International journal of pediatric otorhinolaryngology最新文献

{"title":"Retrospective long-term analysis of tympanoplasty in children","authors":"Osikhe Ejeah-Braimoh,&nbsp;Bastian Baselt,&nbsp;Christof Röösli","doi":"10.1016/j.ijporl.2025.112474","DOIUrl":"10.1016/j.ijporl.2025.112474","url":null,"abstract":"<div><h3>Objective</h3><div>Tympanoplasty is a well-established surgical intervention for tympanic membrane perforation (TMP) in children, aiming to restore anatomical integrity and improve auditory function. However, long-term outcomes remain variable, and factors influencing surgical success are still debated. This study evaluates anatomical and functional outcomes of pediatric tympanoplasty over a five-year follow-up period, with a particular focus on the influence of age and other prognostic factors.</div></div><div><h3>Methods</h3><div>A retrospective single-center cohort study was conducted at a tertiary referral hospital, including pediatric patients (≤16 years) who underwent tympanoplasty for TMP between January 01, 2012 and December 31, 2022. Data were retrieved from electronic hospital records, including operative reports, audiometric evaluations, and follow-up documentation. Primary outcomes were anatomical success (intact tympanic membrane at follow-up) and functional success (air-bone gap &lt;20 dB). Secondary outcomes included postoperative complications and factors influencing surgical success.</div></div><div><h3>Results</h3><div>A total of 111 ears (96 patients) were analyzed, with a mean follow-up of 17.9 months (range 3–60 months). The overall anatomical success rate at five years was 57.9 % and functional success at five years was 69.4 %. No significant correlation between age and anatomical or functional outcomes was found, except at 12-months-follow-up, there was a statistically significant advantage for older patients in functional success. Perforation size and etiology significantly impacted success rates, with smaller and infection-related perforations demonstrating better outcomes.</div></div><div><h3>Conclusion</h3><div>Tympanoplasty in children can result in favorable functional outcomes and moderate long-term anatomical success. No consistent age-related effect was observed, suggesting that surgical timing should be based on individual clinical factors rather than age alone. Perforation size and location as well as etiology emerged as more relevant prognostic factors. Future prospective multicenter studies are needed to validate these findings and guide patient selection.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112474"},"PeriodicalIF":1.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of type 1 diabetes mellitus on hearing function in children: A systematic review","authors":"Saransh Jain ,&nbsp;Chetak K B ,&nbsp;Sanjana Singh ,&nbsp;Varsha Chowdri N","doi":"10.1016/j.ijporl.2025.112476","DOIUrl":"10.1016/j.ijporl.2025.112476","url":null,"abstract":"<div><h3>Objectives</h3><div>Type 1 diabetes mellitus (T1DM) is associated with neuropathy, retinopathy, and nephropathy. However, its effect on hearing in children is not explicitly explored. This systematic review specifically focused on the hearing abilities of children with T1DM.</div></div><div><h3>Methods</h3><div>PubMed, Science Direct, and Scopus databases were searched for 20 years (January 2004–December 2024), following the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Two independent reviewers screened, selected, and extracted data. The Joanna Briggs Institute Critical Appraisal Tools for Analytical Cross-Sectional and Case-Control Studies were utilized to assess the quality and conduct a risk of bias analysis on the eligible studies.</div></div><div><h3>Results</h3><div>After screening 1784 studies, 12 met the inclusion criteria for the review on the impact of T1DM on hearing function in children. A total of 1143 children aged 4–18 years were analysed across these 12 studies. The findings were heterogeneous, with some studies reporting elevated pure tone thresholds (particularly at mid to high frequencies), reduced otoacoustic emission amplitudes, and delayed auditory brainstem response latencies, while others showed no significant auditory differences between T1DM and control groups. Further, longer disease duration (more than 5 years), poor glycaemic control, and diabetes induced micro-vascular changes were associated with increased auditory deficits in several studies.</div></div><div><h3>Conclusion</h3><div>This systematic review shows a potential association between T1DM and hearing impairment and highlights the importance of risk-based audiological monitoring in paediatric diabetic populations. While the evidence does not support universal screening, targeted evaluations for high-risk individuals (e.g., those with poor glycaemic control or longer disease duration) may enable earlier detection and intervention. Regular monitoring can help in the early detection of hearing loss so that timely support can be provided, leading to better language skills, school performance, and overall quality of life for children.</div></div><div><h3>Registration</h3><div>Registered in PROSPERO (CRD42024625363).</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112476"},"PeriodicalIF":1.2,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144588083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of unmet social needs on timing of tympanostomy tube placement","authors":"Molly O. Meeker ,&nbsp;Jemma Maynard ,&nbsp;Aidan Vanek ,&nbsp;Alexandra Gach ,&nbsp;Tatum Adamson ,&nbsp;Kolby Quillin ,&nbsp;Isaac Kistler ,&nbsp;Prasanth Pattisapu ,&nbsp;Charles Elmaraghy","doi":"10.1016/j.ijporl.2025.112472","DOIUrl":"10.1016/j.ijporl.2025.112472","url":null,"abstract":"<div><h3>Introduction</h3><div>Unmet social needs (USN) focus on individual patient concerns; they are less dependent on geography than other social determinants of health (SDOH). Here we aim to characterize the impact of various USN on timing of tympanostomy tube (TT) placement.</div></div><div><h3>Methods</h3><div>A retrospective chart review of 815 patients 0–4 years old with first-time TT placement at our institution between January 1st, 2023, and July 1st, 2023, was conducted. The risk of each USN were recorded for patients according to the electronic medical record.</div></div><div><h3>Results</h3><div>Our study found that in the presence of any USN, the at-risk group (AR) had a 19 % longer time between surgery order and surgery than the not-at-risk group (NAR) (IRR1.19, 95 %CI 1.15–1.22,p &lt; 0.01), which remained significant when adjusted for race and insurance (R/I) (IRR1.15, 95 %CI 1.11–1.18,p &lt; 0.01), and race, insurance and clinical factors (R/I/C) (IRR1.10, 95 %CI 1.07–1.13,p &lt; 0.01). When evaluating time from last reported ear infection to initial evaluation by otolaryngology, we found that for any USN, the AR group had a shorter time to presentation than the NAR, with the effect remaining significant in our adjusted models for R/I, and R/I/C (IRR0.97; 95 %CI 0.94–0.99,p = 0.02 and IRR0.81; 95 %CI 0.79–0.83,p &lt; 0.01 and IRR0.70; 95 %CI 0.68–0.73,p &lt; 0.01, respectively).</div></div><div><h3>Conclusions</h3><div>This study demonstrated that patients with any USN had a significantly longer time from surgery order to surgery than those NAR. The data suggests that USN and SDOH have a nuanced and interdependent relationship regarding delays in care. This study highlights specific USN that institutions can target to mitigate delays in care.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112472"},"PeriodicalIF":1.2,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes of autophagy related proteins during sublingual immunotherapy treatment in allergic rhinitis","authors":"Chunrui Wang,&nbsp;Li Jiang,&nbsp;Xiaowei Qin,&nbsp;Tianhong Zhang","doi":"10.1016/j.ijporl.2025.112477","DOIUrl":"10.1016/j.ijporl.2025.112477","url":null,"abstract":"<div><h3>Background</h3><div>Allergic rhinitis (AR) affects the nasal mucosa, causing significant quality of life impairments. Sublingual immunotherapy (SLIT) is effective in mitigating AR symptoms. Autophagy regulates immune responses and is implicated in AR. We aimed to investigate the impact of SLIT on autophagy-associated proteins and their relationship with Th1 and Th2 cytokines in AR patients.</div></div><div><h3>Methods</h3><div>Sixty AR children were recruited. They underwent standardized SLIT with Der f extract. Efficacy was evaluated using combined symptom and medication score (CSMS). Blood samples were analyzed for autophagy-related proteins (ATG5, p62, Beclin-1, LC3I, LC3II) and Th1/Th2 cytokines (IFN-γ, IL-4).</div></div><div><h3>Results</h3><div>After 3 years’ SLIT, ATG5, LC3I, LC3II, and Beclin-1 expressions decreased, while p62 increased. Th1 cytokine expression increased, and Th2 cytokine expression decreased. The effective group showed greater changes in protein expression compared to the ineffective group. A positive correlation was found between autophagy-associated protein expression and Th2 cytokines.</div></div><div><h3>Conclusion</h3><div>SLIT alters autophagy-related protein levels and reverses the Th1/Th2 balance in AR patients, suggesting autophagy-associated proteins as potential biomarkers for SLIT efficacy.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112477"},"PeriodicalIF":1.2,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ossicular chain reconstruction in children: Outcomes of autologous incus interposition and TORP","authors":"Aynur Aliyeva ,&nbsp;Elvin Alaskarov","doi":"10.1016/j.ijporl.2025.112473","DOIUrl":"10.1016/j.ijporl.2025.112473","url":null,"abstract":"<div><h3>Aim</h3><div>To compare hearing outcomes and prognostic factors in pediatric patients undergoing ossiculoplasty with autologous incus interposition (AII) or total ossicular replacement prosthesis (TORP).</div></div><div><h3>Methods</h3><div>This retrospective study included 102 children under 18 who underwent tympanoplasty with ossicular reconstruction between 2021 and 2024. Patients were divided into two groups based on reconstruction type (AII or TORP). Audiological outcomes were assessed at short-term (6–12 months) and middle-term (&gt;12 months) follow-up. Air conduction (AC), bone conduction (BC), and air-bone gap (ABG) thresholds were measured. Multivariate logistic regression was used to identify predictors of ABG closure ≤20 dB.</div></div><div><h3>Results</h3><div>Among the 102 patients, 52 underwent AII, and 50 received TORP. At middle-term follow-up, ABG ≤ 20 dB was achieved in 72.5 % of AII patients versus 39.5 % in the TORP group (p = 0.003). AII patients also showed better AC thresholds (≤30 dB in 75.0 % vs. 57.9 %, p = 0.005) and greater hearing gain (13.1 ± 3.8 dB vs. 12.2 ± 4.3 dB, p = 0.028). Multivariate analysis identified intact stapes and AII use as independent predictors of success. Outcomes were also more favorable in cholesteatoma cases when the stapes were preserved.</div></div><div><h3>Conclusion</h3><div>AII offers superior middle-term hearing outcomes compared to TORP in pediatric ossiculoplasty. Stapes preservation and appropriate reconstruction technique selection are essential for optimal results.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112473"},"PeriodicalIF":1.2,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital versus traditional otoscopy in the diagnosis of acute otitis media in the pediatric primary care clinic","authors":"Henry Zheng ,&nbsp;Jun Chen ,&nbsp;Jing MacKenzie ,&nbsp;Stanley Mui ,&nbsp;Nancy Jiang","doi":"10.1016/j.ijporl.2025.112453","DOIUrl":"10.1016/j.ijporl.2025.112453","url":null,"abstract":"<div><h3>Objectives</h3><div>Our objective was to assess whether the use of digital otoscopy versus traditional otoscopy in a pediatric clinic setting leads to decreased rates of antibiotic prescriptions and follow-up visits. Secondary outcomes included photo viability and both patient and provider satisfaction.</div></div><div><h3>Methods</h3><div>This was a prospective study in which both digital otoscopes and traditional otoscopes were deployed at two different pediatric offices during an eight-week pilot period. The treatment group consisted of 35 patients who received ear exams with digital otoscopy while the control group consisted of 586 patients who received ear exams with traditional otoscopy. Measured outcomes included rates of antibiotic prescription and follow-up visits, photo viability, and both patient and provider satisfaction.</div></div><div><h3>Results</h3><div>Comparing the treatment group with the control group, the average number of visits per patient decreased by 0.14 from 1.14 to 1.0, (p = 0.007). The number of antibiotic prescriptions per patient decreased by 0.31 from 0.88 to 0.57 (p = 0.0008). The overall experience with digital otoscopy was rated as good or excellent in 94 % (16/17) of patients. Seventy-three percent (8/11) of providers rated the digital otoscope as excellent or good compared to traditional otoscopes, and 82 % (9/11) stated that they were extremely likely or likely to continue using the digital otoscope in their practice.</div></div><div><h3>Conclusion</h3><div>The use of digital otoscopy versus traditional otoscopy in a pediatric clinic setting was associated with significant decreases in follow-up visit volumes as well antibiotic prescriptions. Implementing digital otoscopy more widely may contribute to decreased healthcare utilization costs and improved antibiotic stewardship for acute otitis media.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112453"},"PeriodicalIF":1.2,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144569854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors associated with postoperative complications in pediatric thyroidectomy: A single-center Vietnamese experience","authors":"Quy Xuan Ngo ,&nbsp;Duong The Le ,&nbsp;Duy Quoc Ngo","doi":"10.1016/j.ijporl.2025.112471","DOIUrl":"10.1016/j.ijporl.2025.112471","url":null,"abstract":"<div><h3>Background</h3><div>Pediatric thyroid carcinoma presents unique surgical challenges, with potentially significant postoperative complications affecting long-term developmental outcomes. This investigation aimed to evaluate postoperative complications following thyroidectomy in pediatric patients and identify associated prognostic factors within a high-volume Vietnamese surgical center.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted on 112 pediatric patients (≤18 years) who underwent thyroidectomy for differentiated thyroid carcinoma between January 2014 and January 2023. Primary outcomes included the incidence and characteristics of postoperative complications, particularly focusing on recurrent laryngeal nerve injury and hypoparathyroidism. Risk factors were evaluated using univariate and multivariate analyses.</div></div><div><h3>Results</h3><div>The cohort predominantly comprised female patients (68.8 %), with a mean age of 15.2 ± 2.7 years. Papillary thyroid carcinoma constituted 96.4 % of cases. Total thyroidectomy was performed in 70.5 % of patients, with central compartment lymph node dissection in 83.0 %. Transient recurrent laryngeal nerve dysfunction occurred in 16.1 % of cases, while transient hypocalcemia affected 24.1 % of patients. No permanent complications were observed. Multivariate analysis identified total thyroidectomy as an independent predictor of both complications (p &lt; 0.05). Central compartment nodal metastatic burden (&gt;5 nodes) significantly correlated with transient recurrent laryngeal nerve dysfunction (p &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>Low complication rates espicially the absence of permanent complications support the safety of thyroidectomy in pediatric single-center in Vietnam. The study underscores the importance of expertise in managing pediatric thyroid carcinoma, while identifying specific risk factors that may inform surgical decision-making and patient counseling.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112471"},"PeriodicalIF":1.2,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing age-specific protocols for pediatric voice databases in artificial intelligence research","authors":"Laurie Russell ,&nbsp;Yael Bensoussan ,&nbsp;Evan Ng ,&nbsp;Allistair Johnson ,&nbsp;Siyu Miao ,&nbsp;Nikolaus E. Wolter ,&nbsp;Evan J. Propst ,&nbsp;Jennifer M. Siu","doi":"10.1016/j.ijporl.2025.112455","DOIUrl":"10.1016/j.ijporl.2025.112455","url":null,"abstract":"<div><h3>Introduction</h3><div>Children's voice and communication abilities evolve with age, necessitating tailored protocols for accurate analysis. Distinct vocal properties and communication styles across developmental stages require specific tasks. The absence of standardized pediatric protocols impedes reliable voice data collection, limits robust acoustic measurements, and hinders AI-driven voice research. This study aims to develop age-specific voice data collection protocols, creating a pediatric voice database to advance research and enhance AI applications.</div></div><div><h3>Methods</h3><div>Protocols were developed iteratively over six months through a multidisciplinary, multi-institutional team involving speech-language pathologists and otolaryngologists. A comprehensive literature review was completed. Emphasis was placed on designing protocols capable of generating high-quality, consistent data for AI modeling while minimizing measurement variability.</div></div><div><h3>Results</h3><div>Four developmentally appropriate protocols were created for children aged 2 to &lt;4 years, 4 to &lt;6 years, 6 to &lt;10 years, and 10+ years respectively. Each protocol targeted key acoustic parameters while aligning with the linguistic and cognitive abilities of the respective age group. The iterative design incorporated tasks that engaged children while ensuring clinically robust data collection. Standardized protocols were deployed via a user-friendly iPad application, using child-sized headset microphones at fixed distances from the mouth. The protocols were administered to 100 pediatric patients in an otolaryngology clinic between the ages of 2–18.</div></div><div><h3>Conclusions</h3><div>The development of age specific protocols aims to standardize the collection of pediatric voice and acoustic sound data, which will serve as a valuable resource for advancing artificial intelligence applications within clinical sciences. Future validation will ensure feasibility, adherence, and reliability of data collection to support AI-driven innovations.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112455"},"PeriodicalIF":1.2,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144653357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Otolaryngologic manifestations of type 1 diabetes mellitus in paediatric populations: A systematic review","authors":"Saskia Boogaard ,&nbsp;Jeyasakthy Saniasiaya ,&nbsp;Craig McCaffer","doi":"10.1016/j.ijporl.2025.112458","DOIUrl":"10.1016/j.ijporl.2025.112458","url":null,"abstract":"<div><h3>Introduction</h3><div>Type 1 Diabetes Mellitus (T1DM) is a chronic autoimmune condition with systemic effects, including otolaryngologic (ORL) complications which are often overlooked. We conducted a literature review to investigate the ORL manifestations of T1DM in the paediatric population.</div></div><div><h3>Methodology</h3><div>A systematic literature search was conducted in October 2024 using the PubMed database. Studies reporting on ORL manifestations of paediatric T1DM were included.</div></div><div><h3>Results</h3><div>751 articles were identified, of which 20 met the selection criteria. A total of 950 patients were included, the mean age was 11.5 years. The majority were female (54 %). The most common paediatric ORL complications of T1DM studied were auditory, followed by vestibular, olfactory, and voice-related dysfunctions. The most common auditory findings were prolonged latency and reduced amplitude on auditory brainstem response testing. Nine studies reported that the duration and severity of T1DM was correlated with greater impairment. Subclinical ORL manifestations of T1DM were reported in seven studies. One study investigated quality-of-life and found that diabetic children have a lower overall quality of life than their non-diabetic peers.</div></div><div><h3>Conclusion</h3><div>In children, T1DM affects audio-vestibular, olfactory, and voice function to varying degrees. Routine ORL screenings in paediatric T1DM patients will ensure early detection and management. A checklist, including a thorough ORL history and examination, pure tone audiometry, brainstem auditory evoked potentials, olfactory testing, and quality of life measures, is recommended. Further longitudinal studies are needed to explore the progression of ORL manifestations in children with T1DM.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112458"},"PeriodicalIF":1.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Day-case Truly Scarless Endoscopic Tympanoplasty(TSET) with synthetic tissue graft in pediatric patients over 10 years old","authors":"Petros D. Karkos,&nbsp;George Psillas","doi":"10.1016/j.ijporl.2025.112451","DOIUrl":"10.1016/j.ijporl.2025.112451","url":null,"abstract":"<div><h3>Background</h3><div>to evaluate the success of Truly Scarless Endoscopic Tympanoplasty type 1 (TSET) in pediatric patients with the use of synthetic graft.</div></div><div><h3>Methods</h3><div>prospective study.</div></div><div><h3>Results</h3><div>during a 6 year period 12 children underwent TSET using four layered tissue graft (Biodesign, Cook medical). This was a strictly endoscopic procedure with an underlay technique. No conversion to microscopic surgery was deemed necessary and no incision outside the ear canal was made, hence the term Truly Scarless Endoscopic Tympanoplasty (TSET) procedure. Operative time ranged from 40 min to 130 min. There were 11 boys and 1 girl aged 11–16 years. All patients were discharged on the same day with no bandage and just a cotton wool in the ear canal. All grafts survived except one who ended with a microperforation (8,3 %) that did not require futher surgery. The failed case was one of a total perforation with was a revision case from another institution and throughout the operation had persistent hypertension and a less than ideal operative field. Follow up of all 12 patients ranged from 12 to 60 months.</div></div><div><h3>Conclusions</h3><div>TSET using synthetic material is an excellent alternative to classic pediatric tympanoplasty type I, it is painless, patients leave theatre with just a cotton wool in their ear canal, are discharged with no bandage, stitches or scars and is ideal for a day-case procedure. Success rates and graft failures are equivalent to classic ear microsurgery.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112451"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144535197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}