Philippe Reymond, Mayra Contreras, Olivier Brina, Trent Langston, Naomi Chesler, Waleed Brinjikji, John Wainwright, Paolo Machi
{"title":"Accelerated aspiration with Q™ catheter: An <i>in vitro</i> study.","authors":"Philippe Reymond, Mayra Contreras, Olivier Brina, Trent Langston, Naomi Chesler, Waleed Brinjikji, John Wainwright, Paolo Machi","doi":"10.1177/15910199241273974","DOIUrl":"10.1177/15910199241273974","url":null,"abstract":"<p><p>Background and PurposeThrombectomy in distal, medium vessels is a topic of increasing interest. To date, there are few <i>in vitro</i> studies focused on performance of ≤5F catheters in medium vessels. The purpose of this study is to compare the performance of the 3F, 4F, and 5F MIVI Neuroscience Q Catheters versus Penumbra 3F, 4F, and MicroVention Sofia 5F Catheters.MethodsUsing <i>in vitro</i> methods, we assessed and compared the following parameters: aspiration flow rates, clot uncorking forces, impulse, and clot ingestion. For flow rate, each aspiration catheter was immersed in a cylindrical container. Flow rate at one second was used to calculate impulse. For clot uncorking force, the force required to disengage a catheter from a simulated clot was recorded. For ingestion, we measured time to ingest soft and medium stiffness synthetic clots.ResultsThe measured flow rates without a stent retriever for the Q3, Q4, and Q5 catheters were 3.54 ml/s, 5.32 ml/s, and 6.87 ml/s. The measured flow rates without a stent retriever for the 3MAX, 4MAX, and 5F Sofia were 1.46 ml/s, 2.56 ml/s, and 1.73 ml/s. The impulse calculated for one second was 26 mNs for Q5 vs 9 mNs for Sofia 5, 35 mNs for Q4 vs 15 mNs for 4Max< and 35 mNs for Q3 vs 9 mNs for 3Max. The average system ingestion for Q was significantly faster than the competitive catheters.ConclusionsThe Q catheters demonstrated higher flow rates, higher uncorking force, and faster complete clot ingestion than competitive catheters.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2604-2609"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emre Can Çelebioğlu, Guilherme Dabus, Sena Bozer Uludağ, Ömer Arda Çetinkaya, Sena Ünal, Uğur Bengisun, Sadık Eryılmaz, Mine Hayriye Sorgun, İhsan Doğan, Şermin Atmaca, Evren Özçınar, Başak Ceyda Meço, Mustafa Bahadır İnan, Canan Togay Işıkay, Ahmet Rüçhan Akar, İskender Alaçayır, Sadık Bilgiç
{"title":"Carotid artery stenting for symptomatic carotid near occlusions: Feasibility, safety and outcome analysis.","authors":"Emre Can Çelebioğlu, Guilherme Dabus, Sena Bozer Uludağ, Ömer Arda Çetinkaya, Sena Ünal, Uğur Bengisun, Sadık Eryılmaz, Mine Hayriye Sorgun, İhsan Doğan, Şermin Atmaca, Evren Özçınar, Başak Ceyda Meço, Mustafa Bahadır İnan, Canan Togay Işıkay, Ahmet Rüçhan Akar, İskender Alaçayır, Sadık Bilgiç","doi":"10.1177/15910199241292387","DOIUrl":"10.1177/15910199241292387","url":null,"abstract":"<p><p>IntroductionExtracranial internal carotid stenosis (EICS) is a well-established cause of stroke. Carotid near-occlusion (CNO), either distally collapsed or not, is a rare sub-type of EICS with conflicting data regarding the necessity for treatment. The aim of this study is to evaluate the results of carotid artery stenting (CAS) for patients with symptomatic CNOs.Material and methodsInstitutional review board (I06-420-23) approval was obtained for this retrospective study. Consecutive data from January 2019 to January 2023 was obtained. Sixty-five patients underwent 66 procedures for symptomatic CNOs. Diagnosis of CNOs were made with DSA images. Treatment decisions were made by a multidisciplinary team. Patient data including age, gender, clinical presentation, affected side, complications (initial/ follow-up), and pre and post mRS scores were recorded and analyzed.ResultsThere were 22 female and 43 male patients with symptomatic CNOs (mean age: 71.52 ± 9.32 years). The mean time from symptom-to-treatment was 3.91 weeks ± 3.74 weeks (ranging from 0 to 20 weeks). There were eight events recorded in the 30 days period after CAS; five (7.7%) were cerebral hyperperfusion syndrome (one causing haemorrhage) and three (4.5%) ischemic complications. Permanent neurologic deficit rate was 6% and 61 patients (94%) mRS scores were unchanged during last follow-up. Mean follow-up period was 22.94 ± 16.67 months (ranging from 0.5 to 60 months).ConclusionOur study demonstrated that in the complex population of patients with symptomatic CNOs, CAS is a feasible option with acceptable rate of permanent neurologic deficits. Further studies are needed to assess its safety and long-term efficacy.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2490-2496"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rikke Puggaard, Nicolaj Grønbæk Laugesen, Klaus Hansen, Andreas H Brandt, Trine Stavngaard, Thomas C Truelsen
{"title":"Outcome and safety of mechanical thrombectomy in patients with acute ischemic stroke due to internal carotid artery dissection.","authors":"Rikke Puggaard, Nicolaj Grønbæk Laugesen, Klaus Hansen, Andreas H Brandt, Trine Stavngaard, Thomas C Truelsen","doi":"10.1177/15910199241261753","DOIUrl":"10.1177/15910199241261753","url":null,"abstract":"<p><p>BackgroundMechanical thrombectomy (MT) in patients with symptoms of acute ischemic stroke (AIS) due to internal carotid artery dissection (ICAD) remains controversial. In this study, we present clinical outcome and safety of MT in acute ICAD compared to other acute carotid artery pathology.MethodsPatients with symptoms of AIS due to internal carotid artery pathology, treated with MT from 2017-2021, were categorized as ICAD or non-ICAD. Baseline and procedural characteristics, complications, and functional outcome at 90 days were compared between the two groups. Factors associated with a favorable outcome (modified Rankin Scale 0-2) were analyzed using multivariate logistic regression. Safety analyses included in-stent thrombosis, perforation, intracranial hemorrhage, and mortality.ResultsSixty-seven ICAD patients (14.8%) and 387 non-ICAD patients (85.2%) were enrolled. ICAD patients were younger, median age 53 years (interquartile range (IQR) 47-61) vs. non-ICAD 72 years (IQR 64-79), <i>p</i> < 0.001. Favorable outcome was more common in ICAD patients, 49 ICAD patients (76.6%) vs. 158 non-ICAD patients (42.4%), <i>p</i> < 0.001. Post-procedural symptomatic intracranial hemorrhage occurred in 41 patients, 5 (7.5%) ICAD patients vs. 36 (9.3%) non-ICAD patients, <i>p</i> = 0.6. Mortality differed significantly, 6 (9%) ICAD patients vs. 94 (24.3%) non-ICAD patients, <i>p</i> = 0.01. ICAD was not associated with functional outcome in multivariate analysis, OR = 1.25 [95%confidence interval:0.55-2.86].ConclusionICAD patients achieved a better 90-day functional outcome compared with non-ICAD patients. ICAD patients did not perform worse in safety measures than non-ICAD patients. Our data provide indirect evidence that MT is of clinical benefit in ICAD patients with symptoms of AIS.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2081-2087"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141317307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Svetozar Matanov, Georgi Vladev, Alexander Sirakov, Kristian Ninov, Marin Penkov, Hristo Tsonev, Kristina Sirakova, Vasil Karakostov, Stanimir Sirakov
{"title":"The significance of stent sizing for parent vessel stenosis after flow diversion of MCA bifurcation aneurysms.","authors":"Svetozar Matanov, Georgi Vladev, Alexander Sirakov, Kristian Ninov, Marin Penkov, Hristo Tsonev, Kristina Sirakova, Vasil Karakostov, Stanimir Sirakov","doi":"10.1177/15910199241285503","DOIUrl":"10.1177/15910199241285503","url":null,"abstract":"<p><p>BackgroundWide-necked bifurcation aneurysms (WNBA) of the middle cerebral artery (MCA) present significant therapeutic challenges. Flow-diverter stents have been increasingly adopted for their management, though they may give rise to adverse outcomes such as in-stent stenosis (ISS). This study explores the association between stent oversizing and the incidence of ISS following flow-diverter stent placement in MCA bifurcation aneurysms.MethodsA retrospective study included 34 patients who underwent flow-diverter stent placement for MCA bifurcation aneurysms between 2020 and 2023. Data on patient demographics, aneurysm morphology, and stent sizing were collected. ISS was evaluated through follow-up imaging at 6-month post-procedure. Stent oversizing was determined by calculating the difference between the stent diameter and the proximal and distal parent vessel diameters. Statistical analyses included Pearson correlation and chi-square tests, with significance established at <i>p</i> < 0.05.ResultsThe studied group had a mean age of 57.8 years, with 81.6% female patients. The average aneurysm neck size was 3.6 mm, with a mean dome-to-neck ratio of 1.6. ISS was detected in 64.7% of cases proximally and 88.2% distally. A statistically significant negative correlation (<i>r</i> = -0.496, <i>p</i> = 0.003) was observed between stent oversizing and ISS, indicating that increased stent oversizing was associated with a higher incidence of ISS, particularly in the distal vessel segments.ConclusionThe findings indicate that stent oversizing is significantly associated with the development of ISS in MCA bifurcation aneurysms treated with flow-diverter stents. Careful consideration of stent sizing, particularly minimizing oversizing in distal segments, may mitigate the risk of ISS and improve clinical outcomes. These results underscore the importance of meticulous stent selection and procedural planning in neurointerventional practice.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2497-2504"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronil V Chandra, Daniel Cooke, Claus Z Simonsen, Joshua A Hirsch, David Bell
{"title":"Robotic neurointervention: Beyond the noise.","authors":"Ronil V Chandra, Daniel Cooke, Claus Z Simonsen, Joshua A Hirsch, David Bell","doi":"10.1177/15910199241298323","DOIUrl":"10.1177/15910199241298323","url":null,"abstract":"","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2893-2894"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Fernando Pulido, Laura Manuela Olarte Bermúdez, Ana M Rendón-Garavito, Juan Andres Mejia Nuñez
{"title":"Balloon occlusion test: Methodological and reproducibility challenges of a method for the diagnosis of pulsatile tinnitus.","authors":"Luis Fernando Pulido, Laura Manuela Olarte Bermúdez, Ana M Rendón-Garavito, Juan Andres Mejia Nuñez","doi":"10.1177/15910199251339545","DOIUrl":"10.1177/15910199251339545","url":null,"abstract":"","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2891-2892"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Aemaz Ur Rehman, Muhammad Ebaad Ur Rehman, Aqeeb Ur Rehman, Hamza Ali, Mohammad Ammar Ur Rehman, Sherief Ghozy, Muhammad Bilal Tariq, David F Kallmes
{"title":"Efficacy and safety of transradial versus transfemoral access for mechanical thrombectomy in acute ischemic stroke: A systematic review and meta-analysis.","authors":"Muhammad Aemaz Ur Rehman, Muhammad Ebaad Ur Rehman, Aqeeb Ur Rehman, Hamza Ali, Mohammad Ammar Ur Rehman, Sherief Ghozy, Muhammad Bilal Tariq, David F Kallmes","doi":"10.1177/15910199251342049","DOIUrl":"10.1177/15910199251342049","url":null,"abstract":"<p><p>BackgroundMechanical thrombectomy for ischemic stroke has traditionally been performed via transfemoral access (TFA). However, newer literature on the subject suggests that transradial access (TRA) may be equally efficacious.MethodsOnline databases (including PubMed, Google Scholar, Embase, and Cochrane) were queried from inception until May 2024. Abstracts and full texts were screened according to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. Risk of bias assessment was performed using standardized screening tools. All dichotomous outcomes were reported as odds ratio (OR) with 95% confidence interval (CI). RevMan was used to perform the statistical analysis.ResultsThirteen observational studies and one randomized clinical trial (RCT) were included in this meta-analysis. The total sample size was 4973, 4074 patients (81.2%) were in the TFA group, and 899 (18.8%) were in the TRA group. No significant differences were observed between the two groups in terms of successful recanalization (OR = 0.92; 95% CI 0.66-1.27; <i>p</i> = 0.60), first-pass recanalization (OR = 0.84; 95% CI 0.69-1.01, <i>p</i> = 0.06), access to reperfusion time (mean difference -2.99 min; 95% CI -8.33 to 2.44, <i>p</i> = 0.27), and favorable functional outcome. Mortality and rates of intracranial hemorrhage were comparable between the two groups, but access site complications were significantly lower in the TRA group (OR = 0.57; 95% CI 0.37-0.88; <i>p</i> = 0.01).ConclusionTRA for thrombectomy in large vessel ischemic strokes is comparable to TFA in terms of efficacy and has a lower incidence of access site complications. RCT data comparison of the two techniques is limited, underscoring the importance of conducting trials.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2648-2658"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richard Wang, Dhairya A Lakhani, Aneri B Balar, Sadra Sepehri, Nathan Hyson, Licia P Luna, Andrew Cho, Argye E Hillis, Manisha Koneru, Meisam Hoseinyazdi, Hanzhang Lu, Janet Mei, Risheng Xu, Mehreen Nabi, Ishan Mazumdar, Victor C Urrutia, Kevin Chen, Judy Huang, Kambiz Nael, Vivek S Yedavalli
{"title":"The Los Angeles motor scale (LAMS) and ASPECTS score are independently associated with DSA ASITN collateral score.","authors":"Richard Wang, Dhairya A Lakhani, Aneri B Balar, Sadra Sepehri, Nathan Hyson, Licia P Luna, Andrew Cho, Argye E Hillis, Manisha Koneru, Meisam Hoseinyazdi, Hanzhang Lu, Janet Mei, Risheng Xu, Mehreen Nabi, Ishan Mazumdar, Victor C Urrutia, Kevin Chen, Judy Huang, Kambiz Nael, Vivek S Yedavalli","doi":"10.1177/15910199241282434","DOIUrl":"10.1177/15910199241282434","url":null,"abstract":"<p><p>BackgroundMechanical thrombectomy (MT) is the treatment standard in eligible patients with acute ischemic stroke (AIS) secondary to large vessel occlusions (LVO). Studies have shown that good collateral status is a strong predictor of MT efficacy, thus making collateral status important to quickly assess. The Los Angeles Motor Scale is a clinically validated tool for identifying LVO in the field. The aim of this study is to investigate whether admission LAMS score is also associated with the American Society of Interventional and Therapeutic Neuroradiology (ASITN) collateral score on digital subtraction angiography (DSA).MethodsWe conducted a retrospective multicenter cohort study of consecutive patients presenting with AIS caused by LVO from 9/1/2017 to 10/1/2023 with diagnostically adequate DSA imaging. Demographic, clinical, and imaging data was collected through manual chart review. Both univariate and multivariate analysis were applied to assess associations. A <i>p</i>-value <0.05 was considered significant.ResultsA total of 308 patients (median age: 68, IQR: 57.5-77) were included in the study. On multivariate logistic regression analysis, we found that lower admission LAMS score (adjusted OR: 0.82, 95% CI: 0.68-0.98, <i>p</i> < 0.05) and higher ASPECTS score (adjusted OR: 1.21, 95% CI: 1.02-1.42, <i>p</i> < 0.05) were independently associated with good DSA ASITN collateral score of 3-4.ConclusionsAdmission LAMS and ASPECTS score are both independently associated with DSA ASITN collateral score. This demonstrates the capability of LAMS to act as a surrogate marker of CS in the field.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2455-2460"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elliot Pressman, Joshua H Weinberg, Ammad A Baig, Gersham J Rainone, Samantha Schimmel, Joshua Vignolles-Jeong, Teagen Smith, Patrick Youssef, Jason M Davies, Adnan H Siddiqui, Elad I Levy, Waldo R Guerrero, Maxim Mokin, Kunal Vakharia
{"title":"Validity of Woven EndoBridge sizing based on the device-to-aneurysm volume ratio.","authors":"Elliot Pressman, Joshua H Weinberg, Ammad A Baig, Gersham J Rainone, Samantha Schimmel, Joshua Vignolles-Jeong, Teagen Smith, Patrick Youssef, Jason M Davies, Adnan H Siddiqui, Elad I Levy, Waldo R Guerrero, Maxim Mokin, Kunal Vakharia","doi":"10.1177/15910199241298327","DOIUrl":"10.1177/15910199241298327","url":null,"abstract":"<p><p>BackgroundThe Woven EndoBridge (WEB) is a treatment modality available for the treatment of intracranial aneurysms, specifically beneficial in wide-necked bifurcation aneurysms. Conventional sizing methods rely on the manipulation of aneurysm width and height measurements. This results in frequent need for re-sizing after initial WEB insertion attempts. Previous studies have suggested that volume-based sizing may decrease this rate.MethodsWe conducted a multicenter retrospective cohort study in three complex vascular centers in the United States from 1 January 2020 to 30 June 2023. All patients who underwent attempted aneurysmal WEB embolization were included. Using three-dimensional angiogram reconstructions, we measured the aneurysm volume. We calculated the WEB volume and measured the WEB-aneurysm volume (WAVe) ratio. The primary outcome was whether a WEB required re-sizing.ResultsA total of 133 cases were identified, 114 correctly sized and 19 incorrectly sized. Twelve patients (9.0%) required additional stent placement during WEB insertion. One patient (0.8%) had WEB abandonment. There were no differences in demographic or baseline characteristics between the size/re-sizing cohorts aside from aneurysm location (\"other\" and basilar locations increased the rate of re-sizing). The median WAVe ratio in our appropriately sized cohort was 0.997 (interquartile range (IQR) 0.826, 1.30) versus 1.14 in our re-sizing cohort (IQR 0.734, 1.51; <i>p</i> = 0.728). Using logistic regression, we identified a WAVe ratio ranging from 0.76 to 1.24 yielding > 80% probability of a successful sizing with 95% confidence.ConclusionsIncorporating volume-based measurements in aneurysm embolization with WEBs may improve rates of re-sizing but has an unclear effect on aneurysm occlusion. A WAVe ratio of 0.76-1.24 provides the greatest probability of appropriate initial WEB sizing.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2586-2594"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthias Vervoort, Uri Singfer, Lien Van Cauwenberghe, Niels Nordin, Peter Vanlangenhove, Luc Verbeke, Kirsten Colpaert, Edward Baert, Frederic Martens, Luc Defreyne, Elisabeth Dhondt
{"title":"Outcome of early versus late primary embolization in ruptured brain arteriovenous malformations.","authors":"Matthias Vervoort, Uri Singfer, Lien Van Cauwenberghe, Niels Nordin, Peter Vanlangenhove, Luc Verbeke, Kirsten Colpaert, Edward Baert, Frederic Martens, Luc Defreyne, Elisabeth Dhondt","doi":"10.1177/15910199241277583","DOIUrl":"10.1177/15910199241277583","url":null,"abstract":"<p><p>PurposeTo determine whether patients with a ruptured brain arteriovenous malformation (rBAVM) would benefit from an early embolization.MethodsrBAVM treated first by embolization between March 2002 and May 2022 were included. Embolization was defined early (Group 1) when performed within 10 days postbleeding. If later, embolization was considered late (Group 2). Demographic and rBAVM data were compared between the groups. High-risk bleeding components and reasons for deferring embolization were retrieved. Primary endpoint was rebleeding. Secondary endpoints were good functional outcome (FO, modified Rankin Scale mRS ≤ 2) and angiographic occlusion. Predictors of rebleeding and FO were determined by multivariate analysis.Results105 patients were recruited (<i>N</i> = 34 in Group 1; <i>N</i> = 71 in Group 2). No rebleeding was noted before, during or after the first embolization session in the early embolization group. Late embolization depended on missed diagnosis and referral pattern. Eleven patients (10.5%) suffered a rebleeding, of whom <i>N</i> = 3 before embolization (only in Group 2), <i>N</i> = 5 periembolization (<i>N</i> = 2 at the second embolization session in Group 1) and <i>N</i> = 3 spontaneous more than 30 days postembolization. More high-risk components were embolized in Group 1 (19/34; 55.9 vs 17/71; 23.9%; <i>p</i> = .011). Rebleeding rates, FO at last FU (90.9% vs 74.3%) and occlusion rates (80.8% vs 88.5%) did not differ between the groups. Glasgow coma scale ≤ 8 predicted rebleeding, rebleeding correlated with poor FO.ConclusionEarly embolization did prevent rebleeding. The overall rebleeding risk was linked to bleeding before late embolization and bleeding at the second embolization. Rebleeding predicted the final FO.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2298-2313"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}