The Predictive Value of Pulmonary Consolidation combined with BNP for Cardiovascular Events in Children with RSV Infection.

Background: The cardiovascular impact of Respiratory syncytial virus infection has surpassed its effects on the respiratory system. This study aims to identify independent risk factors for these events.

Methods: This study is a single-center, retrospective analysis of 105 pediatric patients with RSV infection. The patients were divided into two groups: those with cardiovascular events and those without. Logistic regression analyses were conducted to identify independent risk factors for cardiovascular events in children with RSV infection. The predictive value of these factors for cardiovascular events in RSV-infected children was evaluated using the area under the curve.

Results: Compared to the group without cardiovascular events, the group with cardiovascular events showed significantly higher levels of NLR, BNP, BUN, D-dimer, and required higher scores for vasopressor use, higher oxygen concentrations, and a higher proportion of respiratory support. And had longer PICU stays and higher hospitalization costs. Logistic analyses identified pulmonary consolidationand BNP as independent risk factors for cardiovascular events in RSV-infected children. When pulmonary consolidation and BNP were used in combination for prediction, the AUC increased to 0.858.

Conclusion: The combination of pulmonary consolidation and BNP has a higher predictive value for the occurrence of cardiovascular events in children with RSV infection.