Rafat Shadmehr, Mehdi Sharafi, Mohammadhossien Shahabzadeh, Mostafa Bijani, Rahim Sharafkhani, Babak Pezeshki, Abdolmajid Ghasemian, Azizallah Dehghan
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引用次数: 0
摘要
背景:本研究旨在确定Fasa波斯队列数据中鸦片使用与代谢综合征之间的关系。方法:这是一项在Fasa波斯队列研究第一阶段的参与者中进行的分析性横断面研究。共有10074名参与者(年龄在35-70岁之间)被研究。MetS是根据国家胆固醇教育计划ATP III (NCEP-ATP III)标准定义的。单因素分析采用独立样本t检验和卡方检验,多因素logistic回归控制潜在混杂因素,计算优势比(or)。结果:met在整个人群中的患病率为24.6%(女性28.42% vs男性19.94%,P < 0.001)。鸦片使用率为23.2%。吸烟者发生代谢综合征的几率低于不吸烟者(OR = 1.17%, 95% CI 1.001-1.37)。结论:本研究结果表明,鸦片消费与代谢综合征呈反比关系。然而,这项研究是横断面的,需要纵向研究来获得更准确的结论。鸦片也是一种致癌物。因此,不建议使用。
Associations of Opium Use with Metabolic Syndrome in Fasa PERSIAN Cohort Study: A Population-Based Study.
Background: This study aimed to determine the relationships between opium use and metabolic syndrome in Fasa PERSIAN cohort data.
Methods: This was an analytical cross-sectional study conducted among participants of the first phase of the Fasa PERSIAN cohort study. A total of 10,074 participants (aged 35-70 years) were studied. The MetS was defined as per the National Cholesterol Education Program ATP III (NCEP-ATP III) criteria. Independent sample t-test and Chi-square test were used for univariate analysis, and multivariate logistic regression was used to control for potential confounders and calculate odds ratios (ORs).
Results: The MetS prevalence was 24.6% in the whole population (28.42% in women vs. 19.94% in men, P < 0.001). The prevalence of opium use was 23.2%. The odds of metabolic syndrome in smokers was lower than in non-smokers (OR = 1.17%, 95% CI 1.001-1.37).
Conclusions: The results of this study showed that opium consumption has an inverse relationship with metabolic syndrome. However, this study was cross-sectional, and longitudinal studies are needed for more accurate conclusions. Opium is also a carcinogen. Therefore, its use is not recommended.
期刊介绍:
International Journal of Preventive Medicine, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online journal with Continuous print on demand compilation of issues published. The journal’s full text is available online at http://www.ijpvmjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal will cover technical and clinical studies related to health, ethical and social issues in field of Preventive Medicine. Articles with clinical interest and implications will be given preference.