Interventional Neuroradiology最新文献

{"title":"The isolated left gastric artery: A shape-shifting pitfall for neuroangiographers.","authors":"Philippe Gailloud","doi":"10.1177/15910199251324042","DOIUrl":"10.1177/15910199251324042","url":null,"abstract":"","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2885-2888"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial experiences with the target tetra coils: An illustrated case series.","authors":"Jeremy Lynch, Gian Marco Frigerio, Sara Sciacca, Thomas Booth, Martin Lewis, Parthiban Balasundaran, Mohd Shariq, Krishna Bellam-Premnath, Shrikant Londhe, Tufail Patankar, Naga Kandasamy","doi":"10.1177/15910199251343285","DOIUrl":"10.1177/15910199251343285","url":null,"abstract":"<p><p>IntroductionThe management and treatment of intracranial aneurysms have substantially evolved with advancements in neuroendovascular technologies. Among the latest developments are the Target^® Tetra™ coils (Stryker Neurovascular, Kalamazoo, MI, USA). In this non-industry funded illustrated case series we examine the efficacy and safety of Target^® Tetra™ and describe nuances of their usage.MethodsA retrospective two-centre study examined the usage and outcomes of Target^® Tetra™ coil usage in a consecutive series of ruptured and unruptured aneurysms. Data was collected on clinical, technical, and imaging characteristics associated with their usage.ResultsThe dataset consisted of information from a total of 75 patients and 80 aneurysms (mean age 55.7 years). 56/75 (74.7%) aneurysms were treated in the setting of aneurysmal subarachnoid haemorrhage. 80/80 (100%) of the aneurysm treatments were technically successful. 2/80 (2.5%) of the cases encountered technical issues, with 1/80 (1.2%) case of coil migration and 1/80 (1.2%) case where the coil could not be detached. The median clinical follow-up time was 5 months. All-cause mortality was 8%, all occurring in ruptured aneurysms. There was 1/75 (1.3%) rebleed at the time of follow-up. 45% aneurysms patients had imaging follow-up at a median of 5 months. Excluding treatments involving stenting, flow-diversion, and intra-saccular devices the adequate occlusion rate at follow-up was 19/21 (90.5%) for ruptured and 6/6 (100%) for unruptured aneurysms, with an overall rate of 25/27 (92.6%).ConclusionsInitial short-term results suggest the safety and efficacy of the Tetra™ coils. Long-term outcomes in terms of aneurysm occlusion require further study.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2780-2791"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FreeClimb 88 catheter with Tenzing 8 delivery for contact aspiration mechanical thrombectomy of anterior circulation large vessel occlusions.","authors":"Matthew D Alexander, James Caldwell, Shane Sh Lee, Warren T Kim, Joey D English, Jaehyun Kim, Ben J McGuinness, Matthew Page, Nebiyat F Belachew, Jonathan A Grossberg, Daniel Tonetti, Jane Khalife, Hamza Shaikh, Omar Kass-Hout, Marco Colasurdo, Ryan Priest, Bahram Varjavand, Rajkamal S Khangura, Thymur A Chaudhry, Fabio Settecase","doi":"10.1177/15910199241284792","DOIUrl":"10.1177/15910199241284792","url":null,"abstract":"<p><p>PurposeContact aspiration mechanical thrombectomy (CAMT) with 0.088-inch catheters may improve first-pass success rates, but delivery of such catheters can be challenging and limit effectiveness. This study examines the initial multicenter experience using the FreeClimb 88 catheter paired with the Tenzing 8 delivery catheter.Materials and MethodsRetrospective analysis was performed of consecutive patients with large vessel occlusion (LVO) of the internal carotid artery (ICA) or M1 segment of the middle cerebral artery treated with off-label CAMT using the FreeClimb 88 and Tenzing 8 at eight sites participating in the early limited release for these devices. Demographic and procedural variables were collected and analyzed with descriptive statistics and multivariable analysis.ResultsFifty-three consecutive patients were treated. Large vessel occlusion was located in the ICA in 19/53 (35.8%) patients; 34/53 (64.2%) were in the M1 segment. FreeClimb 88 was successfully delivered to the site of occlusion in 50/53 (94.3%) of patients. First-pass TICI 2c or 3 was achieved with FreeClimb 88 delivered by Tenzing 8 in 36 (67.9%) cases. Among cases with successful FreeClimb 88 delivery 9/50 (18.0%) required additional smaller devices to perform thrombectomy of distal occlusions after recanalization of the initial LVO. No complications or symptomatic hemorrhages occurred following thrombectomy.ConclusionContact aspiration mechanical thrombectomy performed for ICA or M1 LVOs using FreeClimb 88 delivered with Tenzing 8 was safe, effective, and efficient in this early experience, with first-pass TICI 2c or 3 was achieved in 68% of patients without procedural complications occurring in any cases.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2461-2469"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142287257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FRED-UK: Multicentre UK experience of FRED and FRED Jr flow re-direction endoluminal device for intracranial aneurysms: 6 months and 1 year clinical and anatomical results.","authors":"Eleanor Taylor, Jonathan Downer, Saleh Lamin, Arun Chandran, Panayiotis Koumellis, Chee Gan, Changez Jadun, Thomas Booth, Anil Gholkar, Joe Leyon, Kyriakos Lobotesis","doi":"10.1177/15910199241302123","DOIUrl":"10.1177/15910199241302123","url":null,"abstract":"<p><p>BackgroundFlow diverting stents (FDS) are an established endovascular treatment for intracranial aneurysms but are reported to have varying rates of adequate occlusion and thromboembolic complications. This study reports clinical safety and efficacy results of the FRED and FRED Jr FDS in clinical practice in the UK at 6 months and 1 year.MethodsThe FRED-UK study is a single arm, multicentre, prospective, observational study conducted in the UK. Safety was reviewed by evaluating morbidity (modified Rankin Score ≤2) and mortality. Efficacy was assessed as adequate occlusion of the treated aneurysm. A clinical event committee and core laboratory independently assessed clinical and anatomical results.ResultsSeven neurointerventional centers treated 61 patients, 57 of which met the full inclusion and exclusion criteria. Of these, 75.4% were treated with FRED and 24.6% with FRED Jr. The aneurysms were located on the cavernous or supraclinoid internal carotid artery (ICA) in 75.4%, on the anterior cerebral artery (ACA) or anterior communicating artery (Acom) in 21.1%, and on the middle cerebral artery (MCA) in 3.5%. 57.9% of aneurysms were small (<10 mm), 40.4% were large (10-24 mm) and 1.8% were giant (≥25 mm). All-cause morbidity and mortality were 0% at 6 and 12 months, and adequate occlusion was 86.7% at 12 months in the per protocol population.ConclusionsThe FRED and FRED Jr devices are safe and efficacious in the treatment of intracranial aneurysms.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2558-2565"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distal versus proximal guide catheter placement on the safety and efficacy of mechanical thrombectomy for acute ischemic stroke in anterior circulation: A systematic review and meta-analysis.","authors":"Trey Seymour, Sherief Ghozy, Seyed Behnam Jazayeri, Dina Ramadan, Nicholas Kendall, Abdelrahman Hamouda, Ali Ahmadzade, Julien Ognard, Alireza Hasanzadeh, Luke Olson, Mobina Motaghian Fard, Ramanathan Kadirvel, David F Kallmes","doi":"10.1177/15910199251380408","DOIUrl":"10.1177/15910199251380408","url":null,"abstract":"<p><p>BackgroundGuide catheter (GC) placement, whether distal or proximal, may influence the efficacy and safety of mechanical thrombectomy (MT) for acute ischemic stroke (AIS) due to large vessel occlusion (LVO). However, definitions of placement and procedural strategies vary across studies, limiting clarity.MethodsWe systematically searched PubMed, Embase, Scopus, and Web of Science from inception to September 1, 2024. Comparative studies of adult patients with anterior circulation AIS-LVO undergoing MT that reported GC placement were included. Both balloon GCs (BGCs) and non-BGCs were eligible. Data were pooled using random-effects models in R. Outcomes included functional independence (modified Rankin Scale 0-2 at 90 days), successful reperfusion (modified thrombolysis in cerebral infarction ≥2b or expanded thrombolysis in cerebral infarction ≥2c), first-pass recanalization (FPR), mortality, puncture-to-recanalization (PTR) time, and complications. Subgroup analyses were performed by thrombectomy technique and catheter type.ResultsSeven retrospective studies comprising 2148 patients (1042 proximal, 1106 distal) were analyzed. Distal placement was associated with higher rates of functional independence (risk ratio (RR): 1.25, 95% confidence interval (CI): 1.10-1.42), successful reperfusion (RR: 1.13, 95% CI: 1.04-1.22), and FPR (RR: 1.35, 95% CI: 1.15-1.58), as well as lower 90-day mortality (RR: 0.52, 95% CI: 0.28-0.82). PTR time was shorter with distal placement (mean difference: -7.7 min, 95% CI: -10.8 to -4.6). No significant differences were observed for symptomatic intracranial hemorrhage (RR: 0.96, 95% CI: 0.55-1.65) or emboli to new territory (RR: 0.84, 95% CI: 0.28-2.52). Benefits were consistent across both BGCs and non-BGCs. Heterogeneity existed in outcome definitions and techniques, and publication bias could not be excluded.ConclusionsDistal GC placement is associated with improved reperfusion, efficiency, and functional outcomes in MT for anterior circulation AIS-LVO, without increased complications. Given the retrospective nature of included studies, anatomic confounding, and inconsistent outcome definitions, findings should be considered preliminary. Multicenter trials are needed to confirm whether catheter position independently predicts MT outcomes.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2742-2754"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients' perceptions on outcomes after mechanical thrombectomy in acute ischemic stroke.","authors":"Shail Thanki, Elliot Pressman, Kassandra M Jade, Ruby Skanes, Ahmad Armouti, Waldo R Guerrero, Kunal Vakharia, Ashwin B Parthasarathy, Kyle Fargen, Eva A Mistry, Shahid M Nimjee, Ameer E Hassan, Maxim Mokin","doi":"10.1177/15910199241227262","DOIUrl":"10.1177/15910199241227262","url":null,"abstract":"<p><p>BackgroundThe modified Rankin Scale (mRS) is a clinician-reported scale that measures the degree of disability in patients who suffered a stroke. Patients' perception of a meaningful recovery from severe stroke, expected value of a stroke intervention, and the effect of disparities are largely unknown.MethodsWe conducted a survey of patients, their family members, and accompanying visitors to understand their personal preferences and expectations for acute strokes potentially eligible for acute endovascular intervention using a hypothetical scenario of a severe stroke in a standardized questionnaire.ResultsOf 164 survey respondents, 65 (39.6%) were the patient involved, 93 (56.7%) were a family member, and six (3.7%) were accompanied visitors (friends, other). Minimally acceptable disability after a stroke intervention was considered as mRS 2 by 42 respondents (25.6%), as mRS 3 by 79 (48.2%), and as mRS 4 by 43 (26.2%) respondents. Race was associated with different views on this question (<i>p</i> < 0.001; Hispanic and Black patients being more likely to accept disability than Caucasian and Asian patients), while sex (<i>p</i> = 0.333) and age (<i>p</i> = 0.560) were not. Sixty-three respondents (38.4%) viewed minimally acceptable probability of improvement with an intervention as over 50%, 57 (34.8%) as 10-50%, and 44 (26.8%) as less than 10%.ConclusionsA wide range of acceptable outcomes were reported regardless of gender or age. However, race was associated with different acceptable outcome. This is an important finding to demonstrate because of the persistent racial and ethnic disparities in the utilization of endovascular therapy for acute stroke in the United States.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2484-2489"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Degree of subarachnoid hemorrhage affects clinical outcome after mechanical thrombectomy for M2 occlusion.","authors":"Fumiaki Oka, Takuma Nishimoto, Naomasa Mori, Akiko Kawano, Hideyuki Ishihara","doi":"10.1177/15910199241270706","DOIUrl":"10.1177/15910199241270706","url":null,"abstract":"<p><p>PurposeThe prognostic relevance of post-mechanical thrombectomy (MT) subarachnoid hemorrhage (SAH) remains controversial. This study aimed to investigate whether the thickness of the SAH clot affects clinical outcomes following MT for M2 occlusion.MethodsA retrospective analysis was conducted on a prospective database of patients who underwent MT for isolated M2 occlusion. Patients were categorized into three groups based on the presence and thickness of SAH. Clinical and angiographical characteristics and outcomes were compared.ResultsOf the 36 patients included, SAH was observed in 15 (42%). When comparing patients with no SAH (grade 0) or thin SAH (grade 1) (N = 28) with those who had thick SAH (grade 2) (N = 8), patients with Grade 2 SAH required a higher number of passes and had a more severe angulation at M2. Patients with SAH Grade 2 had significantly worse NIHSS scores at 24 h (median, 4 vs. 14), but only one patient was identified as having a symptomatic intracranial hemorrhage. Patients with SAH Grade 2 were found to have a lower rate of favorable outcome (modified Rankin scale 0-2) (23% vs. 75%, P = 0.0026) and higher mortality (25% vs. 0%, P = 0.0499) at 90 days.ConclusionThe study found that thick SAH prevents clinical recovery after MT for M2 occlusion, even in cases of successful recanalization, and is associated with an unfavorable outcome. Thick SAH after MT is also linked to an increase in the number of passes and severe angulation at the M2 segment.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2157-2162"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pipeline embolization device as a standalone curative approach for recurrent sigmoid sinus DAVF.","authors":"Vera Sharashidze, Charlotte Chung, Peter Kim Nelson, Maksim Shapiro, Howard Riina, Erez Nossek, Eytan Raz","doi":"10.1177/15910199241282780","DOIUrl":"10.1177/15910199241282780","url":null,"abstract":"<p><p>Dural arteriovenous fistulas (dAVFs) can occur as complications after surgical procedures, especially following the resection of meningiomas near the dural sinus. This case report presents a 74-year-old male who developed a recurrent sigmoid dAVF following meningioma resection. Initially treated with transvenous embolization and middle meningeal artery embolization, the dAVF recurred with worsening clinical symptoms. Conventional treatment options, including sinus sacrifice and transarterial embolization, were unsuitable due to the critical role of the patient's dominant right sigmoid sinus in cerebral venous drainage. Consequently, a reconstructive approach was employed using a pipeline embolization device (PED) construct. The PED successfully occluded the dAVF while preserving the function of the sigmoid sinus. A follow-up angiogram confirmed stable occlusion and normalization of intracranial venous drainage. This case underscores the potential of flow diversion as a viable treatment option for dAVFs, particularly in scenarios where preserving venous sinus function is paramount.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2861-2867"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142287261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"De Novo brain arteriovenous malformations in alcohol-related cirrhosis.","authors":"Amin Yakubu, Neil V Patel, Emanuele Orru, Jonathan Pace, Timo Krings","doi":"10.1177/15910199251342424","DOIUrl":"10.1177/15910199251342424","url":null,"abstract":"<p><p>We report the case of a 38-year-old female with alcohol-related cirrhosis who developed a de novo left hemispheric sylvian fissure pial arteriovenous malformation (AVM) causing recurrent hemorrhages, ultimately necessitating neurosurgical intervention. The case underscores the interplay between chronic systemic disease and vascular abnormalities. We explore the theory of de novo brain AVM (bAVM) formation in the context of liver cirrhosis, chronic inflammation and pro-angiogenic conditions thus shedding a light on the potential underlying pathological mechanisms of bAVM formation. This case also highlights the challenges of managing concurrent neurovascular and systemic conditions.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2909-2915"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An evidence-based pulsatile tinnitus clinical workflow: A systematic review of literature.","authors":"João Victor Sanders, Kiffon Keigher, Marion Oliver, Demetrius Lopes, Krishna Joshi","doi":"10.1177/15910199251380393","DOIUrl":"10.1177/15910199251380393","url":null,"abstract":"<p><p>IntroductionEndovascular management options for pulsatile tinnitus (PT) patients have increased in recent years with promising results. However, standardized endovascular team referral criteria remain limited. We conducted a systematic review and suggested an evidence-based referral protocol for PT patients to the neuroendovascular team.MethodsA literature review was conducted in February 2025 using the PubMed/MEDLINE database. We included English-written studies published in the last 5 years, focusing on PT diagnosis and management. Exclusion criteria included: (1) in vitro or animal studies, (2) studies focused on open surgery approaches, (3) studies addressing only non-PT, and (4) case reports, case series (3-10 cases), commentaries, letters to the editor, editorials, and book chapters.ResultsOur initial search retrieved 257 papers. Of these, 219 were excluded after reading the title and abstract, and an additional 12 were excluded after full-text review. A total of 26 papers were eligible for inclusion in this review and in developing our protocol. After PT diagnosis and imaging, our protocol consists of the following three questions: (1) Is non-invasive imaging suspicious for a dural arteriovenous fistula, high-risk vascular lesions, or idiopathic intracranial hypertension? (2) Despite normal neuroimaging, is there clinical suspicion of a high-risk vascular lesion? (3) Although a low-risk lesion is diagnosed, is PT debilitating? If there is a \"yes\" to any of these questions, referral to the endovascular team is recommended.ConclusionWe suggested an evidence-based referral protocol for PT patients to the neuroendovascular team.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2930-2937"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}