International journal of pediatric otorhinolaryngology最新文献

{"title":"Evaluation of the relationship between otitis media with effusion and the need for cochleostomy in pediatric cochlear implant patients","authors":"Enver Can Öncül, Yüksel Olgun, Beyazıt Buğra Akbay, Enes Bilgin Türkmenoğlu, Özden Savaş, Erdoğan Özgür, Aslı Çakır Çeti̇n, Enis Alpin Güneri̇","doi":"10.1016/j.ijporl.2025.112575","DOIUrl":"10.1016/j.ijporl.2025.112575","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112575"},"PeriodicalIF":1.3,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the effectiveness of propranolol in treating pediatric airway hemangiomas: A systematic review and meta-analysis","authors":"Lindsey Herberger ,&nbsp;Sydney Gilliam ,&nbsp;Mehrdad Hosseini ,&nbsp;Patrick Bishara ,&nbsp;Soroush Farsi ,&nbsp;Peter Eckard ,&nbsp;Courtney Hunter ,&nbsp;Gresham T. Richter","doi":"10.1016/j.ijporl.2025.112576","DOIUrl":"10.1016/j.ijporl.2025.112576","url":null,"abstract":"<div><h3>Objective</h3><div>Infantile hemangiomas are vascular tumors that present substantial challenges when they involve the airway. This systematic review and meta-analysis aims to explore the safety, efficacy, dosing protocols, and potential adverse effects of propranolol for management of pediatric airway hemangiomas.</div></div><div><h3>Methods</h3><div>Embase, PubMed, Cochrane, and Web of Science were thoroughly searched for articles from their inception up to March 2025, following the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. The quality of the included studies was evaluated using the Newcastle-Ottawa scale (NOS) criteria. In this review paper, successful treatment was defined as achieving full airway clearance to the extent that it no longer posed a threat to the patient's airway as assessed clinically by the treating physician.</div></div><div><h3>Results</h3><div>Of the 835 abstracts screened, 12 articles met inclusion criteria and encompassed 124 patients. The patients’ ages ranged from 2 months to 2.7 years (mean = 1 year). Most patients were female (n = 72, 58 %), and the mean treatment duration was 9.3 months. The pooled data indicated an overall airway clearance rate of 96.3 % (95 %CI 0.908–0.989, I2 = 0 %). Notably, the most reported method of medication delivery was 2 mg/kg/body weight/day divided into 3 oral doses. Furthermore, the pooled complication rate of 3.7 % (95 %CI: 0.010–0.092, I2 = 0 %, n = 4).</div></div><div><h3>Conclusion</h3><div>This meta-analysis strongly supports that propranolol provides a safe and effective approach to managing infantile hemangiomas of the airway. Propranolol can be given at 2 mg/kg/day divided in 3 doses for 6–12 months for 96 % complete clearance rate and limited rebounds after treatment cessation.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112576"},"PeriodicalIF":1.3,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145217341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression levels of MMP-1, MMP-3, and TIMP-1 in pediatric tonsillar tissue: A comparative study of tonsillar hypertrophy and chronic tonsillitis","authors":"Seren Karabiber Cicek ,&nbsp;Gul Acar ,&nbsp;Ilknur Bingul ,&nbsp;Serdal Celik","doi":"10.1016/j.ijporl.2025.112573","DOIUrl":"10.1016/j.ijporl.2025.112573","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study is to investigate the tissue levels of Matrix Metalloproteinase-1 (MMP-1), Matrix Metalloproteinase-3 (MMP-3), and Tissue Inhibitor of Matrix Metalloproteinase-1 (TIMP-1) in cases of chronic tonsillitis and tonsillar hypertrophy, in order to elucidate their mechanisms of action in inflammatory processes.</div></div><div><h3>Materials and methods</h3><div>A total of 72 pediatric patients with an indication for tonsillectomy were included in the study. Of these, 36 patients diagnosed with chronic tonsillitis comprised the chronic tonsillitis (CT)group, while 36 patients diagnosed with tonsillar hypertrophy formed the tonsillar hypertrophy (TH) group. Punch biopsies were obtained from the tonsillar tissue following tonsillectomy in all patients. The samples were homogenized, sonicated, and centrifuged, and the supernatant fluid was analyzed for MMP-1, MMP-3, and TIMP-1 tissue levels using ELISA protocols.</div></div><div><h3>Results</h3><div>In this study, MMP-1, MMP-3 and TIMP-1 levels and the rates of these biomarkers were examined in the chronic tonsillitis and hypertrophic tonsil groups, and no statistically significant difference was found between this two groups. Although a weak positive correlation was noted between age and MMP/TIMP values in both clinical groups, this was not statistically significant. Median values of MMP-1, MMP-3, and TIMP-1 appeared higher in females, but this difference was not statistically significant when compared to males.</div></div><div><h3>Conclusion</h3><div>In this study, tissue levels of MMP-1, MMP-3, and TIMP-1 and their ratios were evaluated in children diagnosed with chronic tonsillitis and tonsillar hypertrophy, with no significant differences detected between the groups. The findings suggest that the MMP/TIMP system maintains a stable balance in tonsillar tissue during childhood and does not appear to distinguish between chronic tonsillitis and tonsillar hypertrophy in clinical practice.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112573"},"PeriodicalIF":1.3,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145155834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiology of acute complicated sinus infections in children following the COVID-19 pandemic","authors":"Sophie Dunmall,&nbsp;John Wood","doi":"10.1016/j.ijporl.2025.112577","DOIUrl":"10.1016/j.ijporl.2025.112577","url":null,"abstract":"<div><h3>Background</h3><div>In subsequent years following the COVID-9 pandemic, clinicians in our centre found a noticeable increase in patients requiring emergency surgery for sinusitis. Consequently this has led to a review comparing the incidence, as well as the microbiology, of acute complicated sinusitis in the pre- and post- COVID period.</div></div><div><h3>Methods</h3><div>A retrospective review of children admitted to the Women's and Children's Hospital in South Australia from 2017 to 2024 with acute complicated sinusitis requiring emergency operative management (functional endoscopic sinus surgery).</div></div><div><h3>Results</h3><div>There were significantly fewer patients undergoing emergency surgery for acute sinusitis in the 3 years preceding the COVID-19 pandemic (9 patients) compared to the 3 years following the start of the pandemic (28 patients) <em>X</em>²(1, <em>N</em> = 37) = 9.22, <em>p</em> = .002394. The most common organisms cultured in both groups were streptococcal and staphylococcal species. The remaining less-common organisms were all cultured in the post-COVID period.</div></div><div><h3>Conclusion</h3><div>In our paediatric centre, more patients are presenting with acute complicated sinusitis requiring emergency surgical management following the COVID-19 pandemic.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112577"},"PeriodicalIF":1.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long Term effectiveness of Solo+ TTD: A single step tympanostomy tube (TT) Delivery device","authors":"Michael E. McCormick ,&nbsp;Diego A. Preciado ,&nbsp;Robert H. Chun ,&nbsp;Brian K. Reilly ,&nbsp;Sophie G. Shay ,&nbsp;Roxanne Link ,&nbsp;Katherine Peterson ,&nbsp;Hengameh K. Behzadpour ,&nbsp;Isabel Baumgartner ,&nbsp;Susan Anderson ,&nbsp;Keith Jansen ,&nbsp;Matija Daniel ,&nbsp;Elizabeth Kane ,&nbsp;Taylor Theriault ,&nbsp;Emily Zetzer ,&nbsp;Laura Davis ,&nbsp;Joseph E. Kerschner","doi":"10.1016/j.ijporl.2025.112567","DOIUrl":"10.1016/j.ijporl.2025.112567","url":null,"abstract":"<div><h3>Background</h3><div>Tympanostomy tube (TT) insertion is typically performed in children in the operating room under general anesthesia. Devices combining equipment and steps in TT insertion, facilitate TT placement and may enable a transition to in-office TT procedures avoiding general anesthesia. This study evaluates the safety and effectiveness of a new TT insertion device, Solo + TTD, with general anesthesia.</div></div><div><h3>Methods</h3><div>Children aged 6 months to 15 years meeting criteria for TT insertion were enrolled in an IRB-approved multicenter single-arm prospective study. TT insertion was performed in the operating room under general anesthesia using the study device. Intraoperative device success, rate of adverse events, function of ear tubes during follow-up (1, 3, 6, 12, 18 and 24 months), and use of additional instrumentation for placement of Solo + TT were evaluated. Interim data through 12 months of follow up are presented in this paper.</div></div><div><h3>Results</h3><div>A total of 59 ears in 30 patients were treated at two sites. The mean age of enrolled children was 2.4 years and 57 % were male. Solo + TT insertion was successful (± use of additional instrumentation) in 57/59 (96.6 %) ears with unsuccessful insertion in two patients due to irregular ear canal anatomy. Two ears required a second Solo + TTD cartridge for successful insertion. There were no serious adverse events related to the device or procedure. Non-serious adverse events at one-month (most common bleeding, otorrhea and blockage) occurred at rates (9/30 patients) similar to standard TT. At 1-month follow up, 96 % (51/53) ears had functioning TT. Through 12-months follow-up, 20 % of TT were extruded (9/44 ears) and 88.6 % of present TT (31/35 ears) were functioning.</div></div><div><h3>Conclusion</h3><div>The Solo + TTD tympanostomy tube device has a high rate of successful TT placement in children under general anesthesia. The device TTs function is similar to traditional TTs and other device TTs out to 1 year. Additional studies evaluating the device in children using topical anesthesia are needed.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112567"},"PeriodicalIF":1.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-implant resting-state connectivity links to post-cochlear implantation auditory/language outcomes in children with congenital sensorineural hearing loss","authors":"Yan Huang ,&nbsp;Rong Yan ,&nbsp;Shuai Yan ,&nbsp;Yuqi Xia ,&nbsp;Caifeng Xia ,&nbsp;Wenwen Su ,&nbsp;Yuyang Wang ,&nbsp;Tianyu Xin ,&nbsp;Zhe Chen ,&nbsp;Zhikai Zhang ,&nbsp;Yuhe Liu","doi":"10.1016/j.ijporl.2025.112574","DOIUrl":"10.1016/j.ijporl.2025.112574","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate whether preoperative resting-state functional connectivity (rs-FC) patterns can predict auditory and language rehabilitation outcomes following cochlear implantation (CI) in children with severe-to-profound congenital sensorineural hearing loss (CSHL), thereby informing individualized prognostic and therapeutic strategies.</div></div><div><h3>Methods</h3><div>Twenty pediatric patients with bilateral CSHL underwent resting-state functional magnetic resonance imaging (rs-fMRI) prior to CI during the sensitive period of auditory cortex development. The Infant-Toddler Meaningful Auditory Integration Scale/Meaningful Auditory Integration Scale (IT-MAIS/MAIS) was used to assess the postoperative auditory and language abilities at five time points over 12 months. Multiple linear regression analyses were performed to evaluate the relationship between pre-CI rs-FC and behavioral outcomes. A predictive model was developed based on significant rs-FC features.</div></div><div><h3>Results</h3><div>Significant improvements in the IT-MAIS/MAIS scores were observed at each follow-up point post-implantation (p &lt; 0.0001). Preoperative rs-FC, involving the prefrontal cortex, occipitoparietal regions, and subcortical structures, strongly correlated with baseline and longitudinal auditory performance. FCs between specific brain regions, including the orbital frontal cortex, angular gyrus, and Heschl's gyrus, were associated with different phases of postoperative improvement. The rs-FC-based predictive model demonstrated high explanatory power for post-CI outcomes (R² values up to 0.82).</div></div><div><h3>Conclusion</h3><div>Resting-state brain connectivity patterns pre-CI can serve as reliable neuroimaging biomarkers for predicting auditory and language rehabilitation outcomes in young children with CSHL. These findings provide a neurofunctional basis for early prognostication and support the development of personalized rehabilitation protocols guided by preoperative brain imaging.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112574"},"PeriodicalIF":1.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145118807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric facial trauma: how social determinants of health impact injury patterns","authors":"Anna N. Berezovsky ,&nbsp;Abigail B. Thomas ,&nbsp;Jazzmyne A. Adams ,&nbsp;Jake Luo ,&nbsp;David R. Friedland ,&nbsp;Sophie G. Shay","doi":"10.1016/j.ijporl.2025.112572","DOIUrl":"10.1016/j.ijporl.2025.112572","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate social determinants of health and pediatric facial trauma and characterize pediatric facial trauma.</div></div><div><h3>Study design</h3><div>Retrospective observational cohort.</div></div><div><h3>Setting</h3><div>Tertiary pediatric hospital.</div></div><div><h3>Methods</h3><div>Review of patients &lt;18 years seen for facial trauma from 2016 to 2022.</div></div><div><h3>Results</h3><div>10,227 patients presented with facial trauma (median age 4.97 years, 62.2 % male). Lacerations represented 83.3 % (n = 8523) of facial traumas and were found in younger patients (median age 4.72 years), followed by bony trauma (15.0 %, n = 1531) which was found in older patients (median age 10.6 years). Mechanism of injury was available for 5523 patients, with 72.1 % due to motor vehicle collision (MVC, n = 3981), 18.2 % due to dog bite (n = 1007), and 4.85 % from gunshot wounds (GSW, n = 268). MVCs were positively associated with female sex (OR 1.15, p &lt; 0.001), Black race (OR 1.35, p &lt; 0.001), and older age (p &lt; 0.001). Dog bites were positively associated with White race (OR 3.77, p &lt; 0.001), Hispanic/Latino ethnicity (OR 1.22, p &lt; 0.001), and younger age (p &lt; 0.001). GSW patients were older (p &lt; 0.001) and were three times more likely to be male (OR 3.15, p &lt; 0.001) and Black (OR 2.87, p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>To our knowledge, the present study includes the largest single-institution review of pediatric facial trauma and highlights differences from adult populations. The most common mechanisms of injury were MVC, dog bites and GSWs. Age, race, ethnicity and insurance played significant, but varying roles in patterns of trauma. The sociodemographic factors associated with facial trauma are important considerations for public health efforts in reducing risk for pediatric trauma.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112572"},"PeriodicalIF":1.3,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145106805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of concurrent pharyngoplasty with adenotonsillectomy to treat pediatric obstructive sleep apnea","authors":"Sweeya V. Raj ,&nbsp;Kelly L. Vittetoe ,&nbsp;Emily L. Mace ,&nbsp;Daniel Larson ,&nbsp;Amy S. Whigham","doi":"10.1016/j.ijporl.2025.112571","DOIUrl":"10.1016/j.ijporl.2025.112571","url":null,"abstract":"<div><h3>Objective</h3><div>This study assesses whether surgical procedures to address pharyngeal anatomy performed concurrently with adenotonsillectomy (AT) lead to improved postoperative polysomnogram (PSG) outcomes in children with obstructive sleep apnea (OSA) compared to AT alone.</div></div><div><h3>Study design/setting</h3><div>This is a retrospective cohort study conducted at a tertiary care children's hospital in the southeastern United States.</div></div><div><h3>Methods</h3><div>Patients were identified using Current Procedural Terminology (CPT) codes for pharyngoplasty and AT. Retrospective chart review was conducted to obtain clinical data. Patients were matched by age, body mass index (BMI), and preoperative apnea hypopnea index (AHI) to children who underwent AT alone.</div></div><div><h3>Results</h3><div>Forty-six children who underwent AT with concomitant pharyngoplasty were identified along with 187 patients who underwent AT alone. Age, BMI, and preoperative AHI were significantly higher in the pharyngoplasty + AT group. The pharyngoplasty + AT group demonstrated significantly greater improvement in AHI, REM AHI, and obstructive AHI (oAHI) postoperatively; however, multivariable regression showed that BMI predicted postoperative change in AHI. Twenty children in each group were therefore matched by age, BMI, and preoperative AHI. Subsequent analysis of matched cases revealed no significant difference in surgical outcomes between groups.</div></div><div><h3>Conclusion</h3><div>After controlling for age, BMI, and preoperative AHI, there was no difference between AT with concurrent pharyngoplasty and AT alone with respect to change in AHI or oxygen saturation nadir postoperatively. Ultimately, children who undergo pharyngoplasty in combination with AT are a clinically distinct group, and further randomized controlled trials within this population are necessary to define the role of pharyngoplasty concurrent with AT.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112571"},"PeriodicalIF":1.3,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial and ethnic representation in pediatric rhinitis trials: Analysis and insights","authors":"Hardeep S. Tiwana ,&nbsp;Elizabeth M. Puyo ,&nbsp;Jonathan M. Carnino ,&nbsp;Iman S. Iqbal ,&nbsp;Dean G. Kennedy ,&nbsp;Jessica R. Levi","doi":"10.1016/j.ijporl.2025.112570","DOIUrl":"10.1016/j.ijporl.2025.112570","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112570"},"PeriodicalIF":1.3,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic endonasal transsphenoidal surgery in children: Necker - Enfants Malades Hospital experience","authors":"Léa Fath ,&nbsp;François Simon ,&nbsp;Hakim Benkhatar ,&nbsp;Françoise Denoyelle ,&nbsp;Stéphanie Puget ,&nbsp;Vincent Couloigner ,&nbsp;Kevin Beccaria","doi":"10.1016/j.ijporl.2025.112563","DOIUrl":"10.1016/j.ijporl.2025.112563","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to analyze a large series of children treated transsphenoidally by both neurosurgical and Ear Nose Throat (ENT) surgical teams for sellar or parasellar lesions.</div></div><div><h3>Study design</h3><div>It was an observational study in a French pediatric tertiary referral center.</div></div><div><h3>Setting</h3><div>The patients included were under 18 years of age at time of surgery, had no open neurosurgical history, and required endoscopic endonasal transsphenoidal surgery.</div></div><div><h3>Methods</h3><div>All endoscopic endonasal procedures were conducted by both neurosurgeon and ENT surgeon alternating as first operator according to the different phases of the operation. Data collection was carried out using the Dr Warehouse data platform.</div></div><div><h3>Results</h3><div>From 2005 to 2018, 75 children (41 boys and 34 girls) were included retrospectively. The average age at the time of surgery was 10 years [range: 3–17]. One hundred twenty-three procedures were performed: 75 primary tumour resections (17 partial (22.7 %), 35 (46.7 %) near total and 18 (24 %) total resections), 5 biopsies, 45 revision procedures for tumour recurrences or residuals and 3 revision procedures for post-operative cerebrospinal fluid (CSF) leaks. 10 patients (13.3 %) had post-operative CSF leaks and 5 patients (6.7 %) developed meningitis without any sequelae. No death occurred.</div></div><div><h3>Conclusion</h3><div>The minimally invasive transsphenoidal endonasal surgery is feasible in the pediatric population, allows excision of sellar and parasellar lesions in children without major complications, and avoids open technique comorbidities.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112563"},"PeriodicalIF":1.3,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145106803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}