Chelsea Cleveland, Jamil Hayden, Tekin Baglam, Todd Otteson
{"title":"Characterization of hearing loss in pediatric patients with osteogenesis imperfecta","authors":"Chelsea Cleveland, Jamil Hayden, Tekin Baglam, Todd Otteson","doi":"10.1016/j.ijporl.2024.112027","DOIUrl":"10.1016/j.ijporl.2024.112027","url":null,"abstract":"<div><h3>Introduction</h3><p>Osteogenesis imperfecta (OI) is a common heritable disorder affecting type 1 collagen. The sequelae of OI vary, but hearing loss is a significant complication with 46–58 % of patients having some degree of hearing loss. Previous studies have suggested patients with OI may have conductive, sensorineural, or mixed hearing loss. Majority of these studies focus on the adult population.</p></div><div><h3>Objectives</h3><p>Identify a relationship between OI and hearing loss in the pediatric population.</p></div><div><h3>Methods</h3><p>The TriNetx Analytics Network, a federated health research network that aggregates the de-identified electronic health record data of over 78 million patients across the United States, was queried for patients 18 years old or younger with a diagnosis of OI. Patients in this group with diagnosis of sensorineural, conductive, or mixed hearing loss were recorded. Patients with diagnoses of congenital cytomegalovirus, congenital inner ear malformations, and noise-induced hearing loss were excluded from analysis.</p></div><div><h3>Results</h3><p>Out of 3256 patients 18 years old or younger with OI, 10.07 % (95 % CI: 9.06–11.16) had a history of any form of hearing loss, 5.71 % (95 % CI: 4.94–6.57) had conductive hearing loss, 3.01 % (95 % CI: 2.45–3.66) had sensorineural hearing loss, and 1.35 % (95 % CI: 0.98–1.81) had mixed hearing loss. Relative risks for diagnosis of any type of hearing loss, conductive hearing loss, sensorineural hearing loss, and mixed hearing loss were calculated: 5.90 (95 % CI 5.32–6.53), 5.08 (95 % CI 4.42–5.84), 6.18 (95 % CI 5.09–7.51), and 13.86 (95 % CI 10.33–18.59) respectively.</p></div><div><h3>Discussion</h3><p>This study is the largest to date that describes a relationship between OI and conductive, sensorineural, and mixed hearing loss. Pediatric patients with OI are almost five times as likely to have any type of hearing loss. There was a significant increased risk in each subgroup, but conductive hearing loss was the most common for hearing loss in children with OI. The highest risk subtype when compared to controls was mixed hearing loss.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kung-Ting Kao , Margaret Zacharin , Stephen Farrell , Peter Simm
{"title":"Clinical protocol using calcium and calcitriol after paediatric total thyroidectomy decreases postoperative hypocalcaemia and inpatient blood tests","authors":"Kung-Ting Kao , Margaret Zacharin , Stephen Farrell , Peter Simm","doi":"10.1016/j.ijporl.2024.112021","DOIUrl":"https://doi.org/10.1016/j.ijporl.2024.112021","url":null,"abstract":"<div><h3>Introduction</h3><p>Postoperative hypocalcaemia is common after thyroidectomy. This study aimed to evaluate whether a standardised post-thyroidectomy protocol using prophylactic calcium and calcitriol reduces hypocalcaemia incidence after total thyroidectomy in children and adolescents.</p></div><div><h3>Methods</h3><p>A cohort children and adolescents ≤18 years of age undergoing total thyroidectomy between January 2016 and October 2022 in one institution were retrospectively identified and divided into pre-protocol and post-protocol groups. The primary outcome measure was hypocalcaemia (total serum calcium of <2.0 mmol/L; ionised serum calcium of 0.9 mmol/L). Secondary outcome measures were the occurrence of hypercalcaemia (serum Calcium >2.7 mmol/L; ionised calcium >1.31 mmol/L), length of hospitalisation and number of postoperative blood tests.</p></div><div><h3>Results</h3><p>There were 22 patients in each group (mean age 11.8; SD 4.3 years, female 36 %). The rate of hypocalcaemia was significantly higher in the pre-protocol group than the post-protocol group (54 % vs 13.6 %, p = 0.010). Patients in the pre-protocol group had more inpatient blood tests (mean 5.4; SD 3.2) than the post-protocol group (mean 3.3; SD 1.8, p = 0.011), although the total postoperative blood test count was similar between the groups. Six (13.6 %) patients developed hypercalcaemia. The rate of hypercalcaemia was similar between groups (pre-protocol 2, 9.1 %; post-protocol 4, 18.1 %; p = 0.664). Length of hospitalisation was similar between groups.</p></div><div><h3>Conclusion</h3><p>Our standardized protocol decreased hypocalcemia and inpatient blood tests after total thyroidectomy in children. Future research should explore if incorporating preoperative calcium and calcitriol treatment, along with intraoperative PTH levels for risk management, can further reduce hypocalcemia rates in paediatric patients.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monique Robinson , David Burgner , Ashleigh Lin , Peter Jacoby , Robert Eikelboom , Shyan Vijayasekaran , Christopher G. Brennan-Jones
{"title":"Risk of otitis media in offspring following maternal prenatal stress exposure","authors":"Monique Robinson , David Burgner , Ashleigh Lin , Peter Jacoby , Robert Eikelboom , Shyan Vijayasekaran , Christopher G. Brennan-Jones","doi":"10.1016/j.ijporl.2024.112022","DOIUrl":"10.1016/j.ijporl.2024.112022","url":null,"abstract":"<div><h3>Objectives</h3><p>There is limited but consistent evidence that suggests prenatal factors, including maternal stress, may contribute to susceptibility for otitis media. We aimed to determine the effect of multiple life stress events during pregnancy on risk of acute and recurrent otitis media in offspring at three and five years of age.</p></div><div><h3>Methods</h3><p>Exposure data on stressful life events were collected from pregnant women in a longitudinal prospective pregnancy cohort study, at 18 and 34 weeks’ gestation. We used longitudinal regression models stratified by offspring sex to examine associations between the number, type and timing of maternal prenatal stress events and the likelihood of any OM in addition to recurrent OM infection at age three and five years, adjusting for pre-specified prenatal sociodemographic and environmental confounders.</p></div><div><h3>Results</h3><p>Each additional stressful life event in pregnancy was associated with increased risk of any OM at both ages (3 years: OR = 1.07, 95%CI = 1.02, 1.12; 5 years: OR = 1.07, 95%CI = 1.02, 1.12), with larger effect sizes for recurrent otitis media (3 years: OR = 1.11, 95%CI = 1.05, 1.17; 5 years: OR = 1.09, 95%CI = 1.04, 1.14). Risk of offspring otitis media did not differ with timing of stress nor by offspring sex. Specific types of stress (pregnancy and relationship problems, issues with other children) were each associated with increased risk of recurrent OM at age three and five years.</p></div><div><h3>Conclusions</h3><p>We observed a dose-response relationship between maternal stressful life events in pregnancy and the risk for offspring otitis media in the preschool years, most marked for recurrent otitis media.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141467970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A retrospective analysis of factors affecting speech production in school-aged children with cleft palate (+- cleft lip)","authors":"Hedieh Hashemi Hosseinabad , Yixun Xing , Monica Kemp","doi":"10.1016/j.ijporl.2024.112029","DOIUrl":"10.1016/j.ijporl.2024.112029","url":null,"abstract":"<div><h3>Objective</h3><p>The present investigation examined how factors such as cleft type, age of primary palatal surgery, diagnosed syndromes, hearing problems, and malocclusions could predict persistent speech difficulties and the need for speech services in school-aged children with cleft palate.</p></div><div><h3>Methods</h3><p>Participants included 100 school-aged children with cleft palate. Americleft speech protocol was used to assess the perceptual aspects of speech production. The logistic regression was performed to evaluate the impact of independent variables (IV) on the dependent variables (DV): intelligibility, posterior oral CSCs, audible nasal emission, hypernasality, anterior oral CSCs, and speech therapy required.</p></div><div><h3>Results</h3><p>Sixty-five percent of the children were enrolled in (or had received) speech therapy. The logistic regression model shows a good fit to the data for the need for speech therapy (Hosmer and Lemeshow's <span><math><mrow><msup><mi>χ</mi><mn>2</mn></msup><mrow><mo>(</mo><mn>8</mn><mo>)</mo></mrow><mo>=</mo><mn>9.647</mn><mo>,</mo><mi>p</mi><mo>=</mo><mo>.</mo><mn>291</mn></mrow></math></span>). No IVs were found to have a significant impact on the need for speech therapy. A diagnosed syndrome was associated with poorer intelligibility (Pulkstenis-Robinson's <span><math><mrow><msup><mi>χ</mi><mn>2</mn></msup><mrow><mo>(</mo><mn>11</mn><mo>)</mo></mrow><mo>=</mo><mn>7.120</mn><mo>,</mo><mi>p</mi><mo>=</mo><mo>.</mo><mn>789</mn></mrow></math></span>). Children with diagnosed syndromes have about six times the odds of a higher hypernasality rating (Odds Ratio = 5.703) than others. The cleft type was significantly associated with audible nasal emission (<span><math><mrow><mtext>Fisher</mtext><mo>’</mo><mi>s</mi><mspace></mspace><mtext>exact</mtext><mspace></mspace><mi>p</mi><mo>=</mo><mo>.</mo><mn>006</mn></mrow></math></span>). At the same time, malocclusion had a significant association with anterior oral CSCs (<span><math><mrow><mtext>Fisher</mtext><mo>’</mo><mi>s</mi><mspace></mspace><mtext>exact</mtext><mspace></mspace><mi>p</mi><mo>=</mo><mo>.</mo><mn>005</mn></mrow></math></span>).</p></div><div><h3>Conclusions</h3><p>According to the latest data in the Cleft Registry and Audit Network Annual Report for the UK, the majority of children with cleft palate attain typical speech by age five. However, it is crucial to delve into the factors that may influence the continuation of speech disorders beyond this age. This understanding is vital for formulating intervention strategies aimed at mitigating the long-term effects of speech disorders as individuals grow older.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lexical tone recognition in multi-talker babbles and steady-state noise by Mandarin-speaking children with unilateral cochlear implants or bimodal hearing","authors":"Chao Meng , Qianqian Guo , Jing Lyu , Abigail Jaquish , Xueqing Chen , Li Xu","doi":"10.1016/j.ijporl.2024.112020","DOIUrl":"10.1016/j.ijporl.2024.112020","url":null,"abstract":"<div><h3>Background and objectives</h3><p>Lexical tone presents challenges to cochlear implant (CI) users especially in noise conditions. Bimodal hearing utilizes residual acoustic hearing in the contralateral side and may offer benefits for tone recognition in noise. The purpose of the present study was to evaluate tone recognition in both steady-state noise and multi-talker babbles by the prelingually-deafened, Mandarin-speaking children with unilateral CIs or bimodal hearing.</p></div><div><h3>Methods</h3><p>Fifty-three prelingually-deafened, Mandarin-speaking children who received CIs participated in this study. Twenty-two of them were unilateral CI users and 31 wore a hearing aid (HA) in the contralateral ear (i.e., bimodal hearing). All subjects were tested for Mandarin tone recognition in quiet and in two types of maskers: speech-spectrum-shaped noise (SSN) and two-talker babbles (TTB) at four signal-to-noise ratios (−6, 0, +6, and +12 dB).</p></div><div><h3>Results</h3><p>While no differences existed in tone recognition in quiet between the two groups, the Bimodal group outperformed the Unilateral CI group under noise conditions. The differences between the two groups were significant at SNRs of 0, +6, and +12 dB in the SSN conditions (all <em>p</em> < 0.05), and at SNRs of +6 and +12 dB of TTB conditions (both <em>p</em> < 0.01), but not significant at other conditions (<em>p</em> > 0.05). The TTB exerted a greater masking effect than the SSN for tone recognition in the Unilateral CI group as well as in the Bimodal group at all SNRs tested (all <em>p</em> < 0.05). Among demographic or audiometric variables, only age at implantation showed a weak but significant correlation with the mean tone recognition performance under the SSN conditions (<em>r</em> = −0.276, <em>p</em> = 0.045). However, when Bonferroni correction was applied to the correlation analysis results, the weak correlation became not significant.</p></div><div><h3>Conclusion</h3><p>Prelingually-deafened children with CIs face challenges in tone perception in noisy environments, especially when the noise is fluctuating in amplitude such as the multi-talker babbles. Wearing a HA on the contralateral side when residual hearing permits is beneficial for tone recognition in noise.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141534434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Hoying , Sindhoosha Malay , Matthew Gropler , Todd Otteson
{"title":"Epidemiological assessment of non-tuberculous mycobacterial cervicofacial lymphadenitis: A PHIS database study","authors":"David Hoying , Sindhoosha Malay , Matthew Gropler , Todd Otteson","doi":"10.1016/j.ijporl.2024.112019","DOIUrl":"10.1016/j.ijporl.2024.112019","url":null,"abstract":"<div><h3>Objective</h3><p>Cervicofacial lymphadenitis caused by non-tubercular mycobacterial (NTM) infections has the highest infection rate in children. Our objective was to assess patient demographics, treatment methods, and the impact of weather and geography on the incidence of disease in patients with NTM cervicofacial lymphadenitis.</p></div><div><h3>Methods</h3><p>The Pediatric Health Information System (PHIS) database was queried for data on all patients diagnosed with concurrent cervicofacial lymphadenopathy and NTM infection from 2004 to 2022. We assessed the association between weather patterns and NTM cervicofacial lymphadenitis by collecting monthly weather data from the NOAA National Center for Environmental Information. Incidence rates were calculated by dividing the number of cases by the total hospital discharges during the study period.</p></div><div><h3>Results</h3><p>Among 47 PHIS hospitals, there were 992 diagnoses of NTM cervicofacial lymphadenitis. The average age at diagnosis was 2 [IQR, 2–4], with 59 % female. Drainage of skin abscesses or lesions was performed for 93 (9.4 %) patients, while 15 (1.5 %) had an excisional procedure of the CPT codes assessed. The most common antibiotics utilized were cephalosporins (28 %), macrolides (27 %), and rifampin (12 %). The most common treatment method was surgery with antibiotics (37 %) followed by no treatment at all (35 %), surgery alone (17 %), and antibiotics alone (10 %). Of the 28 states included in the analysis, Washington (IR: 3.5) and Nebraska (IR: 3.3) had the highest incidence rates (IR) of NTM cervical lymphadenitis. The cases were relatively equally distributed across the different weather seasons within each U.S. geographic region. However, the overall average wind speed was weakly associated with increasing the risk of diagnosis when utilizing a mixed effect zero-inflated negative binomial model (Incidence Ratio: 1.07, 95 % CI: (1.01–1.14), p = 0.035).</p></div><div><h3>Conclusions</h3><p>Our results indicate that the most common treatment method utilized in patients within our cohort with NTM cervicofacial lymphadenitis was the concurrent use of surgery and antibiotics. Our results also indicate there may be variation in the incidence rate among different states, but additional studies are needed as our cohort only included approximately 50 % of states within the U.S.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141467969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan Ruiz , Christopher Wootten , Karthik Balakrishnan , Richard Paul Boesch , Jeremy Prager , Rachel Rosen , Douglas Sidell , Alessandro de Alarcon , Eric H. Chiou , Michael J. Rutter , Joseph Piccione , Aerodigestive Research Collaborative
{"title":"Consensus on intake questionnaire data elements in the development of an aerodigestive registry","authors":"Ryan Ruiz , Christopher Wootten , Karthik Balakrishnan , Richard Paul Boesch , Jeremy Prager , Rachel Rosen , Douglas Sidell , Alessandro de Alarcon , Eric H. Chiou , Michael J. Rutter , Joseph Piccione , Aerodigestive Research Collaborative","doi":"10.1016/j.ijporl.2024.112016","DOIUrl":"10.1016/j.ijporl.2024.112016","url":null,"abstract":"<div><h3>Objective</h3><p>To define the essential elements of the intake questionnaire that will be a part of a larger multicenter registry for aerodigestive patients.</p></div><div><h3>Methods</h3><p>A modified Delphi method was utilized to obtain consensus on the data elements that should warrant inclusion in the final research database. Patient questionnaires from the eight participating institutions were reviewed and individual elements were aggregated into 14 categories.</p></div><div><h3>Results</h3><p>A total of 198 initial elements were voted on for inclusion. The categories included demographics, respiratory symptoms, gastrointestinal symptoms, ear nose and throat symptoms, feeding, birth history, medical history, surgical history, family history, social history, medications prior to evaluation, devices used prior to evaluation, prior diagnostic evaluations, and prior evaluation by aerodigestive team members. 83 of the 198 elements met consensus for inclusion in the final registry for an inclusion rate of 41.9 %. Three separate rounds of ranking were required to obtain consensus.</p></div><div><h3>Conclusion</h3><p>The aerodigestive registry is an important initiative that will help foster research and help guide future management. The intake questionnaire of the registry is a critical component of this project, and the consensus obtained during this study should help create a streamlined and efficient registry that will help all aerodigestive patients on a national level.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141407350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Micah K. Harris , Nathan Lu , Anthony Tang , Natasha Mayer , Elizabeth B. McCarty , Amanda Stapleton , Noel Jabbour
{"title":"A qualitative analysis of pediatric otolaryngology fellowship websites","authors":"Micah K. Harris , Nathan Lu , Anthony Tang , Natasha Mayer , Elizabeth B. McCarty , Amanda Stapleton , Noel Jabbour","doi":"10.1016/j.ijporl.2024.112026","DOIUrl":"10.1016/j.ijporl.2024.112026","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the availability and breadth of information provided by program-created pediatric otolaryngology fellowship websites as well as the American Society of Pediatric Otolaryngology (ASPO) program directory.</p></div><div><h3>Methods</h3><p>Program-created pediatric otolaryngology fellowship websites and the ASPO directory were evaluated for 16 key criteria deemed to be relevant to fellowship applicants.</p></div><div><h3>Results</h3><p>All 36 ACGME-accredited pediatric otolaryngology fellowship programs had websites that were readily available by Google search, and the ASPO program directory contained direct links to 17 (47.2 %) program-created websites. On average, program-created websites fulfilled 6.9 (43.1 %, range 1–11) and the ASPO directory fulfilled 6.9 (43.1 %, range 3–11) of the 16 key criteria. When utilizing both resources, the average increased to 8.3 (51.2 %) - criteria included program description (94.4 %), location description (30.4 %), fellowship director contact information (94.4 %), program coordinator contact information (72.2 %), teaching responsibilities (68.6 %), call responsibilities/schedule (41.7 %), operative volume (80 %), breadth of surgical exposure (94.4 %), research opportunities (72.2 %), research expectations (63.9 %), current fellow(s) (42.9 %), post-fellowship placement (28.6 %), fellow clinic (28.6 %), medical missions/outreach (20 %), and resident coverage (36.1 %).</p></div><div><h3>Conclusion</h3><p>Pediatric otolaryngology fellowship websites as well as program-specific data sheets from ASPO lack many key criteria that would otherwise be valuable to applicants. Inclusion of these criteria could help applicants make a more well-informed decision when applying into pediatric otolaryngology fellowship.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mackenzie O'Donnell , Nasrin Sultana , Nasreen Talib , Jason May , Michael Slogic
{"title":"The use of hearing tests to assess otitis media with effusion in children with Down syndrome","authors":"Mackenzie O'Donnell , Nasrin Sultana , Nasreen Talib , Jason May , Michael Slogic","doi":"10.1016/j.ijporl.2024.112018","DOIUrl":"10.1016/j.ijporl.2024.112018","url":null,"abstract":"<div><h3>Background</h3><p>Down syndrome is associated with an increased risk for otitis media with effusion (OME), a childhood condition in which fluid accumulates in the middle ear, potentially leading to hearing loss. The American Academy of Pediatrics Down syndrome guidelines and the American Academy of Otolaryngology – Head and Neck Surgery OME guidelines recommend hearing testing to assess the hearing status of children with Down syndrome diagnosed with OME.</p></div><div><h3>Methods</h3><p>Through an Institutional Review Board approved retrospective chart review at Children's Mercy, this project assessed how clinical factors affect the frequency in which children with Down syndrome receive hearing testing after diagnosis of OME. The study included data from all children with Down syndrome between 1 and 8 years old diagnosed with OME in the Down syndrome, general pediatrics, and otolaryngology clinics between 2018 and 2020. Demographics and clinical factors, including clinic setting, were collected.</p></div><div><h3>Results</h3><p>Of the 124 patients identified, 91.1 % were diagnosed with OME in the otolaryngology clinic and 33.1 % received hearing testing. While most diagnoses occurred in the otolaryngology clinic, a higher proportion of hearing testing at the time of diagnosis occurred in the Down syndrome clinic. This could be explained by the fact that the Down syndrome clinic is a multidisciplinary clinic, where yearly visits include hearing screening. Bivariate analysis using chi-square or Fisher's tests showed that clinic setting had a significant association (p-value <0.001) with hearing testing. However, logistic regression depicted all clinical factors had an insignificant effect on hearing testing at 5 % significance.</p></div><div><h3>Conclusion</h3><p>While results indicate hearing testing is largely not performed to assess OME early in otolaryngology clinics, they may be used to assess intervention efficacy post-diagnosis. Results point to the importance of Down syndrome clinics in early diagnosis of hearing loss leading to timely referrals to otolaryngology clinics which diagnose and manage OME in children with Down syndrome.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165587624001721/pdfft?md5=f4a2b7b394ad23c1d28d21a6c946fc50&pid=1-s2.0-S0165587624001721-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141534395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danuta Raj-Koziak , Elżbieta Gos , Marek Porowski , Piotr Henryk Skarzynski , Henryk Skarzynski
{"title":"Children's Tinnitus Questionnaire – A novel tool for assessing the impact of tinnitus on a child's everyday life","authors":"Danuta Raj-Koziak , Elżbieta Gos , Marek Porowski , Piotr Henryk Skarzynski , Henryk Skarzynski","doi":"10.1016/j.ijporl.2024.112024","DOIUrl":"10.1016/j.ijporl.2024.112024","url":null,"abstract":"<div><h3>Objective</h3><p>Self-report instruments are commonly used in tinnitus clinics, but they are presently available only for adults. There is a lack of a validated multi-item instrument to capture tinnitus-related problems in children and their impact on everyday life. This study has developed and validated a specifically child-centered questionnaire to assess the impact of tinnitus.</p></div><div><h3>Methods</h3><p>Development of the tool consisted of several stages. Following a pilot study on 12 children with tinnitus, a validation study was done on a further 192 children with tinnitus aged between 11 and 14 years. The children had an audiological examination, completed a Visual Analogue Scale (VAS) and the newly framed questionnaire.</p></div><div><h3>Results</h3><p>The development and validation process resulted in the new 11-item Children's Tinnitus Questionnaire (CTQ). It includes items concerning the impact of tinnitus on functional, cognitive, emotional and social domains. The validity of the new tool has been established by finding significant correlations between it and VAS loudness (<em>r</em> = 0.42), VAS annoyance (<em>r</em> = 0.67), and VAS coping (<em>r</em> = −0.41). Validity has also been confirmed by measuring differences in CTQ scores and 4 groups of children having graded incidences of tinnitus. The internal consistency assessed with Cronbach's alpha was high (<em>α</em> = 0.82).</p></div><div><h3>Conclusion</h3><p>The Children's Tinnitus Questionnaire (CTQ) is the first fully validated multi-item instrument designed specifically for children. The tool has the potential to become a valuable new instrument for use in clinical practice and research; it might be useful for assessing the impact of tinnitus on those children who find that the condition creates problems in their everyday life.</p></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165587624001782/pdfft?md5=4e44e606573c489233539380f8c0a4ae&pid=1-s2.0-S0165587624001782-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}