnosis was made on the basis of the trichopathologic findings.</p><p><strong>Results: </strong>A total of 23 cases were included in our study with the majority (52.2%) being in the age group of 20-30 years. The mean age at diagnosis was 30.5 ± 11.38 years. On the basis of trichopathologic findings, a final diagnosis was made in 18 (78.3%) cases. However, 5 (21.7%) cases remained undiagnosed and were labeled as nonspecific. According to the final diagnosis based on the trichopathologic findings, maximum cases were of discoid lupus erythematosus (DLE) (26.1%), followed by lichen planopilaris (21.7%), pseudopelade of Brocq (13%), alopecia areata (8.7%), folliculitis decalvans (4.3%), and traction alopecia (4.3%). Trichopathologic examination revealed hyperkeratosis (60%), basal cell vacuolization (55%), epidermal atrophy (55%,) perifollicular lymphocytic infiltrate (30%), pigment incontinence (30%), perifollicular fibrosis (25%), and thickened basement membrane (25%). Only four cases showed deposits of immunoreactants in DIF and all four were finally diagnosed as DLE.</p><p><strong>Conclusions: </strong>Trichopathology along with special stain is a useful tool in the diagnosis of patchy alopecia and must be carried out in cases where diagnosis is in doubt clinically, particularly in cases of cicatricial alopecia. DIF may have a supportive role in histopathologically inconclusive cases and should be carried out, particularly when DLE is suspected. Trichopathology in combination with DIF is an important tool in the diagnosis of the majority of cases of cicatricial as well as clinically doubtful cases of noncicatricial alopecia.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"58-63"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}