International Journal of Infectious Diseases最新文献

{"title":"Acute generalized exanthematous pustulosis associated with human parvovirus B19 infection","authors":"Juliette Coursier , Aymeric Hennemann , Léa Malinowski , Quentin Lepiller , Joséphine Moreau , François Aubin","doi":"10.1016/j.ijid.2025.107935","DOIUrl":"10.1016/j.ijid.2025.107935","url":null,"abstract":"","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"157 ","pages":"Article 107935"},"PeriodicalIF":4.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and genetic diversity of common human coronaviruses in Beijing, 2015-2023: A prospective multicenter study","authors":"Qi Huang ,&nbsp;Lu Kang ,&nbsp;Xiaofeng Wei ,&nbsp;Cheng Gong ,&nbsp;Hui Xie ,&nbsp;Maozhong Li ,&nbsp;Yiting Wang ,&nbsp;Mei Dong ,&nbsp;Fang Huang","doi":"10.1016/j.ijid.2025.107926","DOIUrl":"10.1016/j.ijid.2025.107926","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the epidemiological and genetic features of common human coronaviruses (HCoVs) in Beijing in the context of the COVID-19 pandemic.</div></div><div><h3>Methods</h3><div>We collected clinical samples from patients with acute respiratory tract infections (ARTIs) in 35 sentinel hospitals from 2015 to 2023. HCoVs were detected via multiple real-time PCR, and S gene sequencing and phylogenetic analysis were subsequently performed.</div></div><div><h3>Results</h3><div>From 2015 to 2023, the combined detection rate of HCoVs was 1.55% (909/58,550). During the COVID-19 pandemic, a significant increase in HCoVs detection was observed (<em>P</em> &lt; 0.001). Overall, the epidemic season of four HCoVs was from July to October, and each HCoV showed different epidemic seasons. Notably, HCoV-NL63 and HCoV-229E exhibited pronounced annual alternations in prevalence. The highest combined detection rates of HCoVs were in the ≥60 years age group (1.85%), followed by the 0-5 years age group (1.48%). HCoV-229E was more prevalent in patients with severe community-acquired pneumonia (sCAP) (<em>P</em> = 0.001). Phylogenetic analyses revealed that the four HCoVs were subjected to negative selection pressure, and multiple high-frequency amino acid site mutations were observed. HCoV-229E formed an emerging lineage after 2021.</div></div><div><h3>Conclusions</h3><div>This nine-year multicenter study in Beijing systematically elucidated that the four HCoVs exhibit distinct epidemiological characteristics, susceptible populations, and common mutations in amino acid sites, especially in the context of COVID-19. Therefore, continuous epidemiological surveillance and genetic characterization studies are imperative for predictive warning and timely identification of emerging coronavirus.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"158 ","pages":"Article 107926"},"PeriodicalIF":4.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concerns about statistical analyses in the study on polymyxin B treatment of carbapenem-resistant gram-negative bacilli infections: authors' reply.","authors":"Simin Zhou, Weihong Ge","doi":"10.1016/j.ijid.2025.107937","DOIUrl":"10.1016/j.ijid.2025.107937","url":null,"abstract":"","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":" ","pages":"107937"},"PeriodicalIF":4.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating troubled waters: a systematic review of prosthetic valve endocarditis reported cases treated with suppressive antimicrobial treatment","authors":"Pietro Valsecchi ,&nbsp;Matteo Calia ,&nbsp;Paola Giordani ,&nbsp;Cecilia Giuliani ,&nbsp;Alessia Arcuri ,&nbsp;Valeria Scotti ,&nbsp;Elena Seminari ,&nbsp;Raffaele Bruno","doi":"10.1016/j.ijid.2025.107934","DOIUrl":"10.1016/j.ijid.2025.107934","url":null,"abstract":"<div><h3>Objectives</h3><div>We aimed to characterize suppressive antimicrobial treatment (SAT) for non-surgical candidate patients with prosthetic valve endocarditis (PVE).</div></div><div><h3>Methods</h3><div>We systematically reviewed PubMed and Embase databases for studies reporting individual data on patients with PVE medically treated for longer than 8 weeks published until the 31^st of June 2024. The review protocol was registered on PROSPERO database [CRD42024529650].</div></div><div><h3>Results</h3><div>One hundred seventy patients were retrieved from 91 studies. PVE-related death during follow-up occurred in 26 (15.57%) patients, being associated with coagulase-negative staphylococci PVE in multivariate Cox regression model (HR 3.40, 95% CI 1.06-10.97, <em>P</em>-value = 0.04). Relapse occurred in 15 (8.92%) patients and was similar according to SAT discontinuation (long-rank test <em>P</em>-value = 0.8). This was confirmed after performing landmark analysis to adjust for survival bias (HR 0.97; 95% CI 0.21-4.4, <em>P</em>-value = 0.98). SAT-related adverse events were reported in 15% of the patients.</div></div><div><h3>Conclusion</h3><div>Supporting evidence for SAT is low and derived from case reports and case series. SAT seems well tolerated, but clinical effectiveness should be further evaluated due to the relevant mortality rate. In selected cases when SAT discontinuation is considered, close and long-term follow-up is crucial to prevent relapse.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"158 ","pages":"Article 107934"},"PeriodicalIF":4.8,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Prospective Pilot Clinical Study reveals a promising non-toxic anti-biofilm activity of gentamicin-EDTA-Na₂ Central Venous Catheter Lock Solution","authors":"David Lebeaux ,&nbsp;Bérénice Souhail ,&nbsp;Tan-Phuc Bui-Van ,&nbsp;Lénaig Le-Fouler ,&nbsp;Matthieu Lafaurie ,&nbsp;Raphael Lepeule ,&nbsp;Etienne Canoui ,&nbsp;Victoire de Lastours ,&nbsp;Antoine Froissart ,&nbsp;Damien Blez ,&nbsp;Christophe Beloin ,&nbsp;Jean-Marc Ghigo ,&nbsp;Fabrice Pirot ,&nbsp;Carole Dhelens ,&nbsp;Sandrine Fernandes-Pellerin","doi":"10.1016/j.ijid.2025.107933","DOIUrl":"10.1016/j.ijid.2025.107933","url":null,"abstract":"<div><h3>Objectives</h3><div>The treatment of long-term intravenous catheter-related bloodstream infections (LTIVC-related BSI) often requires catheter removal or conservative treatment using intra-catheter locks, with a 50–60% success rate. We previously demonstrated the synergistic effect of a combination of gentamicin and ethylenediaminetetraacetic acid disodium salt (EDTA-Na₂) against bacterial biofilms. We conducted a phase 1/2 clinical trial to assess the tolerance and efficacy of genta-EDTA-Na₂ locks for the conservative treatment of LTIVC-related BSI.</div></div><div><h3>Methods</h3><div>Prospective study including adult patients with monomicrobial, uncomplicated LTIVC-related BSI caused by gentamicin-susceptible coagulase-negative staphylococci, <em>Enterobacterales,</em> or <em>Pseudomonas aeruginosa</em>. Primary objective: assess the safety and efficacy at genta-EDTA-Na₂ locks at day 40 (D40) by evaluating the frequency of clinical and microbiological cure 30 days after the end of treatment (D40).</div></div><div><h3>Results</h3><div>Eight patients were included. Complete follow-up was obtained for seven patients, six of whom met the criteria for cure. The single patient with incomplete follow-up met all criteria for cure at D23. A single microbiological failure occurred (relapse of <em>P. aeruginosa</em> LTIVC-related BSI). Two patients experienced at least one serious adverse event; none were attributed to the genta-EDTA-Na₂ locks.</div></div><div><h3>Conclusions</h3><div>Genta-EDTA-Na₂, used as intra-catheter locks, may be a promising anti-biofilm candidate for evaluation in a randomized controlled trial.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"157 ","pages":"Article 107933"},"PeriodicalIF":4.8,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in nontuberculous mycobacterial disease mortality based on 2000-2022 data from 83 countries","authors":"Ko Harada ,&nbsp;Quynh Thi Vu ,&nbsp;Yoshito Nishimura ,&nbsp;Tatsuaki Takeda ,&nbsp;Hirofumi Hamano ,&nbsp;Yusuke Minato ,&nbsp;Yoshito Zamami ,&nbsp;Toshihiro Koyama ,&nbsp;Hideharu Hagiya","doi":"10.1016/j.ijid.2025.107932","DOIUrl":"10.1016/j.ijid.2025.107932","url":null,"abstract":"<div><h3>Objectives</h3><div>To examine the international trends for nontuberculous mycobacterial-associated mortality rates, as nontuberculous mycobacterial infections are becoming increasingly prevalent and pose a significant public health challenge, especially in older populations.</div></div><div><h3>Methods</h3><div>This retrospective observational study used data from the World Health Organization mortality database, which included patients with nontuberculous mycobacterial infection in 83 countries. We stratified the data by sex, age, and geographic region and calculated crude and age-standardized mortality rates to estimate long-term mortality trends.</div></div><div><h3>Results</h3><div>In total, 42,182 nontuberculous mycobacterial infection-associated deaths (58.1% in women) were reported in 83 countries between 2000 and 2022. The locally weighted regression model estimation for the nontuberculous mycobacterial infection-associated mortality rate more than doubled—from 0.36 deaths per 1000,000 individuals in 2000 to 0.77 deaths per 1000,000 individuals in 2022. Eighty-six percent of nontuberculous mycobacterial infection-associated deaths occurred in people aged ≥65 years. The mortality rate was the highest in the Western Pacific Region.</div></div><div><h3>Conclusion</h3><div>This study highlights the impact of emerging nontuberculous mycobacterial diseases and the importance of targeted interventions for managing and reducing mortality, particularly in vulnerable older populations. Further studies are warranted to determine the factors contributing to geographical disparity and treatment options.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"158 ","pages":"Article 107932"},"PeriodicalIF":4.8,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First report of a fatal case of Clostridium porci bacteremia in an 8-month-old girl presenting with purpura fulminans associated with concurrent Yersinia pseudotuberculosis infection","authors":"Tetsuro Oku ,&nbsp;Kenichi Tetsuhara ,&nbsp;Akihiko Tamaki ,&nbsp;Sho Akamine ,&nbsp;Yoshitaka Tomita ,&nbsp;Rie Kikuno ,&nbsp;Mitsumasa Saito ,&nbsp;Takayuki Hoshina","doi":"10.1016/j.ijid.2025.107931","DOIUrl":"10.1016/j.ijid.2025.107931","url":null,"abstract":"<div><h3>Objectives</h3><div><em>Yersinia pseudotuberculosis</em> rarely causes bacteremia, and <em>Clostridium porci</em>, an obligate anaerobic bacterium identified as part of the intestinal microbiota in pigs, has not been reported to cause human infection. We report an infant with VACTERL association who developed purpura fulminans. Upon transfer to our hospital, the patient went into shock. Laboratory findings revealed elevated inflammatory markers (white blood cell count of 25.3 × 10⁹/L and serum C-reactive protein level of 4.02 mg/dL), coagulopathy suggestive of disseminated intravascular coagulation (prothrombin time-international normalized ratio of 1.38 and plasma D-dimer level of 7.4 µg/dL), and decreased plasma protein C activity (28%). Despite the intensive care, the patient died 55 h after admission.</div></div><div><h3>Methods</h3><div>Gram-positive and Gram-negative bacilli were isolated from blood samples and bacterial 16S rRNA gene sequencing was performed.</div></div><div><h3>Results</h3><div>Bacterial 16S rRNA gene sequencing identified as C. porci and <em>Y. pseudotuberculosi</em>.</div></div><div><h3>Conclusions</h3><div><em>Y. pseudotuberculosis</em> rarely causes bacteremia and C. porci infection in humans is reported for the first time. Since <em>Y. pseudotuberculosis</em> can cause bacteremia, the bacteria should be cultured under conditions that allow <em>Y. pseudotuberculosis</em> to grow when patients with gastrointestinal diseases go into shock. In addition, a detailed analysis of C. porci, including its pathogenicity, is necessary because it can cause severe infections.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"157 ","pages":"Article 107931"},"PeriodicalIF":4.8,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-hospital mortality among children and adults hospitalized with COVID-19 in Africa across pre-delta, delta, and omicron SARS-CoV-2 waves","authors":"Seth Inzaule ,&nbsp;Ronaldo Silva ,&nbsp;Soe Soe Thwin ,&nbsp;Jassat Waasila ,&nbsp;Alimuddin Zumla ,&nbsp;Jamie Rylance ,&nbsp;John Appiah ,&nbsp;Janet Diaz ,&nbsp;Silvia Bertagnolio","doi":"10.1016/j.ijid.2025.107924","DOIUrl":"10.1016/j.ijid.2025.107924","url":null,"abstract":"<div><h3>Background</h3><div>This study examines in-hospital mortality among children and adults hospitalized with COVID-19 across the pre-Delta, Delta, and Omicron waves in the African region.</div></div><div><h3>Method</h3><div>We conducted a retrospective cohort study using individual-level data from 520,810 hospitalized children and adults in 13 African countries. Cox proportional hazards regression models were used to assess the impact of SARS-CoV-2 variants on in-hospital mortality.</div></div><div><h3>Findings</h3><div>Among children, the risk of in-hospital mortality was comparable between pre-Delta and Delta waves (aHR 1.02, 95% CI 0.77-1.35). In adults, mortality increased by 6% during Delta wave compared with pre-Delta wave (aHR 1.06, 95% CI 1.04-1.09). During Omicron wave, mortality risk decreased significantly by 42% in children (aHR 0.58, 95% CI 0.43-0.80) and 59% in adults (aHR 0.41, 95% CI 0.40-0.43) compared to the Delta wave. Notably, the reduction in mortality risk during the Omicron wave was less pronounced for children with severe or critical COVID-19, those co-infected with HIV, and adults co-infected with either HIV or tuberculosis.</div></div><div><h3>Conclusion</h3><div>Despite a general reduction in mortality risk during Omicron wave, persistently high mortality in specific high-risk groups underscores the importance of prioritizing booster vaccinations and intensified treatment for vulnerable populations as per WHO recommendations.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"157 ","pages":"Article 107924"},"PeriodicalIF":4.8,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiology and long-term outcomes in community-acquired, nosocomial and post-neurosurgical meningitis with positive bacterial culture in Ontario, Canada: A population-based cohort study","authors":"Anthony D Bai ,&nbsp;J. Gordon Boyd ,&nbsp;Wenbin Li ,&nbsp;Robert J. Campbell ,&nbsp;Sudeep S. Gill","doi":"10.1016/j.ijid.2025.107925","DOIUrl":"10.1016/j.ijid.2025.107925","url":null,"abstract":"<div><h3>Background</h3><div>Bacterial meningitis is a rare but severe infection that has a high risk of mortality and morbidity. The study objective was to describe the microbiology, long-term mortality risk, and complications from neurologic sequelae for bacterial meningitis.</div></div><div><h3>Methods</h3><div>This retrospective cohort study included adults with a positive cerebrospinal fluid (CSF) bacterial culture collected from 2014 to 2022 inclusive in Ontario, Canada. Patients were followed for 1 year. The primary outcome was all-cause mortality. Secondary outcomes included aspiration, enteral feeding tube insertion, decubitus ulcers, falls and/or fractures, and long-term care admissions.</div></div><div><h3>Results</h3><div>856(2.1%) patients had positive CSF cultures including 431(50.4%) community-acquired, 255 (29.8%) nosocomial and 170(19.9%) post-neurosurgical meningitis cases. <em>Staphylococcus aureus</em> was the second most common pathogen in community-acquired meningitis (10.9%) and the most common pathogen in nosocomial (11.8%) and post-neurosurgical (22.9%) meningitis. All-cause mortality at 30, 90, 180, and 365 days were 11.4%, 13.2%, 14.8% and 16.5% for community-acquired meningitis; 16.5%, 22.4%, 25.1% and 27.1% for nosocomial meningitis; and 10.6%, 20.0%, 25.9% and 28.8% for postneurosurgical meningitis. Enteral feeding tube was inserted in 2.8%, 15.3%, and 20.0% of community-acquired, nosocomial, and post-neurosurgical meningitis cases respectively. Other secondary outcomes occurred rarely.</div></div><div><h3>Conclusion</h3><div><em>S. aureus</em> was an important pathogen. Meningitis mortality continued to increase over 1 year. For nosocomial and post-neurosurgical meningitis, one in four died by 1 year and many required enteral feeding tube.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"157 ","pages":"Article 107925"},"PeriodicalIF":4.8,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning for personalized risk assessment of HIV, syphilis, gonorrhoea and chlamydia: A systematic review and meta-analysis","authors":"Phyu M. Latt ,&nbsp;Nyi N. Soe ,&nbsp;Christopher K. Fairley ,&nbsp;Eric P.  F. Chow ,&nbsp;Cheryl C. Johnson ,&nbsp;Purvi Shah ,&nbsp;Ismail Maatouk ,&nbsp;Lei Zhang ,&nbsp;Jason J. Ong","doi":"10.1016/j.ijid.2025.107922","DOIUrl":"10.1016/j.ijid.2025.107922","url":null,"abstract":"<div><h3>Background</h3><div>Machine learning (ML) shows promise for sexually transmitted infection (STI) risk prediction, but systematic evidence of its effectiveness remains fragmented.</div></div><div><h3>Methods</h3><div>We systematically searched six electronic databases, three preprint archives and conference proceedings (January 2010-April 2024). Studies reporting quantitative performance metrics for supervised ML-based STI risk prediction models were included. We used a bivariate random-effects model to estimate pooled sensitivity, specificity and area under the curve (AUC). The risk of bias was assessed using the Prediction model Risk of Bias Assessment Tool. We conducted sequential analyses of studies with complete and reconstructed confusion matrices. Subgroup analyses and meta-regression explored potential sources of heterogeneity.</div></div><div><h3>Results</h3><div>Among 3877 records screened, 25 studies comprising 45 unique models met inclusion criteria. For HIV, analysis of studies with complete confusion matrices (7 studies, 9 contingency tables) demonstrated summary AUC of 0.91 (95% CI: 0.88-0.93), pooled sensitivity 0.84 (0.76-0.90) and specificity 0.84 (0.70-0.93). Substantial heterogeneity persisted across subgroups (<em>I</em>² &gt; 98%). For other STIs, individual studies reported AUCs ranging from 0.75-0.87 for syphilis (<em>n</em> = 5), 0.73-1.00 for gonorrhoea (<em>n</em> = 6) and 0.67-1.00 for chlamydia (<em>n</em> = 6).</div></div><div><h3>Discussion</h3><div>While ML models show promising performance, particularly for HIV, significant heterogeneity complicates interpretation. Future research should prioritize external validation, standardized guidelines and multi-centred robust implementation studies to evaluate clinical impact.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"157 ","pages":"Article 107922"},"PeriodicalIF":4.8,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}