Interventional Neuroradiology最新文献

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Transradial versus transfemoral access for mechanical thrombectomy: A single institution experience. 经桡动脉与经股动脉入路进行机械血栓切除术:单个医疗机构的经验。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-11-15 DOI: 10.1177/15910199241298725
Richard Bram, James W Nie, Peter Theiss, Dario Marotta, Maureen Hillman, Ali Alaraj, Gursant S Atwal
{"title":"Transradial versus transfemoral access for mechanical thrombectomy: A single institution experience.","authors":"Richard Bram, James W Nie, Peter Theiss, Dario Marotta, Maureen Hillman, Ali Alaraj, Gursant S Atwal","doi":"10.1177/15910199241298725","DOIUrl":"10.1177/15910199241298725","url":null,"abstract":"<p><strong>Background: </strong>There has been debate in the literature regarding the adoption of a \"radial-first\" approach for mechanical thrombectomy (MT) in acute ischemic stroke (AIS). Conflicting reports suggest that transradial access (TRA) may allow for shorter times to reperfusion while others conclude that long-term functional outcomes may favor transfemoral access (TFA). Here, we report a single-institution experience with the adoption of TRA as the primary route for acute stroke intervention.</p><p><strong>Methods: </strong>We retrospectively reviewed a single-institution database of patients undergoing MT for AIS from March 2020 to April 2023. This time period was selected to capture the change in clinical practice at our institution from TFA to TRA. Primary and secondary outcomes included technical success, procedural complications, and long-term functional outcomes. Patients were stratified into two cohorts from initial access. Cohorts were compared utilizing inferential statistics.</p><p><strong>Results: </strong>A total of 192 consecutive cases were identified, with 80 in the TFA cohort and 112 in the TRA cohort. There was no difference in outcomes with respect to time from puncture to recanalization, rates of successful recanalization (TICI ≥ 2b), number of passes, rates of symptomatic intracranial hemorrhage (sICH), modified Rankin scale (mRS) at discharge and 90 days, and 90-day mortality (<i>p</i> ≥ 0.05, all). The TRA had a higher rate of access conversion (<i>p</i> < 0.001), while the TFA cohort had a higher rate of access site complications (<i>p</i> < 0.05).</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11565504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balloon angioplasty for cerebral vasospasm in preschool children. 球囊血管成形术治疗学龄前儿童脑血管痉挛。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-11-15 DOI: 10.1177/15910199241293173
Zeferino Demartini, Flavio Requejo, Renato Fedato Beraldo, Adriano Keijiro Maeda, Alexandre Mello Savoldi, Adriane Cardoso-Demartini
{"title":"Balloon angioplasty for cerebral vasospasm in preschool children.","authors":"Zeferino Demartini, Flavio Requejo, Renato Fedato Beraldo, Adriano Keijiro Maeda, Alexandre Mello Savoldi, Adriane Cardoso-Demartini","doi":"10.1177/15910199241293173","DOIUrl":"10.1177/15910199241293173","url":null,"abstract":"<p><strong>Background: </strong>Subarachnoid hemorrhage evolving with cerebral vasospasm and delayed cerebral ischemia may increase morbidity and mortality. Treating vasospasm with balloon percutaneous angioplasty (PTA) in adults is well known, but data in preschool children are scarce. In addition, the smaller diameters and fragility of the vessels in childhood might lead to serious complications. This study presents two cases of cerebral vasospasm in preschool children treated with balloon PTA. Therefore, it may contribute to a better understanding of the role of that technique as an effective treatment modality in this population.</p><p><strong>Methods: </strong>Balloon PTA was performed in two children (3 and 4 year-old) with aneurysmal subarachnoid hemorrhage and delayed cerebral ischemia.</p><p><strong>Results: </strong>The procedures were uneventful, and both patients survived without complications or new infarction.</p><p><strong>Conclusions: </strong>Balloon PTA for proximal vasospasm may improve clinical outcomes in selected pediatric patients. Further studies are needed to clarify the best candidates, materials, and techniques.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11565503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity of Woven EndoBridge sizing based on the device-to-aneurysm volume ratio. 根据设备与动脉瘤体积比确定 Woven EndoBridge 尺寸的有效性。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-11-14 DOI: 10.1177/15910199241298327
Elliot Pressman, Joshua H Weinberg, Ammad A Baig, Gersham J Rainone, Samantha Schimmel Ba, Joshua Vignolles-Jeong, Teagen Smith, Patrick Youssef, Jason M Davies, Adnan H Siddiqui, Elad I Levy, Waldo R Guerrero, Maxim Mokin, Kunal Vakharia
{"title":"Validity of Woven EndoBridge sizing based on the device-to-aneurysm volume ratio.","authors":"Elliot Pressman, Joshua H Weinberg, Ammad A Baig, Gersham J Rainone, Samantha Schimmel Ba, Joshua Vignolles-Jeong, Teagen Smith, Patrick Youssef, Jason M Davies, Adnan H Siddiqui, Elad I Levy, Waldo R Guerrero, Maxim Mokin, Kunal Vakharia","doi":"10.1177/15910199241298327","DOIUrl":"10.1177/15910199241298327","url":null,"abstract":"<p><strong>Background: </strong>The Woven EndoBridge (WEB) is a treatment modality available for the treatment of intracranial aneurysms, specifically beneficial in wide-necked bifurcation aneurysms. Conventional sizing methods rely on the manipulation of aneurysm width and height measurements. This results in frequent need for re-sizing after initial WEB insertion attempts. Previous studies have suggested that volume-based sizing may decrease this rate.</p><p><strong>Methods: </strong>We conducted a multicenter retrospective cohort study in three complex vascular centers in the United States from 1 January 2020 to 30 June 2023. All patients who underwent attempted aneurysmal WEB embolization were included. Using three-dimensional angiogram reconstructions, we measured the aneurysm volume. We calculated the WEB volume and measured the WEB-aneurysm volume (WAVe) ratio. The primary outcome was whether a WEB required re-sizing.</p><p><strong>Results: </strong>A total of 133 cases were identified, 114 correctly sized and 19 incorrectly sized. Twelve patients (9.0%) required additional stent placement during WEB insertion. One patient (0.8%) had WEB abandonment. There were no differences in demographic or baseline characteristics between the size/re-sizing cohorts aside from aneurysm location (\"other\" and basilar locations increased the rate of re-sizing). The median WAVe ratio in our appropriately sized cohort was 0.997 (interquartile range (IQR) 0.826, 1.30) versus 1.14 in our re-sizing cohort (IQR 0.734, 1.51; <i>p</i> = 0.728). Using logistic regression, we identified a WAVe ratio ranging from 0.76 to 1.24 yielding > 80% probability of a successful sizing with 95% confidence.</p><p><strong>Conclusions: </strong>Incorporating volume-based measurements in aneurysm embolization with WEBs may improve rates of re-sizing but has an unclear effect on aneurysm occlusion. A WAVe ratio of 0.76-1.24 provides the greatest probability of appropriate initial WEB sizing.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accelerated aspiration with Q™ catheter: An in vitro study. 使用 Q™ 导管加速抽吸:体外研究
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-11-06 DOI: 10.1177/15910199241273974
Philippe Reymond, Mayra Contreras, Olivier Brina, Trent Langston, Naomi Chesler, Waleed Brinjikji, John Wainwright, Paolo Machi
{"title":"Accelerated aspiration with Q™ catheter: An <i>in vitro</i> study.","authors":"Philippe Reymond, Mayra Contreras, Olivier Brina, Trent Langston, Naomi Chesler, Waleed Brinjikji, John Wainwright, Paolo Machi","doi":"10.1177/15910199241273974","DOIUrl":"https://doi.org/10.1177/15910199241273974","url":null,"abstract":"<p><strong>Background and purpose: </strong>Thrombectomy in distal, medium vessels is a topic of increasing interest. To date, there are few <i>in vitro</i> studies focused on performance of ≤5F catheters in medium vessels. The purpose of this study is to compare the performance of the 3F, 4F, and 5F MIVI Neuroscience Q Catheters versus Penumbra 3F, 4F, and MicroVention Sofia 5F Catheters.</p><p><strong>Methods: </strong>Using <i>in vitro</i> methods, we assessed and compared the following parameters: aspiration flow rates, clot uncorking forces, impulse, and clot ingestion. For flow rate, each aspiration catheter was immersed in a cylindrical container. Flow rate at one second was used to calculate impulse. For clot uncorking force, the force required to disengage a catheter from a simulated clot was recorded. For ingestion, we measured time to ingest soft and medium stiffness synthetic clots.</p><p><strong>Results: </strong>The measured flow rates without a stent retriever for the Q3, Q4, and Q5 catheters were 3.54 ml/s, 5.32 ml/s, and 6.87 ml/s. The measured flow rates without a stent retriever for the 3MAX, 4MAX, and 5F Sofia were 1.46 ml/s, 2.56 ml/s, and 1.73 ml/s. The impulse calculated for one second was 26 mNs for Q5 vs 9 mNs for Sofia 5, 35 mNs for Q4 vs 15 mNs for 4Max< and 35 mNs for Q3 vs 9 mNs for 3Max. The average system ingestion for Q was significantly faster than the competitive catheters.</p><p><strong>Conclusions: </strong>The Q catheters demonstrated higher flow rates, higher uncorking force, and faster complete clot ingestion than competitive catheters.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High mechanical thrombectomy procedural volume is not a reliable predictor of improved thrombectomy outcomes in patients with acute ischemic stroke in the United States. 在美国,机械血栓切除术的手术量大并不能可靠地预测急性缺血性中风患者的血栓切除效果。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-11-06 DOI: 10.1177/15910199241288611
Adnan I Qureshi, Hamza Maqsood, Daniel E Ford, Camilo R Gomez, Daniel F Hanley, Ameer E Hassan, Thanh N Nguyen, Farhan Siddiq, Alejandro M Spiotta, Syed F Zaidi, Chun Shing Kwok
{"title":"High mechanical thrombectomy procedural volume is not a reliable predictor of improved thrombectomy outcomes in patients with acute ischemic stroke in the United States.","authors":"Adnan I Qureshi, Hamza Maqsood, Daniel E Ford, Camilo R Gomez, Daniel F Hanley, Ameer E Hassan, Thanh N Nguyen, Farhan Siddiq, Alejandro M Spiotta, Syed F Zaidi, Chun Shing Kwok","doi":"10.1177/15910199241288611","DOIUrl":"10.1177/15910199241288611","url":null,"abstract":"<p><strong>Background: </strong>The volume of mechanical thrombectomy (MT) performed at hospitals is used as one of the criteria for advanced-level designation for stroke care.</p><p><strong>Objective: </strong>Our study sought to determine the relationship between annual MT procedural volume and in-hospital outcomes in acute ischemic stroke patients undergoing MT in the United States.</p><p><strong>Methods: </strong>We analyzed the National Inpatient Sample from 2016 to 2020. The hospitals were grouped into quartiles based on the volume of MT procedures performed within the calendar year. We compared the rates of routine discharge/home health care; in-hospital mortality, and post-treatment intracranial hemorrhage (ICH) between the quartiles after adjusting for potential confounders.</p><p><strong>Results: </strong>Patients undergoing MT ranged from 15,395 in quartile 1 to 78,510 MT in quartile 4. There were lower rates of discharge home/self-care of 22.5%, 20.8%, and 20.8% for quartiles 2, 3, and 4, respectively, compared with 34.9% in quartile 1. The odds of ICH increased to 1.81 (<i>p</i> < 0.001), 1.84 (<i>p</i> < 0.001), and 1.98 (<i>p</i> < 0.001) among the quartiles from lowest to highest procedural volumes. The odds of home discharge/self-care decreased to 0.66 (<i>p</i> < 0.001), 0.60 (<i>p</i> < 0.001), and 0.63 (<i>p</i> < 0.001) among the quartiles from lowest to highest procedural volumes. The odds of in-hospital mortality increased to 1.92 (<i>p</i> < 0.001), 1.99 (<i>p</i> < 0.001), and 1.84 (<i>p</i> < 0.001) among the quartiles from lowest to highest procedural volumes.</p><p><strong>Conclusions: </strong>We observed a paradoxical relationship between adverse outcomes and the annual procedural volume of MT at the hospital presumably due to the higher severity of acute ischemic stroke treated at high-volume hospitals.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Onyx Frontier for intracranial stenting in stroke patients: A multicenter retrospective study. 在脑卒中患者中使用 Onyx Frontier™ 进行颅内支架植入术:一项多中心回顾性研究。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-21 DOI: 10.1177/15910199241286922
Ahmad Chahine, Rami Z Morsi, Sonam Thind, Omar Kass-Hout, Tibor Becske, Ahmad Khaldi, Lina Karar, Archit Baskaran, Julián Carrión-Penagos, Harsh Desai, Sachin A Kothari, Rohini Rana, Okker Verhagen Metman, Jehad Zakaria, Atman P Shah, Jonathan D Paul, Sandeep Nathan, James E Siegler, Scott J Mendelson, Ali Mansour, Michael C Hurley, Shyam Prabhakaran, Rishi Gupta, Tareq Kass-Hout
{"title":"Use of Onyx Frontier<sup>™</sup> for intracranial stenting in stroke patients: A multicenter retrospective study.","authors":"Ahmad Chahine, Rami Z Morsi, Sonam Thind, Omar Kass-Hout, Tibor Becske, Ahmad Khaldi, Lina Karar, Archit Baskaran, Julián Carrión-Penagos, Harsh Desai, Sachin A Kothari, Rohini Rana, Okker Verhagen Metman, Jehad Zakaria, Atman P Shah, Jonathan D Paul, Sandeep Nathan, James E Siegler, Scott J Mendelson, Ali Mansour, Michael C Hurley, Shyam Prabhakaran, Rishi Gupta, Tareq Kass-Hout","doi":"10.1177/15910199241286922","DOIUrl":"10.1177/15910199241286922","url":null,"abstract":"<p><strong>Background: </strong>Acute ischemic stroke (AIS) due to intracranial atherosclerotic disease (ICAD) carries a high risk of recurrence despite aggressive medical management. The aim of our study is to present our initial experience with the Onyx Frontier™ balloon-mounted drug-eluting stent (Medtronic, Santa Rosa, CA) for AIS due to ICAD.</p><p><strong>Methods: </strong>We conducted a multicenter retrospective cohort study describing the technical feasibility, safety, and performance of using the Onyx Frontier™ balloon-mounted drug-eluting stent in patients with acute intracranial vessel occlusion due to ICAD across three comprehensive stroke centers in the United States.</p><p><strong>Results: </strong>We included 23 patients in our study (mean age 67.3 [10.7]; females: n = 13/23, 56.5%). Most patients were Black (n = 14/23, 60.9%). The most common site of vessel occlusion was the M1 branch of the middle cerebral artery (MCA) (n = 14/23, 60.9%), followed by the vertebrobasilar system (n = 5/23, 21.7%), and the internal carotid artery (n = 3/23, 13.0%). Treatment with the Onyx Frontier™ stent was associated with a final mTICI score ≥2b for 100% of patients, with no vessel perforations or distal embolization. None of the patients had any restenosis or re-treatment over a median follow-up of 3.5 months (interquartile range [IQR] 7.8). All cases required a single stent except for one, where two were deployed. Transfemoral access was used in most cases (n = 18/23, 78.3%), with one in-hospital death due to access site complication (n = 1/23, 4.3%).</p><p><strong>Conclusions: </strong>This is the largest multicenter cohort study demonstrating the feasibility and safety of using the Onyx Frontier™ balloon-mounted zotarolimus-eluting stent to treat symptomatic AIS due to ICAD.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carotid artery stenting for symptomatic carotid near occlusions: Feasibility, safety and outcome analysis. 颈动脉支架治疗无症状颈动脉近端闭塞:可行性、安全性和结果分析。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-21 DOI: 10.1177/15910199241292387
Emre Can Çelebioğlu, Guilherme Dabus, Sena Bozer Uludağ, Ömer Arda Çetinkaya, Sena Ünal, Uğur Bengisun, Sadık Eryılmaz, Mine Hayriye Sorgun, İhsan Doğan, Şermin Atmaca, Evren Özçınar, Başak Ceyda Meço, Mustafa Bahadır İnan, Canan Togay Işıkay, Ahmet Rüçhan Akar, İskender Alaçayır, Sadık Bilgiç
{"title":"Carotid artery stenting for symptomatic carotid near occlusions: Feasibility, safety and outcome analysis.","authors":"Emre Can Çelebioğlu, Guilherme Dabus, Sena Bozer Uludağ, Ömer Arda Çetinkaya, Sena Ünal, Uğur Bengisun, Sadık Eryılmaz, Mine Hayriye Sorgun, İhsan Doğan, Şermin Atmaca, Evren Özçınar, Başak Ceyda Meço, Mustafa Bahadır İnan, Canan Togay Işıkay, Ahmet Rüçhan Akar, İskender Alaçayır, Sadık Bilgiç","doi":"10.1177/15910199241292387","DOIUrl":"10.1177/15910199241292387","url":null,"abstract":"<p><strong>Introduction: </strong>Extracranial internal carotid stenosis (EICS) is a well-established cause of stroke. Carotid near-occlusion (CNO), either distally collapsed or not, is a rare sub-type of EICS with conflicting data regarding the necessity for treatment. The aim of this study is to evaluate the results of carotid artery stenting (CAS) for patients with symptomatic CNOs.</p><p><strong>Material and methods: </strong>Institutional review board (I06-420-23) approval was obtained for this retrospective study. Consecutive data from January 2019 to January 2023 was obtained. Sixty-five patients underwent 66 procedures for symptomatic CNOs. Diagnosis of CNOs were made with DSA images. Treatment decisions were made by a multidisciplinary team. Patient data including age, gender, clinical presentation, affected side, complications (initial/ follow-up), and pre and post mRS scores were recorded and analyzed.</p><p><strong>Results: </strong>There were 22 female and 43 male patients with symptomatic CNOs (mean age: 71.52 ± 9.32 years). The mean time from symptom-to-treatment was 3.91 weeks ± 3.74 weeks (ranging from 0 to 20 weeks). There were eight events recorded in the 30 days period after CAS; five (7.7%) were cerebral hyperperfusion syndrome (one causing haemorrhage) and three (4.5%) ischemic complications. Permanent neurologic deficit rate was 6% and 61 patients (94%) mRS scores were unchanged during last follow-up. Mean follow-up period was 22.94 ± 16.67 months (ranging from 0.5 to 60 months).</p><p><strong>Conclusion: </strong>Our study demonstrated that in the complex population of patients with symptomatic CNOs, CAS is a feasible option with acceptable rate of permanent neurologic deficits. Further studies are needed to assess its safety and long-term efficacy.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of D-dimer on the outcomes of endovascular thrombectomy for acute ischemic stroke: A systematic review and meta-analysis. D 二聚体对急性缺血性脑卒中血管内血栓切除术疗效的影响:系统回顾和荟萃分析。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-14 DOI: 10.1177/15910199241289628
Abdullah Reda, Sherief Ghozy, Mohamed Elfil, Eris Spirollari, Aryan Gajjar, Fawaz Al-Mufti
{"title":"Impact of D-dimer on the outcomes of endovascular thrombectomy for acute ischemic stroke: A systematic review and meta-analysis.","authors":"Abdullah Reda, Sherief Ghozy, Mohamed Elfil, Eris Spirollari, Aryan Gajjar, Fawaz Al-Mufti","doi":"10.1177/15910199241289628","DOIUrl":"10.1177/15910199241289628","url":null,"abstract":"<p><strong>Background: </strong>There has been growing data about the association between D-dimer levels and thrombectomy outcomes in acute ischemic stroke patients (AIS) with no cumulative evidence. This systematic review and meta-analysis aim to discuss and analyze the findings of the current studies to provide more robust evidence in this regard.</p><p><strong>Methods: </strong>A systematic search was conducted through PubMed, Web of Science, Embase, and Scopus to retrieve all relevant investigations. A meta-analysis was conducted, and the results were presented in odds ratio (ORs) for binary variables and ratio of means (ROM) for continuous variables, each accompanied by its respective 95% confidence intervals (CIs).</p><p><strong>Results: </strong>After searching and screening, 14 studies were included. The analysis showed that the low D-dimer group had significantly higher rates of favorable functional outcome (OR: 4.40; 95%CI: 2.65-7.30; <i>p</i> < 0.001, n = 3) and recanalization (OR: 4.13; 95%CI: 1.57-10.84; <i>p</i> = 0.004, n = 3) than the high one. The association between D-dimer levels and first-pass effect and re-occlusion risk was also demonstrated. Eventually, two studies also demonstrated a significant association between high D-dimer levels and deep venous thrombosis and symptomatic intracranial hemorrhage as post-thrombectomy complications.</p><p><strong>Conclusion: </strong>Current evidence indicates a significant association between D-dimer levels and post-thrombectomy outcomes in AIS patients. However, current data are remarkably heterogeneous, and additional comparative investigations are needed.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of reperfusion grade and reperfusion strategy on the clinical outcome: Insights from ESCAPE-NA1 trial. 再灌注等级和再灌注策略对临床结果的影响:ESCAPE-NA1试验的启示。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-14 DOI: 10.1177/15910199241288874
Petra Cimflova, Johanna M Ospel, Nishita Singh, Martha Marko, Nima Kashani, Arnuv Mayank, Andrew Demchuk, Bijoy Menon, Alexandre Y Poppe, Raul Nogueira, Ryan McTaggart, Jeremy L Rempel, Michael Tymianski, Michael D Hill, Mohammed A Almekhlafi, Mayank Goyal
{"title":"Effects of reperfusion grade and reperfusion strategy on the clinical outcome: Insights from ESCAPE-NA1 trial.","authors":"Petra Cimflova, Johanna M Ospel, Nishita Singh, Martha Marko, Nima Kashani, Arnuv Mayank, Andrew Demchuk, Bijoy Menon, Alexandre Y Poppe, Raul Nogueira, Ryan McTaggart, Jeremy L Rempel, Michael Tymianski, Michael D Hill, Mohammed A Almekhlafi, Mayank Goyal","doi":"10.1177/15910199241288874","DOIUrl":"10.1177/15910199241288874","url":null,"abstract":"<p><strong>Background: </strong>We evaluated the association of reperfusion quality and different patterns of achieved reperfusion with clinical and radiological outcomes in the ESCAPE NA1 trial.</p><p><strong>Methods: </strong>Data are from the ESCAPE-NA1 trial. Good clinical outcome [90-day modified Rankin Scale (mRS) 0-2], excellent outcome (90-day mRS0-1), isolated subarachnoid hemorrhage, symptomatic hemorrhage (sICH) on follow-up imaging, and death were compared across different levels of reperfusion defined by expanded Treatment in Cerebral Infarction (eTICI) Scale. Comparisons were also made between patients with (a) first-pass eTICI 2c3 reperfusion vs multiple-pass eTICI 2c3; (b) final eTICI 2b reperfusion vs eTICI 2b converted-to-eTICI 2c3; (c) sudden reperfusion vs gradual reperfusion if >1 pass was required. Multivariable logistic regression was used to test associations of reperfusion grade and clinical outcomes.</p><p><strong>Results: </strong>Of 1037 included patients, final eTICI 0-1 was achieved in 46 (4.4%), eTICI 2a in 76 (7.3%), eTICI 2b in 424 (40.9%), eTICI 2c in 284 (27.4%), and eTICI 3 in 207 (20%) patients. The odds for good and excellent clinical outcome gradually increased with improved reperfusion grades (adjOR ranging from 5.7-29.3 and 4.3-17.6) and decreased for sICH and death. No differences in outcomes between first-pass versus multiple-pass eTICI 2c3, eTICI 2b converted-to-eTICI 2c3 versus unchanged eTICI 2b and between sudden versus gradual eTICI 2c3 reperfusion were observed.</p><p><strong>Conclusion: </strong>Better reperfusion degrees significantly improved clinical outcomes and reduced mortality, independent of the number of passes and whether eTICI 2c3 was achieved suddenly or gradually.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of balloon guide catheters during venous sinus stenting: A case series. 静脉窦支架术中球囊导引导管的使用:病例系列。
IF 1.7 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-14 DOI: 10.1177/15910199241289458
Justin Turpin, Timothy G White, Daniel Toscano, Siddharth Dalal, Miriam M Shao, Shyle H Mehta, Jared B Bassett, Kevin A Shah, Athos Patsalides
{"title":"The use of balloon guide catheters during venous sinus stenting: A case series.","authors":"Justin Turpin, Timothy G White, Daniel Toscano, Siddharth Dalal, Miriam M Shao, Shyle H Mehta, Jared B Bassett, Kevin A Shah, Athos Patsalides","doi":"10.1177/15910199241289458","DOIUrl":"10.1177/15910199241289458","url":null,"abstract":"<p><strong>Background: </strong>Venous sinus stenting (VSS) is a safe and effective treatment strategy for pulsatile tinnitus (PT) and idiopathic intracranial hypertension (IIH). Although complications are rare, the morbidity associated with the complications is high. Navigating through the venous sinuses poses unique challenges to the interventionalist. There is limited literature regarding device selection to maximize safety and efficiency. We report on the safety and advantages of using a balloon guide catheter (BGC) for venous access in VSS.</p><p><strong>Methods: </strong>Retrospective analysis of all patients undergoing VSS using a BGC over a three-month period.</p><p><strong>Results: </strong>A total of 22 patients were included in the analysis (median age 35; 21 female). The indication for treatment was PT in 10 patients and IIH in 12 patients. The BGC was navigated into the sigmoid and transverse sinuses, enabling successful delivery of the stent in all cases. The BGC balloon was inflated 23 times for navigating past tortuosity or obstructions, and for anchoring. There were no intraprocedural complications.</p><p><strong>Conclusions: </strong>The use of BGC in VSS is safe and feasible. BGCs have features that can be utilized to overcome the unique challenges encountered during VSS.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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