International Journal of Preventive Medicine最新文献

{"title":"The Effect of 4 Weeks Aerobic Exercise Training with Detraining Courses in Various Prevention Phases on BCl-2 and BAX Genes Expression and Proteins.","authors":"Yousef Shahvali Koohshoori,&nbsp;Sayed M Marandi,&nbsp;Mehdi Kargarfard,&nbsp;Golnaz Vaseghi,&nbsp;Seyed J Moshtaghian","doi":"10.4103/ijpvm.ijpvm_15_21","DOIUrl":"https://doi.org/10.4103/ijpvm.ijpvm_15_21","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the effect of aerobic exercise with detraining in different phases of prevention on BCL2 Associated X (BAX) and B-cell lymphoma 2 (BCl-2) gene expression and proteins.</p><p><strong>Methods: </strong>For this purpose, 32 female Balb-c mice (18-20 g) were purchased and randomly assigned to primordial prevention (A), primary prevention (B), secondary prevention (C), and control (D). A group performed aerobic exercise for 4 weeks, after 4T1 cells injection detrained for 8 weeks. Group B performed aerobic exercise for 4 weeks immediately after injecting 4T1 cells and then detrained for 4 weeks. In C group, the 4T1 cells were first injected and did not perform any activity for 4 weeks, followed by 4 weeks of aerobic exercise. Forty-eight hours after the last training session and detraining courses, after anesthesia, sacrificing, and tissue removal, were performed. Reverse transcription polymerase chain reaction (RT PCR) was used to measure gene expression and Western blot (WB) was used to measure protein content. One-way Analysis of variance (ANOVA) test was used to analyze data.</p><p><strong>Results: </strong>The results showed that aerobic exercise in A, B, and C groups compared to D group reduced BCl-2 gene expression and protein and increased BAX gene expression and protein.</p><p><strong>Conclusions: </strong>Therefore, exercise can cause apoptosis in tumor cells by increasing pre-apoptotic factors and decreasing antiapoptotic factors in tumor cells, and consequently improving the disease status.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"79"},"PeriodicalIF":2.1,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/19/24/IJPVM-14-79.PMC10580205.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 Pandemic Infection Control and Instantaneous Contact Tracing Using Mobile Phone Apps.","authors":"Rujittika Mungmunpuntipantip,&nbsp;Viroj Wiwanitkit","doi":"10.4103/ijpvm.ijpvm_38_21","DOIUrl":"https://doi.org/10.4103/ijpvm.ijpvm_38_21","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"77"},"PeriodicalIF":2.1,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/43/8a/IJPVM-14-77.PMC10580187.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic and Clinical Characteristics of Familial and Sporadic Multiple Sclerosis Patients.","authors":"Shahrzad Mokhtari, Shakiba Houshi, Omid Mirmosayyeb, Mahdi Barzegar, Alireza Afshari-Safavi, Majid Ghasemi, Vahid Shaygannejad","doi":"10.4103/ijpvm.ijpvm_187_22","DOIUrl":"10.4103/ijpvm.ijpvm_187_22","url":null,"abstract":"<p><strong>Background: </strong>Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating, immune-mediated disease of the central nervous system. It is still unestablished whether heredity correlates with the disease's progression and severity.</p><p><strong>Methods: </strong>This study includes the patients with MS seen in the MS clinic of Kashani Hospital, affiliated with Isfahan University of Medical Sciences, from January 2019 to January 2020. We gathered data regarding the demographic and clinical characteristics, such as type of disease and family history of MS. Patients were grouped based on having relatives with MS. We compared demographic and clinical characteristics between those with a family history of MS (familial MS: FMS) and those without a family history of MS (sporadic MS: SMS).</p><p><strong>Results: </strong>We included 2,929 MS patients, 523 (17.2%) with FMS and 2,406 (82.8%) with SMS. Patients with FMS were found to have active lesions in the thoracic spine more frequently than those with SMS (<i>P</i> = 0.022). We also found differences in the distribution of gender (<i>P</i> = 0.036) and the frequency of having active brain lesions (<i>P</i> = .024) among patients with FMS and SMS. No difference was found between the demographic/clinical characteristics and the number of affected relatives in the family.</p><p><strong>Conclusions: </strong>Significant differences were found among different groups of patients in terms of demographical and clinical characteristics.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"86"},"PeriodicalIF":1.7,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4a/4f/IJPVM-14-86.PMC10580190.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroprotective Effects of Selegiline Agent Methamphetamine-Prompted Mood-Related Behavior Disorder Mediated Via 5-HT₂ and D₂ Receptors.","authors":"Mina Gholami,&nbsp;Neda Kaviani,&nbsp;Majid Motaghinejad,&nbsp;Luis Ulloa","doi":"10.4103/ijpvm.ijpvm_42_22","DOIUrl":"https://doi.org/10.4103/ijpvm.ijpvm_42_22","url":null,"abstract":"<p><strong>Background: </strong>Many previous studies demonstrated that methamphetamine (METH) abuses can cause mood-related behavioral changes. Previous studies indicated neuroprotective effects of Selegiline.</p><p><strong>Methods: </strong>Seventy male Wistar rats were randomly divided into eight groups (10 rats in each group). Group 1 and Group 2 received normal saline and methamphetamine (10 mg/kg) for 21 days, respectively. Groups 3, 4, and 5 were treated simultaneously with methamphetamine and Selegiline with doses of 10, 15, and 20 mg/kg for 21 days. Groups 6 and 7 are methamphetamine-dependent groups which received 15 mg/kg of Selegiline with haloperidol (as D₂ receptor antagonist) and trazodone (as 5-HT₂ receptor antagonist) for 21 days, respectively. In days 23 and 24, elevated plus maze (EPM) and open-field test (OFT) were conducted to assess motor activity and mood (anxiety and depression) levels.</p><p><strong>Results: </strong>METH as 10 mg/kg causes reduction of rearing number, ambulation distances, time spent in central square and also number of central square entries in OFT. Also METH administration causes decreases of time spent in open arm and number of open arm entries and increases of time spent in closed arm and number of closed arm entries in EPM. In contrast, Selegiline (of 10, 15, and 20 mg/kg) inhibited behavioral effects of methamphetamine in both OFT and EPM. Also administration of haloperidol and trazodone inhibited these behavioral protective effects of Selegiline and caused decrease of OFT behaviors (rearing number, ambulation distances, time spent in central square, and also number of central square entries) and also caused decreases of spend times in open arm, number of open arm entries, and also increased closed arm time spending and number of entries in closed arm in EPM.</p><p><strong>Conclusions: </strong>Current research showed that Selegiline via mediation of D2 and 5-HT₂ receptors inhibits METH-induced neurobehavioral changes, mood-related behavior, and motor activity disturbances.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"78"},"PeriodicalIF":2.1,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4b/7f/IJPVM-14-78.PMC10580189.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancerous Patient, COVID-19 Vaccination, Blood Viscosity and Stroke-Like Complication.","authors":"Beuy Joob,&nbsp;Viroj Wiwanitkit","doi":"10.4103/ijpvm.ijpvm_217_21","DOIUrl":"https://doi.org/10.4103/ijpvm.ijpvm_217_21","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"87"},"PeriodicalIF":2.1,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/d8/IJPVM-14-87.PMC10580184.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diamond, the New Form That COVID-19 Chose for Nurses!","authors":"Mohammad-Rafi Bazrafshan,&nbsp;Hakime Akbari,&nbsp;Masoud Mohammadi","doi":"10.4103/ijpvm.ijpvm_524_21","DOIUrl":"https://doi.org/10.4103/ijpvm.ijpvm_524_21","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"88"},"PeriodicalIF":2.1,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/d9/IJPVM-14-88.PMC10580195.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Relationship between Structural Features of Built Environment and Physical Activity using Geographic Information Systems (GIS).","authors":"Pardis Noormohammadpour, Ehsan Ghadimi, Amirhossein Memari, Maryam Selk-Ghaffari, Mohammad Ali Mansournia, Ramin Kordi","doi":"10.4103/ijpvm.ijpvm_285_22","DOIUrl":"10.4103/ijpvm.ijpvm_285_22","url":null,"abstract":"<p><strong>Background: </strong>Built environment determinants of engaging in physical activity are dependent on the properties of societies. This study investigates the relationship between structural variables of the environment using geographic information systems (GIS) and the level of physical activity in 22 districts of Tehran.</p><p><strong>Methods: </strong>This cross-sectional study was based on Urban Health Equity Assessment and Response Tool (Urban HEART-2). Physical activity level was assessed via the Global Physical Activity Questionnaire (GPAQ). The characteristics of the neighborhood environment, including land use, street pattern, population density, and traffic, were determined via ArcGIS software. Walkability index (population density, street pattern, land use) was calculated to assess the effect of the main variables of living environment on physical activity level.</p><p><strong>Results: </strong>Among the built environmental variables, land use was associated with the total physical activity and travel-related physical activity level (r: 0.155, <i>P</i> value: 0.001, and r: 0.122, <i>P</i> value: 0.007, respectively). The walkability index indicated an association with the total physical activity level and travel-related physical activity level (r: 0.126, <i>P</i> value: 0.006, and r: 0.135, <i>P</i> value: 0.001, respectively). Higher levels of the walkability index were associated with an improved level of physical activity (OR: 2.04).</p><p><strong>Conclusions: </strong>Walkability index and land use positively correlate with total physical activity level, and providing action plans that improve walkability index and land use might lead to increased physical activity level.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"89"},"PeriodicalIF":2.1,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/87/IJPVM-14-89.PMC10580202.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Overcorrecting Minus Lens Therapy in Intermittent Exotropia for Prevention of Constant Exotropia in Children Under the Age of 7 Years.","authors":"Yousef Alizadeh, Abdolreza Medghalchi, Soheil Soltanipour, Mohammad J Mohammadi, Reza Soltani-Moghadam, Hassan Behboudi, Ebrahim Azaripour, Altinai Soleimani","doi":"10.4103/ijpvm.ijpvm_130_22","DOIUrl":"10.4103/ijpvm.ijpvm_130_22","url":null,"abstract":"<p><strong>Background: </strong>The basis of the overcorrecting minus lens is to induce compliance and consequently prevent constant exotropia. Some previous studies advocated early surgical therapy and others suggested over-minus treatment. Our purpose is to evaluate the success rate of the over-minus lens.</p><p><strong>Methods: </strong>This descriptive cross-sectional study was carried out on 106 patients under the age of 7 years with intermittent exotropia (IXT) who attended Amir-Al-Momenin Hospital at Guilan University of Medical Sciences, Iran. The data was gathered by a form including sex, age, level of cycloplegic refraction, the amount of deviation before and after using the over-minus glasses, visual acuity, the amount of the over-minus glasses, duration of treatment, recovery, and follow-up. The success rate was defined as decreasing exotropia to less than ten prism diopters or exophoria.</p><p><strong>Results: </strong>A total of 106 patients with a mean age of 2.25 ± 0.74 years were enrolled in this study. The mean exotropia before and after treatment was 20.96 ± 8.20 and 12.16 ± 11.04 prism diopters, respectively, and there was a statistically significant difference (<i>P</i> < 0.002). The mean refractive spherical and astigmatic errors (cycloplegic refraction) were +1.34 ± 1.07 and -0.32 ± 0.72 diopters, respectively. At the end of the follow-up, exotropia increased in 5.6% of patients, there was no change in 15% of patients with a mean deviation of 25.0 ± 6.06 prism diopters, and 79.24% of patients were treated successfully.</p><p><strong>Conclusions: </strong>According to the results of this study, treatment of IXT by over-correcting lenses can be a safe procedure and effective in preventing exotropia.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"80"},"PeriodicalIF":1.7,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/18/IJPVM-14-80.PMC10580209.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Patterns in 1125 Iranian Women: Adequacy of Energy and Micronutrient Intakes and Weight Statuses.","authors":"Marjan Ajami,&nbsp;Forouzan Salehi,&nbsp;Naser Kalantari,&nbsp;Mohsen Asadilari,&nbsp;Farnaz Roshanmehr,&nbsp;Anahita Houshiarrad,&nbsp;Mina Esmaeili,&nbsp;Morteza Abdollahi","doi":"10.4103/ijpvm.ijpvm_133_21","DOIUrl":"https://doi.org/10.4103/ijpvm.ijpvm_133_21","url":null,"abstract":"<p><strong>Background: </strong>Women's nutrition status includes significant effects on their children and household health. The purpose of this study was to assess energy and micronutrient intake adequacy in Iranian women.</p><p><strong>Methods: </strong>This study was a part of the Urban HEART Study, which has jointly been developed by the World Health Organization (WHO) Centre for Health Development, Kobe, Japan. In total, anthropometric and dietary intake data were collected from 1125 women in southern Tehran municipality districts. A 24-h recall questionnaire was completed by the expert nutritionists and the participants' anthropometric statuses were assessed. Food intakes were calculated in grams per capita per day. Micronutrients and energy requirements were adapted from WHO/Food and Agriculture Organization (FAO) tables and Iran National Food Consumption Survey, respectively.</p><p><strong>Results: </strong>Nearly 71.5% of the women were overweight or obese [body mass index (BMI) ≥25 kg/m²]. Furthermore, 1.2% of the women were underweight (BMI <18.5 kg/m²), while 27.3% had normal weight (BMI = 18.5--24.9 kg/m²). The mean bread/cereal and vegetable intakes were significantly higher in obese group, compared to that in normal/under/overweight group (375.6 g/day ± 151.4, <i>P</i> = 0.05; and 331.4 g/day ± 227.5, <i>P</i> = 0.02), respectively]. Women in the lean group significantly consumed higher quantities of cakes/pastries and had the lowest calcium and iron adequacy ratios, compared to other groups (<i>p</i> = 0.001, <i>P</i> = 0.03, and <i>P</i> = 0.05, respectively).</p><p><strong>Conclusions: </strong>These findings suggest that Iranian women, especially those who reside in the southern areas of Tehran, need to change their dietary habits to maintain their health. Moreover, being under/normal weight does not necessarily mean following healthy diets.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"82"},"PeriodicalIF":2.1,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/47/14/IJPVM-14-82.PMC10580216.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Vitamins and Minerals Supplementation on COVID-19 Prevention: Benefit or Risk?","authors":"Erika Aparecida Silveira,&nbsp;Patricia Constante Jaime,&nbsp;Matias Noll,&nbsp;Cesar de Oliveira","doi":"10.4103/ijpvm.ijpvm_138_21","DOIUrl":"https://doi.org/10.4103/ijpvm.ijpvm_138_21","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"14 ","pages":"84"},"PeriodicalIF":2.1,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6a/05/IJPVM-14-84.PMC10580208.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}