Endoscopic endonasal transsphenoidal surgery in children: Necker - Enfants Malades Hospital experience

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology Pub Date : 2025-09-17 DOI:10.1016/j.ijporl.2025.112563

Léa Fath , François Simon , Hakim Benkhatar , Françoise Denoyelle , Stéphanie Puget , Vincent Couloigner , Kevin Beccaria

{"title":"Endoscopic endonasal transsphenoidal surgery in children: Necker - Enfants Malades Hospital experience","authors":"Léa Fath , François Simon , Hakim Benkhatar , Françoise Denoyelle , Stéphanie Puget , Vincent Couloigner , Kevin Beccaria","doi":"10.1016/j.ijporl.2025.112563","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to analyze a large series of children treated transsphenoidally by both neurosurgical and Ear Nose Throat (ENT) surgical teams for sellar or parasellar lesions.</div></div><div><h3>Study design</h3><div>It was an observational study in a French pediatric tertiary referral center.</div></div><div><h3>Setting</h3><div>The patients included were under 18 years of age at time of surgery, had no open neurosurgical history, and required endoscopic endonasal transsphenoidal surgery.</div></div><div><h3>Methods</h3><div>All endoscopic endonasal procedures were conducted by both neurosurgeon and ENT surgeon alternating as first operator according to the different phases of the operation. Data collection was carried out using the Dr Warehouse data platform.</div></div><div><h3>Results</h3><div>From 2005 to 2018, 75 children (41 boys and 34 girls) were included retrospectively. The average age at the time of surgery was 10 years [range: 3–17]. One hundred twenty-three procedures were performed: 75 primary tumour resections (17 partial (22.7 %), 35 (46.7 %) near total and 18 (24 %) total resections), 5 biopsies, 45 revision procedures for tumour recurrences or residuals and 3 revision procedures for post-operative cerebrospinal fluid (CSF) leaks. 10 patients (13.3 %) had post-operative CSF leaks and 5 patients (6.7 %) developed meningitis without any sequelae. No death occurred.</div></div><div><h3>Conclusion</h3><div>The minimally invasive transsphenoidal endonasal surgery is feasible in the pediatric population, allows excision of sellar and parasellar lesions in children without major complications, and avoids open technique comorbidities.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"198 ","pages":"Article 112563"},"PeriodicalIF":1.3000,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of pediatric otorhinolaryngology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165587625003519","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

This study aimed to analyze a large series of children treated transsphenoidally by both neurosurgical and Ear Nose Throat (ENT) surgical teams for sellar or parasellar lesions.

Study design

It was an observational study in a French pediatric tertiary referral center.

Setting

The patients included were under 18 years of age at time of surgery, had no open neurosurgical history, and required endoscopic endonasal transsphenoidal surgery.

Methods

All endoscopic endonasal procedures were conducted by both neurosurgeon and ENT surgeon alternating as first operator according to the different phases of the operation. Data collection was carried out using the Dr Warehouse data platform.

Results

From 2005 to 2018, 75 children (41 boys and 34 girls) were included retrospectively. The average age at the time of surgery was 10 years [range: 3–17]. One hundred twenty-three procedures were performed: 75 primary tumour resections (17 partial (22.7 %), 35 (46.7 %) near total and 18 (24 %) total resections), 5 biopsies, 45 revision procedures for tumour recurrences or residuals and 3 revision procedures for post-operative cerebrospinal fluid (CSF) leaks. 10 patients (13.3 %) had post-operative CSF leaks and 5 patients (6.7 %) developed meningitis without any sequelae. No death occurred.

Conclusion

The minimally invasive transsphenoidal endonasal surgery is feasible in the pediatric population, allows excision of sellar and parasellar lesions in children without major complications, and avoids open technique comorbidities.

查看原文本刊更多论文

儿童鼻内经蝶窦手术：Necker - enants Malades医院的经验

目的本研究旨在分析由神经外科和耳鼻喉外科（ENT）团队经蝶窦治疗鞍或鞍旁病变的大量儿童病例。研究设计：这是一项在法国儿科三级转诊中心进行的观察性研究。纳入的患者在手术时年龄在18岁以下，没有开放的神经外科病史，需要内镜下经鼻蝶窦手术。方法所有鼻内镜手术均由神经外科医生和耳鼻喉外科医生根据手术的不同阶段轮流担任第一手术者。数据收集使用Dr Warehouse数据平台进行。结果2005年至2018年，回顾性纳入75例儿童（41例男孩，34例女孩）。手术时平均年龄为10岁[范围：3-17岁]。共进行了123例手术：75例原发性肿瘤切除（17例部分切除（22.7%），35例（46.7%）接近全部切除，18例（24%）全部切除），5例活检，45例肿瘤复发或残留翻修手术，3例术后脑脊液（CSF）泄漏翻修手术。术后脑脊液渗漏10例（13.3%），并发脑膜炎5例（6.7%），无任何后遗症。无人员死亡。结论经蝶窦鼻内微创手术在儿童人群中是可行的，可以切除儿童鞍旁病变，无重大并发症，避免了开放技术的合并症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International journal of pediatric otorhinolaryngology 医学-耳鼻喉科学

CiteScore

3.20

自引率

6.70%

发文量

276

审稿时长

62 days

期刊介绍： The purpose of the International Journal of Pediatric Otorhinolaryngology is to concentrate and disseminate information concerning prevention, cure and care of otorhinolaryngological disorders in infants and children due to developmental, degenerative, infectious, neoplastic, traumatic, social, psychiatric and economic causes. The Journal provides a medium for clinical and basic contributions in all of the areas of pediatric otorhinolaryngology. This includes medical and surgical otology, bronchoesophagology, laryngology, rhinology, diseases of the head and neck, and disorders of communication, including voice, speech and language disorders.