International journal of pediatric otorhinolaryngology最新文献

{"title":"Social determinants of health and effectiveness of social work support in a pediatric aerodigestive program","authors":"Shravan Asthana,&nbsp;Muhammad T. Hassan,&nbsp;Osama Hassan,&nbsp;Sawsan Alkhalili,&nbsp;Ariz Keshwani,&nbsp;Fernando Gonzalez,&nbsp;Taher Valika","doi":"10.1016/j.ijporl.2025.112459","DOIUrl":"10.1016/j.ijporl.2025.112459","url":null,"abstract":"<div><h3>Background</h3><div>Social determinants of health (SDOH) significantly influence the well-being of families in pediatric aerodigestive programs, affecting engagement with care, adherence to treatment, and overall health outcomes. This study evaluated the impact of SDOH and the effectiveness of social work support for families within a multidisciplinary aerodigestive program.</div></div><div><h3>Methods</h3><div>A mixed-methods study was conducted at Ann &amp; Robert H. Lurie Children's Hospital of Chicago using a convenience sample of patients discharged between July and August 2023. Data were collected through a condensed SDOH screening questionnaire, qualitative interviews, social work documentation, and chart reviews. Thematic analysis was used to identify recurring challenges and assess social work interventions.</div></div><div><h3>Results</h3><div>Among 17 interviewed families, the majority of patients were Black (47.1 %) and male (56.3 %), with a mean age of 9.5 years. Key SDOH challenges included financial strain (62.5 %), caregiver stress (37.5 %), transportation barriers (31.3 %), food insecurity (25 %), and housing instability (12.5 %). Four major themes emerged: insufficient post-discharge support, the value of peer-family connections, the need for coordinated care, and the importance of aerodigestive-specific social work support.</div></div><div><h3>Conclusions</h3><div>Families in pediatric aerodigestive programs face substantial SDOH-related barriers. Strengthening relationship-centered care, enhancing care coordination, and embedding longitudinal, program-specific social work support may improve outcomes and reduce caregiver burden.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112459"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Speech: Parental perspectives on functional outcomes in Mandarin-speaking pediatric cochlear implant users","authors":"Shih-Lung Chen ,&nbsp;Chia-Chen Lin ,&nbsp;Yu-Chien Wang ,&nbsp;Che-Ming Wu","doi":"10.1016/j.ijporl.2025.112456","DOIUrl":"10.1016/j.ijporl.2025.112456","url":null,"abstract":"<div><h3>Purpose</h3><div>This study explored parental perceptions of real-world functional outcomes in Mandarin-speaking children with cochlear implants (CIs), focusing on domains often overlooked by standardized tests, such as communication, social participation, and academic independence.</div></div><div><h3>Method</h3><div>Sixty-three Taiwanese parents completed a culturally adapted Mandarin version of a validated parent-report questionnaire, assessing outcomes across ten functional domains. Children's clinical data including age at implantation, CI duration, speech perception, IQ, and language scores were collected. Spearman correlation analysis was conducted to examine associations between parent-reported outcomes and objective measures.</div></div><div><h3>Results</h3><div>Parents reported high satisfaction in domains such as general functioning and family support, but expressed concern about educational and communication challenges. Expressive language and word recognition scores showed moderate correlations with functional domains, while age at implantation and IQ indices showed weaker or inconsistent associations.</div></div><div><h3>Conclusion</h3><div>Standardized assessments may not fully capture everyday difficulties faced by pediatric CI users, particularly in tonal-language and academic contexts. Parent-report tools offer valuable insights for culturally responsive and family-centered care in Mandarin-speaking populations.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112456"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fistulograms for the management of recurrent and atypical congenital neck anomalies","authors":"Daniel Penaranda ,&nbsp;Jason Qian ,&nbsp;Sukaina Hasnie ,&nbsp;Frederic Bertino ,&nbsp;Bruno Soares ,&nbsp;Hisham M. Dahmoush ,&nbsp;Zahrah Taufique ,&nbsp;Mai Thy Truong","doi":"10.1016/j.ijporl.2025.112457","DOIUrl":"10.1016/j.ijporl.2025.112457","url":null,"abstract":"<div><h3>Background</h3><div>Fistulous and cystic neck lesions that cannot be categorized into traditional classification schemes at presentation are challenging to manage and often manifest as recurrently draining fistulas after primary surgery. Work up with traditional cross-sectional imaging techniques with computed tomography (CT) or magnetic resonance imaging (MRI) may not provide adequate fine details of small channels. Characterization of fistula tracts is necessary for identification and definitive management of atypical or recurrent congenital neck anomalies.</div></div><div><h3>Methods</h3><div>A retrospective review of the electronic medical record from 2 institutions between 2016 and 2023 identifying cases of atypical or recurrent congenital neck anomalies for which CT and MR fistulogram, a novel interventional imaging technique, identified and characterized atypical fistula tracts. Imaging protocol, fistulogram technique, imaging-anatomic correlation, and follow up are reported.</div></div><div><h3>Results</h3><div>We identified 5 patients aged 8–14 years who presented with a draining pit in the head and neck who underwent CT or MRI fistulograms. Diagnoses include first branchial cleft anomalies (n = 3), deep branchial cleft fistula containing ectopic salivary tissue (n = 1), and a recurrent thyroglossal duct cyst (n = 1). Three patients had prior surgery to address these anomalies with recurrences, and one patient had an associated Kabuki syndrome. Complete resection was performed in all cases, with no recurrence to date.</div></div><div><h3>Conclusion</h3><div>CT and MRI fistulograms are minimally invasive, safe, efficacious, and feasible techniques that can be performed before surgery and facilitated on the same day in a single anesthesia encounter. The technique allows for complete visualization of atypical and/or recurrent cystic and fistulous neck anomalies. It facilitates preoperative planning and aids in the characterization of the lesion so that a complete surgical excision can be executed.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"Article 112457"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of infant laryngotracheal reconstruction in tracheostomy decannulation and avoidance","authors":"James A. Leonard ,&nbsp;Daniel L. Blumenthal ,&nbsp;Hengameh K. Behzadpour ,&nbsp;Nancy M. Bauman ,&nbsp;Diego Preciado","doi":"10.1016/j.ijporl.2025.112452","DOIUrl":"10.1016/j.ijporl.2025.112452","url":null,"abstract":"<div><h3>Objective</h3><div>Management of laryngotracheal stenosis in the infant is challenging for patients, families, and providers. This study was designed to evaluate the impact of patient characteristics and surgical techniques on rates of tracheostomy decannulation and avoidance in infants managed with laryngotracheal reconstruction (LTR).</div></div><div><h3>Methods</h3><div>Charts were retrospectively reviewed for all pediatric patients with laryngotracheal stenosis managed with open airway surgery at a tertiary children's hospital between 2008 and 2021. The primary outcome evaluated was tracheostomy decannulation and avoidance.</div></div><div><h3>Results</h3><div>Forty infants were included in the study with a median age of 7.5 months and weight of 6.7 kg. More than half (62.5 %) of the infants were Black or African American. Seventy percent of patients included had grade 3 Myer-Cotton subglottic stenosis. Infants, compared with children (n = 153), were far less likely to have a tracheostomy prior to LTR (22.5 % vs 73.2 %, p &lt; 0.001), undergo double stage surgery (17.5 % vs 51 %, p = 0.001), or use stenting post operatively (7.5 % vs 34.6 %, p = 0.001). Rates of tracheostomy decannulation and avoidance in infants were similar to those in children treated with LTR (82.5 % vs 75.2 %, p = 0.404). In infants, the rate of tracheostomy decannulation and avoidance was far lower in those treated with double stage surgery (OR 0.075, CI 0.01–0.47, p = 0.008), with glottic stenosis (OR 0.103, CI 0.015–0.62, p = 0.015), or multilevel stenosis (OR 0.075, CI 0.01–0.47, p = 0.008).</div></div><div><h3>Conclusion</h3><div>We present a large cohort of infants undergoing LTR for tracheostomy decannulation and avoidance demonstrating efficacy with a reduced chance of success with glottic or multilevel stenosis.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112452"},"PeriodicalIF":1.2,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Follow-up hearing screening for at-risk infants","authors":"Fendi Obuekwe ,&nbsp;Anthony J. Tang ,&nbsp;Zainab A. Balogun ,&nbsp;Amber D. Shaffer ,&nbsp;David H. Chi ,&nbsp;Dennis J. Kitsko","doi":"10.1016/j.ijporl.2025.112454","DOIUrl":"10.1016/j.ijporl.2025.112454","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to determine the percentage of infants with neonatal intensive care unit (NICU) stay &gt;5 days and passed newborn hearing screening (NBHS) who complete recommended audiology follow-up and who have sensorineural hearing loss (SNHL) detected on rescreen by 9 months of age.</div></div><div><h3>Methods</h3><div>A chart review was conducted of patients at a tertiary children's hospital born July 2020 to August 2023. Patients with NICU stay &gt;5 days and completed NBHS were included (n = 929). Patients who missed their NBHS, failed their NBHS, were transferred, or were deceased were excluded (n = 97). Patients who were &lt;12 months of age at time of analysis were also excluded (n = 118).</div></div><div><h3>Results</h3><div>Only 13/714 (1.8 %) presented for audiology follow-up by 9 months of age. Being female (OR: 3.51, 95 % CI: 1.07–11.5), history of ototoxic exposure (OR: 53.9, 95 % CI: 1.38-∞), and Trisomy 21 (OR: 15.5, 95 % CI: 1.45–91.8) were associated with increased odds of follow-up with audiology by 9 months of age. Of the 13 with follow-up, none had SNHL.</div></div><div><h3>Conclusion</h3><div>Infants with NICU stay &gt;5 days and passed NBHS had a low adherence to completing recommended audiology follow-up. SNHL associated with NICU stay was not detected on rescreen. Describing the prevalence of audiology follow-up completion and SNHL detected on rescreen provides further evidence regarding the effectiveness of current screening strategies.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112454"},"PeriodicalIF":1.2,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144549582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of obstructive sleep apnea and related oropharyngeal symptoms in pediatric Ehlers Danlos patients","authors":"Justin Lau ,&nbsp;David C. Kaelber ,&nbsp;Todd D. Otteson","doi":"10.1016/j.ijporl.2025.112460","DOIUrl":"10.1016/j.ijporl.2025.112460","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the prevalence of obstructive sleep apnea (OSA), oropharyngeal symptoms, and surgical OSA treatment in children with Ehlers Danlos syndrome (EDS) compared to control.</div></div><div><h3>Study design</h3><div>Retrospective cohort study.</div></div><div><h3>Setting</h3><div>TriNetX database.</div></div><div><h3>Methods</h3><div>TriNetX was used to query for patients ≤18 years old with and without a diagnosis of EDS. Patients with any recorded occurrence of OSA, oropharyngeal symptoms, and adenotonsillar surgeries were recorded and reported.</div></div><div><h3>Results</h3><div>Among 10104 patients ≤18 years old with EDS, 652 (6.45 %, 95 % CI: 5.99–6.95) had a recorded diagnosis of OSA with a 4.43 (95 % CI: 4.12–4.78) times higher risk of diagnosis compared to a control cohort (n = 17208689). Pediatric EDS patients also had a higher risk of dysphagia and dysphonia at 5.91 (95 % CI: 5.51–6.33) and 2.90 (95 % CI: 2.24–3.76), respectively. Additionally, children with EDS were more likely to undergo an adenotonsillectomy compared to control (2.51, 95 % CI: 2.23–2.82).</div></div><div><h3>Conclusion</h3><div>Children with EDS are at a higher risk of developing OSA and other oropharyngeal symptoms like dysphagia and dysphonia. These patients are also more likely to undergo adenotonsillar surgeries as a first-line approach to correcting obstructive sleep apnea. Otolaryngologists and speech language pathologists can play a major beneficial role in working with pediatric EDS patients in the management and treatment of oropharyngeal symptoms.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112460"},"PeriodicalIF":1.2,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upsizing tracheostomies: Impacts on respiratory support needs in a vulnerable population","authors":"Emily Cushing ,&nbsp;Jemma Maynard ,&nbsp;Isaac Kistler ,&nbsp;Aidan Vanek ,&nbsp;Makanko Komara ,&nbsp;Alexandra Gach ,&nbsp;Prasanth Pattisapu ,&nbsp;Amy Manning","doi":"10.1016/j.ijporl.2025.112437","DOIUrl":"10.1016/j.ijporl.2025.112437","url":null,"abstract":"<div><h3>Background</h3><div><em>Objective(s)</em>: Proper tracheostomy tube position is crucial in pediatric patients to reduce decannulation and ensure adequate ventilation. Little research exists on optimal tracheostomy length and its impact on ventilation. This study aimed to examine changes in FiO2, with a secondary focus on PEEP, albuterol and bagging associated with increasing tracheostomy length.</div></div><div><h3>Methods</h3><div>This is an IRB-approved single-institution case series retrospective review of patients under 2 who received a tracheostomy upsize between 2018 and 2022. Data collected includes demographics, comorbidities, tracheostomy details, and FiO2 prior and following upsize. Interrupted time-series segmented linear models assessed differences in FiO2 and PEEP. Albuterol administration and bagging events were included as binary measures. Albuterol use is summarized using percentages and bagging visualized on a bar chart.</div></div><div><h3>Results</h3><div>A total of 118 patients underwent tracheostomy, and 71 (52 % male, 48 % female) underwent at least one upsizing at a median of 1.55 months post initial placement. These 71 patients received the first upsize, 32 patients received a second upsize, and 11 patients received a third upsize. FiO2 levels were not found to be different after upsizes 1 and 2 (beta:0.43(95 %CI: 1.7,2.6); beta:0.85(95 %CI: 1.9,3.6)). FiO2 was higher after upsize 3 (beta:5.2(95 %CI: 1.7,8.6)). Analysis of PEEP, albuterol, and bagging was limited due inconsistent documentation.</div></div><div><h3>Conclusion</h3><div>This study provides insight into the changing respiratory parameters, mainly FiO2, associated with tracheostomy upsize. The higher FiO2 requirements after the third upsize indicates this subgroup of patients have greater respiratory support needs and further increasing the tracheostomy length may be of limited benefit.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112437"},"PeriodicalIF":1.2,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and safety of intranasal corticosteroids for adenoid Hypertrophy: A systematic review and meta-analysis","authors":"Abdulsalam Alqutub ,&nbsp;Sarah F. Mozahim ,&nbsp;Naif F. Mozahim ,&nbsp;Osama A. Alsulami ,&nbsp;Sarah M. AlSharif ,&nbsp;Abeer Z. Malebari ,&nbsp;Talal Al-Khatib","doi":"10.1016/j.ijporl.2025.112450","DOIUrl":"10.1016/j.ijporl.2025.112450","url":null,"abstract":"<div><h3>Background</h3><div>Adenoid hypertrophy is a common condition that can lead to significant symptoms and possibly complications. Intranasal corticosteroids have emerged as a promising non-surgical treatment for this condition. Our study aims to evaluate the effectiveness and safety of intranasal corticosteroids in managing it.</div></div><div><h3>Methods</h3><div>From inception to November 2024, we conducted a thorough search across four electronic databases. Our study included all available research comparing intranasal corticosteroids to any comparator in managing adenoid hypertrophy. The study's outcomes were the rate of adenoidectomy, post-treatment clinical symptoms scores, adenoid hypertrophy grade, adenoid size, and adverse effects. The categorical variables were pooled as risk ratios (RR). Continuous outcomes were pooled using the standardized mean differences (SMD) with a 95 % confidence interval (CI).</div></div><div><h3>Results</h3><div>Thirty studies involving 2301 children with adenoid hypertrophy were included in our analysis. Our pooled results showed a lower rate of adenoidectomy in patients treated with intranasal corticosteroids compared to the control group (RR = 0.30, 95 % CI [0.17 to 0.54], P &lt; 0.0001). The intranasal corticosteroids group also exhibited a significantly lower overall clinical symptoms score (SMD = −0.81, 95 % CI [-1.01 to −0.60], P &lt; 0.00001) and smaller adenoid size (SMD = −1.33, 95 % CI, [-1.91 to −0.75], P &lt; 0.00001).</div></div><div><h3>Conclusion</h3><div>Intranasal corticosteroids are effective for treating adenoid hypertrophy, as they reduce adenoid size, improve clinical symptoms, and decrease the need for adenoidectomy. Clinicians should incorporate intranasal corticosteroids into treatment regimens to alleviate clinical symptoms and potentially avoid surgery. To support our results, further large-scale randomized controlled trials with extended follow-up periods are recommended.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112450"},"PeriodicalIF":1.2,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical management and outcome of Meniere’s disease in children and adolescents: A systematic review","authors":"Jeyasakthy Saniasiaya,&nbsp;Narayanan Prepageran","doi":"10.1016/j.ijporl.2025.112449","DOIUrl":"10.1016/j.ijporl.2025.112449","url":null,"abstract":"<div><h3>Introduction</h3><div>Meniere's disease (MD), or idiopathic endolymphatic hydrops, has been well-established in adults. However, due to the lack of understanding of pathomechanism and the progression of MD in children, managing this condition remains a challenge. The review aims to investigate the clinical management and outcome of treatments in children and adolescents with MD.</div></div><div><h3>Methods</h3><div>A systematic literature review was conducted in accordance with PRISMA guidelines to identify articles that assessed the outcome of treatment among children with MD. Information regarding the child's demographic data, MD symptoms, investigations, treatment, and outcomes was extracted from the included studies. The primary outcome was defined as the success of treatment based on the resolution or improvements of symptoms, while the secondary outcome was determined by recurrence or worsening symptoms or the presence of complications.</div></div><div><h3>Results</h3><div>The review included 12 studies published between 1958 and 2024. Fifty-seven children were noted, with a mean age of 9.9 ± 3.1 (range 5–14 years) and female predominance (60 %). Most of the included articles were from Asian countries (66.6 %), followed by Europe (16.7 %) and the USA (16.7 %). Improvement of symptoms was reported in 91.7 % of the included studies, with recurrence reported in four studies and persistence in symptoms found in one study. Diuretics were the most favoured intervention. Endolymphatic sac decompression is the favoured surgical option. Complications reported include worsening hearing found in two children (3.5 %).</div></div><div><h3>Conclusion</h3><div>Pharmacological and surgical treatment results in good outcomes in children with MD. However, the quality of the evidence is inadequate to recommend the ideal intervention until a better-quality study has been completed. Future randomised controlled studies with a large sample size are warranted to determine the ideal intervention in children with MD.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112449"},"PeriodicalIF":1.2,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between ankyloglossia and pediatric obstructive sleep apnea: A retrospective cohort study using a global health network","authors":"Carlos O'Connor-Reina ,&nbsp;Prof David Gozal ,&nbsp;Maria Teresa Garcia Iriarte ,&nbsp;Laura Rodriguez Alcala ,&nbsp;Eduardo Correa ,&nbsp;Gema Hernandez Ibarburu ,&nbsp;Prof David Perez del Rey ,&nbsp;Peter Baptista ,&nbsp;Prof Guillermo Plaza","doi":"10.1016/j.ijporl.2025.112447","DOIUrl":"10.1016/j.ijporl.2025.112447","url":null,"abstract":"<div><h3>Objective</h3><div>Pediatric obstructive sleep apnea (OSA) affects an estimated 1–3 % of children, corresponding to over 40 million cases globally. While obesity and adenotonsillar hypertrophy are well-established pediatric risk factors, the potential role of ankyloglossia remains underexplored. We evaluated whether a diagnosis of ankyloglossia is associated with an increased risk of developing OSA in children.</div></div><div><h3>Methods</h3><div>Retrospective cohort study of 3,535,879 pediatric patients from the TriNetX Global Collaborative Network (143 healthcare organizations). Two cohorts were defined based on the presence or absence of an ankyloglossia diagnosis and the subsequent development of OSA over a follow-up period of up to 10 years. Propensity score matching controlled for confounders. Kaplan-Meier survival analysis and log-rank testing assessed OSA-free survival.</div></div><div><h3>Results</h3><div>Among the 37,640 children who developed OSA during follow-up (62.2 % male; mean age 2.8 ± 3.6 years), those in the ankyloglossia group were diagnosed at an earlier age (median 1525 vs. 1877 days). The rate of OSA diagnosis was higher in the ankyloglossia group: 6.1 % vs. 4.0 % (risk difference 2.1 %, 95 % CI: 1.8–2.4; RR: 1.53; OR: 1.56; <em>P</em> &lt; 0.001) These values reflect outcomes from the propensity score–matched cohorts. Frenotomy did not significantly impact OSA survival probability.</div></div><div><h3>Conclusion</h3><div>The diagnosis of ankyloglossia is associated with increased and earlier pediatric OSA risk. Frenotomy, as captured in this dataset, was not associated with a lower risk. These findings do not support or exclude a therapeutic role for frenotomy and highlight the need for further prospective research.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"195 ","pages":"Article 112447"},"PeriodicalIF":1.2,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}