International Journal of Preventive Medicine最新文献

{"title":"Insulin Resistance Mediates the Association Between Vitamin D and Non-Alcoholic Fatty Liver Disease.","authors":"Caiyan Zou, Xuekui Liu, Maosheng He, Yan Sun, Yiquan Sang, Gangshan Peng, Yamei Ma, Houfa Geng, Jun Liang","doi":"10.4103/ijpvm.ijpvm_221_23","DOIUrl":"10.4103/ijpvm.ijpvm_221_23","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D (VD) deficiency and insulin resistance (IR) increase the risk of non-alcoholic fatty liver disease (NAFLD), but few studies have explored the potential mechanisms by which IR mediates the association between VD and the pathogenesis of NAFLD at the genetic level using publicly available databases.</p><p><strong>Methods: </strong>This is a cross-sectional study, and we utilized the National Health and Nutrition Examination Survey (NHANES) dataset, as well as data from GSE200765 obtained from the Gene Expression Omnibus (GEO) website. A total of 723 individuals who had completed liver ultrasound examination and the detection of VD levels were included in the final analysis. A gene expression dataset, GSE200765, was also downloaded from the GEO website, to explore the potential mechanism of VD and NAFLD.</p><p><strong>Results: </strong>In the NHANES data, covariates significantly differed in four VD categories, and the controlled attenuation parameter (CAP), vibration-controlled transient elastography-liver stiffness measurement (VCTE-LSM), and IR were reduced with an increase in VD levels. Mediation analysis revealed that IR mediated the association between VD and both CAP and LSM, and the estimated mediation effects were 29.0% and 39.8%, respectively. Bioinformatics analysis showed that seven differentially expressed genes (DEGs) (solute carrier family 2 member 2 [SLC2A2], protein phosphatase 1 regulatory subunit 3E [PPP1R3E], CAMP responsive element binding protein 3-like 3 [CREB3L3], Interleukin-6 [IL-6], peroxisome proliferator-activated receptor gamma coactivator 1-alpha [PPARGC1A], nuclear factor kappa B inhibitor alpha [NFKBIA], and phosphoenolpyruvate carboxykinase 2 [PCK2]) were enriched in the IR pathway in comparison groups (VD group vs. lipid group), suggesting that VD improved NAFLD via changed IR.</p><p><strong>Conclusions: </strong>VD deficiency and IR were the risk factors for NAFLD, and increased VD levels improved the status of NAFLD. The underlying mechanism may be that elevated VD levels reduced IR, which improved the expression of DEGs involved in the IR pathway.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"77"},"PeriodicalIF":1.7,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designing a Framework for Evaluating the Scientific Productions.","authors":"Ali Norouzi, Parastoo Parsaei-Mohammadi, Ehsan Geraei, Firoozeh Zare-Farashbandi","doi":"10.4103/ijpvm.ijpvm_162_24","DOIUrl":"10.4103/ijpvm.ijpvm_162_24","url":null,"abstract":"<p><strong>Background: </strong>Evaluation of scientific productions to attract, maintain, and promote faculty members is one of the necessary processes of academic societies and is of interest to policy makers in the field of higher education. This study aimed to provide a uniform and native framework for evaluating the scientific productions of researchers in the fields of science and health in Iran.</p><p><strong>Methods: </strong>The current research used the single-stage fuzzy Delphi technique and AHP. The research community comprised 50 top scientific experts and researchers from the country. The data collection tool was a researcher-made checklist obtained from the review of literature and laws and regulations of Iranian universities and research institutions.</p><p><strong>Results: </strong>Data analysis led to the identification, prioritization and weighting of eleven criteria and 124 items for the intended framework, which are, respectively, author's authority (scientific leaders) (15 items); database used in calculating the index (3 items); Innovation and technological impact (18 items); Gaining rank in national and international festivals related to the specialized field (6 items); Citations (7 items); subject area (3 items); level of cooperation (15 items); Types of scientific productions (54 items); scientific age (3 items); Evaluating, refereeing and monitoring of research, technology and innovation activities (2 items) Author`s role and position (1 item).</p><p><strong>Conclusion: </strong>The final framework obtained for evaluating Iranian researchers has 11 criteria and 124 items that can be used to compile an author-centered and native scientometrics index that leads to the same evaluation of health and science researchers.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"70"},"PeriodicalIF":1.7,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimorbidity and Depression Increase Prevalence of Frailty of Community-dwelling Indonesian Older Adults: Indonesia Care Networks Study.","authors":"Yvonne Suzy Handajani, Elisabeth Schroeder-Butterfill, Eef Hogervorst, Yuda Turana, Antoninus Hengky","doi":"10.4103/ijpvm.ijpvm_160_23","DOIUrl":"10.4103/ijpvm.ijpvm_160_23","url":null,"abstract":"<p><strong>Background: </strong>Older adults with frailty have an increased risk of multiple negative health outcomes, such as disability, falls, and morbidity when exposed to physical stressors. The present study investigated the prevalence of frailty and associated risk factors among community-dwelling Indonesian older adults in several districts in Jakarta, Indonesia.</p><p><strong>Methods: </strong>This cross-sectional study was done in several urban villages in Jakarta, Indonesia. It involved community-dwelling Indonesian older adults aged 60 and over. Sociodemographic and multiple health data were assessed and measured by a trained interviewer. Frailty was evaluated using Fried's criteria.</p><p><strong>Results: </strong>The data analysis found a 14.7% prevalence of frailty among 518 participants. Multivariate analysis showed that frailty was independently associated with females (OR 3.62, 95% CI: 1.73-7.55), having multimorbidity (OR 2.01, 95% CI: 1.21-3.35), and clinical depression (OR 2.13, 95% CI: 1.24-3.65).</p><p><strong>Conclusions: </strong>Early interventions in younger older adults, especially women in their early 50s or 60s, might decrease frailty risk over age 60. Controlling chronic disease and better mental education and support to reduce depression risk could reduce frailty risk.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"69"},"PeriodicalIF":1.7,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation, Validity, and Reliability of Depression Literacy Questionnaire in Iranian Young Adults.","authors":"Fatteme Raiisi, Mohamad Ebrahimi, Fahimeh Ghahvehchi Hosseini, Kosar Jafari, Fatemeh Rahmati","doi":"10.4103/ijpvm.ijpvm_311_23","DOIUrl":"10.4103/ijpvm.ijpvm_311_23","url":null,"abstract":"<p><strong>Background: </strong>Depression literacy has notable advantages in the early identification and treatment of depression. The current study was conducted with the aim of translating and investigating the validity and reliability of the Depression Literacy Questionnaire (D-Lit) in Iranian young adults.</p><p><strong>Methods: </strong>The current study entailed a descriptive-analytical study in which the translation, validation, and preparation of the Persian version of D-Lit were conducted. It had two stages: translation and validation. In order to check the composite reliability, the statistical population consisted of Iranian adults in the city of Mashhad, and 300 people participated in this study in the form of a census. The content validity ratio (CVR) and content validity index (CVI) indices were used for content validity.</p><p><strong>Results: </strong>The results of the content validity evaluation of this questionnaire indicated that both the CVR and CVI indices have higher-than-average coefficients (0.78 and 0.83). Furthermore, the Cronbach's alpha value for the components of the D-Lit was found to be higher than 0.70. In the present study, the questionnaire's reliability was assessed using the intra-cluster correlation coefficient (ICC), and the difficulty coefficient for the whole questionnaire and its sub-components was at a favorable level. Out of 22 questions, 17 questions of this questionnaire were retained and questions 1, 17, and 22 were removed due to low CVR and CVI in the validity stage, and questions 5 and 13 were removed due to common factor load in the factor analysis stage.</p><p><strong>Conclusion: </strong>According to the content validity and reliability in this study, this tool can be used to identify underlying factors, etiology, and treatment of depression.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"72"},"PeriodicalIF":1.7,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Different Dietary Carbohydrate and Risk of Depression, Anxiety, and Stress Among Female Adolescents.","authors":"Niayesh Naghshi, Asal N Tehrani, Samira Rabiei, Vahideh Behrouz, Zahra Yari","doi":"10.4103/ijpvm.ijpvm_291_23","DOIUrl":"10.4103/ijpvm.ijpvm_291_23","url":null,"abstract":"<p><strong>Purpose: </strong>Mental disorders account for a large part of the burden of disease in young population. The present study aimed to investigate the relationship between carbohydrate intakes and the risk of depression, anxiety, and stress among female adolescents.</p><p><strong>Methods: </strong>In this cross-sectional study, 263 female adolescents aged 15-18 years participated. Depression, anxiety, and stress scores were determined by DASS-21 (Depression Anxiety Stress Score-21 items) questionnaire, and dietary intakes were assessed using a validated 168-item food frequency questionnaire. Crude and multivariable-adjusted odds ratios (OR) and 95% confidence intervals (CIs) were estimated through logistic regression analysis.</p><p><strong>Results: </strong>Adolescents with depression consumed more glucose and sucrose and less lactose compared to adolescents without depression. After adjustment for all confounders, higher intakes of glucose and sucrose were significantly associated with increased risk of depression (OR _glu = 1.3, <i>P</i> = 0.035 and OR _suc = 1.41, <i>P</i> = 0.034), anxiety (OR _glu = 1.3, <i>P</i> = 0.019 and OR _suc = 1.81, <i>P</i> = 0.027), and stress (OR _glu = 1.41, <i>P</i> = 0.046 and OR _suc = 1.8, <i>P</i> = 0.044). In addition, increasing lactose intake was significantly associated with reducing the risk of depression (OR = 0.96, <i>P</i> = 0.013) and stress (OR = 0.96, <i>P</i> = 0.015).</p><p><strong>Conclusions: </strong>This study found significant associations between dietary carbohydrate intake and mental disorders among female adolescent.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"71"},"PeriodicalIF":1.7,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamics of Dairy Product Consumption, Confounding Factors, and Their Influence on the Risk of Type 2 Diabetes.","authors":"Sanjeev K Gautam, Bimlesh Kumar, Prashant Kumbhar Narendra K Pandey","doi":"10.4103/ijpvm.ijpvm_356_23","DOIUrl":"10.4103/ijpvm.ijpvm_356_23","url":null,"abstract":"<p><p>It has long been debated whether or not dairy consumption increases the risk of type 2 diabetes (T2D). This link has been assessed by a large number of case-control studies, prospective cohort studies, systematic reviews, and meta-analyses. The majority of their studies demonstrated an inverse relationship between the risk of T2D and dairy consumption. It is yet unclear how dairy products specifically contribute to metabolic diseases like type 2 diabetes. However, a surprising number of studies have indicated either no association or a positive correlation between the development of type 2 diabetes and certain dairy products. The objective of this narrative review is to collate research findings from diverse geographical contexts, exploring the impact of dairy product consumption on the incidence and risk of Type 2 diabetes (T2D). This review includes studies that addressed this research issue and were released between the years 2000 and 2023. This will help the public draw logical inferences and validate the body of recent research. To shed light on this matter, the writers conduct a comprehensive search of electronic scientific databases such as PubMed, Scopus, and Web of Science. Thus, this review emphasizes the connection between the usage of different dairy products and the risk of T2D. After controlling for confounding variables, this review indicates that the relationship between the incidence of type 2 diabetes and consumption of dairy products is context-dependent. In conclusion, not all dairy products help to prevent type 2 diabetes. There is no association between most other dairy products and T2D, while in some cases benefits of yogurt and other low-fat dairy products have been reported.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"68"},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Childhood High Adiposity has no Advantage for Height in Adulthood: Cross-Sectional Studies in Indonesian Children to Young Adults.","authors":"Janatin Hastuti, Neni Trilusiana Rahmawati, Madarina Julia","doi":"10.4103/ijpvm.ijpvm_95_23","DOIUrl":"10.4103/ijpvm.ijpvm_95_23","url":null,"abstract":"<p><strong>Background: </strong>Childhood obesity is associated with faster linear growth; nonetheless, its benefit to the mature height of Indonesian children is questionable. This study aimed to evaluate the relationship between adiposity and height growth of Indonesian children, adolescents, and young adults aged 7 to 23 years.</p><p><strong>Methods: </strong>Height and skinfolds at triceps, subscapular, suprailiac, and calf were measured in 2,520 children, adolescents, and young adults aged 7 to 23 years (boys = 1,116, girls = 1,404). Central adiposity (subscapular and suprailiac skinfolds) and peripheral adiposity (triceps and calf skinfolds) were projected against heights in each age group. The ANCOVA test and partial correlation were used for statistical analysis.</p><p><strong>Results: </strong>With the exception of ages 8 to 12 years, boys were always taller than girls after controlling for age and central or peripheral adiposity. Boys with higher central and peripheral adiposity were taller than their peers up to the age of 17 (<i>r</i> = 0.30-0.72, <i>P</i> < 0.05, <i>P</i> < 0.01). Girls with central adiposity grew taller than their thinner peers until the age of 14 (<i>r</i> = 0.17-0.50, <i>P</i> < 0.05, <i>P</i> < 0.01), whereas girls with peripheral adiposity benefit from this advantage over a more extended period of time. Afterward, adiposity did not offer any benefit on heights.</p><p><strong>Conclusions: </strong>Children with high adiposity who were taller at an earlier age have no significant advantage over their thinner peers in terms of adult height.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"64"},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Locus of Hope-Based Intervention to Address Mental Health Services Gap in Promoting Positive Mental Health.","authors":"Justin Vianey M Embalsado","doi":"10.4103/ijpvm.ijpvm_357_23","DOIUrl":"10.4103/ijpvm.ijpvm_357_23","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"60"},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy of Zinc Gluconate Supplementation in the Improvement of Malnutrition Indices and Skin Abnormalities in Hemodialysis Patients: A Randomized Clinical Trial.","authors":"Mohammad Tavassoli, Shahrzad Shahidi, Gholamreza Askari, Naser Tavakoli, Cain C T Clark, Mohammad Hossein Rouhani","doi":"10.4103/ijpvm.ijpvm_206_23","DOIUrl":"10.4103/ijpvm.ijpvm_206_23","url":null,"abstract":"<p><strong>Background: </strong>Hemodialysis patients often suffer from several complications such as malnutrition and skin abnormalities. We hypothesized that zinc supplementation may improve these complications. The aim of the present study was to examine the effects of zinc gluconate supplementation on malnutrition and skin abnormalities.</p><p><strong>Methods: </strong>In this parallel randomized, double-blind, clinical trial, patients in the zinc group received 210 mg zinc gluconate (equivalent to 30 mg elemental zinc) per day. Skin abnormalities (i.e. xerosis and pruritus), body composition, anthropometric variables, handgrip strength, and appetite (including hunger, fullness, desire to eat, and prospective food consumption) were measured at the beginning and end of the study.</p><p><strong>Results: </strong>Eighty-seven hemodialysis patients were randomly assigned to the zinc (<i>n</i> = 44) or placebo (<i>n</i> = 43) group for 12 weeks, After this period, 75 patients (<i>N</i> = 38 in the zinc group and 37 in the placebo group) remained in the study. In this study, no specific side effects of zinc supplementation were observed and twelve participants were lost to follow-up (<i>n</i> = 6 in each group) because of migration, kidney transplantation, death, dialysis access infection, and personal reasons. Zinc supplementation had beneficial effects on hunger) 95% CI: 9/55 (3/67-15/42)), desire to eat) 95% CI: 7/03 (1/82-12/24)), and prospective food consumption) 95% CI: 3/46 (0/3-14/1)) compared with placebo. Also, zinc improved pruritus) 95% CI: -0/52 (-0/82 to - 0/22)). We observed no changes in body composition, anthropometric variables, handgrip strength, and xerosis in the zinc group compared with the placebo.</p><p><strong>Conclusions: </strong>This randomized clinical trial showed that zinc supplementation yielded beneficial effects on appetite and pruritus in hemodialysis patients.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"63"},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Governments! Remember Cancer Too!","authors":"Amir Hossein Tabatabaie, Negar Amiri, Iman Hafizi-Rastani","doi":"10.4103/ijpvm.ijpvm_94_24","DOIUrl":"10.4103/ijpvm.ijpvm_94_24","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"15 ","pages":"59"},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11687690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}