International journal of pediatric otorhinolaryngology最新文献

{"title":"Musical pitch and timbre perception in stuttering children","authors":"Emel Arslan-Sarımehmetoğlu ,&nbsp;Mustafa Yüksel","doi":"10.1016/j.ijporl.2025.112214","DOIUrl":"10.1016/j.ijporl.2025.112214","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aims to evaluate musical pitch and timbre perception in children who stutter and compare the results with typically developing children.</div></div><div><h3>Methods</h3><div>A total of 50 participants were included in the study, consisting of 25 children with stuttering (mean age = 10.06 years; range 6–17 years) and 25 typically developing children (mean age = 10.38 years; range 7–16 years). Participants were administered Pitch Direction Discrimination (PDD) and Timbre Recognition (TR) tests in the original form of The Clinical Assessment of Music Perception. Both subtests were administered in a quiet room, and the children used headphones to receive auditory stimuli.</div></div><div><h3>Results</h3><div>The mean PDD score of the stuttering group was 3.60 semitones (SD = 2.71), while the mean score of the typically developing children was 2.26 semitones (SD = 1.43). In the TR test, the mean accuracy of the stuttering group was 53.17 % (SD = 21.69), while the mean accuracy of the typically developing children were 65.33 % (SD = 19.64). The difference between the two groups was statistically significant in the PDD (t(48) = 2.17, p = 0.03) and TR (t(48) = −2.08, p = 0.04) tests.</div></div><div><h3>Conclusions</h3><div>The study found that children who stuttered had poorer pitch and timbre musical perception skills than age-matched peers who were typically developing children. The lower success rates of the stuttering group on both tests may indicate general deficits in auditory processing, which could be related to attention and short-term memory processing.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112214"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143352952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of relationship between the language development and parental attitudes in children with cochlear implant","authors":"Oznur Cavus Kocagul ,&nbsp;Merve Meral Cetinkaya","doi":"10.1016/j.ijporl.2025.112228","DOIUrl":"10.1016/j.ijporl.2025.112228","url":null,"abstract":"<div><h3>Objective</h3><div>The primary aim of this study was to examine the relationship between parental attitudes and language development in preschool children with cochlear implants. In addition, the study aimed to examine parental attitudes in relation to socio-demographic and cochlear implant related variables.</div></div><div><h3>Methods</h3><div>This study is based on the relational survey model. A total of 47 children aged 2–5 years, 23 girls and 24 boys, and one of their parents were included in the study. Test of Early Language Development Test-3-Turkish Adaptation was applied to measure the language development levels of the children. In order to determine parental attitudes, 5-point Likert-type Parental Attitude Scale consisting of 46 items was completed by the parents.</div></div><div><h3>Results</h3><div>Democratic attitudes were found to be the most common type of parental attitude (4.33 ± 0.45). Significance was found for overprotective parental attitudes according to cochlear implant age and economic income level. Statistically significant, moderate negative correlation was found between overprotective parental attitude scores and receptive language, expressive language, and composite verbal language scores (r: 0.401; r: 0.337; r: 0.390; p &lt; 0.05, respectively).</div></div><div><h3>Conclusion</h3><div>It was concluded that there was a relationship between overprotective parental attitude and language skills of preschool children with cochlear implants. Overprotective parental attitudes were significantly associated with cochlear implant age and economic income level, with earlier cochlear implant age and higher income correlating with less overprotection.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112228"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Children with a tracheostomy: Global speech-language therapists' practice","authors":"Anna Miles ,&nbsp;Sarah Wallace ,&nbsp;Louise Bax ,&nbsp;Melissa Keesing ,&nbsp;Louise Edwards ,&nbsp;Vicky Thorpe","doi":"10.1016/j.ijporl.2025.112237","DOIUrl":"10.1016/j.ijporl.2025.112237","url":null,"abstract":"<div><h3>Purpose</h3><div>Speech-language Therapists (SLTs) are specialists in communication, feeding and swallowing as core members of the paediatric tracheostomy multidisciplinary team (MDT). Inconsistent tracheostomy care leads to staff and family frustration and delayed intervention. Little is known about international SLT tracheostomy practices.</div></div><div><h3>Methods</h3><div>This global survey explored training, clinical practices, perceived knowledge, skills and roles, and barriers for SLTs working with paediatric tracheostomy. Survey questions consisted of Likert scale and open-ended questions. 92 SLTs completed the survey representing 6 continents and 19 countries.</div></div><div><h3>Results</h3><div>Overall SLTs were confident in their knowledge of communication, and feeding but less confident in weaning, tracheostomy care skills (such as suctioning and cuff deflation) and specialist tracheostomy tube use (such as tracheostomy tubes with a subglottic suction port). Formal competency training was infrequent but most had access to supervision. Understanding of the SLT role by the MDT was perceived as good. Many felt managing one-way speaking valves was part of their role. The majority reported staffing, lack of guidelines and access to resources (one-way speaking valves and flexible endoscopic evaluation of swallowing) as barriers.</div></div><div><h3>Conclusions</h3><div>This expert opinion paper summarises the current evidence-base and international paediatric tracheostomy practice. SLTs were experienced and confident in tracheostomy. The SLT role varies internationally with a lack of formal written policy to guide practice and a variability in access to education.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112237"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative respiratory complications in intracapsular tonsillectomy and total tonsillectomy: Is there a difference?","authors":"Shraddha Mukerji ,&nbsp;Joshua Bedwell ,&nbsp;Ava Berrier ,&nbsp;Carolyn Chen ,&nbsp;Kathleen Hosek ,&nbsp;Rahul G. Baijal","doi":"10.1016/j.ijporl.2025.112216","DOIUrl":"10.1016/j.ijporl.2025.112216","url":null,"abstract":"<div><h3>Purpose</h3><div>The primary objective was to determine any difference in perioperative respiratory complications in children undergoing intracapsular tonsillectomy versus those undergoing total tonsillectomy for sleep-disordered breathing or obstructive sleep apnea.</div></div><div><h3>Methods</h3><div>All children undergoing total tonsillectomy from November 2015 to December 2017 and intracapsular tonsillectomy from May 2016 to July 2020 for sleep-disordered breathing or obstructive sleep apnea were included in the study.</div></div><div><h3>Results</h3><div>2408 patients underwent total tonsillectomy whereas 410 patients underwent intracapsular tonsillectomy. The incidence of major respiratory complications was 13.9 % for intracapsular tonsillectomy and 8.9 % for total tonsillectomy in an unmatched cohort and 13.8 % for intracapsular tonsillectomy and 10.5 % for total tonsillectomy in a matched cohort. Surgical technique was not significant for both major (OR:0.969, 95 % CI:0.596–1.573, p = 0.8979) and minor (OR 0.9, 95 % CI:0.431–1.878, p = 0.7785) respiratory complications in the unmatched cohort and also not significant for major (OR:0.996, 95 % CI:0.353 2.809, p = 0.9944) and minor (OR:1.5, 95 % CI:0.66–3.612, p = 0.31) respiratory complications in the matched cohort. Factors associated with an increased incidence of major perioperative respiratory complications in the unmatched cohort included race (Black or African American) (OR:1.768, 95 % CI:1.298–2.409, p = 0.0038), reactive airway disease (OR:1.814, 95 % CI:1.39–2.367, p=&lt;0.0001), and an upper respiratory infection (OR:1.631, 95 % CI:1.095–2.431, p = 0.0161) whereas reactive airway disease (OR:3.596,95 % CI:1.217–10.621, p=&lt;0.0206), an upper respiratory infection (OR:5.779, 95 % CI:1.392–23.99, p = 0.0157), and the presence of obstructive sleep apnea (OR:4.174, 95 % CI:1.242–14.025, p = 0.0208) were significant in the matched cohort.</div></div><div><h3>Conclusion</h3><div>There was no difference in perioperative respiratory complications in children undergoing intracapsular tonsillectomy versus total tonsillectomy.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112216"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review and meta-analysis of pathogenic GJB2 variants in the Asian population","authors":"Zeynep Ozgur ,&nbsp;Dillon Strepay ,&nbsp;Mustafa Husein ,&nbsp;Shaarav Ghose ,&nbsp;Maximilian Dawson ,&nbsp;Anita Jeyakumar","doi":"10.1016/j.ijporl.2025.112233","DOIUrl":"10.1016/j.ijporl.2025.112233","url":null,"abstract":"<div><h3>Objectives</h3><div>Define the extent to which pathogenic <em>GJB2</em> (gap junction beta-2) variants are responsible for non-syndromic hearing loss (NSHL) in the Asian population.</div></div><div><h3>Methods</h3><div>Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were followed. CINAHL, Embase, and PubMed's MEDLINE were accessed from 1997 to 2023 using permutations of the MeSH terms: “Asian,” ‘‘Southeast Asian,’’ “South Asian,” “East Asian,” “Southeastern Asian,” and “GJB2.” Additionally, all countries within the Indian subcontinent, Far East, and Southeast Asia, were included as key terms. Exclusion criteria included non-English publications, a non-Asian study population (per US Office of Management and Budget), and literature not investigating <em>GJB2</em>. An allele frequency analysis of pathogenic <em>GJB2</em> variants in the Asian population was performed and stratified by country of origin.</div></div><div><h3>Results</h3><div>One thousand one hundred and forty-one unique studies were identified, of which 420 met our inclusion criteria during the abstract screen. One hundred and ninety-five studies were included in the systematic review after full-text screen. Over 45 pathogenic variants were identified across 11 countries within the Indian subcontinent, Far East, and Southeast Asia. A total of 4,220,591 people from over 30 ethnic groups were included with ages ranging from 0 to 97 years. Of those with reported demographic information, 50 % (221,336/445,813) were female and 50 % (224,477/445,813) were male. The prevalence of pathogenic <em>GJB2</em> variants varied by country, with common variants including c.235del; p.Leu79Cysfs∗3, c.109G &gt; A; p.Val37Ile, and c.299_300del; p.His100Argfs∗14.</div></div><div><h3>Conclusion</h3><div>Variation in the prevalence of pathogenic <em>GJB2</em> variants is likely due to the wide diversity of ancestral contributions in the Asian population. There are limited studies on the prevalence of <em>GJB2</em> variants particularly for countries within the Indian subcontinent and Southeast Asia. Additional studies on the prevalence of <em>GJB2</em> variants in these countries as well as ethnic sub-groups may be helpful in the development of assays for high throughput diagnosis for patients with hereditary hearing loss.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112233"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Click Ordering Lateralization Test: Applicability and feasibility of a new paradigm for assessing sound lateralization behavior","authors":"Elizabeth Della Colette ,&nbsp;Carlos Alberto Leite Filho ,&nbsp;Camila Maia Rabelo ,&nbsp;Frank Musiek ,&nbsp;Eliane Schochat","doi":"10.1016/j.ijporl.2025.112215","DOIUrl":"10.1016/j.ijporl.2025.112215","url":null,"abstract":"<div><h3>Objective</h3><div>the present study aimed to investigate the applicability and feasibility of a new paradigm for assessing sound lateralization behavior.</div></div><div><h3>Design</h3><div>The Click Ordering Lateralization Test comprises two tracks (tracks 1 and 2), with 54 trials each. Each trial consists of one of nine intervals ranging from 0 to 230 ms between two noise bursts, whereby subjects must indicate on which side they first heard the noise. The COLT procedure was applied to 30 normal-hearing children (between 8 and 14 years old).</div></div><div><h3>Results</h3><div>the results indicated that an interaural time difference (ITD) of 0 ms functions as a control item, and after an ITD of 170 ms, the lateralization threshold reaches a ceiling effect. Different analysis methods were investigated in this study, with the total percentage score and a lateralization threshold of 5 hits deemed the most reliable methods. No differences were observed between test tracks and performance across the tracks was shown to be reliable and equivalent.</div></div><div><h3>Conclusions</h3><div>there are few procedures available to assess sound laterization in a clinical setting. This study presents the COLT as an easy-to-apply, reliable test for use in children aged between 8 and 14 years old.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112215"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143352953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Pediatric Mastoiditis Numbers and Related Complications Before During and After the COVID-19 Pandemic","authors":"Elie Khalifee ,&nbsp;Macaulay Ojeaga ,&nbsp;Kyle Singerman ,&nbsp;Meghan Tracy ,&nbsp;Emily Cramer","doi":"10.1016/j.ijporl.2025.112240","DOIUrl":"10.1016/j.ijporl.2025.112240","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate acute pediatric mastoiditis numbers and associated complications before, during, and after the COVID-19 pandemic.</div></div><div><h3>Methods</h3><div>A retrospective chart review of all children less than 18 years of age presenting to a pediatric tertiary medical center with acute mastoiditis from January 1, 2017 to October 30, 2023 was completed. Exclusion criteria included history of chronic mastoiditis, cholesteatoma and mastoidectomy. Demographic and clinical data were collected and included age, sex, race, ethnicity, duration between onset of symptoms and presentation, white blood cell count and C-reactive protein level, affected ear, intracranial and extracranial complications, procedures, readmission and reoperation, length of hospital stay, and culture results. Patients were classified in relation to the COVID pandemic into three groups: pre-COVID included patients presenting from January 1, 2017, until December 31, 2019, COVID from January 1, 2020, until December 31, 2021, and post-COVID from January 1, 2022, until October 30, 2023.</div></div><div><h3>Results</h3><div>A total of 89 patients, 49 males and 40 females, with a mean age of 53.8 ± 40.7 months were included. Twenty-four (27.0 %) patients presented in the pre-COVID, 14 (15.7 %) in the COVID, and 51 (57.3 %) in the post-COVID period. There was no difference in the mean duration between onset of symptoms and presentation across the groups (5.4 ± 4.4 days pre-COVID, 5.8 ± 6.8 days during COVID, and 8.5 ± 8.1 post-COVID, P = 0.16). The post-COVID mean annual number of mastoiditis cases (27.8 cases/year) was higher compared to pre-COVID (8 cases/year) and COVID (7 cases/year). Similarly, the post-COVID mean annual number of cases with complications (24 cases/year) was higher compared to pre-COVID (5 cases/year) and COVID (5.5 cases/year). Of note, the post-COVID mean annual number of cases with intracranial complications (12cases/year) was also higher compared to pre-COVID (1.3cases/year) and COVID (1.5cases/year). There was no difference in the number of cases requiring operation across cohorts (97.8 % overall, p = 0.07).</div></div><div><h3>Conclusion</h3><div>This study revealed a 3.5-fold increase in the mean annual number of mastoiditis cases and a 4.8-fold increase in the mean annual number of cases with complications post-COVID compared to pre-COVID.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112240"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigation-assisted endoscopic U-flap technique and steroid-eluting stent for choanal atresia repair","authors":"Jing-Ying Wen ,&nbsp;Zhe-Zheng Wang ,&nbsp;Fei-Xiong Zhen ,&nbsp;Hong-Tao Zhen","doi":"10.1016/j.ijporl.2025.112217","DOIUrl":"10.1016/j.ijporl.2025.112217","url":null,"abstract":"<div><h3>Objectives</h3><div>Surgery is the only treatment for congenital choanal atresia (CCA). It is crucial to avoid postoperative restenosis or re-occlusion of the neo-choana. This study investigated the efficacy of a navigation-assisted endoscopic endonasal U-flap technique and a bioabsorbable steroid-eluting stent for CCA repair.</div></div><div><h3>Methods</h3><div>A retrospective analysis was performed on 26 patients with CCA, divided into two groups (Group A and Group B). All the patients underwent navigation-assisted endoscopic endonasal resection of the atretic plate. In Group A, a silicone tube was placed to support the neo-choana and retained for 3 weeks, while in Group B, double U-flaps combined with a bioabsorbable steroid-eluting stent were used to support the flaps and the neo-choana. From the 4th week after surgery, the patients were given a budesonide inhalation suspension via transnasal nebulization for 4 weeks. Fiberoptic nasopharyngoscopy was performed at the 4th week, the 6th week, 2 months, 3 months and 6 months after surgery to observe surgical complications and neo-choana patency. The number of cases of restenosis and the number of complications occurring post-operatively were recorded for both groups.</div></div><div><h3>Results</h3><div>The operation success rate in Group A was 63.6 % (7/11), while the operation success rate in Group B was 100 % (15/15). There was a significant difference in the success rate between the two groups (P &lt; 0.05). Patients in Group B exhibited a higher operation success rate, a more comfortable postoperative experience and an absence of complications.</div></div><div><h3>Conclusion</h3><div>Navigation-assisted endoscopic endonasal resection of the atretic plate with two U-shaped mucoperiosteal flaps, a steroid-eluting stent, and post-operative transnasal glucocorticoid nebulization is a minimally invasive, precise and safe technique that is more effective in maintaining the patency of the neo-choana and is less recurrent in patients with CCA.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112217"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143295232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of tonsillectomy on clinical manifestations in Familial Mediterranean fever","authors":"Anwar Abdelatty Ibrahim ,&nbsp;Alsayed Abdulmageed Alsayed ,&nbsp;Mahmoud Abdelrazek Mahmoud ,&nbsp;Attalla Hafez Attalla Hassan ,&nbsp;Ahmad Mahmoud Hamdan","doi":"10.1016/j.ijporl.2025.112231","DOIUrl":"10.1016/j.ijporl.2025.112231","url":null,"abstract":"<div><h3>Purpose</h3><div>Familial Mediterranean fever (FMF) is the most prevalent genetic autoinflammatory disease worldwide. There are several novel advancements in pathophysiology, genetic testing, diagnosis, comorbidities, disease-related damage, and treatment strategies. This study aimed to assess the effect of tonsillectomy on FMF disease severity and activity.</div></div><div><h3>Methods</h3><div>This prospective randomized cohort study was conducted on 43 patients diagnosed with FMF and chronic tonsillitis, who were divided randomly into two groups: Group I, a case group including 23 patients subjected to tonsillectomy and medical treatment using colchicine; Group II, a control group consisting of 20 cases receiving only colchicine. The monthly frequency of the attacks and average duration of the three symptoms, such as fever, abdominal/chest pain, and musculoskeletal pain in days, were evaluated and recorded.</div></div><div><h3>Results</h3><div>A highly significant reduction in the monthly frequency of attacks, duration of fever, abdominal/chest pain, and musculoskeletal pain was observed three months after management in both study groups (p &lt; 0.00001 for all). Evaluation of the values of both groups revealed a significant increase in the degree of change for the duration of fever, abdominal/chest pain in Group I relative to Group II (p = 0.0003 and 0.006 respectively) and a significant increase in the degree of change for musculoskeletal pain in Group II relative to Group I (p = 0.007). Survival analysis showed a nonsignificant difference between the two groups regarding the resolution of fever, abdominal/chest pain, and musculoskeletal pain at 12, 18, and 24 months (p = 0.26, 0.08, and 0.42, respectively)</div></div><div><h3>Conclusion</h3><div>Tonsillectomy operation combined with colchicine resulted in a greater but nonsignificant decrease in the monthly frequency of the FMF attacks and a significant greater decrease in the duration of fever and abdominal/chest pain compared with the use of colchicine alone. Further research is recommended to confirm these results on a larger scale.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112231"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection rate following mandibular distraction with internal and external devices in infants","authors":"Emily R. Disler ,&nbsp;Tania Hassanzadeh ,&nbsp;Corey A. Bryton ,&nbsp;Mark A. Vecchiotti ,&nbsp;Alexander P. Marston ,&nbsp;Andrew R. Scott","doi":"10.1016/j.ijporl.2025.112239","DOIUrl":"10.1016/j.ijporl.2025.112239","url":null,"abstract":"<div><h3>Background</h3><div>Internal and external devices may be utilized in mandibular distraction osteogenesis (MDO) for the correction of symptomatic micrognathia in infants and children.</div></div><div><h3>Purpose</h3><div>To compare the rate and severity of infection between internal and external MDO devices.</div></div><div><h3>Study design, setting, sample</h3><div>Retrospective cohort study utilizing an institutional database of patients who underwent MDO.</div></div><div><h3>Independent variable</h3><div>Use of internal versus external MDO hardware.</div></div><div><h3>Main outcome variables</h3><div>Rate of post-operative surgical site infections (minor and major).</div></div><div><h3>Covariates</h3><div>Patient age, device type, laterality, infection, and treatment were documented.</div></div><div><h3>Analysis</h3><div>Chi-Square and Fisher Exact Tests were used where appropriate for categorical variables and two-tailed T-tests were used for continuous variables. Significance was set at p &lt; 0.05.</div></div><div><h3>Results</h3><div>Between 2010 and 2022, 36 infants (ages 7 days-12 months) underwent bilateral MDO. Thirteen cases utilized internal hardware (n = 26 surgical sites) and 23 cases utilized external hardware (n = 46 surgical sites). Fifteen patients developed post-operative infections (41.7 %), 11 of which were minor infections and 4 were major infections. Seven patients with internal devices (53.8 %) and 8 patients with external devices (34.8 %) developed an infection (p = 0.27). Minor infections occurred in 4 patients with internal hardware (30.8 %) and 7 patients with external hardware (30.4 %; p = 1.00). Major infections occurred in 3 patients with internal hardware (23.1 %) and 1 patient with external hardware (4.3 %; p = 0.25). There were 19 surgical site infections (26.4 %), 14 of which were minor infections and 5 of which were major infections. Ten internal devices (38.6 %) and 9 external devices (19.6 %) were complicated by infection (p = 0.08). Minor infections occurred in 6 internal devices (23.1 %) and 8 external devices (17.4 %; p = 0.56). Major infections occurred in 4 internal devices (15.4 %) and 1 external device (2.2 %; p = 0.05).</div></div><div><h3>Conclusion</h3><div>No significant difference was found in overall postoperative infection rate with internal and external MDO. A lower rate of major infection was observed in external devices.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"189 ","pages":"Article 112239"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}