International Journal of Pharmacy & Integrated Health Sciences最新文献_第4页

PRACTICE, ATTITUDE AND KNOWLEDGE OF CONTACT LENSE USERS AMONG LAHORE POPULATION 拉合尔人群中隐形眼镜使用者的行为、态度和知识

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2022-03-25 DOI: 10.56536/ijpihs.v3i1.23

引用次数: 0

YOGHURT: PROCESSING TECHNOLOGY AND NUTRITIONAL PROFILE 酸奶:加工工艺及营养成分

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2022-03-25 DOI: 10.56536/ijpihs.v3i1.22

Muhammad Anees Ur Rehman, Khurram Ashfaq, Faiza Iqbal, Idress Khan, Amna Azar

引用次数: 1

T CELL AGING IN RHEUMATOID ARTHRITIS 类风湿关节炎中的T细胞老化

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2022-03-25 DOI: 10.56536/ijpihs.v3i1.24

Maria Oubaid, BushraTahreem, Toba Samreen, Javeria Parveen, Idrees Khan

{"title":"T CELL AGING IN RHEUMATOID ARTHRITIS","authors":"Maria Oubaid, BushraTahreem, Toba Samreen, Javeria Parveen, Idrees Khan","doi":"10.56536/ijpihs.v3i1.24","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i1.24","url":null,"abstract":"With the progression of aging, the immune system and the tendency for abnormal immunological changes are common. Individuals over the age of 50 years are susceptible to infectious diseases as well as inflammation and immune-mediated tissue damage. Aging is the main cause of disease pathology and death, continuously enhancing the risk of cardiovascular disease, malignancy, and infectious diseases. One of the important causes is higher susceptibility to autoimmune diseases like rheumatoid arthritis and other immunodeficiency syndromes. Inflammation is common in age-related pathologies. In immune cells, T lymphocytes have an extensive life cycle and show a robust copying force, constructing them sensitive to ageing-associated pathologies. In dysfunctional ageing of T-cells, protection of T-cell function and cells capable of promoting inflammation are abundant. Rheumatoid arthritis is a long-lasting autoimmune disease that mainly affects the joints. Though RA develops at an early age, the frequency of developing RA increases with the increase in age. It is also seen that RA may develop as a result of premature ageing (immunosenescence) of the immune system. In RA, T-cell ageing occurs prematurely, but the mechanism involved and their role in tissue damage is still uncertain. T-cell ageing and its effects on rheumatoid arthritis are discussed here, as well as how T-cells participate in tissue damage, acute and chronic inflammation, and the ageing process. Also review the DNA damage in response to T-cell aging, telomeric ends shortening during RA and immunosenescence, and Tcells in RA.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"162 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129000450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

RATIONAL USE OF 3rd GENERATION CEPHALOSPORINS IN TERTIARY CARE HOSPITALS: A CONCURRENT DUR 第三代头孢菌素在三级医院的合理使用:并发时间

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2022-03-25 DOI: 10.56536/ijpihs.v3i1.21

{"title":"RATIONAL USE OF 3rd GENERATION CEPHALOSPORINS IN TERTIARY CARE HOSPITALS: A CONCURRENT DUR","authors":"","doi":"10.56536/ijpihs.v3i1.21","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i1.21","url":null,"abstract":"Background: Assessment of use of antimicrobials can be performed by evaluating their use. Drug use evaluation is a performance improvement method that concentrates on improvement and evaluation of drug use processes to achieve optimal patient outcomes. \u0000Objective: The objective of this study was the evaluation of 3rd generation cephalosporins in tertiary care hospitals of Lahore. \u0000Method: A concurrent cross-sectional study was conducted on 160 patient files selected using systematic random sampling method from in-patient prescriptions with 3rd generation cephalosporin during hospitalization in tertiary care hospitals. Descriptive statistics were applied by using IBM SPSS statistics version 28. Results: Out of the 200 patient file, 160 patient files have complete information of the prescribed drug. Among the 160 patients, 67(41%) were female and 93(58.1%) males. Among 160 patients, 141(88.1%) Ceftriaxone was most commonly prescribed drug followed by 14(8.8%) Cefoperazone (in combination with salbactam) the 5(3.1%) were given cefixime and in indications for drug being prescribed 103(64.5%) were found to be appropriate while 57(35.5%) were inappropriate. (Not according to the WHO criteria for prescribing the third-generation cephalosporin). \u0000Conclusions: To improve the rational use of 3 rd generation cephalosporins and prevent the development of resistance; prescribers should adhere to the national standard treatment guideline.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132169358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prosopis cineraria Druce (Jand) – A Review of its Ethnomedicinal, Phytochemical and Pharmacological Properties 棘豆的民族药、植物化学和药理研究进展

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2021-12-31 DOI: 10.56536/ijpihs.v2i1.13

{"title":"Prosopis cineraria Druce (Jand) – A Review of its Ethnomedicinal, Phytochemical and Pharmacological Properties","authors":"","doi":"10.56536/ijpihs.v2i1.13","DOIUrl":"https://doi.org/10.56536/ijpihs.v2i1.13","url":null,"abstract":"The use of medicinal plants and validation of their pharmacological properties have exponentially increased since last century. Selection of solvents for making plant extracts that yield significant results has also been a subject of discussion. Prosopis cineraria commonly called Jand, Khejri, Khej has great medicinal importance due to its broad range of phytochemistry and pharmacological properties. It is native to Pakistan, India, Oman, Afghanistan and few European countries. Many different parts of this plant are used traditionally for the treatment of numerous mild to serious diseases. Stem bark, root, seeds, leaves and flowers are predominantly used for the effective treatment of multiple ailments with a range of pharmacological actions involving gastrointestinal, metabolic, spasmolytic, anti-oxidant, antitumor, anti-convulsant, anthelmintic, anti-microbial, analgesic, anti- pyretic, bronchodilator, and anti-lipidemic properties. The present review highlights only the methanolic extract of this plant that has more validated pharmacological properties as compared to ethanolic, aqueous, chloroform and petroleum ether extract.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"1640 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123374802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

KNOWLEDGE, ATTITUDE AND PRACTICE AMONG HEALTHCARE PROFESSIONALS TOWARDS ADR REPORTING IN ABBOTTABAD PAKISTAN 巴基斯坦阿伯塔巴德保健专业人员对药品不良反应报告的知识、态度和做法

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2021-12-31 DOI: 10.56536/ijpihs.v2i1.16

Deeba Bashir, Mehreen Khan Jadoon, Sadaf Imtiaz Abbasi, Saman Kaleem, Shumaila Bibi, Muhammad Junaid, Hassan Sharif

{"title":"KNOWLEDGE, ATTITUDE AND PRACTICE AMONG HEALTHCARE PROFESSIONALS TOWARDS ADR REPORTING IN ABBOTTABAD PAKISTAN","authors":"Deeba Bashir, Mehreen Khan Jadoon, Sadaf Imtiaz Abbasi, Saman Kaleem, Shumaila Bibi, Muhammad Junaid, Hassan Sharif","doi":"10.56536/ijpihs.v2i1.16","DOIUrl":"https://doi.org/10.56536/ijpihs.v2i1.16","url":null,"abstract":"Background: Healthcare professionals can play an important role in reporting adverse drug reactions as it is a global health problem and required to be addressed. \u0000Objectives: This study’s objective was to assess the knowledge, barriers and encouraging factors for healthcare professionals towards ADR reportage. \u0000Methodology: Prospective cross-sectional survey was conducted. Using spss 16 (statistical package for social sciences) data was analyzed. \u0000Results: The questionnaires were distributed to 125 participants. ADR reporting form is very essential for the reporting of ADRs. Unfortunately in our healthcare setups, no such reporting forms are available because of lack of ADR reporting system. Healthcare system members should be held responsible for the reporting of ADRs as 43.2% believe they have an obligation to do so. \u0000Conclusion: The inadequacies in the act of ADR reportage could not be really settled provided that the prescribers are approachable of the significance of revealing. Enlarging the reportage base by extending it to medical caretakers, drug specialists, and other medical care experts would likewise assist.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131827469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge and Practices of contraceptives in married women population; A cross sectional survey from Lahore, Pakistan 已婚妇女避孕知识和做法的调查巴基斯坦拉合尔的横断面调查

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2021-12-31 DOI: 10.56536/ijpihs.v2i1.12

{"title":"Knowledge and Practices of contraceptives in married women population; A cross sectional survey from Lahore, Pakistan","authors":"","doi":"10.56536/ijpihs.v2i1.12","DOIUrl":"https://doi.org/10.56536/ijpihs.v2i1.12","url":null,"abstract":"Background: About one third of all pregnancies are unplanned and 20% of all pregnancies end n abortion and to cope with this problem nearly all general practitioners provide contraceptive advice. Objectives: A cross sectional study was conducted in the OPD of Gynae and Obstreitics unit of Shama hospital, Government hospital Kot Khawaja Saeed, Ganga Ram , Rasheed latifand Farooq hospital from December 2017-March 2018 to determine the knowledge and practice of contraceptive utilization in married women of Lahore. \u0000Method: This study was carried out among 308 married women between the ages 17-50 years by administering a well-developed and validated questionnaire. Data was analyzed by using SPSS version 16. \u0000Results: Study results showed about 85% of participants have knowledge about contraceptives and 19.1% were aware about the ADR’S of contraceptives. The main source of information identified was health care providers (62.2%) and television (37.4%). The most commonly used contraceptives were oral contraceptive pills 36.1%, followed by condoms, injectable, IUD’s and barrier method. Known uses of contraceptives were 41.5% and the major reason for known use were prohibition by religion (23.8%) followed by lack of knowledge, economic problems and other reasons such as opposed by family members. \u0000Conclusion: The study shows low use of contraceptives despite high level of awareness. It highlights the need to motivate people for effective and appropriate use of contraceptives and to avoid the unwanted pregnancies and abortions.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"229 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134515735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation and Optimization of Aceclofenac Loaded Nanosuspension 载乙酰氯芬酸纳米混悬液的制备及优化

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2021-12-31 DOI: 10.56536/ijpihs.v2i1.15

{"title":"Formulation and Optimization of Aceclofenac Loaded Nanosuspension","authors":"","doi":"10.56536/ijpihs.v2i1.15","DOIUrl":"https://doi.org/10.56536/ijpihs.v2i1.15","url":null,"abstract":"Background: The aceclofenac sodium is used as non-steroidal anti inflammatory drug (NSAID), administered through the oral route, causing numerous side effects like nausea, vomiting, dyspepsia, gastrointestinal bleeding and peptic ulcer. NSAIDs, promote the secretions of hydrochloric acid which cause severe damage to the walls of gastro intestinal tracts well as to the drug. \u0000Objectives: Aceclofenac was added in combination with different polymers to form a uniform nano suspension. \u0000Methodology: Three sets of formulations were prepared by using silverson mixer. The organoleptic evaluation, particle size determination, assay, in vitro drug release study and drug excipient compatibility studies were performed. The results were obtained on the basis of drug and excipients compatibility studies, scanning electron microscopy, In vitro drug release study and assay studies. \u0000Results: In this study, the nanosuspension of aceclofenac sodium is produced, which spread on the wider surface area of GIT. Due to this reason, the decrease in accumulated concentration, the secretion of hydrochloric acid is not promoted, the chance of damage to GIT is drastically reduced, and the drug also escaped from the damage and the absorption of drug is also increased. \u0000Conclusion: The F1 formulation showed best results as compared to other two formulations. These results were obtained due to the effect of polymers used in combination with drug and surfactant.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133940054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Functionality of P&TC and Availability of Hospital Formulary in various Hospitals of Lahore, Pakistan 巴基斯坦拉合尔各医院产销控制系统功能及医院处方集可得性评价

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2021-12-31 DOI: 10.56536/ijpihs.v2i1.17

{"title":"Evaluation of Functionality of P&TC and Availability of Hospital Formulary in various Hospitals of Lahore, Pakistan","authors":"","doi":"10.56536/ijpihs.v2i1.17","DOIUrl":"https://doi.org/10.56536/ijpihs.v2i1.17","url":null,"abstract":"Objectives: To evaluate the functionality of P&TC and availability of hospital formulary in different hospitals of Lahore, Pakistan. \u0000Methodology: This study was conducted in 19 hospitals (public/private-secondary and tertiary care) of Lahore, by a designed Questionnaire Performa regarding the availability and functionality of hospital formulary. Data was entered in Excel sheet and analyzed for statistical analysis. \u0000Results: During our studies, it was observed that 16(84.2%) hospitals were responsive to give information and 3(15.8%) hospitals refused to give us data. Pharmacy and therapeutics committee was present in 10(52.6%) hospitals and in 6(31.6%) hospitals there was no existence of P&TC. Hospital formulary was available in 10(52.6%) hospitals and in 2(10.5%) drug list was present and in 7(36.8%) hospitals there was neither hospital formulary nor drug list was present. In 9(47.4%) hospitals hospital formulary was in use and in 7 (36.8%) hospitals there was no usage of hospital formulary. \u0000Conclusion: It was observed during our study that P&TC seems to have an impact on quality of medicines use but very few hospitals are following the International Guidelines on the pharmacy and therapeutic Committee and theformulary system due to inadequate number of pharmacist and lack of knowledge. Strong leadership and adequate resources might deliver more effective P&TC with marked effect on health practices, thus most importantly to enhanced patient outcomes.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128330924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, attitude, perception towards COVID-19: A cross sectional study among nonprofessional population of Lahore 对COVID-19的知识、态度和看法:拉合尔非专业人群的横断面研究

International Journal of Pharmacy & Integrated Health Sciences Pub Date : 2021-12-31 DOI: 10.56536/ijpihs.v2i1.14

{"title":"Knowledge, attitude, perception towards COVID-19: A cross sectional study among nonprofessional population of Lahore","authors":"","doi":"10.56536/ijpihs.v2i1.14","DOIUrl":"https://doi.org/10.56536/ijpihs.v2i1.14","url":null,"abstract":"Background: On account of the COVID-19 pandemic, there is very different knowledge, attitude and perception among non professional population. We are cognizant that pandemic can becontrolled by providing proper knowledge and their satisfactory attitude and positive perception towards COVID-19. \u0000Objective: It is aimed to investigate the knowledge, attitude and perception regarding COVID -19 among non-professional population of Lahore. Methods: A cross sectional survey was conducted in June, 2021 by validated self – dministered questionnaire. The survey instrument was tailored from a published questionnaire comprised of questions on demographics, knowledge, attitude, perception. \u0000Results: Out of 150 random participants, 63 were employees, 43 were businessmen, 29 were daily wagers, 9 housewives. Irrespective of profession, population of Lahore has average knowledge, attitude and perception. While considering the categories we included, businessmen have better knowledge and perception while attitude is satisfactory among employees. While daily wagers showed poor knowledge, attitude and perception. Housewives also have average knowledge about this virus. \u0000Conclusion: People with greater exposure like businessmen are well aware and up-to-dated about COVID-19. Due to limited social contact housewife had not enough knowledge about COVID-19. There is need to provide equal chances to all population to get proper knowledge and awareness about this virus so that we can control it inbetter way.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"362 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134459591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

International Journal of Pharmacy &amp; Integrated Health Sciences最新文献

International Journal of Pharmacy & Integrated Health Sciences最新文献