International Journal of Neuroscience最新文献

{"title":"<i>DHDDS</i>-related disease; biallelic missense novel variant causing major severity with an early-onset epilepsy and hyperkinetic movement disorder.","authors":"Hande Gazeteci Tekin, Pınar Edem","doi":"10.1080/00207454.2024.2327405","DOIUrl":"10.1080/00207454.2024.2327405","url":null,"abstract":"<p><strong>Background: </strong>Dehydrodolichyl diphosphate synthase complex is encoded by <i>DHDDS. De novo</i> mutations in this gene are associated with epilepsy, movement disorders, intellectual and motor disabilities. The clinical picture is commonly identified in children and shows variations in terms of age of onset, severity, seizure types, and types of dyskinesia.</p><p><strong>Case: </strong>we present a case with a infantile- onset epilepsy and severe global developmental delay, caused by a novel, <i>de novo</i> homozygous variant (c.425C > T, p.Thr142Met) in <i>DHDDS</i>. Clinical improvement was achieved with valproate and tetrabenazine treatments in the 2-year-old male patient with drug-resistant epilepsy, hyperkinetic movement disorder and myoclonus.</p><p><strong>Conclusion: </strong>Despite being rare, DHDDS-related diseases should be considered in patients with movement disorders, seizures and global developmental delay in infancy in differential diagnosis of patients resembling neuronal ceroid lipofuscinosis or progressive myoclonic epilepsies.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"726-730"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140049428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroacupuncture attenuates middle cerebral artery occlusion-induced learning and memory impairment by regulating microglial polarization in hippocampus.","authors":"Qiong Wen, Fubing Zha, Linlin Shan, Shaohua Zhang, Peng Xiao, Chunxia Zhang, Haibo Yu, Yulong Wang","doi":"10.1080/00207454.2024.2313664","DOIUrl":"10.1080/00207454.2024.2313664","url":null,"abstract":"<p><strong>Background: </strong>As a traditional medical therapy, electroacupuncture (EA) has been demonstrated to have beneficial effects on ischemic stroke-induced cognitive impairment. However, the underlying mechanism is largely unclear.</p><p><strong>Methods: </strong>Adult rats received occlusion of the middle cerebral artery and reperfusion (MCAO/R) to establish the ischemic stroke model. Morris water maze test was performed following EA stimulation at the GV20, PC6, and KI1 acupoints in rats to test the learning and memory ability. Western blot, immunofluorescent staining, and enzyme-linked immunosorbent assay were conducted to assess the cellular and molecular mechanisms.</p><p><strong>Results: </strong>EA stimulation attenuated neurological deficits. In the Morris water maze test, EA treatment ameliorated the MCAO/R-induced learning and memory impairment. Moreover, we observed that MCAO/R induced microglial activation and polarization in the ischemic hippocampus, whereas, EA treatment dampened microglial activation and inhibited M1 microglial polarization but enhanced M2 microglial polarization. EA treatment inhibited the increased expression of proinflammatory cytokines and enhanced the increased expression of anti-inflammatory cytokines. Finally, we found that EA treatment dampened microglial p38 mitogen-activated protein kinase (MAPK) phosphorylation.</p><p><strong>Conclusion: </strong>Collectively, our data suggested that EA treatment ameliorated cognitive impairment induced by MCAO/R and the underlying mechanism may be <i>p</i>38-mediated microglia polarization and neuroinflammation.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"626-638"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing the incidence of persistent headache attributed to retrosigmoid craniotomy: the role of 3D computed tomography venography image-guided technique and bone defects minimization.","authors":"Li Li, Bing Fang, Hong Zhang, Hemmings Wu, Gao Chen","doi":"10.1080/00207454.2024.2324018","DOIUrl":"10.1080/00207454.2024.2324018","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this paper was to assess the risk factors for persistent headache attributed to retrosigmoid craniotomy. Furthermore, we evaluated the role of the 3D computed tomography venography(CTV) image-guided technique in reducing the incidence of persistent headache.</p><p><strong>Method: </strong>The study encompassed patients with trigeminal neuralgia who underwent microvascular decompression. Patients were categorized into two groups based on the use of 3D CTV in surgical planning. Factors related to craniotomy and postoperative complications were analyzed between the two groups. Binary logistic regression analysis was conducted to identify risk factors for persistent headache attributed to craniotomy.</p><p><strong>Result: </strong>The inclusion criteria yielded 48 patients who underwent craniotomy with 3D CTV image guidance (the image-guided group) and 69 patients who did not use this technique (the control group). The image-guided group experienced significantly shorter craniotomy durations (27.9 ± 4.7 vs. 37.5 ± 8.0 min; <i>p</i> < 0.001), smaller craniotomy areas (472.7 ± 56.7 vs. 617.4 ± 89.7 mm²; <i>p</i> < 0.001), and reduced bone defects (141.8 ± 33.5 vs. 233.2 ± 71.1 mm²; <i>p</i> < 0.001). Bone defect (OR: 1.012; 95% CI: 1.005-1.018; <i>p</i> < 0.001) was found to be significantly associated with persistent headache in the multivariate analysis.</p><p><strong>Conclusions: </strong>Bone defects constitute an independent risk factor for persistent headache attributed to retrosigmoid craniotomy. The 3D CTV image-guided technique effectively reduces the size of bone defects, thereby leading to a reduced incidence of persistent headache postoperatively.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"658-664"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140131374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Daiwenjiu ointment on the treatment of cervical spondylosis with nerve root type caused by cold dampness obstruction.","authors":"Xinnian Guo, Suotang Kou, Bai Yang, Wenjun Zhu, Junfeng Zhang","doi":"10.1080/00207454.2024.2324026","DOIUrl":"10.1080/00207454.2024.2324026","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the clinical efficacy of Daiwenjiu ointment in the treatment of cervical spondylosis with cold dampness obstruction nerve root type.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on a cohort of 110 patients diagnosed with cervical spondylotic radiculopathy. Based on the treatment method, the patients were divided into two groups. The control group received electroacupuncture treatment, while the observation group received a combination of Daiwenjiu ointment and electroacupuncture treatment. The outcome measures included Japanese Orthopedic Association (JOA) scores for cervical spine function, Simplified McGill Pain Questionnaire (SF-MPQ) scores, and changes in serum inflammatory factors TNF-α and IL-1β.</p><p><strong>Results: </strong>Following treatment, the JOA score in the observation group increased from 9.45 ± 1.35 to 14.82 ± 1.29 after treatment, indicating better recovery of cervical spine function compared to the control group (<i>p</i> < 0.001). The SF-MPQ score in the observation group decreased to 18.25 ± 3.80 after treatment, while it remained at 30.20 ± 4.30 in the control group. This difference between the groups was statistically significant (<i>p</i> < 0.001). Furthermore, the observation group demonstrated a significant decrease in serum levels of TNF-α and IL-1β after treatment compared to the control group (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Daiwenjiu ointment exhibits significant therapeutic effects in patients with cold dampness obstruction nerve root type cervical spondylosis. It effectively improves cervical function, reduces pain, and downregulates inflammatory cytokine levels.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"665-672"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139944161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of biofeedback intervention on neurological characteristics of children with attention deficit hyperactivity disorder.","authors":"Cai Zhang, Xiaoxuan Zhou, Nanfei Hu, Lin Xu","doi":"10.1080/00207454.2024.2325029","DOIUrl":"10.1080/00207454.2024.2325029","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effects of biofeedback intervention on the neurological characteristics of children with attention deficit hyperactivity disorder (ADHD).</p><p><strong>Methods: </strong>150 children aged 6-12 years with ADHD were divided into two groups according to the treatment method. The atomoxetine group received atomoxetine drug treatment, and the combined treatment group received EEG biofeedback therapy. Continuous performance test (CPT), SNAP-IV and WFIRS-P were used to assess attention and behavior, and functional magnetic resonance imaging (fMRI) was used to observe changes in brain activity.</p><p><strong>Results: </strong>The response time, error times, error response rate and attention fluctuation index of CPT in the combined treatment group were significantly lower than those in the atomoxetine group (<i>p <</i> 0.05), and the correct response rate was higher than that in the atomoxetine group (<i>p <</i> 0.05). After intervention, SNAP-IV and WFIRS-P scores in the combined treatment group were significantly lower than those in the atomoxetine group (<i>p <</i> 0.001). fMRI results showed that the activity of the prefrontal, parietal, amygdala and hippocampus in the combined treatment group was significantly higher than that in the atomoxetine group (<i>p <</i> 0.001).</p><p><strong>Conclusion: </strong>Biofeedback intervention can significantly improve the attention and behavior of ADHD children and positively regulate the neural activity in related brain areas on the basis of drug treatment, suggesting that biofeedback therapy can be considered as a potential effective nondrug treatment option for ADHD children.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"684-691"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139990011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Processing speed and executive functioning in relation to off-topic verbosity among young adults and older adults.","authors":"Michael D Barnett, Leah N Smith, Allyson M Coldiron","doi":"10.1080/00207454.2024.2327401","DOIUrl":"10.1080/00207454.2024.2327401","url":null,"abstract":"<p><strong>Purpose: </strong>Off-topic verbosity (OTV) is a tendency towards excessive, off-topic speech and has been linked with age-related deficits in executive functioning, particularly inhibition. However, there are numerous disagreements within the literature on what constitutes OTV, and there is a further lack of investigation into alternative cognitive explanations for the link between inhibition and OTV. The purpose of this study was to investigate the speech characteristics of OTV in young and older adults as well as to examine whether variations in OTV are better explained by diminished executive functioning or processing speed, as measured by the D-KEFS Stroop test.</p><p><strong>Methods: </strong>Young adults (<i>n</i> = 65; age 18-28) and older adults (<i>n</i> = 85; age 60-98) completed the D-KEFS Color-Word Interference Test and provided verbal samples of autobiographical episodic and procedural speech. These speech samples were rated on three facets of OTV: tangentiality, egocentrism and quantity of speech.</p><p><strong>Results: </strong>Procedural autobiographical speech was found to best measure age cohort variations in OTV, and higher OTV was associated with poorer Stroop test performance in older adults but not in young adults. In fact, young adults only displayed associations between poorer Stroop performance and a reduction in speech quantity. Finally, processing speed deficits were more associated with increased OTV in older adults than executive functioning.</p><p><strong>Conclusion: </strong>These results provide support for links between age-related cognitive decline and OTV, but the results suggest that processing speed may be more implicated than executive functioning.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"701-708"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140158111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of urokinase and alteplase intravenous thrombolysis in the treatment of acute phase cerebral infarction and impact on serum S-100β and nerve growth factor levels.","authors":"Lei Zhang, Si Wang, Nannan Ren","doi":"10.1080/00207454.2024.2322137","DOIUrl":"10.1080/00207454.2024.2322137","url":null,"abstract":"<p><strong>Objective: </strong>To compare the efficacy of urokinase and alteplase intravenous thrombolysis in the treatment of acute phase cerebral infarction and investigate their impact on serum S-100β and nerve growth factor (NGF) levels.</p><p><strong>Methods: </strong>Parameters assessed included NIHSS score reduction, vascular recanalization rates, mRS, Barthel Index, and adverse reactions. Post-treatment blood samples were also collected for further analysis.</p><p><strong>Results: </strong>The clinical treatment effectiveness and Vascular recanalization rate in Group A was higher than in Group B, with <i>p</i> < 0.05. After treatment, the NIHSS score in Group A was lower than in Group B (<i>p</i> < 0.05), and the mRS score was slightly lower, but the difference was not significant (<i>p</i> > 0.05). After treatment, the levels of IL-6, TNF-α, and CRP in Group A were lower than in the control group (<i>p</i> < 0.05). The S-100β level in Group A was lower than in Group B, and NGF level was higher than in Group B (<i>p</i> < 0.05). Group A had better prognosis.</p><p><strong>Conclusion: </strong>The efficacy and safety of both urokinase and alteplase intravenous thrombolysis for acute phase cerebral infarction have been demonstrated, yet disparities exist in neurological function recovery and regulation of biochemical indicators. Alteplase intravenous thrombolysis emerges as the superior option, displaying greater effectiveness and safety, alongside improved regulation of serum S-100β and NGF levels. Tailoring treatment plans to individual patient characteristics and drug mechanisms is essential. Given these findings, the promotion of alteplase intravenous thrombolysis in the management of acute phase cerebral infarction is justified.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"650-657"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139905625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of RNA pseudouridine modification in nervous system.","authors":"Hui Chen, Shuang Zhao","doi":"10.1080/00207454.2024.2315483","DOIUrl":"10.1080/00207454.2024.2315483","url":null,"abstract":"<p><p>Recent advances of pseudouridine (Ψ, 5-ribosyluracil) modification highlight its crucial role as a post-transcriptional regulator in gene expression and its impact on various RNA processes. Ψ synthase (PUS), a category of RNA-modifying enzymes, orchestrates the pseudouridylation reaction. It can specifically recognize conserved sequences or structural motifs within substrates, thereby regulating the biological function of various RNA molecules accurately. Our comprehensive review underscored the close association of PUS1, PUS3, PUS7, PUS10, and dyskerin PUS1 with various nervous system disorders, including neurodevelopmental disorders, nervous system tumors, mitochondrial myopathy, lactic acidosis and sideroblastic anaemia (MLASA) syndrome, peripheral nervous system disorders, and type II myotonic dystrophy. In light of these findings, this study elucidated how Ψ strengthened RNA structures and contributed to RNA function, thereby providing valuable insights into the intricate molecular mechanisms underlying nervous system diseases. However, the detailed effects and mechanisms of PUS on neuron remain elusive. This lack of mechanistic understanding poses a substantial obstacle to the development of therapeutic approaches for various neurological disorders based on Ψ modification.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"639-649"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139971803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a relationship between sphenoid sinus pneumatization and carotid canal-intersinus septa connection?","authors":"Adnan Özdemir, Nuray Bayar Muluk, Ziya Şencan","doi":"10.1080/00207454.2024.2313011","DOIUrl":"10.1080/00207454.2024.2313011","url":null,"abstract":"<p><strong>Objectives: </strong>We investigated the relationship between sphenoid sinus (SS) pneumatization types, carotid canal types and carotid canal-intersinus septa connection.</p><p><strong>Methods: </strong>The paranasal sinus computed tomography (PNSCT) images of 274 patients (141 males and 133 females) were evaluated retrospectively. SS pneumatization, SS intersinus septation, SS intersinus septa deviation, carotid canal classification, carotid canal dehiscence, carotid canal-intersinus septa connection and presence of Onodi cells were evaluated.</p><p><strong>Results: </strong>In presellar and sellar SS, type 1 carotid canal was detected. However, type 3 carotid canal was detected more in postsellar SS. On the left side, in 26.4% of the postsellar SS, carotid canal dehiscence was detected. On the right side, carotid canal-intersinus septa connection was detected in 55.8% of the postsellar SS and 35.1% of the sellar SS. On the left side, it was detected 58.3% of the postsellar SS and 30.9% of the sellar SS. In postsellar type SS pneumatized cases, right caroid canal-intersinus septa connection increased by 5.4 fold and left carotid canal-intersinus septa connection increased by 7.3 fold compared to presellar type SS pneumatization. In 2≥ intersinus septa group, left carotid canal-intersinus septa connection increased 5.0 fold compared to 'no septa' group.</p><p><strong>Conclusion: </strong>In this study, we evaluated SS pneumatization types and their relation with carotid canal types and carotid canal-intersinus septa connections. Type 3 carotid canal (protrudation to SS wall) was detected more in postsellar SS. In these cases, surgeons should be very careful during surgery to avoid damage to the internal carotid artery (ICA).</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"599-606"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring autonomic responses in Parkinson's disease individuals: non-linear and chaotic global metrics of heart rate variability.","authors":"Heloisa Balotari Valente, Natacha de Lima Gervazoni, Maria Júlia Lopez Laurino, Mileide Cristina Stoco-Oliveira, Felipe Ribeiro, Augusto Cesinando de Carvalho, Luiz Carlos Marques Vanderlei, David M Garner","doi":"10.1080/00207454.2024.2325020","DOIUrl":"10.1080/00207454.2024.2325020","url":null,"abstract":"<p><strong>Aim: </strong>To examine and compare the autonomic responses, as assessed through the non-linear and chaotic global metrics of heart rate variability in two groups: the Parkinson's Disease Group (PDG) and the Control Group (CG), both at rest and during an active tilt test.</p><p><strong>Methods: </strong>The study encompassed 46 participants (PDG: <i>n</i> = 23; 73.73 ± 7.28 years old; CG: <i>n</i> = 23; 70.17 ± 8.20 years old). Initial data collection involved the acquisition of participant's characteristics. The autonomic modulation was estimated both at rest and during the active tilt test. For this assessment, we computed non-linear indices derived from five entropies (Approximate, Sample, Shannon, Renyi, Tsallis), Detrended Fluctuation Analysis and the seven chaotic global metrics (<i>hs</i>CFP1-<i>hs</i>CFP7).</p><p><strong>Results: </strong>At rest, the PDG exhibited lower values of <i>hs</i>CFP3 (0.818 ± 0.116 vs. 0.904 ± 0.065; <i>p</i> < 0.05) and Sample Entropy (0.720 ± 0.149 vs. 0.799 ± 0.171; <i>p</i> < 0.05). During the test, the PDG demonstrated lower values of ApEn, while the CG presented lower values of SampEn, <i>hs</i>CFP1, <i>hs</i>CFP3, <i>hs</i>CFP7, and higher values of <i>hs</i>CFP5. An interaction was observed, indicating that <i>hs</i>CFP1 and <i>hs</i>CFP3 exhibit differential behavior for the CG and PDG in response to the test.</p><p><strong>Conclusion: </strong>subjects with PD exhibited reduced complexity of the RR interval series at rest, and a diminished autonomic response to the active tilt test when compared with the CG. The test, together with non-linear indices, may serve for assessing the Autonomic Nervous System in individuals with PD in a clinical setting. The interpretation of these data should be approached with caution, given the possible influences of pharmacotherapies and the inclusion of diabetic participants.</p>","PeriodicalId":14161,"journal":{"name":"International Journal of Neuroscience","volume":" ","pages":"673-683"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}