International journal of pediatric otorhinolaryngology最新文献

{"title":"Short-acting versus long-acting tympanostomy tubes in the paediatric population: a systematic review and meta-analysis of duration in-situ and complications.","authors":"Joyce Ho, Elizabeth Kim, Rithvik Reddy, Marlene Soma","doi":"10.1016/j.ijporl.2026.113063","DOIUrl":"https://doi.org/10.1016/j.ijporl.2026.113063","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"211 ","pages":"113063"},"PeriodicalIF":1.6,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation and early outcomes of AI-powered ambient documentation in pediatric otolaryngology practice.","authors":"Perla Villamor, Amirbahador Golchin, Aydin Zahedivash, Alan G Cheng, Grace S Kim, Kara Meister","doi":"10.1016/j.ijporl.2026.113049","DOIUrl":"https://doi.org/10.1016/j.ijporl.2026.113049","url":null,"abstract":"<p><strong>Background: </strong>Electronic health record (EHR) documentation contributes to clinician burnout, yet evidence on ambient artificial intelligence (AI) scribes in pediatric surgical subspecialties is limited. We evaluated adoption and documentation efficiency after implementing an ambient AI scribe in pediatric otolaryngology.</p><p><strong>Methods: </strong>In this retrospective quality-improvement study at a tertiary academic pediatric otolaryngology practice, an ambient AI scribe was introduced in March 2025. We analyzed initial rollout and a current-state window (January-July 2026), after early effects had stabilized, comprising 16 clinicians (12 physicians, 4 advanced practice providers [APPs]). Adoption and documentation time were derived from EHR efficiency dashboards for AI-assisted versus manual encounters. Utilization was compared by visit type and clinician role using chi-square tests and Cochran-Mantel-Haenszel analysis stratified by clinician.</p><p><strong>Results: </strong>Practice-wide utilization rose from 17.6% of 1690 encounters at rollout to 39.2% the following quarter, and remained 39.9% of 11,565 encounters 10 months later. Adoption was bimodal (6 clinicians ≥50% of encounters; 5 < 10%). Utilization was higher among physicians than APPs (47.7% vs 10.9%; P < 0.001) and in new-patient than established visits (47.0% vs 34.7%; P < 0.001), persisting in clinician-stratified analysis (odds ratio 2.56; P < 0.001). All 16 clinicians remained in the same utilization tier throughout. Median note-editing time was lower with AI assistance (∼4.0 vs 11.8 min), while median note length was similar (∼4000 characters).</p><p><strong>Conclusions: </strong>Ambient AI scribe implementation was associated with rapid adoption sustained at both practice and individual clinician levels, and with reduced documentation time without increased note length, with particular value for clinicians lacking documentation support.</p>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"211 ","pages":"113049"},"PeriodicalIF":1.6,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocolized tranexamic acid use lowers surgical intervention rates after active post-tonsillectomy hemorrhage: A retrospective cohort study.","authors":"Spencer H Short, Trevor Pharr, Minahil Chaudhry, Joshua D Madera, Sri K Chennupati","doi":"10.1016/j.ijporl.2026.113057","DOIUrl":"https://doi.org/10.1016/j.ijporl.2026.113057","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether a standardized tranexamic acid (TXA) protocol was associated with reduced operative intervention among patients with active post-tonsillectomy hemorrhage (PTH).</p><p><strong>Methods: </strong>This retrospective cohort study included patients aged 2 to 21 years with documented active PTH evaluated at a tertiary pediatric otolaryngology service from January 1, 2021, to July 31, 2025. Of 5342 tonsillectomies, 246 patients returned with suspected PTH and 116 met inclusion criteria for active bleeding or clot. A TXA protocol was implemented July 25, 2024. The primary outcome was operative intervention for hemorrhage control. Associations between TXA use, protocol era, route, and operative intervention were analyzed.</p><p><strong>Results: </strong>Among 116 included patients, operative intervention decreased from 63% before protocol implementation to 40% after implementation (OR 2.50; 95% CI 1.18-5.25; p = .02). Overall, 27 of 30 patients (90%) who did not receive TXA required operative intervention, compared with 33 of 86 patients (38%) who received TXA (OR 0.07; 95% CI 0.02-0.25; p < .001). In adjusted analysis, TXA route was significantly associated with operative intervention (p < .001). Compared with no TXA, nebulized, intravenous, and combined nebulized/intravenous TXA were each associated with lower adjusted odds of operative intervention; stratified analyses suggested nebulized TXA was the most consistent driver.</p><p><strong>Conclusion: </strong>Protocolized TXA use was associated with reduced operative intervention in children and young adults with active PTH, with nebulized TXA showing the strongest association with avoidance of return to the operating room. The study was limited by its retrospective design and utilization of data from a single tertiary center.</p>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"211 ","pages":"113057"},"PeriodicalIF":1.6,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of thyroid nodule to thyroid lobe volume ratio to measure fine needle aspiration cytologic malignancy risk of thyroid nodules in the pediatric population.","authors":"Frantzlee LaCrete, Blake Welker, Andrew Li, Alessandra Manoylova-Vedder, Naim Mitre, Meghan Tracy, David D Williams, Yoon Cho, John P Dahl","doi":"10.1016/j.ijporl.2026.113047","DOIUrl":"https://doi.org/10.1016/j.ijporl.2026.113047","url":null,"abstract":"<p><strong>Introduction: </strong>Pediatric thyroid cancer incidence is rising, but ultrasound (US) surveillance and biopsy thresholds remain highly debated due to multiple practice guidelines and limited supporting evidence.</p><p><strong>Objective: </strong>To evaluate thyroid nodule to lobe (NL) volume ratios across ultrasound-guided fine-needle aspiration (FNA) biopsy status, pathology, and TI-RADS recommendation criteria.</p><p><strong>Methods: </strong>After IRB approval, we retrospectively reviewed patients less than 21 years old who underwent thyroid US and FNA at a single institution (Figure 1). Nodule volume was divided by lobe volume to yield the volume ratio. Two-sample Wilcoxon rank-sum (Mann-Whitney) tests evaluated the ratio by biopsy status, Bethesda classification (BC), and TI-RADS criteria recommendation (Figure 2).</p><p><strong>Results: </strong>Among 122 patients, 92 (75.4%) were female and 30 (24.6%) were male; 379 nodules met the criteria for US review. The median NL ratio for the biopsy group was higher than the no biopsy group [0.14 (IQR: 0.04,0.38) vs 0.03 (IQR: 0.01,0.07); p < 0.0001]. When evaluating the BC to the NL ratio, there were 114 individuals with 323 eligible nodules. The median NL ratio was higher in the malignant group compared to the not malignant group [0.26 (IQR: 0.11,0.50) vs 0.12 (IQR: 0.04,0.34); p = 0.0032]. Additionally, the median NL ratio was greater for the TI-RADS biopsy recommended group compared to no TI-RADS biopsy recommended group [0.34 (IQR: 0.17,0.57) vs 0.05 (IQR: 0.03,0.12); p < 0.001].</p><p><strong>Conclusion: </strong>We found significantly greater NL ratios in pediatric patients with malignant thyroid FNAs. Higher NL ratios were found for individuals meeting criteria for biopsy based on TI-RADS. Further investigation is warranted to assess the NL ratio as an objective adjunct for determining pediatric thyroid nodule biopsy thresholds and optimizing US-based surveillance in the pediatric population.</p>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"211 ","pages":"113047"},"PeriodicalIF":1.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 2025 American society of pediatric otolaryngology workforce and compensation survey: Current state and future directions","authors":"Lyndy J. Wilcox,&nbsp;Cristina M. Baldassari,&nbsp;Amy C. Brenski,&nbsp;Emily Boss,&nbsp;John Carter,&nbsp;David H. Chi,&nbsp;William O. Collins,&nbsp;Charles A. Elmaraghy,&nbsp;Andrew J. Tompkins,&nbsp;Craig S. Derkay,&nbsp;the ASPO 2025 Workforce and Compensation Committee","doi":"10.1016/j.ijporl.2026.112970","DOIUrl":"10.1016/j.ijporl.2026.112970","url":null,"abstract":"<div><h3>Objective</h3><div>To provide an updated comprehensive assessment of the Pediatric Otolaryngology workforce in the United States inclusive of compensation, productivity, practice patterns, and on-call burden.</div></div><div><h3>Study design</h3><div>Cross-sectional electronic survey.</div></div><div><h3>Methods</h3><div>A structured electronic survey was developed by members of the American Society of Pediatric Otolaryngology (ASPO) Workforce and Compensation Committee. The survey evaluated six domains: demographics, compensation, workforce dynamics, productivity, on-call burden, and future priorities, and was distributed to all 480 presumedly actively-practicing, domestic ASPO members.</div></div><div><h3>Results</h3><div>The survey response rate was 68% (327/480). Ninety-one percent of respondents held an academic appointment with relatively equal percentages of each rank responding. The median clinical compensation was $525,000, which is a 17.4% increase from the 2019 ASPO survey median and 27.4% higher than the median reported by the AAO-HNS 2023 workforce survey. Median income varied by age, gender, and geographic region, but compensation per wRVU did not differ by gender. Over 80% of respondents noted increased wait times for completing patient appointments and elective surgeries. Ninety-four percent of practices employ advanced practice providers and anticipate additional hires. Difficulty filling open positions, anticipated workforce shortages, and concerns about provider retention were prevalent themes expressed by respondents.</div></div><div><h3>Conclusions</h3><div>Despite increasing compensation for pediatric otolaryngologists since 2019, workforce sustainability remains a pressing concern. These data provide a contemporary, specialty-specific analysis of the pediatric otolaryngology workforce that varies significantly from estimates published by large national organizations. Ongoing physician-led assessment can highlight the value of pediatric otolaryngologists and determine priorities for organizational advocacy.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"208 ","pages":"Article 112970"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants influencing variability in outcomes of prelingual cochlear implantation","authors":"Mona Elrabie Ahmed ,&nbsp;Esraa Aly ,&nbsp;Eman Mostafa","doi":"10.1016/j.ijporl.2026.112756","DOIUrl":"10.1016/j.ijporl.2026.112756","url":null,"abstract":"<div><h3>Objective</h3><div>To identify factors affecting cochlear implantation (CI) outcomes in pre-lingual deaf children, focusing on language development.</div></div><div><h3>Method</h3><div>A cross-sectional study of 106 pre-lingual deaf children who received unilateral CI was conducted to analyse factors influencing their language and speech outcomes.</div></div><div><h3>Results</h3><div>The average age of participating children was 83 ± 31.6 months; 53.8% were male, and 36.8% attended regular school programs. Most parents had higher education (64.2% of fathers, 55.7% of mothers), and 58.5% belonged to a low socioeconomic level. Hearing loss diagnosis was delayed: 37.7% were diagnosed at 6–12 months, 24.5% at 12–24 months, with an average auditory deprivation of 18.6 ± 13.3 months. Average CI age was 41.9 ± 14.2 months; 40.1% had consanguineous parents. Language outcomes were positively associated with speech after hearing aid use and negatively with longer auditory deprivation. Parent education, socioeconomic status, age of deafness, and family history were not significantly linked to language improvement. Children undergoing ≥3 years of post-implant rehabilitation showed greater language development than those with ≤3 years.</div></div><div><h3>Conclusion</h3><div>CI leads to a statistically significant improvement in language quotient over time, and key factors affecting outcomes include prior speech after hearing aid use, length of auditory deprivation, and ongoing CI usage. The study highlights the need for culturally adapted parental counselling protocols and increased awareness through comprehensive information.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"203 ","pages":"Article 112756"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146180096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the epidemiology and severity of intracranial complications of pediatric upper respiratory tract infections after the COVID-19 pandemic","authors":"Mohammad Sabobeh ,&nbsp;Mark Betonio ,&nbsp;Thomas Spentzas ,&nbsp;Sandra Arnold ,&nbsp;Stephen Pishko ,&nbsp;Saad Ghafoor ,&nbsp;Nicolas Chiriboga","doi":"10.1016/j.ijporl.2026.112754","DOIUrl":"10.1016/j.ijporl.2026.112754","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"203 ","pages":"Article 112754"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146147655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can we use peak expiratory flow rate monitoring in recurrent respiratory papillomatosis?","authors":"S. Maistry ,&nbsp;L.A. Sibiya ,&nbsp;S. Thula","doi":"10.1016/j.ijporl.2026.112750","DOIUrl":"10.1016/j.ijporl.2026.112750","url":null,"abstract":"<div><h3>Background</h3><div>Recurrent respiratory papillomatosis (RRP) is a chronic, HPV-induced disease characterized by the growth of benign, wart-like lesions within the upper aerodigestive tract, most commonly affecting the larynx. These lesions can lead to progressive voice changes and, in more severe cases, upper airway obstruction. Clinical evaluation, including flexible nasoendoscopic examination and symptom assessment, remains central to diagnosing and monitoring disease progression. However, due to the recurrent nature of RRP and the need for repeated surgical intervention, there is growing interest in identifying objective, non-invasive adjuncts to complement clinical evaluation and aid in disease monitoring.</div></div><div><h3>Aim</h3><div>To determine whether peak expiratory flow rate (PEFR) monitoring can serve as an effective adjunct for disease monitoring in RRP. To prove this, we aimed to demonstrate that post-operative PEFR values reflect expected clinical improvement when compared to pre-operative measurements, and that pre-operative PEFR correlates with disease severity when matched with intraoperative Derkay score.</div></div><div><h3>Methods</h3><div>38 patients were enrolled between July 2021 and September 2022. Each patient had PEFR readings recorded at each visit. Patients requiring surgical intervention, pre-operative and post-operative PEFR were recorded and Derkay scored intraoperatively (n = 30).</div></div><div><h3>Results</h3><div>Whilst the study size is small, the findings of this study do suggest that PEFR significantly improved post operatively, p value &lt; 0.001, 95% CI; and PEFR correlated with disease severity showing an inversely proportional relationship between pre operative PEFR and intraoperative Derkay score, a medium correlation was observed between PEFR and disease severity (<em>r</em> = −.0.309, P &gt; 0.05)</div></div><div><h3>Conclusion</h3><div>PEFR significantly improved in post-operative readings, indicating physiologic confirmation of the clinical observation that surgical debulking of respiratory papilloma causing upper airway obstruction results in functional improvements in airflow. PEFR correlates with disease severity, low PEFR correlated with higher Derkay scores.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"203 ","pages":"Article 112750"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146147654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial release from masking and localization among pediatric cochlear implant users","authors":"Puttaraju Sahana ,&nbsp;Puttabasappa Manjula","doi":"10.1016/j.ijporl.2026.112753","DOIUrl":"10.1016/j.ijporl.2026.112753","url":null,"abstract":"<div><h3>Aim &amp; objectives</h3><div>This study aimed to assess spatial hearing abilities in children using bimodal hearing devices. (1) comparing spatial release from masking (SRM) in monaural and bimodal conditions; (2) comparing horizontal localization error across conditions; and (3) examining the correlation between SRM and localization error.</div></div><div><h3>Method</h3><div>A cross-sectional, repeated-measures design was used with 43 Kannada-speaking children (aged 4–10 years) with bilateral severe-to-profound hearing loss, fitted with a cochlear implant (CI) in one ear and a hearing aid (HA) in the other. Spatial hearing was assessed using phonemically balanced word lists in noise (SRM task) and white noise bursts from eight loudspeakers (localization task). SRM was calculated as the difference in speech identification scores (SIS) between collocated and spatially separated speech-noise conditions. Localization was measured using root mean square (RMS) error.</div></div><div><h3>Results</h3><div>SRM was significantly higher in the bimodal condition (M = 3.09) than monaural (M = 1.23), <em>t</em> (42) = 3.15, <em>p</em> &lt; 0.001, <em>d</em> = 0.49. Localization accuracy also improved with bimodal hearing (M = 82.27° vs. 105.88°), <em>F</em> (1,42) = 100.79, <em>p</em> &lt; 0.001, η_p² = 0.706. A significant negative correlation (<em>r</em> = −0.518, <em>p</em> &lt; 0.001) was found between SRM and localization error.</div></div><div><h3>Conclusions</h3><div>Bimodal hearing significantly enhances spatial hearing in children, improving both speech-in-noise perception and localization. The correlation between SRM and localization suggests shared spatial processing mechanisms. These findings support the clinical importance of bimodal device use, especially in settings where bilateral implantation is not feasible, and highlight the need for individualized auditory management.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"203 ","pages":"Article 112753"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146179300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hematologic indices in pediatric sleep-disordered breathing: a retrospective case-control study","authors":"Rita Teixeira Carvalho ,&nbsp;Francisco Alves de Sousa ,&nbsp;João Carvalho Almeida ,&nbsp;Manuel Ferreira de Magalhães ,&nbsp;Marta Rios ,&nbsp;Miguel Bebiano Coutinho ,&nbsp;Mariline Santos","doi":"10.1016/j.ijporl.2026.112755","DOIUrl":"10.1016/j.ijporl.2026.112755","url":null,"abstract":"<div><h3>Introduction</h3><div>Pediatric obstructive sleep-disordered breathing (OSDB), commonly caused by adenotonsillar hypertrophy, ranges from primary snoring to obstructive sleep apnea syndrome (OSAS) and is a frequent reason for pediatric otolaryngology referral. OSDB leads to intermittent hypoxia, oxidative stress, systemic inflammation, and may activate the coagulation cascade, contributing to metabolic, cardiovascular, and neurocognitive complications. While these effects are more well-documented in adults, pediatric studies also report associations with obesity, insulin resistance, behavioral issues, and cognitive impairments. Diagnosis remains challenging due to the resource demands of polysomnography, prompting interest in alternative tools, including hematological biomarkers. In adults, markers like neutrophil-to-lymphocyte (N/L) and platelet-to-lymphocyte (P/L) ratios, as well as mean platelet volume (MPV), have shown promise; however, data in pediatric population are scarce.</div></div><div><h3>Objectives</h3><div>To compare hematological parameters in children with OSDB to those without OSDB.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed data from children who were indicated for primary otorhinolaryngology surgery between January and May 2024. Pre-operative hematological data from children with OSDB (cases) were compared to those without OSDB (controls).</div></div><div><h3>Results</h3><div>166 patients (75 females, 91 males; mean age 5.4 ± 2.4 years; mean weight 22.3 ± 10.2 kg) were included. 85 children (51.2%) had OSDB. No significant differences were found between groups regarding age, sex, or weight (p &gt; 0.05). Children with OSDB had significantly higher neutrophil-to-lymphocyte ratios (N/L ratio) (OSDB: 1.71 ± 1.02 vs. controls: 1.40 ± 0.67, p = 0.026) and platelet counts (OSDB: 328,152.94 ± 69,961.30 vs. controls: 302,876.54 ± 74,327.38, p = 0.025). No significant differences were encountered regarding neutrophil count (OSDB: 4260.59 ± 1755.87 vs controls: 3736.05 ± 1717.90, p = 0.054), total leukocyte count (OSDB: 8275.88 ± 1957.93, controls: 7624.57 ± 2351.98, p = 0.054) platelet-to-lymphocyte ratio (OSDB: 127.62 ± 49.50 vs controls: 114.17 ± 38.01, p = 0.052) and other hematological data, including coagulability state (p &gt; 0.05 for prothrombin time, INR and APTT).</div></div><div><h3>Conclusions</h3><div>OSDB in children is associated with significantly increased N/L ratio and platelet count, suggesting a potential systemic inflammatory response. Further research is needed to determine the clinical significance of these findings.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"203 ","pages":"Article 112755"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146192516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}