International journal of pediatric otorhinolaryngology最新文献

{"title":"Otolaryngological manifestations of cystic fibrosis in children: A systematic review","authors":"Alberto Saibene ,&nbsp;Anastasia Urbanelli ,&nbsp;Chimene Coudré ,&nbsp;Letizia Nitro ,&nbsp;Anneclaire Vroegop ,&nbsp;Barbara Lejeune ,&nbsp;Nicolien van der Poel","doi":"10.1016/j.ijporl.2025.112238","DOIUrl":"10.1016/j.ijporl.2025.112238","url":null,"abstract":"<div><h3>Purpose</h3><div>Cystic fibrosis (CF) is the most common autosomal recessive disorder in the Caucasian population. Otolaryngological manifestations pose a significant impact on the quality of life of children with CF. The primary aim of this review is to provide a state of the art update of current literature on the otolaryngological manifestations of CF in children.</div></div><div><h3>Methods</h3><div>We systematically reviewed the PubMed, Cochrane Library, Embase and Web of Science databases, for prospective studies including pediatric patients with cystic fibrosis, reporting on otolaryngological manifestations. After assessment of the risk of bias and quality of the included studies, data were extracted.</div></div><div><h3>Results</h3><div>The search retrieved 6745 unique items after duplicate removal. After three selection rounds and quality assessment, 38 articles were ultimately retained for data extraction. The total number of participants in the studies was 1981. Most studies were prospective cohort studies (n = 28). The articles were divided into six groups (ear/speech disorders - aminoglycoside ototoxicity (n = 10); otolaryngology-related quality of life (n = 5); nasal and paranasal sinuses (n = 11); sleep disorders (n = 3); paranasal sinuses imaging (n = 5); other (n = 4)).</div></div><div><h3>Conclusion</h3><div>The most common otolaryngological manifestation of children with CF is chronic rhinosinusitis, but CF can have other otolaryngological-related pathologies such as hearing loss, middle ear problems, sleep apnea syndrome, and decreased smell and/or taste functions. We found a considerable gap in the literature if we would draw evidence-based conclusions on diagnosis and management of otolaryngological manifestations in children with CF.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112238"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensory processing in Autism Spectrum Disorder: Insights into misophonia, and hyperacusis in a pediatric population","authors":"Manasi Sadanand Katikar ,&nbsp;Anuprarthana Devi ,&nbsp;Prashanth Prabhu","doi":"10.1016/j.ijporl.2025.112241","DOIUrl":"10.1016/j.ijporl.2025.112241","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to investigate the prevalence of misophonia and hyperacusis in children with Autism Spectrum Disorder (ASD), focusing on gender differences and sensory processing challenges. The research further explores how these sensory sensitivities impact daily functioning and how they may differ across genders in a pediatric population.</div></div><div><h3>Methods</h3><div>A total of 60 children aged 2–12 years, diagnosed with ASD, intellectual disability, borderline intellectual functioning, or co-occurring ADHD, participated in the study. Parental consent was obtained, and parents completed the Misophonia Impact and Hyperacusis Impact Questionnaires, which assess the presence and severity of sound sensitivities. Data analysis included frequency distributions and Spearman's rank correlation to examine potential associations between age and the severity of sensory symptoms.</div></div><div><h3>Results</h3><div>The study found that 45 % of participants exhibited misophonia, and 38 % showed signs of hyperacusis. A slightly higher prevalence of misophonia and hyperacusis was observed in female participants (50 % and 43 %, respectively) compared to males (43 % and 37 %, respectively). No significant correlation was found between the age of participants and the severity of misophonia (r = 0.22, p &gt; 0.05) or hyperacusis (r = 0.19, p &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>Misophonia and hyperacusis are prevalent sensory challenges among children with ASD, with a slightly higher occurrence in females. These findings suggest that sensory sensitivities persist across developmental stages and may be more pronounced in females. Early identification and gender-sensitive, sensory-focused interventions are critical for improving the quality of life and daily functioning of children with ASD. Future research should explore the underlying mechanisms of these sensory sensitivities to enhance intervention strategies across diverse populations.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112241"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consanguinity and hearing loss prevalence among Saudi Arabia population","authors":"Shawq Fayez Aljabri ,&nbsp;Shawg Saleh Alrumaih ,&nbsp;Yousef M Al Mashhrawi ,&nbsp;Muhannad Sulaiman Alhusayni ,&nbsp;Rawan Abdulrahman Bayamin ,&nbsp;Reem Mansour Kublan Alkublan ,&nbsp;Amal Binhazzaa","doi":"10.1016/j.ijporl.2024.112209","DOIUrl":"10.1016/j.ijporl.2024.112209","url":null,"abstract":"<div><h3>Background</h3><div>Childhood hearing loss (CHL) is a condition that can have a variety of causes, including genetic and environmental and its prevalence is thought to be high in Saudi Arabian population mainly due to consanguineous unions. This systematic literature review aims to conclude the prevalence of hereditary hearing loss and its risk factors among the Saudi population.</div></div><div><h3>Methods</h3><div>In September 2023, a thorough search was performed on the PubMed, CENTRAL, MEDLINE, and EMBASE databases. Two reviewers independently reviewed the literature and gathered data. The search criteria encompassed ethics and dissemination. The systematic review and meta-analysis utilized information sourced from openly accessible research articles, thereby avoiding the involvement of any individuals or animals in the study.</div></div><div><h3>Results</h3><div>The search identified nine relevant studies. Consanguinity prevalence ranged from 21.1 % to 80.8 %, with first cousin marriages being common. The prevalence of CHL among offspring from consanguineous marriages was consistently higher than non-consanguineous unions. A meta-analysis was not feasible due to heterogeneity in study designs and outcomes. The risk of CHL in offspring from consanguineous marriages was significantly elevated, as evidenced by Almazroua's study (2020) reporting a 3.5 times higher risk. Genetic factors and hereditary influences were underscored by the studies, with variations in prevalence and risk factors.</div></div><div><h3>Conclusion</h3><div>This systematic review reveals a substantial association between consanguinity and an increased risk of congenital sensorineural hearing loss in the Saudi Arabian population. The prevalence of consanguinity, coupled with the consistently higher prevalence of CHL among offspring from such unions, emphasizes the need for targeted public health interventions. Educational programs, genetic counseling, and expanded premarital screening programs are warranted to address the impact of consanguinity on hearing health in Saudi Arabia.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112209"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143295233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genotypes and clinical phenotypes of pediatric patients with NOG variants: Middle ear surgical outcomes from a Tertiary Center in South Korea","authors":"Sang-Yoon Han ,&nbsp;Sung Ho Cho ,&nbsp;Sung Ho Jung ,&nbsp;Myeongsin Kang ,&nbsp;Myung-Whan Suh ,&nbsp;Moo Kyun Park ,&nbsp;Jun Ho Lee ,&nbsp;Sang-Yeon Lee","doi":"10.1016/j.ijporl.2025.112230","DOIUrl":"10.1016/j.ijporl.2025.112230","url":null,"abstract":"<div><h3>Objective</h3><div>Although <em>NOG</em> variants are linked to congenital stapes fixation and conductive hearing loss (CHL), little is known about middle ear surgery outcomes and the characteristics of accompanying inner ear anomalies. We explored auditory phenotypes in patients with <em>NOG</em> variants, with a focus on the outcomes of middle ear surgery.</div></div><div><h3>Methods</h3><div>This study included 11 patients from five unrelated Korean families harboring <em>NOG</em> variants. Genomic investigations were conducted using whole-exome sequencing and whole-genome sequencing. The clinical phenotypes, including pre- and postoperative audiological profiles, radiological abnormalities, and other comorbidities, were analyzed.</div></div><div><h3>Results</h3><div>The average age at genetic testing was 8.2 years (range, 0–13 years). Two previously reported <em>NOG</em> variants (c.509C &gt; T:p.Pro170Leu and c.252dup:p.Glu85ArgfsTer97) and three novel <em>NOG</em> variants, including the c.187G &gt; T: p.Glu63Ter and two cryptic large deletion within the 17q22.2 region, were identified. All patients exhibited non-progressive CHL. Inner ear anomalies were documented in two patients, with variations such as cochlea and vestibular dysplasia. In this study, seven ears of four patients underwent stapedotomy, resulting in a significantly reduced air-bone gap of 10.18 ± 1.48 dB (<em>P</em> = 0.016), with sustained improvement. Conversely, patients carrying p.Pro170Leu variant, which is associated with poor outcomes for middle ear surgery, were excluded from surgical consideration.</div></div><div><h3>Conclusion</h3><div>We expanded the spectrum of genotypes and auditory phenotypes associated with <em>NOG</em> variants. Surgical intervention for CHL underlying <em>NOG</em> variants elicits favorable outcomes. However, clinicians should consider the potential for poor prognosis in certain <em>NOG</em> variants. Collectively, identifying <em>NOG</em> variants could guide the treatment strategies to improve CHL.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112230"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aspirated foreign bodies in children: 10-Years experience in a single tertiary centre in New Zealand","authors":"Jae Hyun Jeong ,&nbsp;Jeyasakthy Saniasiaya ,&nbsp;Craig McCaffer","doi":"10.1016/j.ijporl.2025.112234","DOIUrl":"10.1016/j.ijporl.2025.112234","url":null,"abstract":"<div><h3>Objective</h3><div>Aspirated foreign bodies (FB) are potentially life-threatening conditions which can be challenging to diagnose in children. The previous similar study from our hospital, published in 2014, created a guideline suggesting when to proceed to laryngobronchoscopy (LB) in suspected FB aspiration with over 99 % sensitivity. The grading system included the presence or absence of acute history, positive examination, and/or radiological findings, including witnessed choking, dysphonia, stridor, wheezing, or reduced air entry on examination or abnormal radiological findings. The current study reviewed a further 10 years and 5 months of data to re-evaluate the ongoing diagnostic usefulness of the three positive findings in children with suspicion of aspirated FB.</div></div><div><h3>Methods</h3><div>We undertook a retrospective review of all LB performed at our institution for suspected acute FB aspiration from August 2013 to January 2023. We analysed patient characteristics, clinical examination, radiological findings, and outcomes.</div></div><div><h3>Results</h3><div>We found a total of 100 children under the age of 16 years who underwent LB for suspected FB aspiration. The mean age of our study population was 2.6 years. The population demographics were similar to the results from the previous study from our institution, with Māori and Pasifika children having the highest probability of finding a FB on LB. Male children presenting for suspected FB aspiration are 1.39 times more likely than female children to have a foreign body at LB (p = 0.04). Overall, having two or more positive findings had a sensitivity of 100 %. History or examination alone are more sensitive (both 95.6 %) but less specific (12.5 % and 31.3 %, respectively). Abnormal radiology alone was more specific (75.0) but less sensitive (77.9 %). The most common site of FB was the right bronchial tree (45.6 %), followed by the left (39.7 %). 95 % of FB were organic, and 54 % were nuts. The negative bronchoscopy rate was 32 %.</div></div><div><h3>Conclusion</h3><div>Two or more positive indicators in history, examination and radiological findings continue to be highly sensitive predictors for the presence of an aspirated foreign body in our paediatric population. We recommend a future large-scale multicentre study to confirm how applicable these findings would be to a broader cohort of patients.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112234"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the therapeutic effect of EarWell ear orthotics on elderly children with congenital ear deformities within 98 days","authors":"Jie OuYang,&nbsp;Xiaoqin Wang","doi":"10.1016/j.ijporl.2025.112236","DOIUrl":"10.1016/j.ijporl.2025.112236","url":null,"abstract":"<div><h3>Objective</h3><div>To observe the efficacy of EarWell ear orthotics in treating congenital ear deformities in older children (≥7 weeks) within 98 days.</div></div><div><h3>Method</h3><div>A retrospective study was conducted on 58 infants (69 ears) aged 7–14 weeks after birth. Divided into three groups: A (7–9 weeks old, 26 ears), B (10–12 weeks old, 23 ears), and C (13–14 weeks old, 20 ears). Analyze the differences in treatment time, effective rate, six-month recurrence rate, and incidence of complications among three age groups.</div></div><div><h3>Result</h3><div>Age group A had the shortest treatment time (25.13 ± 3.28d) and the highest effective rate (84.61 %), while age group C had the longest treatment time (48.35 ± 7.64d) and the lowest effective rate (60.00 %), with statistically significant differences (p &lt; 0.05); The six-month recurrence rate and incidence of complications in the A age group were lower than the other two groups, and the difference was statistically significant (p &lt; 0.05); The recurrence cases in the three age groups are mainly concentrated in the cup ear and the prominent ear.</div></div><div><h3>Conclusion</h3><div>EarWell ear orthotics can still be chosen for morphological correction of congenital ear deformities in children aged 7–14 weeks. However, the effectiveness of treatment may be affected by the age of treatment and the type of malformation. The older the age of treatment, the lower the effectiveness of orthosis treatment, the longer the treatment time, and the higher the probability of complications. Cup ears and prominent ear over 7 weeks old have a higher recurrence rate after treatment, and it is recommended to correct them as soon as possible.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112236"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of small-incision and traditional techniques in costal cartilage harvesting: Outcomes on thoracic deformities and scar appearance","authors":"Jiajun Zhi ,&nbsp;Yicheng Liu ,&nbsp;Xiaochen Sun,&nbsp;Jingwei Feng,&nbsp;Guanwen Ding,&nbsp;Bo Pan,&nbsp;Chuan Li","doi":"10.1016/j.ijporl.2025.112235","DOIUrl":"10.1016/j.ijporl.2025.112235","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to compare the postoperative thoracic deformity and scar aesthetic outcomes of auricular reconstruction between the conventional large-incision technique and small-incision technique with perichondrium preservation for costal cartilage harvesting.</div></div><div><h3>Methods</h3><div>A retrospective analysis was performed on 134 patients who underwent auricular reconstruction using tissue expanders and autologous costal cartilage harvested from the right chest wall between January 2021 and September 2023. Patients were divided into two groups according to the harvesting technique: the traditional large-incision group (n = 64) and the small-incision group with perichondrium preservation (n = 70). Preoperative and postoperative chest CT scans were reviewed for thoracic deformities by measurements of the modified Haller Index (mHI) and modified correction index (mCI). Thoracic scar dimensions were measured in postoperative follow-up.</div></div><div><h3>Results</h3><div>In the conventional group, significant difference were observed between the left and right hemithorax in anterior-posterior diameter, maximum transverse diameter, cross-sectional area, and mHI values (p &lt; 0.05), showing thoracic deformities. In contrast, within the small-incision group, there were no significant differences between hemithoraces. Additionally, postoperative thoracic scars were significantly smaller in the small-incision group, with shorter scar length (5.63 ± 1.33 cm vs. 11.44 ± 1.31 cm) and width (1.41 ± 0.55 cm vs. 3.75 ± 1.54 cm; p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The small-incision technique with perichondrium preservation significantly reduces postoperative thoracic deformities and results in smaller, less conspicuous scars compared to the traditional large-incision method. This approach minimizes disruption to the chest wall structure and reduces donor-site morbidity, offering improved patient outcomes.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112235"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indications for tracheostomy placement in pediatric patients with cerebral palsy","authors":"Elizabeth Fisher ,&nbsp;Taher Valika","doi":"10.1016/j.ijporl.2025.112226","DOIUrl":"10.1016/j.ijporl.2025.112226","url":null,"abstract":"<div><h3>Background</h3><div>Cerebral palsy (CP) is the most common neuromuscular disorder in children, and children with CP are at increased risk of respiratory distress potentially requiring tracheostomy placement. Previous studies have characterized indications for tracheostomy in neurologically compromised children, however no studies focus specifically on children with CP. The purpose of this study was to identify the indications for tracheostomy placement, sites of airway obstruction, and rate of decannulation in children with CP.</div></div><div><h3>Methods</h3><div>We conducted a single-center retrospective chart review of all patients who presented with cerebral palsy and required tracheostomy at our center between 2005 and 2023. Patients were categorized according to primary indication for tracheostomy placement. The most common sites of airway obstruction in the cohort were recorded. The date of decannulation was recorded for those patients who had undergone decannulation.</div></div><div><h3>Results</h3><div>933 patients with tracheostomies were identified, of whom 169 (18 %) had CP and 122 met inclusion criteria. The median age at tracheostomy placement was 1.69 (IQR 0.539–6.609) years. The most common indications for tracheostomy placement were: prolonged intubation or BiPAP dependence (81 %), airway obstruction/hypotonia (13 %), and aspiration/recurrent respiratory infection (6 %). At the time of tracheostomy placement: 38 % of patients had a single site of upper airway obstruction, while 27 % had multi-level obstruction. The most common sites of upper airway obstruction were the supraglottis (23.0 %), tongue base (12 %), and the tonsils/pharyngeal wall (8 %). 24 % of patients had tracheobronchomalacia, and 16 % had subglottic stenosis. Among all patients, 4 of 122 (3 %) were ultimately decannulated.</div></div><div><h3>Conclusions</h3><div>Patients in our cohort most often received tracheostomy after failure of less invasive ventilation therapies. Tracheostomy placement occurred at a young age. Patients presented with a variety of sites of airway obstruction. Decannulation rate in this cohort was low. Further work is needed to confirm indications for tracheostomy placement and decannulation rate in this population.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112226"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental anxiety and catastrophizing in pediatric tonsillectomy pain control: A multivariate analysis","authors":"Ben B. Levy ,&nbsp;Jennifer M. Siu ,&nbsp;Brittany N. Rosenbloom ,&nbsp;Melanie Noel ,&nbsp;Tanya Chen ,&nbsp;Nikolaus E. Wolter","doi":"10.1016/j.ijporl.2025.112244","DOIUrl":"10.1016/j.ijporl.2025.112244","url":null,"abstract":"<div><h3>Objective</h3><div>Parental anxiety and/or catastrophizing may bias the interpretation of children's pain and administration of analgesia post-tonsillectomy. We aimed to determine whether high levels of parental anxiety and/or catastrophizing impact child pain intensity interpretation and administration of analgesia.</div></div><div><h3>Methods</h3><div>Child-parent dyads were recruited from a tertiary care institution between July 2017–December 2019. Preoperative parental anxiety and catastrophizing were assessed using self-report measures. Postoperative data on child and parent pain intensity, as well as analgesia use, were collected up to 2 weeks post-surgery. Multivariable logistic regression models were created to assess predictors of postoperative child pain intensity and analgesia use.</div></div><div><h3>Results</h3><div>Our cohort included 234 child-parent dyads. Median child age was 5 years (IQR, 4–6), and 9.0 % of children (n = 21) had a medical comorbidity. Both child- and parent-reported pain intensity were highest on postoperative day 2 (3.65 [SD = 3.08] and 3.67 [SD = 2.51], respectively). Parental catastrophizing did not predict analgesia use at home, although a minimal significant decrease in the odds of analgesia administration was observed on postoperative day 7 (OR 0.932, <em>p</em> = 0.017). Maximal parental anxiety did not predict higher odds of increased child postoperative pain intensity on any postoperative day.</div></div><div><h3>Conclusion</h3><div>Parental catastrophizing prior to tonsillectomy has minimal predictive value for analgesia use postoperatively. Children may be successfully advocating for their own pain control as parental anxiety and catastrophizing do not appear to be unduly influencing analgesia administration. Future studies should explore the impact of parental anxiety on vulnerable pediatric populations who may be unable to self-advocate for pain management.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"190 ","pages":"Article 112244"},"PeriodicalIF":1.2,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumococcal revaccination in pediatric patients with sinusitis","authors":"William G. Cohen ,&nbsp;Chau Phung ,&nbsp;Dominick Rich ,&nbsp;Fengling Hu ,&nbsp;Jana Bradley ,&nbsp;Mark D. Rizzi ,&nbsp;Adva Buzi","doi":"10.1016/j.ijporl.2025.112242","DOIUrl":"10.1016/j.ijporl.2025.112242","url":null,"abstract":"<div><h3>Objectives</h3><div>In pediatric patients with sinusitis and suspected low pneumococcal antibody titers, we aimed to determine the association between a pneumococcal polysaccharide vaccine booster dose (PPSV23) and healthcare utilization.</div></div><div><h3>Methods</h3><div>Pediatric patients with a diagnosis of sinusitis, a PPSV23 booster dose, and pre-vaccine anti-pneumococcal antibody titers (age 2–16) were abstracted from the medical records system. Sinusitis-related healthcare encounters and antibiotic prescriptions were measured for 2 years before and after PPSV23 vaccination. A mixed effects negative binomial regression was utilized to compare pre and post-vaccine healthcare utilization while accounting for age and sex.</div></div><div><h3>Results</h3><div>A total of 233 patients were included in the study analysis. Mean age at pre-vaccination titer was 7.99 years (±3.83), 47 (20.2 %) were immunocompromised, and nearly all patients received the complete childhood pneumococcal vaccine series. When comparing pre and post-vaccination periods, encounters decreased from an average of 2.70 (95 % CI: [2.29, 3.10]) to 1.23 (95 % CI: [1.00, 1.46]). Antibiotic prescriptions decreased from 2.58 (95 % CI: [2.17, 2.98]) to 1.18 (95 % CI: [0.93, 1.42]). Mixed effects modeling demonstrated the number of encounters after vaccination decreased 51.1 % as compared to before vaccination (95 % CI: [42.9, 58.2], p &lt; 0.001) and the number of antibiotic prescriptions decreased 51.3 % (95 % CI: [42.9 %, 58.6 %], p &lt; 0.001). Among immunocompromised patients, encounters were decreased by 46.9 % (95 % CI: [26.2 %, 62.1 %], p &lt; 0.001) and antibiotic prescriptions by 49.2 % (95 % CI: [28.5 %, 64.2 %], p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>PPSV23 booster vaccination was associated with a significant decrease in sinusitis-related healthcare encounters and antibiotic use among pediatric patients, including those who are immunocompromised.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"190 ","pages":"Article 112242"},"PeriodicalIF":1.2,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}