International Journal of Preventive Medicine最新文献

{"title":"Policy and Executive Barriers in Preventing and Eradicating Neglected Tropical Diseases: A Systematic Review.","authors":"Ali Sarabi Asiabar, Alireza Jabbari, Aziz Rezapour, Mohammadreza Jabbari Khanbebin, Pezhman Atafimanesh, Elaheh Mazaheri, Marziye Hadian","doi":"10.4103/ijpvm.ijpvm_251_23","DOIUrl":"10.4103/ijpvm.ijpvm_251_23","url":null,"abstract":"<p><strong>Background: </strong>Tropical diseases inflict many of those living in tropical and subtropical areas each year. These populations because of these diseases suffer considerable financial and human losses. Some of these diseases are known as Neglected Tropical Diseases (NTDs) and they can be highly dangerous. Still, they have not received the attention they need. Given the necessity of eliminating these diseases, the present study is an attempt to examine the reasons for unsuccessful attempts to eliminate diseases like NTDs.</p><p><strong>Methods: </strong>The current study was a systematic analysis of literature on neglected tropical diseases that were found in the databases of the Web of Science, PubMed, Scopus, Science Direct, Pro Quest, Cochrane, and Embase before April 2023. The Critical Appraisal Skills Program (CASP) for articles and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria were used to conduct the study.</p><p><strong>Results: </strong>Based on the systematic search, 3193 papers were found and after the elimination of duplicates and irrelevant ones, a total of 28 articles remained to examine the challenges to eradicate neglected tropical diseases. Four themes were found for the challenges of controlling and eliminating neglected tropic diseases including drawbacks of programs for disease management policies, environmental challenges, executive challenges, and research field challenges. Thirty-six subthemes were obtained in this study, which showed cases such as the presence of immigrants and refugees, weaknesses in public health infrastructure and programs, dynamic epidemiological settings, lack of executive prioritization appropriate to endemic countries, and highly customized research infrastructures. Ending neglected tropical diseases requires an innovative roadmap and global cooperation.</p><p><strong>Conclusions: </strong>To achieve important eradication goals, measures such as acceleration in practice are needed to plan, intensify executive and operational approaches, change application models, innovate processes, and promote culture are needed. In addition, to make possible the elimination of neglected tropical diseases, there is an undeniable need for providing financial, human, and research resources. In addition, there is a need for efficient health infrastructure management, paying attention to migrants and refugees, setting explicit targets, prioritizing based on local conditions, and paying more attention to political and social developments.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"49"},"PeriodicalIF":1.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medication use Pattern among the Elderly in Iran: A Review Article.","authors":"Tayebe Arab Jafari, Parvaneh Abazari, Ali Mohammad Sabzghabaee","doi":"10.4103/ijpvm.ijpvm_142_23","DOIUrl":"10.4103/ijpvm.ijpvm_142_23","url":null,"abstract":"<p><p>Suffering from multiple diseases simultaneously has turned the elderly into the largest group of drug users in society. On the other hand, the situation of the pattern of drug consumption by the elderly vulnerable group has received less attention. The present study was conducted to determine the pattern of drug consumption among the elderly in the country between 2010 and 2023. The present study is a narrative review. Based on the defined keywords, a targeted search has been conducted in available Persian and English databases. 114 articles were found, and by removing duplicates and appraisal of abstracts based on the inclusion criteria and the purpose of the research, finally, 14 articles (8 English and 6 Persian) were analyzed. The most common drugs used by the elderly in Iran were cardiovascular, pain relievers, and digestive drugs, and more than 90% of the drugs were taken orally. Also, according to the findings, polypharmacy is common among the elderly in the country, and with the increase in the number of drugs used, self-administration of drugs, non-adherence to drugs, and the use of potentially inappropriate drugs have also increased. Previous recovery experience and easy access to medicine are also mentioned as the most important factors of self-treatment. The use of drugs by the Iranian elderly does not follow a logical pattern, which can not only lead to serious consequences in the health status of this age group but will also have significant economic and social consequences for the elderly and their families, the health system, and the society.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"51"},"PeriodicalIF":1.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142636053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case-control Study on the Association of Fruit and Vegetable Consumption with Risk of Breast Cancer.","authors":"Reza Ramezani, Leila Azadbakht, Sanaz Benisi-Kohansal, Ahmad Esmaillzadeh, Alireza Milajerdi","doi":"10.4103/ijpvm.ijpvm_129_23","DOIUrl":"10.4103/ijpvm.ijpvm_129_23","url":null,"abstract":"<p><strong>Background: </strong>Limited data are available linking dietary intake of fruit and vegetables to breast cancer, in particular among the Middle Eastern population. The present study was done to investigate the association of fruit and vegetable consumption with the risk of breast cancer in Iranian adult women.</p><p><strong>Methods: </strong>Dietary intake of fruit and vegetables was assessed using a validated 106-item Willett-format semi-quantitative dish-based food frequency questionnaire. Logistic regression was used to determine the association between fruit and vegetable consumption and breast cancer. Women aged >30 years, residing in Isfahan, Iran from July 2013 to July 2015. Breast cancer was diagnosed during the maximum of the last 6 months by physical examination and mammography findings.</p><p><strong>Results: </strong>Overall, data on 350 cases and 700 controls were analyzed. After controlling for potential confounders, participants with the highest dietary intake of fruits had higher odds of breast cancer than those with the lowest intake (odds ratio [OR]: 8.23; 95% confidence interval [CI]: 4.37-15.50), while those who consumed highest amounts of vegetables were less likely to have breast cancer than their counterparts (OR: 0.12; 95% CI: 0.06-0.24). Although no significant associations were found between dietary intakes of fruits and vegetables and risk of breast cancer in premenopausal women, significant positive association between fruit consumption and breast cancer (OR: 16.80; 95% CI: 7.80, 36.21; <i>P</i> < .001) was observed in postmenopausal women.</p><p><strong>Conclusions: </strong>We found an inverse association between dietary intake of vegetables and breast cancer. Fruit consumption was significantly associated with greater odds of breast cancer in this study.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"56"},"PeriodicalIF":1.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physician Suicide Code as a Health Warning.","authors":"Mohammad-Rafi Bazrafshan, Omid Barghi","doi":"10.4103/ijpvm.ijpvm_5_24","DOIUrl":"10.4103/ijpvm.ijpvm_5_24","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"44"},"PeriodicalIF":1.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minocycline Acts as a Neuroprotective Agent Against Tramadol-Induced Neurodegeneration: Behavioral and Molecular Evidence.","authors":"Mina Gholami, Zahra Ghelichkhani, Reza Aghakhani, Daniel J Klionsky, Ozra Motaghinejad, Majid Motaghinejad, Mohammad Kazem Koohi, Jalal Hassan","doi":"10.4103/ijpvm.ijpvm_10_24","DOIUrl":"10.4103/ijpvm.ijpvm_10_24","url":null,"abstract":"<p><strong>Background: </strong>Previous evidence indicates that tramadol (TRA) can lead to neurodegenerative events and minocycline (MIN) has neuroprotective properties.</p><p><strong>Aim of the study: </strong>The current research evaluated the neuroprotective effects of MIN for TRA-promoted neurodegeneration.</p><p><strong>Methods: </strong>Sixty adult male rats were placed into the following groups: 1 (received 0.7 ml/rat of normal saline, IP), 2 (received 50 mg/kg of TRA, i.p.), 3, 4, 5 (administered TRA as 50 mg/kg simultaneously with MIN at 20, 40, and 60 mg/kg, IP, respectively), and 6 (received MIN alone as 60 mg/kg, IP). The treatment procedure was 21 days. An open field test (OFT) was used to measure motor activity and anxiety-related behavior. Furthermore, oxidative stress; hippocampal inflammation; apoptotic parameters as well as activity of mitochondrial complexes I, II, III, and IV; ATP levels; and mitochondrial membrane potential (MMP) were evaluated. In addition, histomorphological alteration was assessed in two regions of the hippocampus: Cornu Ammonis (CA1) and dentate gyrus (DG).</p><p><strong>Results: </strong>MIN treatment could inhibit TRA-induced anxiety and motor activity disturbances (<i>P</i> < 0.05). In addition, MIN could attenuate reactive oxygen species (ROS), H₂O₂, oxidized glutathione (GSSG), and malondialdehyde (MDA) level (<i>P</i> < 0.05), while there was increased reduced glutathione (GSH), total antioxidant capacity (TAC), ATP, MMP, and BCL2 levels (<i>P</i> < 0.05) and also elevation of SOD, GPX, GSR (<i>P</i> < 0.05), and mitochondrial complexes I, II, III, and IV activity (<i>P</i> < 0.05) in TRA-treated rats. In consistence with these findings, MIN could reduce TNF/TNF-α, IL1B/IL1-β, BAX, and CASP3 levels (<i>P</i> < 0.05) in TRA-treated rats. MIN also restored the quantitative (<i>P</i> < 0.05) and qualitative histomorphological sequels of TRA in both CA1 and DG areas of the hippocampus.</p><p><strong>Conclusions: </strong>MIN probably has repositioning capability for inhibition of TRA-induced neurodegeneration via modulation of inflammation, oxidative stress, apoptosis, and mitochondrial disorders.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"47"},"PeriodicalIF":1.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preventive Effects of Crocin, a Key Carotenoid Component in Saffron, Against Nicotine-Triggered Neurodegeneration in Rat Hippocampus: Possible Role of Autophagy and Apoptosis.","authors":"Mina Gholami, Daniel J Klionsky, Majid Motaghinejad","doi":"10.4103/ijpvm.ijpvm_41_23","DOIUrl":"10.4103/ijpvm.ijpvm_41_23","url":null,"abstract":"<p><strong>Background: </strong>Nicotine is a behavioral stimulant that in high doses, through the neuro-inflammatory and oxidative stress pathway, can induce apoptosis and autophagy leading to cell death. Previous data indicate that crocin has neuroprotective properties. The aim of the current study is to investigate crocin's neuroprotective effects against nicotine-triggered neuro-inflammation, apoptosis, and autophagy in rat hippocampus.</p><p><strong>Methods: </strong>Seventy adult male Wistar rats were divided into the following seven groups: Group one received normal saline (0.2 ml/rat), group two was treated with nicotine 10 mg/kg intraperitoneally, groups 3 to 6 were treated simultaneously with nicotine and crocin (10, 20, 40, and 80 mg/kg, intraperitoneally), group 7 was treated with crocin-alone (80 mg/kg, intraperitoneally). The period of the mentioned agent administration was 21 days. On the 22^nd day, an open field test (OFT) was used for evaluation of anxiety and motor activity changes. Inflammatory and oxidative stress factors and also apoptosis and autophagy biomarkers were evaluated.</p><p><strong>Results: </strong>All mentioned doses of crocin could decrease the nicotine-induced OFT behavioral changes. Crocin also could decrease levels of hippocampal TNF/TNF-α (tumor necrosis factor), IL1B/IL-1β (interleukin 1 beta), oxidized glutathione (GSSG), unphosphorylated and phosphorylated forms of JNK, BECN1 (beclin 1), BAX (BCL2 associated X, apoptosis regulator), and phosphorylated/inactive forms of BCL2 (BCL2 apoptosis regulator) in nicotine-dependent rats. Crocin treatments also caused increases in the reduced form of glutathione (GSH) content and activity of CAT (catalase) and mitochondrial complex enzymes in nicotine-addicted subjects.</p><p><strong>Conclusions: </strong>Crocin can modulate JNK-BCL2-BECN1 or JNK-BCL2-BAX signaling pathways and reduce neuronal oxidative stress, neuro-inflammation, and mitochondrial respiratory chain enzymes and exert neuroprotective effects against nicotine-induced neurodegeneration.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"46"},"PeriodicalIF":1.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Efficacy of COVID-19 Vaccines Among Patients with Multiple Sclerosis: Letter to Editor.","authors":"Omid Mirmosayyeb, Elham Moases Ghaffary, Aram Zabeti, Vahid Shaygannejad","doi":"10.4103/ijpvm.ijpvm_11_24","DOIUrl":"10.4103/ijpvm.ijpvm_11_24","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"45"},"PeriodicalIF":1.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational Exposure to Artificial Ultraviolet Radiation from Welding in Australia.","authors":"Lin Fritschi, Tim Driscoll, Ha Nguyen, Renee N Carey","doi":"10.4103/ijpvm.ijpvm_250_23","DOIUrl":"10.4103/ijpvm.ijpvm_250_23","url":null,"abstract":"<p><strong>Background: </strong>Artificial ultraviolet radiation (UVR) is produced during welding and can cause damage to both the eyes (ocular) and the skin (dermal). We aimed to investigate the protection used by welders to reduce their exposure to ocular and dermal UVR.</p><p><strong>Methods: </strong>We conducted a cross-sectional online survey in Australia that asked welders about their welding tasks and the control measures they used to protect against UVR exposure.</p><p><strong>Results: </strong>There were 634 respondents, of whom 411 undertook welding themselves, 36 supervised other welders, and 130 both supervised and welded. Dermal UVR exposure occurred in 7.8% of welders and 14.4% of supervisors, whereas ocular UVR exposure occurred in 16.8% of welders and 33.1% of supervisors. The use of personal control measures was much lower among supervisors than welders; however, the presence of warning signs or barriers was reported more often by supervisors.</p><p><strong>Conclusions: </strong>Despite the well-known acute and chronic effects of exposure to UVR from welding, there are still many welders and supervisors who do not use adequate protection.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"43"},"PeriodicalIF":1.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes Care: An Online Web-Based Tool for Improving the Health Outcomes of Type 2 Diabetes Mellitus Patients: A Longitudinal Study.","authors":"Deepak Anil, D Sunil Kumar, S Rajendra Prasad, Arun Gopi, Hari Prakash, Deepika Yadav, M R Narayana Murthy","doi":"10.4103/ijpvm.ijpvm_121_23","DOIUrl":"10.4103/ijpvm.ijpvm_121_23","url":null,"abstract":"<p><strong>Background: </strong>Diabetes is a chronic medical condition with severe complications, mainly caused by unhealthy lifestyles in genetically susceptible individuals. There has been a growing interest in the role of mobile health technologies in achieving better self-efficacy in managing diabetes. This study attempts to assess the impact of a web-based model on improving the diabetes status among Type 2 diabetic patients attending a tertiary care hospital in southern India.</p><p><strong>Methods: </strong>A longitudinal study was conducted among patients with type 2 diabetes attending the outpatient department of a tertiary care hospital in Mysuru, southern India, for 6 months. Diabetes Care (https://www.diabetes-care.co.in/), which is an online website that can be used as a risk prediction tool for uncontrolled diabetes and recommends lifestyle changes, was used by 456 diabetes patients for 6 months. We assessed the change in glycosylated haemoglobin levels at the beginning and after 6 months of using the software.</p><p><strong>Results: </strong>The mean HbA1c value at the start of the study was 8.039% ± 1.981. The HbA1c value assessed after 6 months post-intervention showed an improvement of 7.794% ± 1.853 with a mean difference of 0.245. A paired T-test showed a statistically significant association with a <i>P</i> value of 0.049.</p><p><strong>Conclusions: </strong>Evidence from this study suggests that intervention using a web-based model focusing on risk prediction and educational intervention showed an improvement in the diabetic status of the patients with T2DM.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"48"},"PeriodicalIF":1.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"History of Mental Health in the Philippines: A Response to the Call to Revolutionize Mental Health Services Toward Positive Well-being.","authors":"Justin Vianey M Embalsado","doi":"10.4103/ijpvm.ijpvm_362_23","DOIUrl":"https://doi.org/10.4103/ijpvm.ijpvm_362_23","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"40"},"PeriodicalIF":1.7,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}