International Journal of Pharmacy & Integrated Health Sciences最新文献

{"title":"DIETARY CONCEPTS, PATTERNS AND LIFESTYLES IN ADULTS WITH DIABETES IN PUNJAB, PAKISTAN.","authors":"Faran Khan, Dr. Anam Yasmeen, Marriam Ahmad, S. Imtiaz, Saima Bano, Sara Yasien","doi":"10.56536/ijpihs.v3i2.48","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i2.48","url":null,"abstract":"Background: It is estimated that 1.5 million fatalities were directly caused by diabetes and 2.2 million deaths were caused by high blood glucose. This study was conducted to evaluate the link of food concepts, lifestyle habits, and dietary patterns among persons with diabetes mellitus. Methodology: The participants with diabetes mellitus were chosen from the diabetic wards and OPDs of several hospitals in Punjab. There were 600 participants in the entire sample size. The questionnaire was created to evaluate diabetes-related myths about food, diabetes-related lifestyle routines, and eating habits among persons with diabetes. Statistical techniques were used percentages (%) and cross tabs. Results: The study found that 55.8% of persons have a history of diabetes mellitus in their families. A sedentary lifestyle and lack of physical activity were prevalent in about 41.8% of the population. Participants with no education or little education have higher levels of uncontrolled HbA1C than participants with some education. 24% of the individuals who lacked education thought that eating too much sugar could cause diabetes. 10% of individuals actually used a home remedy, whereas 88.8% of participants did not use any. Of the participants, 24.5% believed that home remedies were helpful in managing diabetes. Conclusion: This study shows that people do not exercise enough; about half of the participants are physically inactive. Major meals were consumed in an appropriate amount. The promotion of good eating and lifestyle practices, particularly prevention among high-risk groups, is encouraged through health education and other interventions.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"4 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120842367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANALGESIC AND ANTI-DIABETIC POTENTIAL OF ROYSTONEA REGIA","authors":"M. Munir, Muhammad Asad Saeed, Zeeshan Masood, N. Aslam, Umer Farooq, M. Farooq","doi":"10.56536/ijpihs.v3i2.47","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i2.47","url":null,"abstract":"Background: Plants are the rich source of nutrients and contain biological and pharmacological potential. Roystonea regia, a plant of Aceraceae family has been traditionally used in different countries especially in Asia. Objectives: The aim of the study was to evaluate its analgesic and anti-diabetic potential by hot plate method and Alloxan induced method in Swiss albino female rats weighing 150 to 200 gm respectively. Methodology: Shoots of Roystonea regia plant was extracted using n-hexane, chloroform and ethanol in Soxhlet apparatus. Oral acute toxicity test showed the different mortality rates of all extracts. Results: The crude n-hexane and ethanol extract showed increase in the latency time till 120 min and were found to have significant (p˂0.001) analgesic potential at 100 and 200 mg/kg dose. However, different anti-diabetic potential was shown by all three extracts. Chloroform extract showed maximum reduction in blood glucose level (BGL) and found significant (p˂0.001) as compared to negative control till 21st day at the dose of 250 and 500 mg/kg of body weight. Conclusion: Further study is required to understand the complete mechanism involved in both activities. In future, purified fractions and column chromatography can be conducted for their complete characterization and their toxic effects to establish a proper therapeutic dose for further trials.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy & Integrated Health Sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117128623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DEVELOPMENT AND SHELF STABILITY OF FUNCTIONAL DRINK PREPARED FROM WATERMELON AND CUCUMBER","authors":"Z. Batool, M. Tariq, S. W. Ali, Zujaja Umer, Mohammad Taqqi Abbas, M. Khalid","doi":"10.56536/ijpihs.v3i2.52","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i2.52","url":null,"abstract":"Background \u0000Cucumber is known to have countless benefits related to skin, body, and general health conditions. Watermelon juice is highly nutritious and perishable. Recent studies focus on using it with a combination of potential functional ingredients. Watermelon-Cucumber drink is a healthy combination of beverages that can provide many nutrients and health benefits.  \u0000Objectives \u0000In this study, cucumber juice was used to improve watermelon juice's nutritional profile and sensory attributes by utilizing honey as a sweetener. This study aimed to evaluate the functional drink's proximate parameters, oxidative stability, microbial load, and organoleptic evaluation. \u0000Methods \u0000Statistics was applied using Statistics 8.1, and data were analyzed using two-way ANOVA and Tukey HSD Post Hoc analysis. The functional drink was prepared using altering concentrations of cucumber juice and watermelon juice (80:10, 70:20, 60:30, 50:40) and stored at 4oC for 28 days. Results revealed that adding cucumber juice significantly improved antioxidant potential (p<0.05) up to 1.6%. The current study revealed that a non-significant effect was observed on ash contents (0.06-0.04%), total solids (0.36-0.32%), and degree Brix (8.7o-9.7o) of functional drink. Increasing concentration of cucumber juice led to an increase in titratable acidity (0.57%) while pH was decreased (3.6). \u0000Conclusions \u0000Using watermelon and cucumber juice in combinations improved the antioxidant potential of the functional drink. The organoleptic evaluation revealed that treatment with 80% watermelon juice and 10% cucumber juice was observed best in sensorial attributes.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy &amp; Integrated Health Sciences","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131204672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ACCESS TO MEDICINE","authors":"A. Mustafa, Anam Yasmeen","doi":"10.56536/ijpihs.v3i2.34","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i2.34","url":null,"abstract":"Availability and access to the health care facility is a fundamental right of human, it is the timely used of services according to the needs. It is included in International treaties and is recognized by authorities and various Governments throughout the world. What does it means the access to medicine? According to WHO (World Health Organization) access to medicines is “having medicines continuously available and affordable at public or private health facilities or medicine outlets that are within one hour’s walk from the homes of the population”. The affordability and availability of medicines is directly related to the strength of health care system, but the high prices of the medicines, prevalence of Non-communicable diseases (diabetes, hypertension) and increasing demand of patients are the major obstacles in this regard. According to Forbes “at least 2 billion people don’t have access to medicines  and 1 billion people live in extreme poverty (less than $1.25 per day) and 2.2 billion live on less than $2 per day which is quite disturbing situation”.  The World Health Organization (WHO) analyzed the global production of pharmaceutical products and it was concluded that 15% of the world’s population consumes over 90% of them. And by World Health Organization it is also estimated that one-third of the developing world population is unable to receive or purchase essential medicine on a regular basis, especially those which are on high demand. The situation is even worst in the under-privileged countries like Africa and Asia, where approximately 50% of the total population does not have sufficient medicines access and healthcare resources and the remaining 50% are using medication incorrectly. However about 10 million lives a year could be saved out of which 4 million in Africa and South-East Asia alone, if we improve the availability, balanced distribution and rational use of medicines. The overall situation of global access to essential medicines is still considered critical. In the privileged countries the budget for healthcare facilities corresponds to 24-66% of National health expenses, which indicates that there is need to monitor the availability and affordability of medicines in these countries. National policies, economical cost of medicine and strategies of procurement are required to ensure the availability of medicines cost-effectively. The people with low income and in-equal health can’t afford costly services of healthcare system.  The policies for the improvement of infrastructure, financing of medical system and the rational use of medicines are formulated and followed on primarily basis. And Governments need reliable information in order to evaluate the impact of policy implementation. In addition to the cost and availability of medicines, it is mandatory to assess the quality of use     and various aspects, such as rational medicine use, adherence of patients and appropriate prescription practices. Thus the access to healthcar","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy &amp; Integrated Health Sciences","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132403329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 PANDEMIC AND CHRONIC MYELOID LEUKEMIA: A REVIEW","authors":"Hafiza Sidra Bashir, Sana Ashiq, M. Sabar","doi":"10.56536/ijpihs.v3i2.39","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i2.39","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic as it has affected millions of individuals and caused hundreds of fatalities. This pandemic has posed serious challenges to health care professionals related to the treatment and management of cancer especially chronic myeloid leukemia patients. Objectives: This review has summarized some latest studies and case reports conducted to evaluate the prevalence and effects of COVID-19 infection in chronic myeloid leukemia patients and how anti-neoplastic drugs act as antiviral agents. Methodology: All the literature were searched by using different electronic databases. Results: The rate of COVID-19 infection in cancer patients is higher as compared to the normal population. The reason may be immunosuppression due to cancer progression or a therapeutic approach applied to control the progression of cancer. Studies have indicated a low risk of infection in chronic myeloid leukemia patients who received tyrosine kinase inhibitor therapy. Conclusion: It has been found that tyrosine kinase inhibitors may act as an antiviral agent. That gave the idea that anti-neoplastic agents could be repurposed as antiviral agents to fight the battle against the current pandemic. This will provide new insights into the management of COVID-19 infection in chronic myeloid leukemia patients.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy &amp; Integrated Health Sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122227340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FORMULATION AND EVALUATION OF ORAL SOLUTION FOR RHEUMATOID ARTHRITIS","authors":"Dr. Syed Muhammad Ali, A. Naz, Daniyal Saif, Haniya Tahir, Tayyab Tariq, Ehtsham Haider","doi":"10.56536/ijpihs.v3i2.29","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i2.29","url":null,"abstract":"Background: Arthritis is becoming more prevalent with time in Pakistan. An autoimmune and inflammatory condition, rheumatoid arthritis mostly affects the joints. Since most immune suppressants are injectable, it was very difficult for patients to follow their treatment regimen on a daily basis. Aims: To develop a liquid dosage form with minimal adverse drug reactions (ADRs) associated with immuno-suppressants. Methodology: For this purpose, a combination of aloe vera with anti-inflammatory effects and prednisolone with immunosuppressant effects is used. Firstly, aloe vera extract was taken and blended with distilled water, sweetened with sucralose and added in prednisolone solution along with other excipients. The results of efficacy, density, viscosity and specific gravity were as within ranges. Result: There is no discoloration and cloudiness. The results of efficacy, density, viscosity and specific gravity were as within ranges. Conclusion: Aloe juice has synergistic effects as an anti-inflammatory agent. This combination lessened the ADRs associated with prednisolone, however it doesn’t compromise the therapeutic effects.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy &amp; Integrated Health Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133325001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial of International Journal of Pharmacy and Integrated Health Sciences","authors":"Prof. Dr. Abu Bakar Munir (Ph.D.)","doi":"10.56536/ijpihs.v3i2.59","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i2.59","url":null,"abstract":"It is a great pleasure to introduce this issue on emerging ideas in health services research, biological, pharmaceutical, integrated health sciences in the International Journal of Pharmacy & Integrated Health Sciences (IJPIHS). We editor encourage studies with rigorous methodology and contributions because this is essential to ensure that the conclusions drawn from the journal's publications are true and reliable. All articles provide interesting, novel and useful results covering different areas pharmaceutical chemistry, pharmaceutics, pharmacogenomics, pharmacology, natural product research, nanotechnology, bioinformatics, biotechnology, environmental sciences and genetic engineering. The newest studies dealing with biomedical applications are summarized in this issue of IJPIHS, with \"new frontiers\" playing a crucial role in this regard. Review articles and original research covering all facets of pharmaceutical and integrated health sciences, as well as cutting-edge protocols and techniques to assess healthcare professionals' knowledge, attitudes, and practices regarding various clinical issues, are among the contributions for this issue.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy &amp; Integrated Health Sciences","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134469194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TO ASSESS THE QUALITY OF LIFE AMONG INFERTILE WOMEN: AN OBSERVATIONAL STUDY IN A MULTI-CENTER STUDY","authors":"","doi":"10.56536/ijpihs.v3i1.25","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i1.25","url":null,"abstract":"Background: Throughout the globe, at least 70 million couples suffer from the infertility of class of current prevalence. The quality of life of the females is badly affected both socially, economically and more importantly mentally due to infertility. \u0000 Objectives: The aim of the study was to assess the quality of life among infertile women. \u0000Methodology: A prospective qualitative study was conducted to assess the quality of life of infertile women. \u0000Results: 200 patients were interviewed using the questionnaire. The average results of emotional, mind/body (cognitive and physical), relational, social, environmental and tolerability are 68.97±15.358, 78.97±18.520, 50.98±8.968, 65.74±12.390, 58.79±9.054 and 76.72±21.136 respectively. \u0000Conclusion: This shows that patients undergoing assisted reproductive were disturbed both mentally and physically","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy &amp; Integrated Health Sciences","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124982503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PREVELENCE OF SECONDARY HYPERTENSION & PRESCRIBING TRENDS IN POONCH DISTRICT","authors":"","doi":"10.56536/ijpihs.v3i1.19","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i1.19","url":null,"abstract":"Background: Hypertension in pregnancy is one of the major causes of fetus and mother’s death. In pregnancy hypertension is of four categories preeclampsia, gestational hypertension, chronic hypertension, preeclampsia superimposed on chronic hypertension. \u0000Objectives: This study aims to assess prevalence of secondary hypertension and prescribing trends in Poonch district. \u0000Methodology: During the period of study in Poonch district data has been collected by lottery statistical method. Hypertension varies differently in different patients on basis of age, gender, life style. \u0000Results: Total 150 patients were considered for essential or primary hypertension, among them 100 were hypertensive. For pregnancy induced hypertension 150 patients were taken and only 50 patients had a pregnancy induce hypertension. The drug of choice in pregnancy induces hypertension are methyl dopa, beta blocker, diuretic and ACE inhibitors. In uncontrolled condition combination therapy had been used. In diabetes mellitus induced hypertension, 150 patients were selected and 50 were those who had hypertension. In kidney disease only 15 patients had renal disease induce hypertension. \u0000Conclusion: The study describes prescribing trends for secondary hypertension in district Poonch, Kashmir.","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy &amp; Integrated Health Sciences","volume":"2675 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116638183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PHYTOCHEMICAL AND PHARMACOLOGICAL ATTRIBUTES OF SALVADORA PERSICA WITH SPECIAL REFERENCE TO ITS TRADITIONAL USES – A SYSTEMATIC REVIEW","authors":"","doi":"10.56536/ijpihs.v3i1.20","DOIUrl":"https://doi.org/10.56536/ijpihs.v3i1.20","url":null,"abstract":"Background: Salvadora persica (Salvadoraceae) also known as miswak, pelu, meethi jaal and kharijaal, is an ethno-medicinal plant which grows in Middle East, tropical and subtropical regions of Africa and Asia extending up to China and Japan. \u0000Objectives: This study is designed to document a complete profile of the plant which is previously published. \u0000Methodology: The articles published between the duration of 2002-2021 were reviewed with the help of different databases \u0000Results: In traditional medicine, the stems, branches, leaves, seeds and roots of Salvadora persica are used for oral hygiene, as carminative, astringent, diuretic, analgesic, antitussive, against toothache, skin diseases, rheumatism, scurvy, piles, and hepatic disorders. It is an evergreen shrub that exhibits pharmacological effects such ashypoglycemic effects, anti-bacterial activity, anti-oxidant activity, anti-ulcerogenic activity, anti-caries effect, hypo-cholestremia effect, anti-fungal activity and anti-depressant activity. There are various phytochemicals present in Salvadora persica which are biologically active. These phyto-constituents are volatile oils, piperidine derivatives, terpenoids, fixed oils, steroids, alkaloids, saponins, tannins and organic acids.The present review offers a detailed survey on literature highlighting the traditional, pharmacognostic and pharmacological uses of Salvadora persica. \u0000Conclusion: The plant has many important therapeutic activities further research is needed to ensure safety and efficacy","PeriodicalId":142550,"journal":{"name":"International Journal of Pharmacy &amp; Integrated Health Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122517195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}