International Journal of Infectious Diseases最新文献

筛选
英文 中文
Significant rise of Chlamydia pneumoniae infection in 2024 in Marseille, France 2024 年法国马赛的肺炎衣原体感染率显著上升。
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-04-01 DOI: 10.1016/j.ijid.2025.107897
Sophie Edouard , Rayane Attamna , Matthieu Million , Céline Boschi , Jeremy Delerce , Aurélia Caputo , Didier Stoupan , Seydina Diene , Idir Kacel , Claudia Andrieu , Anthony Levasseur , Hervé Chaudet , Jean-Marc Rolain , Lucile Lesage , Aurélie Morand , Pierre-Edouard Fournier , Jean-Christophe Lagier , Florence Fenollar , Bernard La Scola , Philippe Colson
{"title":"Significant rise of Chlamydia pneumoniae infection in 2024 in Marseille, France","authors":"Sophie Edouard ,&nbsp;Rayane Attamna ,&nbsp;Matthieu Million ,&nbsp;Céline Boschi ,&nbsp;Jeremy Delerce ,&nbsp;Aurélia Caputo ,&nbsp;Didier Stoupan ,&nbsp;Seydina Diene ,&nbsp;Idir Kacel ,&nbsp;Claudia Andrieu ,&nbsp;Anthony Levasseur ,&nbsp;Hervé Chaudet ,&nbsp;Jean-Marc Rolain ,&nbsp;Lucile Lesage ,&nbsp;Aurélie Morand ,&nbsp;Pierre-Edouard Fournier ,&nbsp;Jean-Christophe Lagier ,&nbsp;Florence Fenollar ,&nbsp;Bernard La Scola ,&nbsp;Philippe Colson","doi":"10.1016/j.ijid.2025.107897","DOIUrl":"10.1016/j.ijid.2025.107897","url":null,"abstract":"<div><h3>Objectives</h3><div>We detected in October 2024 an abnormally high number of <em>Chlamydia pneumoniae</em> diagnoses through real-time surveillance of infections in Southeastern France, which followed significant increases in <em>Mycoplasma pneumoniae</em> and <em>Bordetella pertussis</em> diagnoses. Therefore, we retrospectively analyzed <em>C. pneumoniae</em> quantitative polymerase chain reaction (qPCR) results performed on respiratory samples collected between 2018 and 2024 in our center and described features of these infections.</div></div><div><h3>Methods</h3><div><em>C. pneumoniae</em> qPCR was part from a multiplex syndromic panel or an in-house simplex qPCR assay. Next-generation sequencing was performed directly on available respiratory sample residues using Oxford Nanopore/Illumina technologies.</div></div><div><h3>Results</h3><div>We observed a 19-fold increase of <em>C. pneumoniae</em> qPCR positivity in 2024 vs 2018-2023. Five (0.02%) of 25,255 respiratory samples were positive during 2018-2022, five (0.12%) of 4294 in 2023, and 37 (0.64%) of 5795 in 2024 (21 during September to October). Cases were mostly in children, followed by young adults. The highest incidence was in children aged 11-15 years (eight of 1075, 0.7%) and 6-10 years (eight of 1669, 0.5%). We obtained four (near) full-length <em>C. pneumoniae</em> genomes. They were of serotype ST16 and those the most closely related with each other, apart from the six other ST16 genomes from GenBank, suggesting an epidemic spread in our area.</div></div><div><h3>Conclusions</h3><div>The present findings warrant a close monitoring of diagnoses of <em>C. pneumoniae</em> infections at the local and country scales and to implement genomic surveillance and characterize drug resistance for diagnosed cases.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107897"},"PeriodicalIF":4.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global Resurgence of Measles: Turning the Tide through a Bold Agenda for Prevention and Control 全球麻疹死灰复燃:通过大胆的预防和控制议程扭转局势。
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-31 DOI: 10.1016/j.ijid.2025.107901
Evans Mpabalwani , Giuseppe Ippolito , Danny Asogun , Eleni Aklillu , Markus Maeurer , Shui Shan Lee , Alimuddin Zumla
{"title":"Global Resurgence of Measles: Turning the Tide through a Bold Agenda for Prevention and Control","authors":"Evans Mpabalwani ,&nbsp;Giuseppe Ippolito ,&nbsp;Danny Asogun ,&nbsp;Eleni Aklillu ,&nbsp;Markus Maeurer ,&nbsp;Shui Shan Lee ,&nbsp;Alimuddin Zumla","doi":"10.1016/j.ijid.2025.107901","DOIUrl":"10.1016/j.ijid.2025.107901","url":null,"abstract":"","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107901"},"PeriodicalIF":4.8,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Year-round infectome profiling of acute febrile respiratory illness unveiled complex epidemiological dynamics postlifting of COVID-19 restrictions 急性发热性呼吸道疾病全年感染组分析揭示了解除COVID-19限制后复杂的流行病学动态。
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-29 DOI: 10.1016/j.ijid.2025.107896
Shisong Fang , Lin Zhu , Shaohui Bai , Weijian Tian , Yuanfei Pan , Shumiao Zhang , Rongjun Bi , Minqi Liang , Gengyan Luo , Xiaojing Chen , Minwu Peng , Hanlin Liu , Lu Xie , Runzi Zhang , Wudi Zhou , Shengze Zhang , Ting Xie , Haolu Zha , Chuming Luo , Xin Wang , Huanle Luo
{"title":"Year-round infectome profiling of acute febrile respiratory illness unveiled complex epidemiological dynamics postlifting of COVID-19 restrictions","authors":"Shisong Fang ,&nbsp;Lin Zhu ,&nbsp;Shaohui Bai ,&nbsp;Weijian Tian ,&nbsp;Yuanfei Pan ,&nbsp;Shumiao Zhang ,&nbsp;Rongjun Bi ,&nbsp;Minqi Liang ,&nbsp;Gengyan Luo ,&nbsp;Xiaojing Chen ,&nbsp;Minwu Peng ,&nbsp;Hanlin Liu ,&nbsp;Lu Xie ,&nbsp;Runzi Zhang ,&nbsp;Wudi Zhou ,&nbsp;Shengze Zhang ,&nbsp;Ting Xie ,&nbsp;Haolu Zha ,&nbsp;Chuming Luo ,&nbsp;Xin Wang ,&nbsp;Huanle Luo","doi":"10.1016/j.ijid.2025.107896","DOIUrl":"10.1016/j.ijid.2025.107896","url":null,"abstract":"<div><h3>Objectives</h3><div>Following the lifting of COVID-19 nonpharmaceutical interventions in China, respiratory infections surged, though the specific causes remained unclear. This study provided a comprehensive overview of the infectome in patients with acute febrile respiratory illness (AFRI) to inform disease surveillance.</div></div><div><h3>Methods</h3><div>Between March 2023 and February 2024, 1163 oropharyngeal swabs from AFRI patients and 338 from healthy individuals were collected in Shenzhen. Meta-transcriptomic sequencing was employed for microbial analysis.</div></div><div><h3>Results</h3><div>We identified 14 viruses and 10 bacteria species known to cause human disease. Influenza virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), <em>Streptococcus pneumoniae</em>, and redondovirus were the most common, with a negative correlation between H3N2 and SARS-CoV-2. Notably, we detected certain enterovirus subtypes (e.g., Coxsackievirus A6 and Echovirus 30), previously overlooked pathogens (e.g., redondovirus), and rare pathogens like <em>Streptococcus pseudopneumoniae</em>. Comparisons revealed five pathogens showed significantly higher abundance in patients than in controls, despite no significant differences for others probably due to their limited number of positive pools. Seasonal shifts in microbial diversity and composition were observed, with climate factors like temperature and precipitation playing a role. Phylogenetic analysis revealed changes in genotype diversity and dominant pathogen lineages.</div></div><div><h3>Conclusion</h3><div>This study highlighted complex pathogen infections in AFRI patients following COVID-19 restrictions, demonstrating the value of meta-transcriptomics over PCR-based methods for more detailed pathogen surveillance.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107896"},"PeriodicalIF":4.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
One-year mortality of tuberculosis patients on isoniazid-based treatment and its association with rapid acetylator NAT2 genotypes 异烟肼治疗结核病患者一年死亡率及其与快速乙酰化剂NAT2基因型的关系
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-25 DOI: 10.1016/j.ijid.2025.107895
Ayu Kasamatsu , Reiko Miyahara , Daisuke Yoneoka , Licht Toyo-oka , Boonchai Chiyasirinroje , Worarat Imsanguan , Supharat Suvichapanich , Hideki Yanai , Sukanya Wattnapokayakit , Supalert Nedsuwan , Manon Boonbangyang , Prasit Palittapongarnpim , Katsushi Tokunaga , Taisei Mushiroda , Surakameth Mahasirimongkol
{"title":"One-year mortality of tuberculosis patients on isoniazid-based treatment and its association with rapid acetylator NAT2 genotypes","authors":"Ayu Kasamatsu ,&nbsp;Reiko Miyahara ,&nbsp;Daisuke Yoneoka ,&nbsp;Licht Toyo-oka ,&nbsp;Boonchai Chiyasirinroje ,&nbsp;Worarat Imsanguan ,&nbsp;Supharat Suvichapanich ,&nbsp;Hideki Yanai ,&nbsp;Sukanya Wattnapokayakit ,&nbsp;Supalert Nedsuwan ,&nbsp;Manon Boonbangyang ,&nbsp;Prasit Palittapongarnpim ,&nbsp;Katsushi Tokunaga ,&nbsp;Taisei Mushiroda ,&nbsp;Surakameth Mahasirimongkol","doi":"10.1016/j.ijid.2025.107895","DOIUrl":"10.1016/j.ijid.2025.107895","url":null,"abstract":"<div><h3>Background</h3><div><em>NAT2</em> polymorphisms affect isoniazid metabolism, but their effect on mortality among individuals with tuberculosis (TB) remains unclear.</div></div><div><h3>Methods</h3><div>This study used data from two TB cohorts (2005–2011, 2014–2020) and death certificate records in Thailand. Newly diagnosed Thai individuals treated with isoniazid-containing regimens were included. <em>NAT2</em> genotypes—rapid, intermediate, and slow acetylator (RA, IA, SA)—were classified via haplotype inference. The primary outcome was 1-year all-cause mortality, while secondary outcomes included TB-related mortality, TB+respiratory disease-related mortality recorded in the vital registration system, and death as a TB treatment outcome. Adjusted hazard ratios (aHRs) relative to the IA type were estimated using stratified Cox proportional hazards models. Subgroup analyses targeted individuals with isoniazid-resistant TB and HIV infection.</div></div><div><h3>Results</h3><div>A total of 1,065 individuals (766 males; mean age=51 years) were analyzed. Individuals with RA had a 1.70-fold greater all-cause mortality risk (95 % CI: 1.03–2.80) than IA. The aHRs for RA were 1.14 (0.43–3.03) for TB-related mortality, 1.59 (0.80–3.18) for TB+respiratory disease-related mortality, and 1.26 (0.67–2.37) for TB treatment outcome death. Among individuals with isoniazid-resistant TB, those with RA had a 4.68-fold (1.14–19.12) greater aHR for all-cause mortality.</div></div><div><h3>Conclusion</h3><div>The RA type is associated with increased 1-year all-cause mortality.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107895"},"PeriodicalIF":4.8,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudomonas aeruginosa community-acquired pneumonia following soil ingestion: A case report 土壤摄食后铜绿假单胞菌社区获得性肺炎1例报告。
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-21 DOI: 10.1016/j.ijid.2025.107894
Ying Chen , Juanjuan Wu , Hui Tong , Di Xu , Cong Wei , Shi Chen , Li Chen , Chenghong Li , Shuang Liu , Fajiu Li
{"title":"Pseudomonas aeruginosa community-acquired pneumonia following soil ingestion: A case report","authors":"Ying Chen ,&nbsp;Juanjuan Wu ,&nbsp;Hui Tong ,&nbsp;Di Xu ,&nbsp;Cong Wei ,&nbsp;Shi Chen ,&nbsp;Li Chen ,&nbsp;Chenghong Li ,&nbsp;Shuang Liu ,&nbsp;Fajiu Li","doi":"10.1016/j.ijid.2025.107894","DOIUrl":"10.1016/j.ijid.2025.107894","url":null,"abstract":"<div><h3>Background</h3><div><em>Pseudomonas aeruginosa</em> (<em>P. aeruginosa)</em> is an uncommon etiological agent in community-acquired pneumonia (CAP), typically associated with nosocomial or healthcare-associated infections, particularly in patients with underlying structural lung abnormalities or immunosuppression. <em>P. aeruginosa</em> is a ubiquitous gram-negative rod, widely distributed in the environment. However, CAP due to <em>P. aeruginosa</em> following soil ingestion is exceedingly rare.</div></div><div><h3>Case presentation</h3><div>We present the case of a previously healthy 31-year-old patient, a middle school teacher, who developed CAP due to <em>P. aeruginosa</em> after ingesting garden soil for three consecutive days. The patient was admitted with symptoms including fever, chest pain, vomiting, and diarrhea. Chest computed tomography (CT) revealed two suspicious lesions in the left lower lobe, with one lesion exhibiting cavitation. Microbiological culture of bronchoalveolar lavage fluid (BALF) and stool confirmed the presence of <em>P. aeruginosa</em> infection. Subsequent antimicrobial susceptibility testing revealed that the <em>P. aeruginosa</em> isolate was pan-sensitive. Following 13 days of targeted antimicrobial therapy, the patient's symptoms and laboratory markers of infection improved significantly. A follow-up CT scan one month later demonstrated substantial resolution of the left lower lobe lesions, and the patient remained asymptomatic.</div></div><div><h3>Conclusions</h3><div>This case, along with a review of related literature, suggests that geophagy may be a potential risk factor for <em>P. aeruginosa</em> infection. It underscores the importance of avoiding the consumption of unprocessed soil, which may be contaminated with pathogenic organisms.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107894"},"PeriodicalIF":4.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Helicobacter pylori multiplex serology and its dynamics within families during a 3-year prospective follow-up 幽门螺杆菌(Hp)多重血清学及其在家庭中的动态三年前瞻性随访。
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-20 DOI: 10.1016/j.ijid.2025.107893
Kari Syrjänen , Sanni Rinne , Nea Koskela , Birgitta Michels , Julia Butt , Seija Grénman , Tim Waterboer , Stina Syrjänen , Karolina Louvanto
{"title":"Helicobacter pylori multiplex serology and its dynamics within families during a 3-year prospective follow-up","authors":"Kari Syrjänen ,&nbsp;Sanni Rinne ,&nbsp;Nea Koskela ,&nbsp;Birgitta Michels ,&nbsp;Julia Butt ,&nbsp;Seija Grénman ,&nbsp;Tim Waterboer ,&nbsp;Stina Syrjänen ,&nbsp;Karolina Louvanto","doi":"10.1016/j.ijid.2025.107893","DOIUrl":"10.1016/j.ijid.2025.107893","url":null,"abstract":"<div><h3>Objectives</h3><div>Transmission routes of <em>Helicobacter pylori</em> (<em>Hp</em>) have been extensively studied, but many aspects remain unclear. This study explored the dynamics of multiplex <em>Hp</em> serology within regular families during a 36-month prospective follow-up.</div></div><div><h3>Methods</h3><div>Altogether, 329 families from the Finnish Family HPV study were subjected to sequential blood sampling and now tested also for six <em>Hp</em> proteins, HP0010, HP0073, HP0547, HP0875, HP0887, and HP1564, using multiplex serology assay.</div></div><div><h3>Results</h3><div><em>Hp</em> seropositivity, defined as being seropositive to at least three of the six <em>Hp</em> proteins, was more common among the fathers (20%) than mothers (10%). After maternal antibody decay, only a few children tested <em>Hp</em>-seropositive at later follow-up visits, indicating that acquisition of <em>Hp</em> infection is practically non-existent (0.4-2.0%) at an early age. No evidence was found to support the person-to-person transmission of <em>Hp</em> in this cohort because there was no correlation in <em>Hp</em> seropositivity or antibody levels between the spouses and/or their offspring, and individuals who were <em>Hp</em>-seropositive did not seem to increase the risk of other family members to co-test <em>Hp</em>-seropositive.</div></div><div><h3>Conclusions</h3><div>Our results perfectly agree with a recently published register-linkage study from Finland, where <em>Hp</em> and <em>Hp</em>-related co-morbidity are predicted to disappear among the native Finns during the 21<sup>st</sup> century.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107893"},"PeriodicalIF":4.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point-of-care testing reduces antibiotic prescribing in acute exacerbations of chronic obstructive pulmonary disease: A systematic review and meta-analysis 即时检测减少慢性阻塞性肺疾病急性加重的抗生素处方:一项系统回顾和荟萃分析
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-19 DOI: 10.1016/j.ijid.2025.107889
Xiying Li , Shengyue Qiu , Chaojie Liu , Manzhi Zhao , Xinyi Yang , Haohai Xia , Ruonan Wang , Shanquan Chen , Jie Chen , Jinkun Zheng , Gordon Liu , Shifang Yang , Lianping Yang , Christopher C Butler
{"title":"Point-of-care testing reduces antibiotic prescribing in acute exacerbations of chronic obstructive pulmonary disease: A systematic review and meta-analysis","authors":"Xiying Li ,&nbsp;Shengyue Qiu ,&nbsp;Chaojie Liu ,&nbsp;Manzhi Zhao ,&nbsp;Xinyi Yang ,&nbsp;Haohai Xia ,&nbsp;Ruonan Wang ,&nbsp;Shanquan Chen ,&nbsp;Jie Chen ,&nbsp;Jinkun Zheng ,&nbsp;Gordon Liu ,&nbsp;Shifang Yang ,&nbsp;Lianping Yang ,&nbsp;Christopher C Butler","doi":"10.1016/j.ijid.2025.107889","DOIUrl":"10.1016/j.ijid.2025.107889","url":null,"abstract":"<div><h3>Background</h3><div>Challenges in identifying the causes of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have led to overuse of antibiotics. The advantages of point-of-care testing (POCT) may help to identify pathogens and use antibiotics more appropriately.</div></div><div><h3>Methods</h3><div>We conducted a systematic review to evaluate the effect of POCT to guide antibiotic prescriptions for AECOPD. Adhering to a protocol (CRD42024555847), we searched eligible studies. The outcomes included antibiotic-related and clinical outcomes. We evaluated the risk of bias and performed meta-analyses with subgroup based on the type and testing timing of POCT.</div></div><div><h3>Results</h3><div>A total of 18 studies evaluating 4346 AECOPD patients were included. Overall, POCT significantly reduced the number of AECOPD patients given antibiotic prescriptions by 16% (<em>P</em> &lt; 0.001). Additionally, antibiotic treatment was reduced by 1.19 days (<em>P</em> = 0.04). There was no detrimental impact on clinical outcomes, such as the length of hospital stay (<em>P</em> = 0.19). Our results proved robust to sensitivity analyses.</div></div><div><h3>Conclusion</h3><div>We offered reasonable evidence for using POCT to reduce antibiotic exposure for AECOPD without adversely affecting clinical outcomes. As diagnostic techniques become increasingly important in combating antimicrobial resistance, the use of POCT should be encouraged.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107889"},"PeriodicalIF":4.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The first reported case of monkeypox virus clade Ⅰb infection in china—clinical presentation and epidemiologic implications 中国首例猴痘病毒分支Ⅰb感染病例的临床表现和流行病学意义。
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-18 DOI: 10.1016/j.ijid.2025.107881
Weizhe Pan , Rui Ge , Guoying Zhu , Yangyang Tian , Yong Yan , Xiaofei Fu , Wei Jiang , Dongfang Zhong , Zhongwen Chen
{"title":"The first reported case of monkeypox virus clade Ⅰb infection in china—clinical presentation and epidemiologic implications","authors":"Weizhe Pan ,&nbsp;Rui Ge ,&nbsp;Guoying Zhu ,&nbsp;Yangyang Tian ,&nbsp;Yong Yan ,&nbsp;Xiaofei Fu ,&nbsp;Wei Jiang ,&nbsp;Dongfang Zhong ,&nbsp;Zhongwen Chen","doi":"10.1016/j.ijid.2025.107881","DOIUrl":"10.1016/j.ijid.2025.107881","url":null,"abstract":"<div><div>Recently, Monkeypox Virus (MPXV) clade Ib has caused serious health hazards in several countries. Herein, we report the first case of a clade Ib MPXV infection in China. MPXV was detected in a 28-year-old female on January 2, 2025. Whole-genome sequencing analysis revealed the strain to be clade Ib. The case presented with headache and disseminated rashes, with symptoms resolving symptomatic treatment and scabs shedding prior to discharge. Epidemiological studies and laboratory tests suggested transmission through close contact with a man who recently came from the Democratic Republic of Congo. Significantly, although some environmental samples tested positive, all contacts reminded negative, indicating that absence of secondary transmission. Furthermore, the clinical presentation of this case showed different manifestations from clade IIb MPXV infections. Epidemiological patterns also suggested sexual transmission served as the predominant route for clade Ib MPXV spread. These findings provide critical insights to enhance early detection strategies and inform targeted intervention measures aimed at curbing disease progression while mitigating risks of wider community spread.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107881"},"PeriodicalIF":4.8,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
World TB Day 2025 Theme “Yes! We Can End TB: Commit, Invest, Deliver” can be made a reality through concerted global efforts to advance diagnosis, treatment and research of tuberculosis infection and disease 2025年世界防治结核病日主题:“是的!通过协调一致的全球努力,推进结核病感染和疾病的诊断、治疗和研究,我们可以实现“终结结核病:承诺、投资、实施”。
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-17 DOI: 10.1016/j.ijid.2025.107892
Delia Goletti , Alberto Matteelli , Jacqueline M. Cliff , Graeme Meintjes , Steve Graham , Hanif Esmail , Shui Shan Lee
{"title":"World TB Day 2025 Theme “Yes! We Can End TB: Commit, Invest, Deliver” can be made a reality through concerted global efforts to advance diagnosis, treatment and research of tuberculosis infection and disease","authors":"Delia Goletti ,&nbsp;Alberto Matteelli ,&nbsp;Jacqueline M. Cliff ,&nbsp;Graeme Meintjes ,&nbsp;Steve Graham ,&nbsp;Hanif Esmail ,&nbsp;Shui Shan Lee","doi":"10.1016/j.ijid.2025.107892","DOIUrl":"10.1016/j.ijid.2025.107892","url":null,"abstract":"","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107892"},"PeriodicalIF":4.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of HIV-1 transmission clusters and transmitted drug resistance in men who have sex with men: A multicenter study in Portugal (2014-2019) 艾滋病毒-1传播集群和男男性行为者传播耐药性的决定因素:葡萄牙的一项多中心研究(2014-2019)
IF 4.8 2区 医学
International Journal of Infectious Diseases Pub Date : 2025-03-17 DOI: 10.1016/j.ijid.2025.107888
Ricardo Abrantes , Victor Pimentel , Cruz Sebastião , Mafalda N.S. Miranda , Sofia Seabra , Ana Rita Silva , António Diniz , Bianca Ascenção , Carmela Piñeiro , Carmo Koch , Catarina Rodrigues , Cátia Caldas , Célia Morais , Domitília Faria , Elisabete Gomes da Silva , Eugénio Teófilo , Fátima Monteiro , Fausto Roxo , Fernando Maltez , Fernando Rodrigues , Ana B. Abecasis
{"title":"Determinants of HIV-1 transmission clusters and transmitted drug resistance in men who have sex with men: A multicenter study in Portugal (2014-2019)","authors":"Ricardo Abrantes ,&nbsp;Victor Pimentel ,&nbsp;Cruz Sebastião ,&nbsp;Mafalda N.S. Miranda ,&nbsp;Sofia Seabra ,&nbsp;Ana Rita Silva ,&nbsp;António Diniz ,&nbsp;Bianca Ascenção ,&nbsp;Carmela Piñeiro ,&nbsp;Carmo Koch ,&nbsp;Catarina Rodrigues ,&nbsp;Cátia Caldas ,&nbsp;Célia Morais ,&nbsp;Domitília Faria ,&nbsp;Elisabete Gomes da Silva ,&nbsp;Eugénio Teófilo ,&nbsp;Fátima Monteiro ,&nbsp;Fausto Roxo ,&nbsp;Fernando Maltez ,&nbsp;Fernando Rodrigues ,&nbsp;Ana B. Abecasis","doi":"10.1016/j.ijid.2025.107888","DOIUrl":"10.1016/j.ijid.2025.107888","url":null,"abstract":"<div><h3>Introduction</h3><div>In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determinants in MSM newly diagnosed in Portugal between 2014 and 2019.</div></div><div><h3>Methods</h3><div>A total of 340 MSM newly diagnosed with HIV-1 infection at 17 hospitals in Portugal were included. TC was identified with branch support ≥90% and 1.5% genetic distance. Logistic regression models were used to examine factors associated with TC and TDR.</div></div><div><h3>Results</h3><div>We identified 38 TC with 104 MSM, which includes 81 (26.6%) of the 305 MSM from our sample included in cluster analysis. The overall prevalence of TDR was 8.2%. Only HIV-1 subtype C was significantly associated with TDR. Overall, 10.5% of the clusters had at least 1 surveillance drug resistance mutation. There was no significant difference in the prevalence of TDR or the proportion of Portuguese and migrant MSM inside and outside clusters. Age at diagnosis, district of residence, unprotected sex with a woman, HIV testing, presenter status, and HIV-1 subtype were significantly associated with TC.</div></div><div><h3>Conclusion</h3><div>Specific subgroups of MSM are contributing to HIV-1 clustered transmission in Portugal. However, no association was found between TDR and sociodemographic or behavioral factors. Directed prevention measures should focus on those subgroups.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"155 ","pages":"Article 107888"},"PeriodicalIF":4.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信