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International Journal of Trichology最新文献

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Expansion of Human Dermal Papilla Cells for Clinical Applications Using Human Platelet-rich Plasma as a Substitute for Fetal Bovine Serum. 用人富血小板血浆替代胎牛血清扩增人真皮乳头细胞用于临床应用。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_100_22
Koji Kanayama, Harunosuke Kato, Kahori Kinoshita
{"title":"Expansion of Human Dermal Papilla Cells for Clinical Applications Using Human Platelet-rich Plasma as a Substitute for Fetal Bovine Serum.","authors":"Koji Kanayama, Harunosuke Kato, Kahori Kinoshita","doi":"10.4103/ijt.ijt_100_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_100_22","url":null,"abstract":"<p><strong>Context: </strong>Cell expansion for clinical cell culture often involves the use of fetal bovine serum (FBS). Recently, human platelet-rich plasma (hPRP) was suggested as an FBS substitute, to minimize the risk of transmission of various pathogens and immunogenic reactions. However, whether hPRP can replace FBS for the expansion of human dermal papilla cells (hDPCs) remains controversial.</p><p><strong>Aims: </strong>To assess the potential of hPRP as a substitute for FBS in hDPC expansion, we investigated the effect of hPRP on hDPC expansion.</p><p><strong>Materials and methods: </strong>We first standardized the method of hPRP preparation, and then investigated the effect of hPRP on the proliferation and hair-inductive capacity of cultured hDPCs by comparing with that of FBS. To prepare hPRP, we used heparin as the anticoagulant, with purification by single-spin centrifugation, and freeze-thaw hPRP activation.</p><p><strong>Results: </strong>Compared with an FBS-supplemented medium, hPRP supplementation significantly shortened the population doubling time of cultured hDPCs, and increased the ratio of bromodeoxyuridine-labeled proliferating cells. Expression of the alkaline phosphatase gene related to hair-inductive capacity was enhanced in hDPCs cultured in an hPRP-supplemented medium. <i>In vivo</i> hair follicle reconstitution assay confirmed that hPRP supplementation enhanced the hair-inductive capacity of hDPCs compared with an FBS-supplemented medium, based on the increased number of regenerated hair follicles and their maturity. Overall, compared with FBS, hPRP enhanced the proliferation of hDPCs, while preserving their hair-inductive capacity.</p><p><strong>Conclusions: </strong>The results show that hPRP can be used to replace FBS for hDPC expansion. These findings inform the development of an effective clinically applicable hair regeneration therapy.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"31-38"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Paroxonase 1 Level and Androgenetic Alopecia: Correspondence. 血清Paroxonase 1水平与雄激素性脱发：对应关系。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_112_21
Pathum Sookaromdee, Viroj Wiwanitkit
{"title":"Serum Paroxonase 1 Level and Androgenetic Alopecia: Correspondence.","authors":"Pathum Sookaromdee, Viroj Wiwanitkit","doi":"10.4103/ijt.ijt_112_21","DOIUrl":"https://doi.org/10.4103/ijt.ijt_112_21","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"62"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alopecic Scalp Cysts Following Isotretinoin. 异维甲酸引起的脱发性头皮囊肿。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_35_22
Agnes Lim, Wei-Liang Koh, Yong-Kwang Tay
{"title":"Alopecic Scalp Cysts Following Isotretinoin.","authors":"Agnes Lim, Wei-Liang Koh, Yong-Kwang Tay","doi":"10.4103/ijt.ijt_35_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_35_22","url":null,"abstract":"<p><p>Isotretinoin is often used for acne treatment. Common side effects include dry eyes and mouth, muscle aches, and hypertriglyceridemia. Scalp cysts have not yet been reported in conjunction with isotretinoin. In this report, we describe a case of alopecic scalp cysts developing following 3 weeks of isotretinoin use by a young female for facial nodulocystic acne. On dermoscopy, hair follicular openings were patent, with few scattered black dots and open comedones. A diagnosis of pseudo-acne fulminans was made, and she was treated with a tapering course of oral prednisolone, oral erythromycin, and topical minoxidil, with the resolution of the cysts and good hair regrowth. As isotretinoin is commonly used by dermatologists, it is important for clinicians to be aware of the presentation and treatment of this unintended outcome, particularly in acne patients with scalp comedones.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"50-51"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comment on Coronavirus Disease 2019 and the Hair. 2019冠状病毒病与头发评论
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_179_20
Hudson Dutra Rezende, Maria Fernanda Reis Gavazzoni Dias, Antonia Régnier, Natalia Caballero Uribe, Ralph Michel Trüeb
{"title":"A Comment on Coronavirus Disease 2019 and the Hair.","authors":"Hudson Dutra Rezende, Maria Fernanda Reis Gavazzoni Dias, Antonia Régnier, Natalia Caballero Uribe, Ralph Michel Trüeb","doi":"10.4103/ijt.ijt_179_20","DOIUrl":"https://doi.org/10.4103/ijt.ijt_179_20","url":null,"abstract":"<p><p>The novel viral pandemic coronavirus disease 2019 (COVID-19) has sparked uncertainties and controversies as to its origin, epidemiology, and natural course. In this situation, the medical disciplines strive to contribute to a better understanding of the disease with the best available evidence gained from the scientific method of observation and statistics. The study of the cutaneous manifestations of COVID-19 has evolved with the hope that they may be useful as markers for the disease, for prognostication, and further insights into the pathogenesis of the disease manifestations. With regard to the hair, clinicopathological correlations have remained hypothetic. Association of androgenetic alopecia (AGA) and gray hair with COVID-19 severity, COVID-19-associated postinfectious effluvium, scalp allodynia, and stress-induced telogen effluvium have been the objects of speculation. Further in-depth studies are warranted to establish whether COVID-19-associated hair loss is due to the systemic inflammation with fever, or whether the inflammation and/or severe acute respiratory syndrome coronavirus 2 may target the hair follicle. Meanwhile, dermatologic conditions have been investigated as cutaneous markers for elevated mortality risk, including AGA and graying. Ultimately, most have been scrutinized with regard to the accuracy and validity of the statistics and not been found to be convincing in identifying them as independent risk factors. We therefore challenge the proposal of the \"Gabrin sign\" as an eponym for AGA as a severity risk factor in COVID-19. Moreover, Dr. Frank Gabrin is rather to be remembered for his selfless and courageous service at the front lines of the pandemic than for the stigma of his alopecia.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Don't Judge When the Tresses Fall. 不要评头论足。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_38_21
B S Chandrashekhar, Chaithra Shenoy, T Anu George
{"title":"Don't Judge When the Tresses Fall.","authors":"B S Chandrashekhar, Chaithra Shenoy, T Anu George","doi":"10.4103/ijt.ijt_38_21","DOIUrl":"https://doi.org/10.4103/ijt.ijt_38_21","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"69-70"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of Force Exerted During Pull Test. 拉力试验中施加的力的测定。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_82_22
S Nithya, C R Srinivas, C K Nair Shashidharan
{"title":"Determination of Force Exerted During Pull Test.","authors":"S Nithya, C R Srinivas, C K Nair Shashidharan","doi":"10.4103/ijt.ijt_82_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_82_22","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this was to determine the force exerted during the pull test using a hand-held spring balance.</p><p><strong>Materials and methods: </strong>A hand-held spring balance was used to determine the force exerted during pull test. Ten volunteers performed the test five times each, and the mean was recorded as the force exerted by each volunteer.</p><p><strong>Results: </strong>A total of 10 volunteers were included in the study. The mean value of the force exerted by the volunteers was 0.25 N (Newton).</p><p><strong>Conclusion: </strong>Using the spring balance, we attempted to measure the force used while performing the pull test, which may help in standardizing the hair pull test. Further experiments are being undertaken to determine the grasping force exerted during pull test. These two forces when combined in an instrument will enable us to overcome the individual investigator variability while performing the test.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"13-15"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traction Folliculitis: An Unrecognized Entity. 牵引性毛囊炎：一个未被识别的实体。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_81_21
Damini Arora, Pooja Arora, Purnima Paliwal, Sunayana Misra
{"title":"Traction Folliculitis: An Unrecognized Entity.","authors":"Damini Arora, Pooja Arora, Purnima Paliwal, Sunayana Misra","doi":"10.4103/ijt.ijt_81_21","DOIUrl":"https://doi.org/10.4103/ijt.ijt_81_21","url":null,"abstract":"<p><p>Traction folliculitis (TF) is an uncommon and under-reported entity that presents as perifollicular erythema and pustules in patients in whom excessive traction is used while styling the hair. In this article, we report 2 patients who presented with TF subsequent to excessive traction while tying the hair. In both these patients, the condition improved with change of hairstyle.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"39-41"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Remission with Combination of Diphenylcyclopropenone and Apremilast in Refractory Extensive Alopecia Areata. 二苯环丙烯联合阿普米司特治疗难治性广泛性斑秃成功缓解。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_68_22
Siddhi B Chikhalkar, Savera Gupta, Snehal Umesh Chopade, Sushanti Jadhav, Vidya Kharkar
{"title":"Successful Remission with Combination of Diphenylcyclopropenone and Apremilast in Refractory Extensive Alopecia Areata.","authors":"Siddhi B Chikhalkar, Savera Gupta, Snehal Umesh Chopade, Sushanti Jadhav, Vidya Kharkar","doi":"10.4103/ijt.ijt_68_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_68_22","url":null,"abstract":"<p><p>Extensive alopecia areata including alopecia totalis and alopecia universalis is a therapeutic challenge in majority of the cases due to poor response to therapy, frequent relapses, minimal chances of spontaneous remission, and the associated psychological distress. Topical immunotherapy with diphenylcyclopropenone (DPCP) is one of the established therapeutic modalities for alopecia areata, although with a variable response rate. The use of systemic corticosteroids and other immunosuppressive drugs such as cyclosporine, azathioprine, and methotrexate is limited by their side effects. Apremilast, a phosphodiesterase-4 inhibitor, marked with a high safety profile and minimal monitoring, has been used off-label in many dermatological conditions including alopecia areata. We report three cases of extensive refractory alopecia areata with successful remission following combination therapy of DPCP and apremilast.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"47-49"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Apocrine Hidrocystoma: A Rare Benign Cystic Skin Tumor at Uncommon Site. 大汗腺汗腺瘤：一种罕见部位的良性囊性皮肤肿瘤。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_76_20
Sushma Bharti, Jyotsna Naresh Bharti, R Madhubala, Prabin Kumar
{"title":"Apocrine Hidrocystoma: A Rare Benign Cystic Skin Tumor at Uncommon Site.","authors":"Sushma Bharti, Jyotsna Naresh Bharti, R Madhubala, Prabin Kumar","doi":"10.4103/ijt.ijt_76_20","DOIUrl":"https://doi.org/10.4103/ijt.ijt_76_20","url":null,"abstract":"<p><p>Apocrine hidrocystoma (AH) is an uncommon benign cystic tumor, which arises from the apocrine secretory coil. The lesion is usually single and commonly seen over the face or scalp. It rarely involves the genitalia and if ever seen, then it occurs in foreskin followed by the shaft of the penis. AH commonly affects adults with equal gender incidence. Histopathological confirmation is done by the presence of cystic spaces in the dermis lined by bilaminar epithelium, outer myoepithelial cells and inner columnar, and eosinophilic cells with basally positioned nuclei, and often prominent apical snouts are also noted. It should be differentiated from other cystic lesions over the penile shaft. The treatment of choice is the complete excision. To date, only 13 cases of genital AH have been reported. Among that, very few cases have been reported over the penile shaft. Herein, we emphasize the importance of considering the differential diagnosis of the cystic lesion over the penile shaft.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"52-54"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical Glycosaminoglycan Lotion and Microneedling Therapy for Androgenetic Alopecia. 外用糖胺聚糖洗剂和微针治疗雄激素性脱发。
International Journal of Trichology Pub Date : 2024-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ijt.ijt_66_22
O M Moreno-Arrones, P Fernandez-Gonzalez, P Jaen, S Vañó-Galván
{"title":"Topical Glycosaminoglycan Lotion and Microneedling Therapy for Androgenetic Alopecia.","authors":"O M Moreno-Arrones, P Fernandez-Gonzalez, P Jaen, S Vañó-Galván","doi":"10.4103/ijt.ijt_66_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_66_22","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"65-66"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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