Environment & Health最新文献

{"title":"Long-term dynamics of resistance to occupational burnout in pedagogical staff of different types of educational institutions","authors":"© Калиниченко, Латіна Г.О Стаття","doi":"10.32402/dovkil2022.03.029","DOIUrl":"https://doi.org/10.32402/dovkil2022.03.029","url":null,"abstract":"Objective: The aim of the study was to assess the level of professional burnout among teachers of educational institutions of various types in the long-term dynamics, taking into account the forms of work organization. Materials and methods: During 2008 - 2021 the level of occupational burnout was monitored in 852 pedagogical workers of the Sumy region. The study was carried out according to the method of V. V. Boyko «Diagnostics of the level of occupational burnout». The study included three stages. In 2008, 420 teachers of secondary education institutions were surveyed. In 2020, 342 teachers of preschool and primary schools were examined. In 2021, 85 teachers of secondary education institutions were examined. In 2021, the organization of the educational process was taken into account. It included an online format in the context of the COVID-19 pandemic caused by the SARS-CoV-2 coronavirus, taking into account a history of coronavirus disease. Results: During the entire observation period, a low level of occupational burnout prevailed among teaching staff. Over the years, there has been a steady trend in the spread of the average level of occupational burnout, which has a negative sign of a protracted course with regular symptoms. The dependence of the development of the general syndrome of occupational burnout on age was established (r=-0,87, p<0,01). In 2008, occupational burnout was formed at the expense of teachers aged 31-40 years old. In recent years of observation, all levels of occupational burnout were formed at the expense of teachers aged 51 years old and more. Thus, the teachers retained the features of the psycho-emotional state with manifestations of occupational burnout after twelve years of observation and formed groups with high occupational burnout at the time of the re-examination. As of February 2021, 63,53% of teaching staff in the observation group had a history of coronavirus disease. Regardless of this, there was a general tendency among pedagogical workers for the advantage of low and medium levels of occupational burnout over high. A high level of professional burnout among teachers who underwent COVID-19 (9,26±0,95 %) was recorded in 3,64%, which is less than the same group of teachers (with a high level of professional burnout) without a history of COVID-19 (12,90±1,34 %, t=2,21, p<0,05). It has been established that the development of professional burnout is not associated with the psycho-emotional state of the coronavirus disease, since the main factors in the formation of professional burnout are the organizational factors of the labor process. Conclusions: During 2008-2021, teachers experienced an increase in the rate of development of occupational burnout. The dependence of occupational burnout on age has been established.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"49 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125354689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of polyphenol compounds in medicinal plants of local habitat and their importance for health","authors":"O. Pylypenko, L. Sukhovirska, N. Operchuk","doi":"10.32402/dovkil2022.03.057","DOIUrl":"https://doi.org/10.32402/dovkil2022.03.057","url":null,"abstract":"Objective: Assess the possibility of using some medicinal plants containing polyphenolic compounds (tannins and gallic acid) in medicine. Materials and methods: The Folin-Ciocalteu reagent spectrophotometry method is used to determine the amount of polyphenolic compounds. The gallic acid solution was selected as the standard sample. The objects of the study were dry specimens of plants: Oak Bark (quercus cortex), Rhizomes of Bistorta officinalis (bistortae rhizomata), Galls of Oak leaves (gallae turcicae), Rhizomes of Potentilla erecta (tormentillae rhizomata). Experimental samples in the form of aqueous and alcoholic extracts are made from this dry raw material. Results: Studies have shown that all selected plants have sufficient tannin content to confirm their healing properties. The largest number was found in the galls of oak leaves. Alcohol extracts extracted polyphenolic compounds from plant raw materials better than aqueous ones, but the difference is relatively small. Therefore, aqueous extracts can be used as therapeutic drugs for those who are contraindicated alcohol extracts. Conclusions: The studied dry specimens of plants (oak bark (quercus cortex), rhizomes of snake mustard (bistortae rhizomata), galls of oak leaves (gallae turcicae), rhizomes of erect cinquefoil (tormentillae rhizomata)) contain polyphenolic compounds (tannin and gallic acid) in sufficient quantities to provide medicinal effect. It has been shown that the extraction of polyphenolic compounds from plant materials using alcohol solutions is more efficient than aqueous extracts. It is recommended to use herbal products with tannins in medicinal practice.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122625035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The difference of the concept of \"malady\" in the context of public health: (part 1 - analytical research)","authors":"O. Berdnyk, T. Skochko, O. Dobrianska, О. Rudnytska","doi":"10.32402/dovkil2022.03.004","DOIUrl":"https://doi.org/10.32402/dovkil2022.03.004","url":null,"abstract":"Target. From the standpoint of public health, analyze scientific literature data and terminology related to various hypostases / manifestations of malady. Materials and methods. The analysis of domestic and foreign publications devoted to terminological issues of assessing various aspects of the incidence of the population. Results. The state of research concerning various aspects of the concept of \"disorder\" in the scientific domestic and foreign literature has been determined. A review of the scientific literature revealed a lack of theoretical provisions on this topic that could be generalized, compared and contrasted. In everyday English, the use of concepts to describe malady (disease, illness, sickness, etc.) is often seen as arbitrary, and in the scientific field, they are the subject of professional discussions. For Ukraine, the analysis of malady terminology is new. The designation of the space for the use of certain terms is important, since the study of various aspects of the malady involves the use of various methods of collecting information, interpreting the data obtained, conclusions about ways to overcome disorders, etc. The definition of malady is not only a theoretical issue: it is important for medicine, social policy and the health care system in general. For public health, which is the most socially oriented branch of medicine, it is extremely important to take into account not only the purely biomedical (disease), but also the social (sickness) aspects of the disorders, as well as its self-esteem (illness).The combination and interrelation of various hypostases of the disorders included in the Twaddle triad is considered, a comparative analysis of its components has been carried out. The relevance of the analysis of the morbidity of the population and the justification of the most effective health-improving measures determines the advisability of taking into account various hypostases of ill health, and given the multidisciplinary nature of public health, the involvement of specialists in various fields.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123059936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific substantiation of standards of health physical activity for primary-school-age children","authors":"S. Hozak, O. Yelizarova, I. A. Kalinichenko, T.V. Stankevych, A. Parats","doi":"10.32402/dovkil2022.03.037","DOIUrl":"https://doi.org/10.32402/dovkil2022.03.037","url":null,"abstract":"The aim of the study was to determine the optimal volume of primary-school-age children's physical activity to improve their adaptive capabilities. Materials and methods. The features of physical activity, social factors, anthropometric, and physiological parameters of 297 students in grades 1-4 of schools in Sumy were studied using diaries that parents filled out during the week and examination by a paediatrician (2016). The duration of moderate-to-vigorous physical activity (MVPA) was determined. The adaptive-reserve capabilities (ARV) integral indicator was calculated. ARV due to the characteristics of physical development, and the functioning of the autonomic nervous and cardiovascular systems of the child. Descriptive statistics, contingency tables, dispersion, correlation analysis, and linear regression models were used. Results. We have established that the proportion of children with an unsatisfactory level of adaptive-reserve capabilities among primary-school-age children was about 40%. A trend towards a decrease in ARV in children with chronic diseases was revealed. A relationship between ARV and the duration of sports activities was established (p<0.01). The total value of MVPA was 215.2±16.6 min/week for boys and 189.0±14.0 min/week for girls (p>0.2). The weekly duration of MVPA in children who play organized sports is higher than in those who do it on their own (p<0.001). Estimated health-saving values of MVPA are from 43 to 68 minutes/day with an average value of 55 minutes for boys and from 37 to 61 minutes/day with an average value of 50 minutes for girls. Non-compliance with these norms can lead to a decrease in ARV, especially in the group of children with chronic diseases. Conclusions: The average duration of daily MVPA (with energy consumption of more than 3 METs) should be 55 minutes for boys and 50 minutes for girls for increasing the adaptive-reserve capabilities of children in the age group of 6-10 years.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"184 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124668065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the potential toxicity of detergents with disinfectants properties on cell culture in vitro","authors":"N. Dmytrukha, T. K. Korolenko, O. Lahutina, L. A. Lehkostup","doi":"10.32402/dovkil2022.02.004","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.004","url":null,"abstract":"Detergents with disinfectants properties today are widely used in various fields of human activity for cleaning surfaces, equipment, tools while destroying infectious agents. An active substance, as disinfectants, it contains various chemical compounds with antimicrobial, antiviral and antifungal properties. To establish the safety of these substances, along with toxicological studies on animals, experiments are conducted on alternative in vitro test systems, in particular on cell culture, which allows to quickly assess and predict the potential toxicity of detergents to humans and other living organisms. The purpouse of the study was assessment of the potential danger of detergents and disinfectants for humans by determining their cytotoxic effects in experiments on cell culture in vitro. Material and methods. Studies were performed to evaluate the cytotoxic effect of detergents with disinfectants properties : \"Bioblysk\", \"Blysk Plus\" and \"Blysk\" (manufactured by PE \"HYGIENICS\", Poland) on the lung cancer cells (line A-549) using cytochemical methods: MTT- with methyltetrazolium blue and CRB - test with sulforodamine B. Results. It was found that all detergents have the greatest cytotoxic effect on A-549 cells at a concentration of 1.0% of the native solution. The lowest concentrations 0.03% and 0.015% have no toxic effect on cells. With the help of probit analysis based on the obtained results, LC50 values were calculated: for Bioblysk - 0.15% (MTT test) and 0.15% (CRP test); for Blysk Plus LC50 - 0.25% (MTT test) and 0.2% (CRP test); for Blysk - 0.2% (MTT test and CRP test). LC50 values for detergents were 10 times lower than the recommended minimum concentrations of working solutions Conclusions. The obtained data indicate that the citotoxicity effect of detergents on A-549 cells was manifested by the effect on mitochondrial function and protein synthesis. The severity of studied drugs toxic effect depended on its chemical composition and pH, concentration in the incubation medium. The calculated LC50 values indicate their possible danger to the respiratory system, so they require appropriate protection.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121586578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic control of homocysteine metabolism in children living near the chоrnobyl exclusion zone","authors":"Yu.I. Bandazhevskyi, N. Dubova","doi":"10.32402/dovkil2022.02.010","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.010","url":null,"abstract":"The aim of study: to determine the involvement of folate cycle genes in the occurrence of hyperhomocysteinemia in children from Ivankivskyi district of Kyiv region of Ukraine 35 years after the accident at the Chornobyl nuclear power plant. Research methods. Immunochemical, mathematical and statistical. Results. Homocysteine levels were determined in 217 children aged 12-17 from Ivankivskyi district of Kyiv region, as well as genetic polymorphisms of the folate cycle. An excess of homocysteine in the blood over 10 µmol/l (a state of hyperhomocysteinemia) was detected in 65.44 % (142 out of 217) of those examined, among boys – 69.79 % (67 out of 96), among girls – 61.98 % (75 out of 121). The largest proportion of hyperhomocysteinemia cases was registered in the subgroup of children with the basic polymorphism MTHFR: 677TT – 94.44 % of cases. In most cases, hyperhomocysteinemia in children was associated with an environmental factor, including radioactive elements and their decay products. The system for the prevention of hyperhomocysteinemia and its consequences in children living in areas affected by the accident at the Chornobyl nuclear power plant should include regular monitoring of the content of radionuclides in the body of children and locally produced food, the content of homocysteine in the blood, and assessment of the state of folate cycle genes.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123539757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer incidence in the population of Ukraine in remote period after the Chornobyl accident","authors":"A.Ye. Prysyazhniuk, D. Bazyka, N.A. Hudzenko, M. Fuzik, N. Trotsiuk, N. Babkina, O. Khukhrianska, S. A. Danevych","doi":"10.32402/dovkil2022.02.016","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.016","url":null,"abstract":"There is performed a study of cancer incidence in the population affected by the Chornobyl accident. Analysis of demography situation has shown that unlike Western European countries with increasing life expectancy this index was notably decreased in Ukraine in 2005–2006 with slow growth during 2006–2019. Certainly this circumstance may influence on cancer incidence rate because the highest risk of malignant tumours is just in elderly age. Goal: to determine the frequency and risk of malignant neoplasms in groups of the population of Ukraine that were exposed to radiation as a result of the Chоrnobyl accident in the remote post-accident period. Materials and methods. The study was conducted on the basis of long-term monitoring of malignant tumours in the groups of victims – clean-up workers of 1986–1987, evacuees from the exclusion zone, residents of the territories most heavily contaminated with radionuclides. Results. There was a significant excess of the expected level of incidence of thyroid cancer among the participants in liquidation of the accident consequences (PLAC) - 4.5 times, evacuees - 3.8 times, residents of territories contaminated with radionuclides - 1.3 times. Leukaemia and lymphoma incidence rate in residents of contaminated territories increased sharply in the first years after the accident but decreased in the next years and not exceeded the level if Kyiv and Zhytomyr regions and Ukraine at whole. In a joint Ukrainian-American analytical epidemiological case-control study dose dependent excess relative risk of leukaemia (ERR/Gy) was proved in clean-up workers and defined at level 2.38 (0.49–5.87) in 1986–2006. A significant excess of the national level of incidence of breast cancer was determined only in women - PLAC in 1986–1987. In 1994–2019 SIR was 156.3% (95% CI: 141.0–171.5). Conclusions. Because latency period for different forms of radiation related malignancies might be very long further special attention should be paid not only to nosological forms mentioned above but also to cancers of the other sites.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129976820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The state of occupational stress in medical workers, counteraction and overcoming it","authors":"V. Chorna, V. Makhniuk, S.M. Моhylnyi, S. Khliestova, V.M. Podolian, L. B. Furman, I. V. Larchenko, A. Chaika","doi":"10.32402/dovkil2022.02.053","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.053","url":null,"abstract":"Objective. To determine the manifestations and the level of predictors of the development of emotional burnout (PREV) among medical workers in the Vinnytsia region and develop preventive measures to prevent it. Materials and methods. The study involved 324 respondents - healthcare workers in the Vinnytsia region. Among the respondents were women – 82,4%, men – 17,6%. The average age of respondents among doctors was 44,06+12,2 years, among nurses – 37,2+11,4 years. The length of service in professional activities was: among doctors – 19,7 + 12,3 years and SMPs – 15,5 + 11,1 years. The psychodiagnostic method of emotional burnout by V.V. Boyko was used in the study and the adapted technique of N.E. Vodopianova. Statistical processing of the study results was performed in the licensed standardized package Statistica 6.1 for Windows with the calculation of the arithmetic mean value, the standard mean arithmetic error. The significance of the difference was assessed using Student's t-test (t). The work used content analysis of domestic and foreign scientific sources, biblio-semantic, analytical and statistical research methods. Research Results. The article analyzes the state of professional and emotional burnout/stress among medical workers in the healthcare sector in Ukraine and abroad. The chief causes of professional burnout/stress, their factors, and their consequences are highlighted. Conclusions. These research results indicate inappropriate working conditions and the presence of harmful professional factors leading to a high level of emotional exhaustion, depersonalization, and a reduction in professional achievements, which negatively affects the performance of their professional duties by every second health worker and requires them to be provided with outpatient treatment to prevent the transition of PREV syndromes and professional burnout into illness. The prospect of further research is to study the problem of professional burnout/stress, counteraction, and an effective system of mental health prevention both for medical personnel and the population of Ukraine.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127429343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychogygenic principles of using health-preserving technologies in modern institutions of higher education","authors":"I. Serheta, N. V. Stoian, O. Serebrennikova, I. Drezhenkova, O. Makarova","doi":"10.32402/dovkil2022.02.032","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.032","url":null,"abstract":"Objective: We established and scientifically substantiated the psychohygienic principles of using health-preserving technologies in modern institutions of higher education. Materials and methods. The research was conducted on the basis of National Pyrohov Memorial Medical University. A well-structured set of highly informative modern hygienic, medical-sociological, psychophysiological and psychodiagnostic methods and methods of statistical analysis were used to adequately achieve this goal. Results. The data obtained in the course of research indicate that as conceptual psychohygienic principles of effective use of health-preserving technologies in modern institutions of higher education should be noted: (1) regime-adaptive principle of application of psychohygienic components in the structure of modern health-preserving technologies, which determines the need to take into account the main regime elements of educational and extracurricular activities of students in specific conditions of the educational process, determining and constantly monitoring the level of educational adaptation and academic performance of students, especially in professionally oriented disciplines; (2) psychophysiological principle of application of psychohygienic components in the structure of modern health technologies, which is determined by the level of development of leading socially and professionally significant psychophysiological functions of the body of girls and boys; (3) personal principle of application of psychohygienic components in the structure of modern health technologies, which is related to the peculiarities of assessing the processes of formation of leading personality traits of student youth, which play an important role under the influence of both favorable and, above all, unfavorable educational factors. extracurricular activities; (4) integrative-functional principle of application of psychohygienic components in the structure of modern health technologies, which is determined by the presence of deep relationships between individual components of the functional state and adaptive capacity of young girls and young boys, which have a complex impact on health and theoreticalу- and, mainly, practically-significant components of students’ training. Conclusions. In the course of the research the leading psychohygienic principles of using health-preserving technologies in modern modern institutions of higher education have been identified and scientifically substantiated.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126870468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the issue of revising the regulatory framework for chemical carcinogens in the air according to the risk criterion","authors":"I. Chernychenko, O. Lytvychenko, V. Babii, S. Harkavyi, N. Balenko, O.Ye. Kondratenko, D. Hlavachek","doi":"10.32402/dovkil2022.02.042","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.042","url":null,"abstract":"The aim of the work was to analyze the risk of carcinogenic substances in populated areas and industrial zone, included in domestic regulatory frameworks, in accordance with international qualification standards, and to determine the safety level of existing hygienic standards for humans by specific oncogenic hazard criteria. Materials and methods. Bibliosemantic, bibliographic and hygienic research methods was used in the work. The results were obtained on the basis of collection and analysis of data on chemical carcinogenic compounds that are dangerous to humans, according to international directives, domestic and foreign regulatory frameworks. Carcinogenicity indicators was identified to assess the hazards of certain substances and hygienic regulatory levels. Research results and their discussion. The analysis of national and international databases on carcinogenic compounds, assessment of their physicochemical properties, dose-effect response and health effects was carried out. It was shown that today the most recognized and widespread base of the International Agency for Research on Cancer, in which based on a critical analysis of experimental and epidemiological data of more than 1000 chemical factors, their classification was carried out according to the degree of evidence of carcinogenic hazard to humans, the hygienic expression of which is carcinogenic risk. The analysis of domestic databases of hygienic standards for the permissible content of chemicals showed that only for 131 carcinogenic substances the MPC in the air is justified, however, according to the criterion of carcinogenic risk, most of them do not meet the requirements of the EU and world practices, which indicates the need for their revision. It is emphasized that one of the available and adequate methods of this task is the principle laid down in determining the relationship \"concentration - risk (acceptable risk)\". Conclusions. It was shown that according to the criterion of carcinogenic risk, the hygienic standards of most carcinogenic substances included in domestic regulatory air bases do not meet the requirements of the EU and international practices, which indicates the need to revise them based on acceptable risk.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125141339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}