International journal of pediatric otorhinolaryngology最新文献

{"title":"Impact of age and allergen type on sensitization changes in children with chronic rhinitis.","authors":"Sucheera Nokkaew, Wanlapa Jotikasthira, Potjanee Kiewngam, Adithep Sawatchai, Watcharoot Kanchongkittiphon, Wiparat Manuyakorn","doi":"10.1016/j.ijporl.2025.112508","DOIUrl":"10.1016/j.ijporl.2025.112508","url":null,"abstract":"<p><strong>Background: </strong>Aeroallergen sensitization evaluation aids in diagnosing and managing chronic rhinitis.</p><p><strong>Objective: </strong>To investigate changes in allergen sensitization over time in children with rhinitis.</p><p><strong>Methods: </strong>Children with chronic rhinitis who underwent aeroallergen skin prick tests (SPT) between 2009 and 2019 were re-evaluated with a second SPT between 2022 and 2024. Sensitization changes were assessed by comparing initial and re-evaluation SPT results. A negative converter was defined as a previously positive test that became negative.</p><p><strong>Results: </strong>Among 300 children (mean age 11.5 years), positive SPT rates increased from 71.3 % to 83.7 % (p < 0.001). House dust mites (HDM) were the most common sensitization (77 %), followed by cockroaches (24 %). Sensitization patterns changed in 56.7 % of children. HDM sensitization increased across all age groups, while cat sensitization rose significantly in those initially tested before age 5. Negative conversion rates varied by allergen, highest for Careless Weed (85.7 %) and lowest for HDM (1.52 %). Children who became negative converters for Bermuda grass had smaller initial wheal sizes than those who remained positive (3 mm vs. 5.8 mm, p = 0.003).</p><p><strong>Conclusion: </strong>Allergen sensitization patterns evolve over time, influenced by allergen type and patient age. Repeat testing may be necessary, especially for children with uncontrolled rhinitis.</p>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"112508"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral vestibular hypofunction in children.","authors":"E Loos, M Gerdsen, M Hazen, S L Cushing, K A Gordon, A Perez-Fornos, N Verhaert, C Desloovere, R Van de Berg, J Widdershoven","doi":"10.1016/j.ijporl.2025.112506","DOIUrl":"10.1016/j.ijporl.2025.112506","url":null,"abstract":"<p><strong>Background: </strong>Vestibular hypofunction in children can lead to frequent falls and delayed motor development. Especially children with bilateral vestibular hypofunction (BVH) are most at risk for developing symptoms. These children might benefit from future therapies, like vestibular implants, to restore their vestibular system. This study aimed to describe the prevalence, etiology, motor development, and hearing status of pediatric patients with BVH.</p><p><strong>Methods: </strong>A multicenter retrospective chart review of 492 children with sensorineural hearing loss was performed. Children with at least one bilaterally abnormal vestibular test were defined as having a BVH.</p><p><strong>Results: </strong>BVH was found in 23 % of the screened children. Especially children with syndromic hearing loss like Usher, CHARGE, or Waardenburg syndrome and infectious etiologies like congenital CMV and meningitis, were prone to have BVH on all performed tests. Children with BVH had a high percentage of motor developmental delay (81 %), especially if all tests were abnormal on both sides (97 %).</p><p><strong>Conclusion: </strong>It is recommended to perform vestibular screening in children with sensorineural hearing loss, as BVH is prevalent. BVH has a very high risk of causing a delay in motor development. Especially in children with BVH on all vestibular tests, motor development is impaired. Those children might benefit from vestibular implants in the future.</p>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"196 ","pages":"112506"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2023 aerodigestive Society meeting: A multidisciplinary literature year in review","authors":"Sarah C. Hofman Deyoung ,&nbsp;Deborah R. Liptzin ,&nbsp;Nancy M. Bauman ,&nbsp;Cheryl Hersh ,&nbsp;Kaalan E. Johnson ,&nbsp;Matthew T. Brigger ,&nbsp;Amornluck Krasaelap","doi":"10.1016/j.ijporl.2025.112539","DOIUrl":"10.1016/j.ijporl.2025.112539","url":null,"abstract":"<div><div>The 2023 Aerodigestive Society meeting aimed to emphasize the importance of a multidisciplinary approach in managing aerodigestive disorders that affect the lungs, upper airway, and gastrointestinal tract in children. This approach necessitates the collaboration of multiple specialists and allied healthcare professionals. A collaborative approach to aerodigestive disorders is a young field with many opportunities for investigation of disease understanding and treatment approaches. This narrative review synthesizes key studies presented during the \"Year in Review\" session at the meeting, representing diverse specialties including otolaryngology, pulmonology, gastroenterology, speech-language pathology, occupational therapy, and nutrition, emphasizing the collaborative effort essential for enhanced patient outcomes in this complex field.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112539"},"PeriodicalIF":1.3,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear implantation in patients with keratitis-ichthyosis-deafness syndrome: A systematic review","authors":"Alexa N. Pearce,&nbsp;Soroush Farsi,&nbsp;Carissa C. Saadi,&nbsp;Alaina D. Baggett,&nbsp;John L. Dornhoffer,&nbsp;Robert A. Saadi","doi":"10.1016/j.ijporl.2025.112530","DOIUrl":"10.1016/j.ijporl.2025.112530","url":null,"abstract":"<div><h3>Objective</h3><div>Keratitis-Ichthyosis-Deafness (KID) syndrome is a rare congenital disorder characterized by vascularizing keratitis, hyperkeratosis, and profound sensorineural hearing loss. Skin debris and chronic otitis may render conventional hearing aids ineffective, and visual impairment may preclude use of sign language. This study assesses the unique challenges and outcomes associated with cochlear implantation (CI) in this patient population.</div></div><div><h3>Data sources</h3><div>Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol, PubMed, Web of Science, and Embase were queried from each database's inception to present day (November 2024) for articles describing CI outcomes in KID syndrome patients.</div></div><div><h3>Review methods</h3><div>Studies were examined for participant demographics, age at time of CI, lateralization of CI, previous hearing aid use, CI model, and follow-up length. A qualitative synthesis of post-operative complications and long-term outcomes was employed for all studies.</div></div><div><h3>Results</h3><div>Of 224 abstracts initially identified, 9 met the inclusion criteria, comprising 13 patients and 17 ears. Notable complications included postoperative infection (30.8 %, n = 4) and superficial wound dehiscence (15.4 %; n = 2). One patient required revision surgery with local tissue rearrangement, and one other patient was offered revision due to complications but refused. Ten ears (58.8 %) had very limited or no complications after CI. The average hearing improvement was 45 dB (28 dB–60 dB).</div></div><div><h3>Conclusion</h3><div>CI in patients with KID syndrome presents distinctive challenges but is a safe and effective treatment option. Close monitoring of the postoperative incision is advised to expediently manage any wound healing issues, but long-term results appear to be successful in most cases.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112530"},"PeriodicalIF":1.3,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the protective and therapeutic effects of coenzyme Q10 on acoustic trauma-induced hearing loss in rats","authors":"Togay Müderris ,&nbsp;Oben Yıldırım ,&nbsp;Tankut Uzun ,&nbsp;Serpil Mungan Durankaya ,&nbsp;Nesibe Kahraman Çetin ,&nbsp;Günay Kırkım ,&nbsp;Osman Yılmaz","doi":"10.1016/j.ijporl.2025.112534","DOIUrl":"10.1016/j.ijporl.2025.112534","url":null,"abstract":"<div><h3>Background</h3><div>Acoustic trauma is a process in which the sound energy coming into the ear is so high that it causes hearing loss. Although various treatments have entered clinical practice today, studies on the prevention and treatment of acoustic trauma continue. In our study, we investigated the protective and therapeutic effects of CoQ10 in rats with hearing loss due to acoustic trauma.</div></div><div><h3>Materials and method</h3><div>35 Wistar-type Albino rats were used in the study. The rats were randomly divided into five equal groups. The groups are the acoustic trauma group (group 1), the ethanol (solvent of CoQ10) group (group 2), the group given CoQ10 treatment after acoustic trauma (group 3), the control group (group 4), and the group given CoQ10 both before and after acoustic trauma (group 5). At the beginning of the experiment, after CoQ10 treatment and after acoustic trauma, the ABR test was performed in accordance with the experimental plan. At the end of the treatment, ABR was performed on all subjects and the subjects were sacrificed and their bilateral cochleas were excised. Cochleas were examined histopathologically.</div></div><div><h3>Results</h3><div>Hearing thresholds in the ABR performed on the last day of the study of rats that received CoQ10 after acoustic trauma and those that received CoQ10 both before and after acoustic trauma were significantly better than the measurements on the first day after acoustic trauma(p &lt; 0.05). In histopathological examination, it was observed that the rats in group 5 had more outer hair cells than those in groups 1 and 3. Marginal cell loss in the stria vascularis was less, and nuclear degeneration in the spiral ganglia was less.</div></div><div><h3>Conclusion</h3><div>In our study, it was determined that CoQ10 had both a protective and therapeutic effect on hearing loss due to acoustic trauma. Better ABR results were obtained in the group given CoQ10 both before and after acoustic trauma.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112534"},"PeriodicalIF":1.3,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Neurodevelopmental impact of congenital cytomegalovirus in children with cochlear Implants” [Int. J. Pediatr. Otorhinolaryngol. 180 (2024) 111939]","authors":"Marie Reynders ,&nbsp;Kristin Kerkhofs ,&nbsp;Annabel Heyndrickx ,&nbsp;Kirana Noerens ,&nbsp;Ina Foulon","doi":"10.1016/j.ijporl.2025.112438","DOIUrl":"10.1016/j.ijporl.2025.112438","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112438"},"PeriodicalIF":1.3,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualizing natural sleep state during nasolaryngoscopy in infants: A feasibility study","authors":"Vanessa Helou ,&nbsp;Nicholas Oberlies ,&nbsp;Amber D. Shaffer ,&nbsp;Rachel Whelan ,&nbsp;Sanjay R. Patel ,&nbsp;Noel Jabbour","doi":"10.1016/j.ijporl.2025.112538","DOIUrl":"10.1016/j.ijporl.2025.112538","url":null,"abstract":"<div><h3>Introduction</h3><div>Otolaryngology consultation for infant airway obstruction is common, with nasolaryngoscopy being the primary diagnostic tool. However, traditional awake nasolaryngoscopy is often limited by infant crying and brief examinations. A more detailed drug-induced sleep endoscopy requires anesthesia and operating room resources. This study explores Time-Induced Sleep Endoscopy (TISE) as a relatively brief, non-invasive alternative for evaluating sleep-related airway dynamics in infants.</div></div><div><h3>Methods</h3><div>This prospective study enrolled infants under three months of age at UPMC Children's Hospital of Pittsburgh. Hospitalized infants requiring bedside flexible nasolaryngoscopy for airway evaluation were eligible. A flexible nasolaryngoscope was inserted nasally and left in place until the infant fell asleep with a 5-min cut-off. Endoscopic videos were scored for airway obstruction while awake and asleep by two pediatric otolaryngologists using the Sleep Endoscopy Rating Scale. Demographics and time to sleep were recorded. Logistic regression examined factors associated with successful TISE. Inter-rater reliability was assessed using Cohen's Kappa.</div></div><div><h3>Results</h3><div>Among 19 infants (median post-menstrual age at evaluation: 40.3 weeks, range: 37.1–51.5), TISE was successful in 11 (57.9 %), with an average time to sleep of 3.1 min. Infants younger than three weeks were eight times more likely to fall asleep compared to older infants (OR = 8.00, 95 % CI: 1.00–63.96, <em>p=.048</em>). Compared to awake endoscopy, TISE revealed higher frequency of airway obstruction, particularly for hypopharyngeal obstruction (100 % compared to 18 %, <em>p=.004</em>). Inter-rater reliability was moderate for awake endoscopy (κ = 0.55) and fair for TISE (κ = 0.38).</div></div><div><h3>Conclusion</h3><div>TISE can allow for visualization of sleep-related airway obstruction in some infants. Further validation is needed for broader use.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112538"},"PeriodicalIF":1.3,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144906997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental sustainability in pediatric otolaryngology: An international survey of operating room practice patterns","authors":"Nick Teller ,&nbsp;Kalpesh Hathi ,&nbsp;Claire A. Wilson ,&nbsp;Jacob Davidson ,&nbsp;Anthony De Luca ,&nbsp;Neil K. Chadha ,&nbsp;Sohit Kanotra ,&nbsp;Eric Levi ,&nbsp;Mat Daniel ,&nbsp;Scott M. Rickert ,&nbsp;Thomas Schrepfer ,&nbsp;Niall Jefferson ,&nbsp;Julie Strychowsky","doi":"10.1016/j.ijporl.2025.112532","DOIUrl":"10.1016/j.ijporl.2025.112532","url":null,"abstract":"<div><h3>Objectives</h3><div>The primary objective of this study was to evaluate international practice patterns related to environmental sustainability in pediatric otolaryngology ORs, with a focus on the use of single-use versus reusable supplies.</div></div><div><h3>Methods</h3><div>An electronic survey was distributed using REDCap to members of an international pediatric otolaryngology WhatsApp group (n = 324). The survey included multiple-choice, Likert-scale, and open-ended questions regarding drape, gown, and glove usage for adenotonsillectomy, ear tube insertion, and laryngoscopy/bronchoscopy procedures, and broader sustainability practices including barriers and enablers.</div></div><div><h3>Results</h3><div>Response rate was 16.0 % (n = 52/324). Respondents were from North America (30.8 %), Europe (25.0 %), Australia/New Zealand (23.1 %), Asia (15.4 %), South America (3.8 %), and Africa (1.9 %). For adenotonsillectomy 61.5 % reported using single-use patient drapes, 61.5 % use single-use table drapes, and 44.2 % use single-use gowns. For ear tube insertions, single-use table drapes (53.8 %) were most frequently reported; single-use patient drapes (38.4 %) and gowns (21.2 %) were less common. For laryngoscopy/bronchoscopy, the majority did not use patient drapes (31.4 %) or gowns (32.7 %), while 62.8 % use single-use table drapes. Top barriers to improving sustainability in the OR were cost (51.9 %) and infection prevention and control (IPAC) practices (44.2 %). Enablers included sufficient technological (46.2 %) and financial (36.6 %) resources, dedicated policies (30.8 %), and supportive leadership (34.6 %).</div></div><div><h3>Conclusion</h3><div>There remains a strong reliance on single-use materials in pediatric otolaryngology ORs globally. Cost, IPAC, education, and leadership are important considerations in sustainability efforts. These findings identify actionable targets for waste reduction and support the need for specialty-specific sustainability interventions.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112532"},"PeriodicalIF":1.3,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144912545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-component and multi-frequency tympanometry: a comparison between cochlear implanted ear and non-implanted ear","authors":"Palani Saravanan ,&nbsp;Megha ,&nbsp;Pooja Venkatesh","doi":"10.1016/j.ijporl.2025.112537","DOIUrl":"10.1016/j.ijporl.2025.112537","url":null,"abstract":"<div><h3>Objectives</h3><div>Cochlear implant (CI) surgery may alter middle ear structure and function, potentially affecting the measurement of the electrically evoked stapedius reflex threshold (eSRT). This study aimed to investigate such alterations using multi-component and multi-frequency tympanometry. Specific objectives were to compare tympanometric findings, multi-component tympanogram patterns, and frequency-dependent changes in admittance (ΔY), susceptance (ΔB), conductance (ΔG), and phase angle (Δθ) between implanted and contralateral non-implanted ears.</div></div><div><h3>Methods</h3><div>Twenty-two paediatric participants with unilateral CI (Cochlear Nucleus CI422 with CP802 processor), aged 3.5–7 years, were included. Tympanometric assessments were performed using probe tones of 226 Hz, 678 Hz, and 1000 Hz to record admittance, susceptance, and conductance. Multi-component tympanograms were classified according to the Vanhuyse model. Multi-frequency tympanometry was conducted using the sweep-frequency method (250–2000 Hz, in 50 Hz steps). Parameters ΔY, ΔB, ΔG, and Δθ across frequencies were compared between implanted and non-implanted ears.</div></div><div><h3>Results</h3><div>The implanted ears showed significant reductions in static admittance and elevations in resonant frequency compared to non-implanted ears (p &lt; 0.05). At 1000 Hz, 5 of 22 implanted ears (22.7 %) demonstrated the 3B1G pattern, compared with 11 of 22 (50 %) non-implanted ears. Frequency-dependent decreases in ΔY, ΔB, ΔG, and Δθ were also significant in implanted ears (p &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>CI surgery is associated with frequency-dependent changes in the implanted ear, indicating altered mechano-acoustical properties of the middle ear and increased stiffness. These changes may influence clinical procedures, particularly eSRT measurement.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112537"},"PeriodicalIF":1.3,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144906996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and patterns of dog bite-related head and neck injuries: A NEISS database study","authors":"Sharwani Kota ,&nbsp;Christina Zhu ,&nbsp;Sneha Banerjee ,&nbsp;Earl Harley","doi":"10.1016/j.ijporl.2025.112535","DOIUrl":"10.1016/j.ijporl.2025.112535","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112535"},"PeriodicalIF":1.3,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}