Raheleh Karimi, Mina Norozirad, Foad Esmaeili, Marjan Mansourian, Hamid R Marateb
{"title":"COVID-19 Vaccination and Cardiovascular Events: A Systematic Review and Bayesian Multivariate Meta-Analysis of Preventive Benefits and Risks.","authors":"Raheleh Karimi, Mina Norozirad, Foad Esmaeili, Marjan Mansourian, Hamid R Marateb","doi":"10.4103/ijpvm.ijpvm_260_24","DOIUrl":"10.4103/ijpvm.ijpvm_260_24","url":null,"abstract":"<p><strong>Background: </strong>To provide a detailed understanding and apply a comprehensive strategy, this study examines the association between COVID-19 vaccination and cardiovascular events. We conducted a Bayesian multivariate meta-analysis using summary data across multiple outcomes including myocardial infarction, stroke, arrhythmia, and CAD, considering potential dependencies in the data. Markov chain Monte Carlo (MCMC) methods were detected for easy implementation of the Bayesian approach. Also, the sensitivity analysis of the model was done by using different priors.</p><p><strong>Methods: </strong>Fifteen studies were included in the systematic review, with eleven studies comparing the results between the vaccine group and the unvaccinated group. Additionally, six studies were used for further analysis to compare mRNA COVID-19 Vaccines (Pfizer-BioNTech and Moderna).</p><p><strong>Results: </strong>Bayesian meta-analysis revealed a link between vaccines and CAD risk (OR, 1.70; 95% CrI: 1.11-2.57), particularly after BNT162b2 (OR, 1.64; 95% CrI: 1.06-2.55) and second dose (OR, 3.44; 95% CrI: 1.99-5.98). No increased risk of heart attack, arrhythmia, or stroke was observed post-COVID-19 vaccination. As the only noteworthy point, a protective effect on stroke (OR, 0.19; 95% CrI: 0.10-0.39) and myocardial infarction (OR, 0.003; 95% CrI: 0.001-0.006) was observed after the third dose of the vaccine.</p><p><strong>Conclusions: </strong>Secondary analysis showed no notable disparity in cardiovascular outcomes between BNT162b2 and mRNA vaccines. The association of COVID-19 vaccination with the risk of coronary artery disease should be considered in future vaccine technologies for the next pandemic.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"14"},"PeriodicalIF":1.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Prognostic Yield of Admission Shock Index in Patients with ST-Segment Elevation Myocardial Infarction: SEMI-CI Study.","authors":"Shaghayegh Ferdowsain, Davood Shafie, Azam Soleimani, Maryam Heidarpour, Hamidreza Roohafza, Fatemeh Nouri, Mehrbod Vakhshoori, Masoumeh Sadeghi","doi":"10.4103/ijpvm.ijpvm_43_24","DOIUrl":"10.4103/ijpvm.ijpvm_43_24","url":null,"abstract":"<p><strong>Background: </strong>Early identification of high-risk patients presenting with ST-segment elevation myocardial infarction (STEMI) helps prevent complications. The shock index (SI) is a bedside risk-stratification tool used in emergency departments. In this study, we aimed to assess the SI's predictive value for prognosticating in-hospital and one-year mortality, as well as one-year major cardiovascular events (MACEs). As secondary endpoints, we assessed the age SI's performance and the influence of prehospital transport factors on SI's predictive value.</p><p><strong>Methods: </strong>This prospective cohort study is named SEMI-CI and enrolled patients with STEMI who were referred to a cardiology hospital in Isfahan. We analyzed data on 867 patients with STEMI. Systolic blood pressure (SBP) and heart rate (HR) upon admission were used to calculate SI. Patients were divided into two groups based on SI, and 277 patients had SI > 0.7.</p><p><strong>Results: </strong>In-hospital death, one-year mortality, and MACE were more prevalent in those patients presenting with SI ≥ 0.7. However, after multivariate adjustment, SI was an independent predictor of in-hospital mortality and MACE, but it was not associated with one-year mortality. Furthermore, mortality rates increased from lower to higher age groups. Among patients transferred by emergency medical services to our hospital, SI showed prognostic implications for in-hospital mortality but not for one-year mortality.</p><p><strong>Conclusions: </strong>The current study showed that a positive SI and age SI are valuable risk-stratification tools to identify high-risk patients presenting with STEMI.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"15"},"PeriodicalIF":1.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MusQan Initiative: Challenges and Opportunities.","authors":"Ram K Garg","doi":"10.4103/ijpvm.ijpvm_194_24","DOIUrl":"10.4103/ijpvm.ijpvm_194_24","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"11"},"PeriodicalIF":1.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relation Between Smoking and Disability Progression in Iranian Multiple Sclerosis Patients: A Case-Control Study.","authors":"Fereshteh Ashtari, Mahtab Sardashti Birjandi, Iman Adibi, Awat Feizi, Arshia Ghalamkari, Nafiseh Toghianifar","doi":"10.4103/ijpvm.ijpvm_336_23","DOIUrl":"10.4103/ijpvm.ijpvm_336_23","url":null,"abstract":"<p><strong>Background: </strong>To compare characteristics of patients with multiple sclerosis (MS) between cigarette smokers and non-smokers.</p><p><strong>Methods: </strong>A case-control study was performed on patients registered in the Kashani MS center from April 2019 to April 2020 in Isfahan, Iran. In total, 136 smoker patients and 220 non-smokers participated in the study and completed the questionnaire.</p><p><strong>Results: </strong>The frequency of male gender in the smoker group was significantly higher than in the non-smokers (64.7% vs. 15%, <i>P</i> < 0.001). The mean age at MS onset was 31.5 ± 9.60 years among cigarette smokers and 29.7 ± 9.47 years among non-smokers (<i>P</i> = 0.794). Furthermore, 80% of cigarette smokers and 64% of non-smokers had at least one relapse per year (ARR ≥1, <i>P</i> < 0.001). The Expanded Disability Status Scale (EDSS) of more than 4.5 was significantly higher in smokers (26.5% vs. 18%, <i>P</i> = 0.023). There was a relation between an EDSS of more than 4.5 and an interval between smoking initiation and disease onset (<i>P</i> = 0.004). Long duration of smoking was associated with a higher disability scale (16.4 ± 9.5 vs. 9.8 ± 7.3, <i>P</i> = 0.008). Men smoked for a longer period of time before developing MS than women (9.24 ± 10.07 vs. 4.47 ± 7.61, <i>P</i> = 0.002). The average daily cigarette consumption was 7.74 ± 6.65 in women and 10.84 ± 9.44 in men (<i>P</i> = 0.024). Duration of smoking before the onset of the disease was 4.47 ± 7.61 years in women and 9.24 ± 10.07 in men (<i>P</i> = 0.002).</p><p><strong>Conclusions: </strong>Our data suggest that there is a possible relationship between disability score and the duration of smoking before the onset of MS. It also revealed that the duration of smoking can affect the progression of the disease. Further studies are suggested to confirm these findings.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"12"},"PeriodicalIF":1.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masoud Etemadifar, Nahad Sedaghat, Hussien Sbeity, Hasan Kaveyee
{"title":"Prevalence of Stroke in People with Multiple Sclerosis.","authors":"Masoud Etemadifar, Nahad Sedaghat, Hussien Sbeity, Hasan Kaveyee","doi":"10.4103/ijpvm.ijpvm_153_24","DOIUrl":"10.4103/ijpvm.ijpvm_153_24","url":null,"abstract":"","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"10"},"PeriodicalIF":1.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michail Tsanasidis, Theodora Kafkia, Dimitrios Papoutsis, Michael Kourakos
{"title":"Resilience, Pain Self-efficacy and Health-related Quality of Life in Greek Hemodialysis Patients: A Cross-sectional Study.","authors":"Michail Tsanasidis, Theodora Kafkia, Dimitrios Papoutsis, Michael Kourakos","doi":"10.4103/ijpvm.ijpvm_108_24","DOIUrl":"10.4103/ijpvm.ijpvm_108_24","url":null,"abstract":"<p><strong>Background: </strong>Regardless of the recent advances in Chronic Kidney Disease stage 5 (CKD-5) management people on dialysis face significant changes in their quality of life. The present study aimed to examine the relationship between psychological resilience and quality of life in patients undergoing in-center hemodialysis.</p><p><strong>Methods: </strong>An initial sample of 150 adult patients on hemodialysis for more than 6 months was selected from hospitals in a Southern European country. The study used the Connor-Davidson Resilience Scale (CD-RISC), the Pain Self-Efficacy Questionnaire (PSEQ), and the Kidney Disease Quality of Life (KDQOL-36) questionnaires to assess levels of psychological resilience, pain self-efficacy and quality of life.</p><p><strong>Results: </strong>The results indicated that higher levels of psychological resilience were associated with higher levels of pain self-efficacy, which in turn led to better quality of life.</p><p><strong>Conclusions: </strong>The findings suggest that psychological resilience and pain self-efficacy play important roles in the health-related quality of life of people on hemodialysis, regardless of demographic factors such as age and gender. These have implications for practice in CKD-5 management and highlight the importance of addressing psychological factors in dialysis care.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"9"},"PeriodicalIF":1.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Hassan Olamazadeh, Fahimeh Esfarjani, Sayed Mohammad Marandi, Saeed Zamani, Fahimeh Zamani Rarani, Mohammadreza Sharifi
{"title":"The Heart Tissue Molecular Response to Resistance Training in Comparison to Irisin Injection: A Focus on VEGF Gene/Protein Expression and Correlations with Serum Irisin Levels.","authors":"Mohammad Hassan Olamazadeh, Fahimeh Esfarjani, Sayed Mohammad Marandi, Saeed Zamani, Fahimeh Zamani Rarani, Mohammadreza Sharifi","doi":"10.4103/ijpvm.ijpvm_79_24","DOIUrl":"10.4103/ijpvm.ijpvm_79_24","url":null,"abstract":"<p><strong>Background: </strong>Angiogenesis is crucial in the recovery and maintenance of heart function. Irisin may mediate the cardiac health-promoting impact of exercise training. The aim of this study was to comparatively assess VEGF gene/protein expression in the heart tissue and correlations with serum irisin levels following resistance training, in comparison to exogenous irisin injection.</p><p><strong>Methods: </strong>Twenty-one <i>NMRI</i> mice were randomly assigned to the three group (<i>n</i> = 7 for each group): control, resistance exercise, and irisin. Exercised mice, for 8 weeks, three sessions per week and four sets of five repeats for each session were considered and mice climbed up a 1-m-height ladder with a slope of 80 degrees with a weight equal to 30% of mouse's body weight fastened to their tails and gradually increased up twofold of body weight. The Irisin group received 100 μg/kg/week irisin for 8 weeks, intraperitoneally. The cardiac expression of the <i>VEGF</i> gene, by real-time PCR, the level of VEGF protein, by IHC (immunohistochemistry) and western blot analysis, and serum irisin concentration, by ELISA, were evaluated.</p><p><strong>Results: </strong>The expression of the VEGF gene and protein, as well as serum Irisin levels, increased in all experimental mice compared to the control group (<i>P</i> < 0.05). Pearson's correlation coefficient data indicated a positive correlation between the analyzed parameters in each group (<i>P</i> < 0.05 and <i>r</i> > 0).</p><p><strong>Conclusions: </strong>There appears to be an interaction between resistance exercise and cardiac angiogenesis factors, mediated by irisin. So, irisin could be considered in cardiovascular health interventions, aiming to target specific molecules or pathways.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"13"},"PeriodicalIF":1.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saeed Saeedbakhsh, Maryam Mohammadi, Sarina Younesi, Mohammad Sattari
{"title":"Using Internet of Things for Child Care: A Systematic Review.","authors":"Saeed Saeedbakhsh, Maryam Mohammadi, Sarina Younesi, Mohammad Sattari","doi":"10.4103/ijpvm.ijpvm_191_23","DOIUrl":"10.4103/ijpvm.ijpvm_191_23","url":null,"abstract":"<p><strong>Background: </strong>In smart cities, prioritizing child safety through affordable technology like the Internet of Things (IoT) is crucial for parents. This study seeks to investigate different IoT tools that can prevent and address accidents involving children. The goal is to alleviate the emotional and financial toll of such incidents due to their high mortality rates.</p><p><strong>Methods: </strong>This study considers articles published in English that use IoT for children's healthcare. PubMed, Science Direct, and Web of Science databases are considered as searchable databases. 273 studies were retrieved after the initial search. After eliminating duplicate records, studies were assessed based on input and output criteria. Titles and abstracts were reviewed for relevance. Articles not meeting criteria were excluded. Finally, 29 cases had the necessary criteria to enter this study.</p><p><strong>Results: </strong>The study reveals that India is at the forefront of IoT research for children, followed by Italy and China. Studies mainly occur indoors, utilizing wearable sensors like heart rate, motion, and tracking sensors. Biosignal sensors and technologies such as Zigbee and image recognition are commonly used for data collection and analysis. Diverse approaches, including cloud computing and machine vision, are applied in this innovative field.</p><p><strong>Conclusions: </strong>In conclusion, IoT for children is mainly seen in developed countries like India, Italy, and China. Studies focus on indoor use, using wearable sensors for heart rate monitoring. Biosignal sensors and various technologies like Zigbee, Kinect, image recognition, RFID, and robots contribute to enhancing children's well-being.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"3"},"PeriodicalIF":1.7,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic Value of Mean Platelet Volume, Neutrophil-to-Lymphocyte Ratio, and Platelet to Lymphocyte Ratio for Late-Onset Neonatal Sepsis.","authors":"Behzad Barekatain, Elahe Mardani, Alireza Sadeghnia, Zahra Heidari","doi":"10.4103/ijpvm.ijpvm_45_23","DOIUrl":"10.4103/ijpvm.ijpvm_45_23","url":null,"abstract":"<p><strong>Background: </strong>Neonatal sepsis (NS) is the most common cause of neonatal mortality, currently confirmed with blood culture as the diagnostic gold standard. However, being time-consuming, false-negative results, being affected by even a single dose of antibiotics, and expensiveness are negative aspects. Therefore, we aimed to investigate the diagnostic value of complete blood count (CBC) parameters: mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR) which have been suggested in previous studies.</p><p><strong>Methods: </strong>A total of 100 term and preterm neonates (age ≥ 32 weeks) hospitalized in Alzahra and Shahid Beheshti hospitals in Isfahan, Iran, were studied. Fifty neonates with late neonatal sepsis were placed in the case group, and 50 neonates with other diagnoses were placed in the control group. Neonatal blood samples were sent to the laboratory, and MPV, NLR, and PLR were measured.</p><p><strong>Results: </strong>The mean (standard deviation) of MPV was 7.20 (4.39) in the case group and 9.55 (0.87) in the control group, and there was a significant difference between them (<i>P</i> value = 0.001). At the cutoff point of 8.25 in MPV, the area under the curve (AUC) was 0.594 with a sensitivity of 100% and specificity of 30%. The mean (standard deviation) of NLR was 1.79 (1.21) in the case group and 2.28 (1.25) in the control group, and there was no significant difference between them (<i>P</i> value = 0.692). The mean (standard deviation) of PLR was 62.58 (34.57) in the case group and 65.11 (28.55) in the control group, and there was no significant difference between them (<i>P</i> value = 0.836).</p><p><strong>Conclusions: </strong>MPV, unlike NLR and PLR, can be used as a sensitive and cost-effective primary screening index in late NS at the cutoff point of 8.25 due. However, low specificity suggests a poor diagnostic value.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"1"},"PeriodicalIF":1.7,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafat Shadmehr, Mehdi Sharafi, Mohammadhossien Shahabzadeh, Mostafa Bijani, Rahim Sharafkhani, Babak Pezeshki, Abdolmajid Ghasemian, Azizallah Dehghan
{"title":"Associations of Opium Use with Metabolic Syndrome in Fasa PERSIAN Cohort Study: A Population-Based Study.","authors":"Rafat Shadmehr, Mehdi Sharafi, Mohammadhossien Shahabzadeh, Mostafa Bijani, Rahim Sharafkhani, Babak Pezeshki, Abdolmajid Ghasemian, Azizallah Dehghan","doi":"10.4103/ijpvm.ijpvm_164_23","DOIUrl":"10.4103/ijpvm.ijpvm_164_23","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to determine the relationships between opium use and metabolic syndrome in Fasa PERSIAN cohort data.</p><p><strong>Methods: </strong>This was an analytical cross-sectional study conducted among participants of the first phase of the Fasa PERSIAN cohort study. A total of 10,074 participants (aged 35-70 years) were studied. The MetS was defined as per the National Cholesterol Education Program ATP III (NCEP-ATP III) criteria. Independent sample <i>t</i>-test and Chi-square test were used for univariate analysis, and multivariate logistic regression was used to control for potential confounders and calculate odds ratios (ORs).</p><p><strong>Results: </strong>The MetS prevalence was 24.6% in the whole population (28.42% in women vs. 19.94% in men, <i>P</i> < 0.001). The prevalence of opium use was 23.2%. The odds of metabolic syndrome in smokers was lower than in non-smokers (OR = 1.17%, 95% CI 1.001-1.37).</p><p><strong>Conclusions: </strong>The results of this study showed that opium consumption has an inverse relationship with metabolic syndrome. However, this study was cross-sectional, and longitudinal studies are needed for more accurate conclusions. Opium is also a carcinogen. Therefore, its use is not recommended.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"4"},"PeriodicalIF":1.7,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}