Interventional Neuroradiology最新文献

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Comparison of safety of lumbar drain versus external ventricular drain in symptomatic hydrocephalus following aneurysmal subarachnoid hemorrhage. 在动脉瘤性蛛网膜下腔出血后出现症状性脑积水时,比较腰椎引流管与脑室外引流管的安全性。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-08-21 DOI: 10.1177/15910199241276676
Kuo Chao, Daniel Martin, Charles Tsouvalas, James Wiginton, Fernando Torres, Nathan Nguyen
{"title":"Comparison of safety of lumbar drain versus external ventricular drain in symptomatic hydrocephalus following aneurysmal subarachnoid hemorrhage.","authors":"Kuo Chao, Daniel Martin, Charles Tsouvalas, James Wiginton, Fernando Torres, Nathan Nguyen","doi":"10.1177/15910199241276676","DOIUrl":"10.1177/15910199241276676","url":null,"abstract":"<p><p>Background and objectiveCerebrospinal fluid (CSF) diversion is typically performed with an external ventricular drain (EVD) for symptomatic hydrocephalus (HCP) following subarachnoid hemorrhage (SAH). Lumbar drain (LD) has also been studied to reduce the incidence of vasospasm after SAH but not HCP. We performed a single center retrospective analysis to evaluate the safety of LD versus EVD for symptomatic HCP following aneurysmal SAH in a naturally randomized patient population.MethodsPatients admitted for aneurysmal SAH who developed symptomatic HCP were treated with EVD or LD depending on neurosurgeon on call. Of the 10 neurosurgeons on call, five would place EVD in all patients while the other five would request LD be placed by interventional neuroradiology; however, the distribution on call was not evenly distributed. We retrospectively compared these two groups for drain complications and outcomes with Modified Rankin Scale (mRS).ResultsFrom 2018 to 2021, there were a total of 77 patients with aneurysmal SAH requiring CSF diversion for HCP. There were 56 cases of EVD placement and 21 cases of LD placement. Overall drain complications were 32.0% of cases with EVD and 9.5% with LD, <i>p</i> = .0773. EVD versus LD complications consisted of hemorrhage (1.8% vs 0%, <i>p</i> = 1.0000), infection (7.1 vs 0%, <i>p</i> = .5698), clogged (25% vs 0%, <i>p</i> = .008), dislodgement (1.8% vs 4.6%, <i>p</i> = .4737) and replacement (16% vs 4.8%, <i>p</i> = .2698). No case of cerebellar tonsillar herniation occurred. mRS between EVD versus LD obtained at baseline (0.3 vs 0.3, <i>p</i> = .3943), discharge (3.8 vs 2.7, <i>p</i> = .047), 90 days (2.9 vs 2.0, <i>p</i> = .060), and 1 year (2.6 vs 1.6, <i>p</i> = .081). One year mortality rates between EVD versus LD (26.8% vs 19.0%, <i>p</i> = .483).ConclusionSymptomatic HCP after aneurysmal SAH can be effectively and safely treated with LD. LD had lower overall complications than EVD with no hemorrhage, infection or malfunction. Further prospective randomized control study may be helpful in elucidating optimal CSF diversion for patients with symptomatic HCP.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2234-2238"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robotic spinal angiography: A single-center experience. 机器人脊柱血管造影术:单中心经验。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-08-08 DOI: 10.1177/15910199241272515
Oleg Shekhtman, Georgios S Sioutas, Mert Marcel Dagli, Irina-Mihaela Matache, Bryan A Pukenas, Brian T Jankowitz, Jan-Karl Burkhardt, Visish M Srinivasan
{"title":"Robotic spinal angiography: A single-center experience.","authors":"Oleg Shekhtman, Georgios S Sioutas, Mert Marcel Dagli, Irina-Mihaela Matache, Bryan A Pukenas, Brian T Jankowitz, Jan-Karl Burkhardt, Visish M Srinivasan","doi":"10.1177/15910199241272515","DOIUrl":"10.1177/15910199241272515","url":null,"abstract":"<p><p>Background and objectivesRobotic neurointervention enhances procedural precision, reduces radiation risk, and improves care access. Originally for interventional cardiology, the CorPath GRX platform has been used in neurointerventions. Recent studies highlight robotic cerebral angiography benefits, but information on spinal angiography is limited. While a new generation of robotic solutions is on the horizon, this series evaluates our experience with the CorPath GRX in spinal angiographic procedures, addressing a key gap in neurointerventional research.MethodsIn this single-center retrospective case series, we analyzed 11 patients who underwent robotic-assisted diagnostic procedures with the CorPath GRX system from February 2022 to March 2023 at our institution. A descriptive synthesis was performed on the demographic, baseline, surgical, and postoperative data collected.ResultsThe average age of the 11 patients was 54 ± 20.34 years, with six (54.55%) female. The mean body mass index was 29.58 ± 7.86, and 7 (63.64%) were non-smokers. Of the 11 procedures using the CorPath GRX system, four (36.36%) were partially converted to manual technique. General anesthesia was used in nine cases (81.82%), and right-side femoral access in ten (90.91%) patients. Mean fluoroscopy time was 24.81 ± 10.19 min, contrast dose 174.09 ± 57.31 mL, dose area product 472.23 ± 437.57 Gy·cm², and air kerma 2438.84 ± 2107.06 mGy. No robot-related complications and minimal procedure-related complications were reported.ConclusionThe CorPath GRX system, a robotic-assisted platform, has proven reliable and safe in spinal angiography, evidenced by its enhanced procedural accuracy and reduced radiation exposure for operators.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2184-2189"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141901754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histotripsy: A novel non-invasive ultrasound technology for precision thrombolysis in acute ischemic stroke management. 组织切片术:一种新的无创超声技术,用于急性缺血性脑卒中管理中的精确溶栓。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2025-06-10 DOI: 10.1177/15910199251347838
Ameer E Hassan, Thomas Dreyer, Yousef Khalili
{"title":"Histotripsy: A novel non-invasive ultrasound technology for precision thrombolysis in acute ischemic stroke management.","authors":"Ameer E Hassan, Thomas Dreyer, Yousef Khalili","doi":"10.1177/15910199251347838","DOIUrl":"10.1177/15910199251347838","url":null,"abstract":"<p><p>BackgroundStroke remains a major cause of morbidity and mortality worldwide. Traditional treatments for ischemic stroke such as mechanical thrombectomy and pharmacological thrombolysis are often less effective or inaccessible for certain patient populations, particularly those with delayed hospital arrival, contraindications to thrombolytics, or in regions with limited access to endovascular care. This study investigates the feasibility of using histotripsy, a non-invasive ultrasound technology, to precisely liquefy thrombi in an artificial experimental setup.MethodsClot analogs were introduced into sample tubes, and focused ultrasound was applied using optimized parameters, including pulses per burst, repetition rates, and output amplitudes. These parameters were systematically adjusted to determine the most effective settings for clot ablation, with a focus on maximizing clot liquefaction while minimizing residual fragments.ResultsHistotripsy achieved complete clot liquefaction within 60-120 s at a repetition rate of 100  Hz, with 1000 pulses per burst and an output amplitude of 100%. The procedure effectively disintegrated soft (red blood cell-rich) clots, leaving minimal residual fragments (<250 microns). However, dense fibrin-rich clots and anatomical barriers like bone presented challenges, suggesting the need for further optimization.ConclusionsThis proof-of-concept study demonstrates the potential of histotripsy as a non-invasive, rapid, and targeted approach for clot removal in stroke management.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2818-2826"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practical uses of the BENCHMARK™ BMX®81 in the road less travelled: Guide catheter comparison for radial access in neurovascular intervention. BENCHMARK™ BMX®81 的实际应用:神经血管介入手术中桡动脉入路引导导管的比较。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-06-14 DOI: 10.1177/15910199241261756
Marco Marangoni, Ian R Macdonald, Gwynedd E Pickett, Adrienne Weeks, Cha-Ney Kim, Axel Rohr, William Guest, Manraj K S Heran, David Volders
{"title":"Practical uses of the BENCHMARK™ BMX®81 in the road less travelled: Guide catheter comparison for radial access in neurovascular intervention.","authors":"Marco Marangoni, Ian R Macdonald, Gwynedd E Pickett, Adrienne Weeks, Cha-Ney Kim, Axel Rohr, William Guest, Manraj K S Heran, David Volders","doi":"10.1177/15910199241261756","DOIUrl":"10.1177/15910199241261756","url":null,"abstract":"<p><p>BackgroundRadial arterial access has gained interest for neurovascular procedures in recent years. Although there are no randomized control trials for neurointervention procedures using radial access, there is growing literature demonstrating its feasibility and favorable outcomes. Equipment technical improvements, like the recently introduced BENCHMARK™ BMX®81 System, have made radial navigation safer, with improved maneuverability and support for a variety of procedures. We present a multicenter case series highlighting our institutional radial access experience comparing the BMX®81 with alternative catheters.MethodsMulticenter retrospective cohort study of 80 patients who underwent neurovascular procedures through a radial approach. In half of the cases a BENCHMARK™ BMX®81 System was used. The comparison group consisted of the BENCHMARK™071 and 96, Neuron MAX®088 and BALLAST™ systems. Procedures included endovascular thrombectomy, carotid and brachiocephalic artery stenting, middle meningeal artery embolization, flow diverter stenting, vertebral artery sacrifice, aneurysm coiling, and WEB™ device deployment.ResultsIn our series, the BMX®81 was successful in the navigation of the anatomy to the target location in 95% of cases. No radial access or BMX®81 related complications were identified. There was no significant difference in fluoroscopy time between the BMX81 and the comparison group. Four patients in the comparison group had catheter-related complications due to vasospasm. Eighty-six percent of BMX®81 cases had satisfactory outcomes and no technical difficulties. The remainder presented technical difficulties, but none of these were considered secondary to the puncture site or support structure.ConclusionsThe BENCHMARK™ BMX®81 System is a recently developed guiding catheter which has design and size features supporting radial access for a variety of neurovascular interventions. Early multicenter experience highlights the ease of use and versatility of this new catheter as an alternative to transfemoral access as well as other catheters used for radial access.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2353-2362"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141317321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a new scale for self-reported procedural patient comfort during endovascular therapy for acute stroke. 为急性脑卒中血管内治疗过程中患者自我报告的程序舒适度开发新量表。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-08-30 DOI: 10.1177/15910199241279228
George Mendes, Alexandre Y Poppe, Olena Bereznyakova, Yan Deschaintre, Laura Gioia, Celine Odier, Christian Stapf, Gregory Jacquin
{"title":"Development of a new scale for self-reported procedural patient comfort during endovascular therapy for acute stroke.","authors":"George Mendes, Alexandre Y Poppe, Olena Bereznyakova, Yan Deschaintre, Laura Gioia, Celine Odier, Christian Stapf, Gregory Jacquin","doi":"10.1177/15910199241279228","DOIUrl":"10.1177/15910199241279228","url":null,"abstract":"<p><p>IntroductionIn stroke patients with acute large vessel occlusion, endovascular therapy (EVT) may be performed with or without sedation. Our aim is to describe self-reported intraprocedural comfort in patients undergoing EVT depending on sedation type.MethodsWe performed a prospective observational single-center study of patients undergoing EVT. Patients were systematically interviewed on the day following intervention using a structured questionnaire addressing five domains (nausea/vomiting, pain of any kind, physical discomfort, emotional discomfort, and medical team interaction). Each domain scored 0 to 2 points for a maximum total of 10 points (a higher score indicating greater discomfort). In addition, satisfaction with procedural comfort was rated on a visual analog scale (VAS), and patients reported whether they would have preferred more, less, or the same amount of sedation. Patients who underwent EVT without sedation (local anesthesia, LA) were compared to those who received procedural sedation (conscious sedation, CS).ResultsSeventy-seven questionnaires were completed: 37 (48%) patients underwent EVT with CS while 40 (52%) were treated under LA. Median scores on the self-reported discomfort scale (1[0-2] vs 1[0-2], p = 0.70) and mean scores on VAS (76 ± 25 vs 81 ± 24, p = 0.37) were similar between the CS and the LA group. The proportion of patients who were satisfied with the adopted sedation strategy was similar between groups.ConclusionEVT without prior sedation seems to be well tolerated. Systematic self-evaluation of patient comfort appears feasible and may become integrated into routine clinical care. Patient-oriented outcomes should be included in future trials of sedation during thrombectomy.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2285-2290"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic value of non-invasive large vessel occlusion detection methods: A systematic review and meta-analysis. 无创大血管闭塞检测方法的诊断价值:系统综述和荟萃分析。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2025-06-02 DOI: 10.1177/15910199251345631
Seyed Behnam Jazayeri, Mohammad Mehdi Mehrabi Nejad, Sherief Ghozy, Noha Hamouda, Baria Ahmad, Ramanathan Kadirvel, David F Kallmes
{"title":"Diagnostic value of non-invasive large vessel occlusion detection methods: A systematic review and meta-analysis.","authors":"Seyed Behnam Jazayeri, Mohammad Mehdi Mehrabi Nejad, Sherief Ghozy, Noha Hamouda, Baria Ahmad, Ramanathan Kadirvel, David F Kallmes","doi":"10.1177/15910199251345631","DOIUrl":"10.1177/15910199251345631","url":null,"abstract":"<p><p>BackgroundAccurate and timely prehospital detection of large vessel occlusion (LVO) is critical for optimizing patient triage and initiating appropriate reperfusion therapies. Recent advances in portable stroke detection technologies, such as electroencephalography (EEG) and transcranial Doppler (TCD) ultrasound, offer potential solutions but their diagnostic performance remains unclear.MethodsWe searched PubMed, Scopus, Embase, and Web of Science, following the PRISMA guidelines. Studies were included if they assessed the diagnostic performance of non-invasive prehospital LVO detection tools compared to CT or MR angiography. Risk of bias was assessed using the QUADAS-2 tool.ResultsA total of 13 studies were included, examining various portable detection tools including EEG or neurophysiological monitoring, ultrasound-based techniques including TCD or TCCD, portable Openwater optical blood flow monitor and cranial accelerometry. The pooled diagnostic odds ratio (DOR) was 52.7 (95% CI: 28.3-97.8), indicating strong diagnostic performance, with significant heterogeneity among studies (I<sup>2</sup> = 67.3%, <i>P</i> < 0.001). Subgroup analysis revealed that TCD-based methods had the highest DOR (120.4, 95% CI: 76.9-188.7), followed by other tools (26.8, 95% CI: 13.7-52.6), and EEG (18.2, 95% CI: 9.1-36.3). The pooled sensitivity was 87.4% (95% CI: 82.5-91.0) and specificity was 89.39% (95% CI: 83.0-93.5) across all methods. TCD-based methods showed the highest specificity (95.0%, 95% CI: 91.8-97.0).ConclusionNon-invasive prehospital LVO detection tools show promising diagnostic performance, particularly TCD-based methods. Future studies should focus on validating these tools in larger, diverse populations to enhance prehospital stroke triage and improve patient outcomes.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2679-2688"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flow diverter versus stent-assisted coiling treatment for managing dissecting intracranial aneurysms: A systematic review and meta-analysis. 分流器与支架辅助盘绕治疗颅内夹层动脉瘤:系统回顾和荟萃分析。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-12-13 DOI: 10.1177/15910199241301820
Leonardo B O Brenner, Milena Zadra Prestes, Cid Soares, Pedro Romeiro, Victor A Gomez, Nicollas Nunes Rabelo, Leonardo C Welling, Stefan W Koester, Agostinho C Pinheiro, Sávio Batista, Raphael Bertani, Eberval Gadelha Figueiredo, Daniel Dutra Cavalcanti
{"title":"Flow diverter versus stent-assisted coiling treatment for managing dissecting intracranial aneurysms: A systematic review and meta-analysis.","authors":"Leonardo B O Brenner, Milena Zadra Prestes, Cid Soares, Pedro Romeiro, Victor A Gomez, Nicollas Nunes Rabelo, Leonardo C Welling, Stefan W Koester, Agostinho C Pinheiro, Sávio Batista, Raphael Bertani, Eberval Gadelha Figueiredo, Daniel Dutra Cavalcanti","doi":"10.1177/15910199241301820","DOIUrl":"10.1177/15910199241301820","url":null,"abstract":"<p><p>BackgroundDissecting intracranial aneurysms (DIAs) have been treated through endovascular reconstructive manners, such as flow diverters (FDs) and stent-assisted coiling (SAC). Notably, no robust evidence has compared both approaches. Hence, the authors conducted a meta-analysis to compare their outcomes.MethodsPubMed, Embase and Web of Science were searched for studies employing SAC and FD treatment for DIAs. The following outcomes were considered for extraction: procedure-related mortality, total mortality, postoperative and follow-up complete aneurysm occlusion, complications, good clinical outcomes, recurrence, and retreatment. Odds ratio (OR) with random effects was employed for statistical comparison.ResultsThe meta-analysis included 10 studies. A total of 195 and 222 patients were included in the FD and the SAC group, respectively. Stent-assisted coiling had higher postoperative complete aneurysm occlusion rates (OR 0.03; 95% CI 0.01-0.08). Flow diverter retreatment rate was lower, but without statistical significance (OR 0.35; 95% CI 0.11-1.10). No significant differences were found in follow-up complete aneurysm occlusion (OR 1.18; 95% CI 0.35-3.99); total mortality (OR 0.44; 95% CI 0.09-2.08); intraoperative complications (OR 0.30; 95% CI 0.06-1.45); postoperative complication (OR 0.77; 95% CI 0.35-1.70); good clinical outcomes (OR 0.97; 95% CI 0.43-2.20); and recurrence (OR 0.38; 95% CI 0.13-1.10) between the two groups.ConclusionStent-assisted coiling shows higher postoperative complete aneurysmal occlusion rates, but both techniques achieve similar rates in angiographic follow-up. Flow diverter has lower, but not statistically significant, retreatment rates than SAC. Both techniques have similar complication rates. Future randomized, multicenter, and prospective studies with larger sample sizes are needed for more conclusive findings.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2719-2729"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revisiting intra-arterial chemotherapy-palliative utility in a case of recurrent esthesioneuroblastoma and literature review. 动脉内化疗-姑息治疗复发性神经母细胞瘤1例及文献复习。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2025-07-24 DOI: 10.1177/15910199251362087
Bernard Okai, Jaims Lim, Vinay Jaikumar, Moleca Ghannam, Laszlo L Mechtler, Kunal Vakharia, Adnan H Siddiqui, Elad I Levy
{"title":"Revisiting intra-arterial chemotherapy-palliative utility in a case of recurrent esthesioneuroblastoma and literature review.","authors":"Bernard Okai, Jaims Lim, Vinay Jaikumar, Moleca Ghannam, Laszlo L Mechtler, Kunal Vakharia, Adnan H Siddiqui, Elad I Levy","doi":"10.1177/15910199251362087","DOIUrl":"10.1177/15910199251362087","url":null,"abstract":"<p><p>BackgroundEsthesioneuroblastomas (ENBs) are rare, aggressive tumors arising from the olfactory neuroepithelium in the superior nasal tract. Current treatment strategies typically involve a combination of surgery and radiation, with systemic chemotherapy considered on a case-by-case basis. However, the role of intra-arterial (IA) therapies for ENBs remains underexplored. In this report, we present an illustrative case from our center and a systematic literature review compiling an overview of similar cases.MethodsThe case of an elderly man with recurrent ENB treated with IA carboplatin is described. We systematically reviewed PubMed and Embase to gather data on the indications, treatment course, and outcomes of IA chemotherapy for ENBs.ResultsThe patient presented initially with epistaxis and was diagnosed with ENB post-resection and radiation. Recurrence occurred 28 years later, causing visual loss and headaches. Multiple sessions of stereotactic radiosurgery over 2 years were ineffective. After multispecialty discussions, IA carboplatin was selected for neoadjuvant therapy. The bilateral internal maxillary arteries (IMAs) were identified as primary feeders of the recurrence. Carboplatin was directly administered via the IMAs in two stages, 1 month apart. The procedures were well-tolerated, and the patient was discharged without complications. Despite symptom improvement with radiographically stable tumor at 2-month follow-up, the patient opted for palliative care. The systematic review identified four ENB cases involving the ethmoid sinus with varying extensions into anterior and middle cranial fossae. IA chemotherapeutics were administered through maxillary or carotid arteries as an adjunct to resection, radiotherapy, or systemic chemotherapy, with no intraprocedural or postprocedural complications reported. Two patients died during follow-up: one with primary ENB and another with recurrent ENB.ConclusionThe safe administration of IA chemotherapeutics for primary and recurrent ENB in this case and literature review suggests a potential role for IA therapies in managing intracranial tumors, especially with advanced superselective microcatheter techniques.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2916-2923"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjunctive venous sinus stenting in transvenous embolization of vein of Galen malformations. 经静脉栓塞治疗盖伦静脉畸形时辅助静脉窦支架植入术。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-10-03 DOI: 10.1177/15910199241282719
Alex Devarajan, Daryl Goldman, Jessica Bonet, Brandon D Philbrick, Cornelius Deuschl, Elif Yamac, Ahmed Ayad, Halima Tabani, Michelle Sorscher, Alejandro Berenstein, Johanna T Fifi, René Chapot, Tomoyoshi Shigematsu
{"title":"Adjunctive venous sinus stenting in transvenous embolization of vein of Galen malformations.","authors":"Alex Devarajan, Daryl Goldman, Jessica Bonet, Brandon D Philbrick, Cornelius Deuschl, Elif Yamac, Ahmed Ayad, Halima Tabani, Michelle Sorscher, Alejandro Berenstein, Johanna T Fifi, René Chapot, Tomoyoshi Shigematsu","doi":"10.1177/15910199241282719","DOIUrl":"10.1177/15910199241282719","url":null,"abstract":"<p><p>BackgroundVein of Galen malformations are congenital arteriovenous malformations primarily treated by endovascular embolization via transarterial or transvenous approaches. transvenous embolization can be utilized to close the malformation but may be difficult in patients with venous stenosis or blockages, which drive venous hypertension and lead to significant neurologic consequences. Here, we illustrate the atypical placement of an intracranial venous sinus stent to improve outflow after transvenous embolization in pediatric patients with the vein of Galen malformation.MethodsA retrospective review of clinical databases at two high-volume endovascular centers from January 2018 to March 2023 identified all vein of Galen malformation patients who received a venous sinus stent during transvenous embolization. Clinical data, imaging, angioarchitecture, operative details, postoperative management, and follow-up were reviewed.ResultsThree patients presented for transvenous embolization after multiple staged transarterial embolizations of their vein of Galen malformation. Transvenous access was complicated by lateral sinus stenosis, which was temporarily relieved by balloon angioplasty. After transvenous embolization by pressure cooker technique, the dural sinuses were stented using the existing venous guide catheter. Venous angiography demonstrated improved flow across the stenosed areas and post-embolization angiography demonstrated normalized venous drainage with widely patent stents. One patient experienced postoperative oculomotor nerve palsy unrelated to the stent placement. All patients demonstrated a complete cure of their vein of Galen malformations with patent venous sinus stents on follow-up.ConclusionIn patients with the vein of Galen malformation and venous hypertension receiving transvenous embolization, venous sinus stenting may be a safe and effective option to reduce aberrant cortical venous drainage and improve normal outflow. Further studies are warranted to investigate its benefit in high-flow vascular malformations.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2431-2439"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing visualization performance of liquid embolic agents using a novel injectable phantom. 使用新型注射模型比较液体栓塞剂的可视化性能。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-08-21 DOI: 10.1177/15910199241276581
J Ryan Mason, Cristina Dodge, Adam Beardsley, Susan Hilsenbeck, Goetz Benndorf
{"title":"Comparing visualization performance of liquid embolic agents using a novel injectable phantom.","authors":"J Ryan Mason, Cristina Dodge, Adam Beardsley, Susan Hilsenbeck, Goetz Benndorf","doi":"10.1177/15910199241276581","DOIUrl":"10.1177/15910199241276581","url":null,"abstract":"<p><p>BackgroundRadiographic visualization of liquid embolic agents (LEAs) during embolization procedures in neurovascular territory represents a crucial feature to ensure efficacy and safety for the patients during endovascular treatment of arteriovenous shunting lesions. Radiopacity of available LEAs varies significantly and limited methods are currently available for comparison. The purpose of this study was to compare the contrast resolution (CR) during injection under blank roadmap of various LEAs, as well as standard contrast material.MethodsAn injectable angiographic phantom was designed consisting of parallel tubings between 313 and 1000 micron. Under roadmap, eight radiopaque liquid agents were injected and analyzed: Onyx18<sup>®</sup>, 34<sup>®</sup> Squid<sup>®</sup>12, 18, PHIL<sup>®</sup>25% (PHIL<sup>®</sup>25), PHIL<sup>®</sup>30% (PHIL<sup>®</sup>30).Trufill<sup>TM</sup> (NBCA), 30% dilution and Omnipaque<sup>®</sup>300. CR was evaluated as a contrast to noise ratio (CNR) and calculated as mean peak signal (Sa) minus mean background signal (Sb) divided by the standard deviation of the background signal (Std) <math><mrow><mo>(</mo><mi>C</mi><mi>N</mi><mi>R</mi><mo>=</mo><mspace></mspace><mfrac><mrow><mi>S</mi><mi>a</mi><mo>-</mo><mi>S</mi><mi>b</mi></mrow><mrow><mi>S</mi><mi>t</mi><mi>d</mi><mspace></mspace></mrow></mfrac><mo>)</mo></mrow></math>.ResultsOmnipaque 300 and NBCA were found to have the highest CR. PHIL<sup>®</sup>25 demonstrated the lowest CNR (45% of Omnipaque CNR). Onyx 18 and 34 (Both around 82% of Omnipaque CNR) demonstrated higher CNR compared to Squid<sup>®</sup>12 and 18 (52-55% of Omnipaque CNR). On average, at 500 micron there is a >70% reduction in CNR, and at 313 micron there is a 90% reduction in CNR compared to 1000 micron.ConclusionsSignificantly different CNR between most LEAs and iodinated contrast media was evident under roadmap conditions and should be considered prior to injection.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2447-2454"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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