International Journal of Trichology最新文献

{"title":"Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.","authors":"Namrata Chhabra, C Anju George, Satyaki Ganguly","doi":"10.4103/ijt.ijt_38_22","DOIUrl":"10.4103/ijt.ijt_38_22","url":null,"abstract":"<p><strong>Background: </strong>Telogen effluvium (TE) is self limiting diffuse hair loss occurring 3-4 months after a triggering event. There is scarcity of data on TE as possible sequelae of COVID-19.</p><p><strong>Methods: </strong>We assessed 113 cases of TE occurring after SARS-CoV-2 infection as a retrospective study.</p><p><strong>Results: </strong>Most of the patients belonged to the age group 18-30 years and were females (85.8%). Most of the patients (92%) had acute TE. The median duration of hair loss was 2 months. Trichodynia and pruritus were the common associated complaints. Hair pull test was positive in 54.9% patients. Trichoscopy showed short regrowing hairs in 61.2% patients and empty hair follicles in 77.9% patients. Ferritin, vitamin D and Vitamin B12 deficiency was seen in 27.4%, 38.1% and 20.4% patients respectively. TE was seen more commonly with symptomatic COVID infection (93% patients).</p><p><strong>Conclusion: </strong>TE occurring after SARS-CoV-2 infection calls for assessment of micronutrient deficiency, as there appears to be an association between COVID-19 infection and nutritional deficiency. Although acute TE is the most common presentation, relapse in chronic TE might also occur as sequelae of COVID-19 infection.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"32-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Correlation of Alopecia Areata and Metabolic Syndrome in Northwest Indian Population: A Case-Control Study.","authors":"Mahmood Dhahir Al-Mendalawi","doi":"10.4103/ijt.ijt_84_23","DOIUrl":"10.4103/ijt.ijt_84_23","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"96"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Efficacy and Safety of Topical Spironolactone versus Topical Minoxidil in the Treatment of Female Pattern Hair Loss: A Comparative, Clinical, and Trichoscopic Study.","authors":"Ghada Fawzy Rezk Hassan, Rasha Elsayed Elsaftawy, Omar Yassin Mady, Shereen Farouk Gheida","doi":"10.4103/ijt.ijt_118_23","DOIUrl":"10.4103/ijt.ijt_118_23","url":null,"abstract":"<p><strong>Background: </strong>Female pattern hair loss (FPHL) is the most common hair loss disorder in women. Its origin is polygenic and multifactorial. Specific genetic factors predispose androgen receptors to be particularly sensitized so that they bind to circulating androgens, even with normal circulating levels.</p><p><strong>Objectives: </strong>The aim of this work was to evaluate and compare the efficacy and safety of topical spironolactone versus topical minoxidil in the treatment of FPHL.</p><p><strong>Methods: </strong>This prospective, simple randomized, comparative study was conducted on 80 female patients with FPHL. They were divided into two groups: Group (A): was subjected to topical spironolactone 1% gel application for 6 months, twice. Group (B): was subjected to topical minoxidil 5% gel application for 6 months, twice daily. The efficacy of treatment was assessed clinically by the Ludwig scale, Global Esthetic Improvement Scale, and trichoscopy.</p><p><strong>Results: </strong>There was a statistically significant difference in improvement in both groups after treatment as regards: the Ludwig scale, Global Esthetic Improvement Scale, and Trichoscopy. In Group A: 10 patients had mild, 16 patients had moderate, two patients had excellent, and 12 had marked improvement. In Group B: 10 patients had mild, 14 patients had moderate, two patients had excellent, and 14 had marked improvement. Contact dermatitis, scalp irritation, and headache, which were more evident in Group B than in Group A.</p><p><strong>Conclusions: </strong>Both topical spironolactone and topical minoxidil were cheap, safe, and effective lines for the treatment of FPHL with minimal and tolerable side effects.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"42-50"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractory Folliculitis Decalvans: New Therapeutic Horizons?","authors":"Ana Gabriella Bandeira Freire Andrade, Camila Raposo Cabral Scuotto, Dimitri Luz Felipe Da Silva","doi":"10.4103/ijt.ijt_83_23","DOIUrl":"10.4103/ijt.ijt_83_23","url":null,"abstract":"<p><p>Folliculitis decalvans (FD) poses a significant challenge due to treatment resistance and relapses. We report a case of FD refractory to various treatments for 15 years, where initiating adalimumab led to an excellent response. Male patient, 33 years, throughout the 15-year follow-up followed up due to a confirmed diagnosis of FD, underwent several cycles of antibiotics, besides the use of isotretinoin and dapsone, at different times, both without clinical improvement. Understanding that the diagnosis of FD falls within the spectrum of hidradenitis suppurativa (HS), we decided to started adalimumab with a dosage regimen specific to HS and we used the HS physician global assessment (HS-PGA) score to assess the improvement. After 13 weeks, the patient showed significant improvement going from a severe to mild rating by the HS-PGA score. Using a tumor necrosis factor-alpha (TNFα) blocker like adalimumab in treatment may be justified, since is an inflammatory cytokine commonly seen in neutrophilic dermatoses, including FD. The inappropriate cell-mediated immune response in FD leads to increased TNFα levels. However, further studies and broader monitoring of each case are necessary to better understand possible flare-ups during treatment and achieve lasting remission of the disease.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"66-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Durometer to Objectively Measure the Hardness of Skin in Linear Morphea.","authors":"Nithya Satish, Chakravarthi R Srinivas","doi":"10.4103/ijt.ijt_69_22","DOIUrl":"10.4103/ijt.ijt_69_22","url":null,"abstract":"<p><p>A 7-year-old female child presented with a linear depressed lesion involving the forehead and frontoparietal region of the scalp and was diagnosed as en coup de sabre. Following treatment with soap Psoralen combined with ultraviolet A (UVA) therapy and topical corticosteroid and calcipotriol combination, there was significant resolution of the induration, and in addition, there was partial regrowth of the hair. The resolution of the induration could be objectively documented using a durometer. We used shore durometers, which are simple, handheld measuring devices with a wider range of durometer scores that use specific, standardized techniques to measure the hardness. Durometers provide an accurate, scalable measurement with an ease of detecting change. Variation in the durometer readings corresponds to the change in disease activity.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"17 1","pages":"77-79"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abametapir: A New Solution to an Age Old Problem.","authors":"Atreyo Chakraborty","doi":"10.4103/ijt.ijt_77_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_77_22","url":null,"abstract":"<p><p>Abametapir is a new metalloproteinase inhibitor that received Food and Drug Administration approval in July 2020 as a topical pediculocide. The uniqueness of this new drug is that it targets metalloproteinase needed for hatching the eggs as well as killing adults. Herein we discuss this new drug, its history of development, its modality of use and its adverse drug reactions. It is hoped it will make Dermatologists aware of this new development.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"55-57"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID Curls: A Striking Change in Hair Texture Following COVID-19 Infection.","authors":"Sabrina Khan, Natalia Vecerek, Maria Teresa Ochoa, Brandon L Adler","doi":"10.4103/ijt.ijt_51_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_51_22","url":null,"abstract":"<p><p>Although hair loss following severe acute respiratory syndrome-coronavirus-2 (COVID-19) infection is common, there are no reported cases of textural changes in COVID-19-associated alopecia. Here, we describe a case of diffuse hair loss followed by distinct changes in hair morphology 1 year after symptomatic COVID-19 infection. Clinical findings were most consistent with anagen effluvium. Robust inflammatory response following COVID-19 infection may contribute to changes in hair texture.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"45-46"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traction Alopecia Prevention Intervention Program in Keffi, Nigeria: A Preliminary Report.","authors":"Obumneme Emeka Okoro, Rachel Barminas, Abubakar Imam","doi":"10.4103/ijt.ijt_43_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_43_22","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"63-64"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hair Root Dermoscopy from Shed Hair: A Simple Diagnostic Tool in Telogen Effluvium.","authors":"Namrata Chhabra, Jemshi S Rahim","doi":"10.4103/ijt.ijt_121_21","DOIUrl":"https://doi.org/10.4103/ijt.ijt_121_21","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"58-59"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on Current Investigations into the Postfinasteride Syndrome.","authors":"Ralph Michel Trüeb, Ngoc-Nhi Catharina Luu, Natalia Caballero-Uribe, Reis Gavazzoni Dias, Hudson Dutra Rezende","doi":"10.4103/ijt.ijt_122_21","DOIUrl":"https://doi.org/10.4103/ijt.ijt_122_21","url":null,"abstract":"<p><p>Few dermatologic problems carry as much emotional overtones as the complaint of hair loss, while the best way to alleviate the emotional distress related to the hair loss is to effectively treat it. With the advent of effective pharmacologic agents, the options for managing male pattern hair loss (MPHL) and alopecia-related distress have expanded. Oral finasteride represents a major breakthrough, based on an understanding of the underlying pathophysiology, and observations on the phenotype of the respective genetic defect of type 2 5-alpha reductase. Clinical studies have demonstrated both a high efficacy of treatment and a favorable safety profile establishing the drug as first-line treatment. And yet, after 15 years of successful prescription, the postfinasteride syndrome has emerged. By definition, the condition is characterized by sexual dysfunction, somatic symptoms, and psychological disorders that persist after cessation of treatment. As yet, the condition is not recognized by the medical community. In fact, the concept has emerged from neuroendocrinological research and rodent models, while hair experts have performed investigations into the plausibility of the syndrome based on a comprehensive review of the respective medical literature, and found that persistent sexual side effects were only documented in low-quality studies with strong bias selection, and a significant nocebo effect. In fact, there is more evidence that the condition may represent a psychiatric disorder. In favor of this hypothesis are a striking similarity to Koro with regard to genital symptoms; emergence of the condition with media coverage; a known significant nocebo effect in patients informed about adverse effects of finasteride; high prevalence of personality disorders among men seeking treatment for MPHL; so far no consistent endocrinological or organic abnormalities; and quality of centrality: No matter how unlikely it is that these strange things are happening, the patient accepts them relatively unquestioningly.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"6-12"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}