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All optical four bit two's complement generator and single bit comparator using reflective semiconductor optical amplifier 采用反射式半导体光放大器的全光学四位二进制补码发生器和单比特比较器
International Journal of Nano and Biomaterials Pub Date : 2020-05-26 DOI: 10.1504/ijnbm.2020.10029635
K. Mukherjee, K. Maji, Ashif Raja
{"title":"All optical four bit two's complement generator and single bit comparator using reflective semiconductor optical amplifier","authors":"K. Mukherjee, K. Maji, Ashif Raja","doi":"10.1504/ijnbm.2020.10029635","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10029635","url":null,"abstract":"All optical two's complement generator for four bit binary numbers and single bit comparator is proposed and analysed using reflective semiconductor optical amplifier (RSOA). We use Soliton bits to implement the device and therefore, find application in long distance communication systems. The performance is analysed in terms of input-output bit patterns, quality factor, pseudo eye diagram, relative eye opening and amplified spontaneous emission characteristics.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46260911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Polysaccharide capped antibacterial silver nanoparticles synthesis using green chemistry 多糖包封抗菌纳米银的绿色化学合成
International Journal of Nano and Biomaterials Pub Date : 2020-05-26 DOI: 10.1504/ijnbm.2020.10029637
J. Sarkar, Gajendra Nath Maity, Somanjana Khatua, Soumitra Mondal, K. Acharya
{"title":"Polysaccharide capped antibacterial silver nanoparticles synthesis using green chemistry","authors":"J. Sarkar, Gajendra Nath Maity, Somanjana Khatua, Soumitra Mondal, K. Acharya","doi":"10.1504/ijnbm.2020.10029637","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10029637","url":null,"abstract":"Advancement of an environment friendly, trustworthy, and speedy route for the production of Ag-NP using natural system is an essential urge in nanotechnology. Biological synthetic techniques are considered as a better alternative over other conventional methods. Silver is a safe inorganic element that is projected as 'next-gen' antimicrobial agent and had been extensively used against several bacterial strains from the ancient times. Here, we document a low-cost green synthesis approach for construction of Ag-NP using fruit extracted polysaccharide of Bruguiera cylindrica, a mangrove plant of Sundarban. During the investigation of GC-MS an adequate amount of glucose was found as major carbohydrate molecule in the extracted polysaccharide. Synthesised Ag-NP were also characteristically described by UV-Vis, DLS, TEM, EDAX, XRD and FTIR. The average diameter of the Ag-NP was 4.5 ± 1 nm. Additionally, antibacterial nature of Ag-NP was also find out against some of the pathogenic gram-positive and gram-negative bacteria.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46535926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biogenic nanosilver inhibits Mycobacteria using nitrate reductase assay 利用硝酸还原酶测定生物源纳米银抑制分枝杆菌
International Journal of Nano and Biomaterials Pub Date : 2019-08-23 DOI: 10.1504/IJNBM.2019.10023327
Adebayo J. Bello, L. Adams, N. Onyejepu, Justice I. Igbinehi, Omoboyede F. Igbari, J. Okpuzor
{"title":"Biogenic nanosilver inhibits Mycobacteria using nitrate reductase assay","authors":"Adebayo J. Bello, L. Adams, N. Onyejepu, Justice I. Igbinehi, Omoboyede F. Igbari, J. Okpuzor","doi":"10.1504/IJNBM.2019.10023327","DOIUrl":"https://doi.org/10.1504/IJNBM.2019.10023327","url":null,"abstract":"Nanosilver was synthesised by bioreduction using aqueous extracts of Moringa oleifera (MO-AgNPs) leaf and Allium cepa bulb (AC-AgNPs) as reducing and capping agents. The nanosilver was characterised with UV/vis, FT-IR, and SEM-EDX. Microbiological activity on five Mycobacteria strains: ATCC 35882, ATCC 25177, Mycobacterium other than tuberculosis (MOTT), Mycobacterium fortuitum and multi drug resistance M. tuberculosis (MDR-MTB) was investigated using nitrate reductase assay (NRA). Results obtained for UV/vis gave absorption maxima at 430 nm for MO-AgNPs and 440 nm for AC-AgNPs. FT-IR showed functional groups associated with the biomolecular capping agents. SEM showed the nanosilver formed aggregates spherical and/or in oval shape with smooth surface. EDX spectra exhibited the presence of elemental silver. Minimum inhibitory concentration (MIC) study for both nanosilver against Mycobacteria indicated a higher inhibitory activity for MO-AgNPs over the AC-AgNPs. Herein, we have reported the first biosynthesised nanosilver activity against Mycobacteria using NRA. Nanosilver may therefore be developed as nanoaerosol for targeted and effective treatment of Mycobacteria infections.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45033311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and evaluation of regenerated cellulose and fibrin biocomposite impregnated with silver nanoparticles as a wound dressing material 纳米银浸渍再生纤维素和纤维蛋白生物复合材料的合成与评价
International Journal of Nano and Biomaterials Pub Date : 2019-08-19 DOI: 10.1504/IJNBM.2019.10023328
I. N. Ahamed, P. M. Kashif, S. Sankar, T. Sastry
{"title":"Synthesis and evaluation of regenerated cellulose and fibrin biocomposite impregnated with silver nanoparticles as a wound dressing material","authors":"I. N. Ahamed, P. M. Kashif, S. Sankar, T. Sastry","doi":"10.1504/IJNBM.2019.10023328","DOIUrl":"https://doi.org/10.1504/IJNBM.2019.10023328","url":null,"abstract":"In the present study, a composite wound dressing material containing fibrin (F) and regenerated cellulose (RC) impregnated with silver nanoparticles (Ag) with and without antibiotic gentamicin (G) were primed. The biocomposites prepared were characterised for their physicochemical investigation using conventional techniques. The results obtained showed that with the increase of fibrin level in the complex results in a reduction in its water absorption ability. The FTIR and SEM studies have shown the composite nature of the biocomposites prepared. RC-F-Ag and RC-F-Ag-G composites were used as wound dressing materials on experimental wounds of rats. The healing pattern of the wounds was evaluated by planimetric studies, macroscopic observations and biochemical studies. The results have shown faster healing patterns in the wounds treated with RC-F-Ag and RC-F-Ag-G composites compared to untreated controls. This study suggests RC-F-Ag biocomposite may be a potential candidate as a wound dressing material and may be tried on the clinical wounds of animals before being applied on humans.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41976210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyaluronic acid carrier-cell interactions: a tri-culture model of the tumour microenvironment to study siRNA delivery under flow conditions 透明质酸载体-细胞相互作用：肿瘤微环境的三种培养模型，用于研究流动条件下siRNA的递送
International Journal of Nano and Biomaterials Pub Date : 2019-08-19 DOI: 10.1504/IJNBM.2019.10023325
J. Rosa, N. Tirelli, A. Tirella
{"title":"Hyaluronic acid carrier-cell interactions: a tri-culture model of the tumour microenvironment to study siRNA delivery under flow conditions","authors":"J. Rosa, N. Tirelli, A. Tirella","doi":"10.1504/IJNBM.2019.10023325","DOIUrl":"https://doi.org/10.1504/IJNBM.2019.10023325","url":null,"abstract":"CD44 is often over expressed in solid tumours, rendering this protein a 'hot' target in drug delivery. As CD44 is the main surface receptor of hyaluronic acid (HA), one of the most common therapeutic approaches consists of hijacking the cell's mechanism of HA endocytosis to deliver active principles. This approach, however, presents two caveats: the poor understanding of HA-cell interactions and the ubiquitous expression of CD44 in other cell types, e.g., stromal cells. To predict the interaction of HA-decorated nanocarriers with CD44-expressing cells in the multi-cellular and complex tumour microenvironment, we have established a tri-culture, non-contact in vitro model (PANC-1 tumoural cells, HDF stromal cells, THP-1 macrophages) and quantified the delivery and kinetics of nanoparticle internalisation (via flow cytometry), investigating the system in both static and dynamic culturing conditions. We report that HA-decorated nanocarriers are able to preferentially deliver siRNA to pancreatic cancer cells, interestingly even under flow/dynamic conditions.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48102900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrospinning production of PVA/CS/HEMA/nHA bionanocomposite 静电纺丝制备PVA/CS/HEMA/nHA生物纳米复合材料
International Journal of Nano and Biomaterials Pub Date : 2019-08-19 DOI: 10.1504/IJNBM.2019.10023324
A. M. Salgado-Delgado, H. Hernández-Cocoletzi, E. Rubio-Rosas, A. Escobedo-Morales, E. Chigo-Anota, A. Olarte-Paredes, R. Salgado-Delgado, M. Trejo-Durán, V. Castaño
{"title":"Electrospinning production of PVA/CS/HEMA/nHA bionanocomposite","authors":"A. M. Salgado-Delgado, H. Hernández-Cocoletzi, E. Rubio-Rosas, A. Escobedo-Morales, E. Chigo-Anota, A. Olarte-Paredes, R. Salgado-Delgado, M. Trejo-Durán, V. Castaño","doi":"10.1504/IJNBM.2019.10023324","DOIUrl":"https://doi.org/10.1504/IJNBM.2019.10023324","url":null,"abstract":"PVA/CS/HEMA/nHA membranes were prepared by electrospinning at different voltages, to produce osteoinductive scaffolds that promote bone extracellular matrix production and in-situ remodelling. Infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) of samples obtained at 25 and 30 kV and 60 min spun reveal that the presence of chitosan generates some malformations, and glutaraldehyde generates agglomerations in the threads. FTIR do not show significant changes in the functional groups, which indicate that these PVA/CS/HEMA/nHA scaffolds may represent a promising biomaterial for bone tissue engineering.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44970328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Mechanosensitivity response of epithelial HT29 cells on titanium dioxide nanotube array surface via CK8 protein expression 二氧化钛纳米管阵列表面上皮HT29细胞通过CK8蛋白表达的机制敏感性反应
International Journal of Nano and Biomaterials Pub Date : 2019-08-19 DOI: 10.1504/IJNBM.2019.10023326
R. Mydin, S. Sreekantan, R. Hazan, Ekhlas Qaid Qazem, M. F. Wajidi
{"title":"Mechanosensitivity response of epithelial HT29 cells on titanium dioxide nanotube array surface via CK8 protein expression","authors":"R. Mydin, S. Sreekantan, R. Hazan, Ekhlas Qaid Qazem, M. F. Wajidi","doi":"10.1504/IJNBM.2019.10023326","DOIUrl":"https://doi.org/10.1504/IJNBM.2019.10023326","url":null,"abstract":"Titanium dioxide nanotube arrays (TNA) have been proposed as novel nanosurface modifications for biomaterial implants and nanomedicine applications. However, the molecular mechanisms of cell-TNA mechanosensitivity are poorly understood. Therefore, this study investigates the effect of cell-TNA mechanosensitivity activity via cytokeratin (CK) protein marker. Field emission scanning electron microscopy (FESEM) characterisation was conducted on TNA with epithelial HT29 cells. The CK protein marker was also analysed using immunofluorescent staining and immunoblotting techniques. FESEM results showed that cells grown on TNA exhibited enhanced cytoplasmic extension and spreading characteristics. Furthermore, the cell interaction with TNA nanosurface showed high CK8 expression, thereby indicating the clustering or aggregation of the cytoskeleton proteins. Findings suggested that epithelial HT29 cells on TNA nanotopography may involve cytoskeleton mechanosensitivity response for cellular adaptation activity.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44552115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Theoretical study of anisotropic tunnelling conductance in iron-based orbitally ordered superconductors 铁基轨道有序超导体各向异性隧穿电导的理论研究
International Journal of Nano and Biomaterials Pub Date : 2019-01-31 DOI: 10.1504/IJNBM.2019.10018707
S. Jena, S. Agarwalla, G. C. Rout
{"title":"Theoretical study of anisotropic tunnelling conductance in iron-based orbitally ordered superconductors","authors":"S. Jena, S. Agarwalla, G. C. Rout","doi":"10.1504/IJNBM.2019.10018707","DOIUrl":"https://doi.org/10.1504/IJNBM.2019.10018707","url":null,"abstract":"We address here the role of Jahn-Tellar (JT) distortion on the superconducting (SC) gap in iron-based superconductors taking into account of the first and second nearest-neighbour (NN) electron hoppings in the square lattice within one band model approach. The Green's functions are calculated by using Zubarev's Green's function technique. The temperature dependent superconducting gap and the lattice strain are calculated from the correlation functions of the corresponding Green's functions and are computed self-consistently. The temperature dependent gap equations show that the superconducting gap is enhanced with the decrease of second nearest-neighbour hopping accompanied by the suppression of lattice strain near the superconducting transition temperature. The second nearest hopping introduces asymmetry in the tunnelling conductance.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49314668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of self-assembled polygalacturonic acid-peptide composites and their interactions with mesenchymal stem cells for potential applications in tendon tissue engineering 自组装聚半乳糖醛酸-肽复合物及其与间充质干细胞的相互作用在肌腱组织工程中的潜在应用
International Journal of Nano and Biomaterials Pub Date : 2019-01-31 DOI: 10.1504/IJNBM.2019.10018706
Grant A. Knoll, Harrison T. Pajovich, Steven M. Romanelli, I. Banerjee
{"title":"Development of self-assembled polygalacturonic acid-peptide composites and their interactions with mesenchymal stem cells for potential applications in tendon tissue engineering","authors":"Grant A. Knoll, Harrison T. Pajovich, Steven M. Romanelli, I. Banerjee","doi":"10.1504/IJNBM.2019.10018706","DOIUrl":"https://doi.org/10.1504/IJNBM.2019.10018706","url":null,"abstract":"We have developed a new biomimetic scaffold for potential applications in tendon tissue engineering (TE). The scaffold template was synthesised by conjugating polygalacturonic acid with the dipeptide leucyl-leucine to mimic the leucine rich proteoglycans found in the extracellular matrix (ECM) of tenocytes. To the template, type I collagen and an elastin derived peptide were incorporated in order to form the final PG-Leu-Leu-Col-El scaffold. Results indicated the formation of gelatinous, fibrous scaffolds. DSC analysis showed phase changes that included crystallisation and thermal melting due to re-organisation of the scaffold components. Young's modulus was determined to be 832 ± 2 MPa. Rheology studies showed that the scaffold maintained a constant G´ / G˝ ratio over a wide range of angular frequency. Cell studies with bone marrow derived mesenchymal stem cells (BMSC) indicated that the scaffolds promoted cell proliferation and formed three dimensional cell-scaffold matrices. This newly developed scaffold may open new opportunities for tissue engineering applications.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44533504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The study of thermal properties of f-electron systems in the ferromagnetic state 铁磁状态下f电子系统热性质的研究
International Journal of Nano and Biomaterials Pub Date : 2019-01-31 DOI: 10.1504/IJNBM.2019.10018705
Asit Kumar Shadangi, G. C. Rout
{"title":"The study of thermal properties of f-electron systems in the ferromagnetic state","authors":"Asit Kumar Shadangi, G. C. Rout","doi":"10.1504/IJNBM.2019.10018705","DOIUrl":"https://doi.org/10.1504/IJNBM.2019.10018705","url":null,"abstract":"The rare earth and actinide series of compounds display anomalous physical properties below a characteristic low temperature with very high specific heat coefficient and high effective mass. Here we consider the periodic Anderson model with the repulsive electron-electron interaction within mean-field approximation leading to ferromagnetism in the system. We calculate conduction electron as well as f-electron Green's functions by using Zubarev's Green's function technique and calculate ferromagnetic magnetisation numerically and self consistently. The thermal properties like the temperature dependent entropy, specific heat coefficient and electronic specific heat are calculated from the electron free-energy of the f-electron system and are computed numerically. The specific heat coefficient displays high value in heavy fermion state of the system where the position of the f-electron level is away from the Fermi level with the lower strength of hybridisation between f and conduction electrons.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49533992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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