Electrospinning production of PVA/CS/HEMA/nHA bionanocomposite

Q4 Chemistry

International Journal of Nano and Biomaterials Pub Date : 2019-08-19 DOI:10.1504/IJNBM.2019.10023324

A. M. Salgado-Delgado, H. Hernández-Cocoletzi, E. Rubio-Rosas, A. Escobedo-Morales, E. Chigo-Anota, A. Olarte-Paredes, R. Salgado-Delgado, M. Trejo-Durán, V. Castaño

引用次数: 1

Abstract

PVA/CS/HEMA/nHA membranes were prepared by electrospinning at different voltages, to produce osteoinductive scaffolds that promote bone extracellular matrix production and in-situ remodelling. Infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) of samples obtained at 25 and 30 kV and 60 min spun reveal that the presence of chitosan generates some malformations, and glutaraldehyde generates agglomerations in the threads. FTIR do not show significant changes in the functional groups, which indicate that these PVA/CS/HEMA/nHA scaffolds may represent a promising biomaterial for bone tissue engineering.

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静电纺丝制备PVA/CS/HEMA/nHA生物纳米复合材料

采用不同电压下静电纺丝制备PVA/CS/HEMA/nHA膜，制备促进骨细胞外基质生成和原位重构的骨诱导支架。红外光谱(FTIR)和扫描电镜(SEM)分析表明，壳聚糖的存在使丝线产生了一些变形，戊二醛在丝线中产生了结块。FTIR结果显示，PVA/CS/HEMA/nHA支架在骨组织工程中具有较好的应用前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Nano and Biomaterials Chemistry-Physical and Theoretical Chemistry

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： In recent years, frontiers of research in engineering, science and technology have been driven by developments in nanomaterials, encompassing a diverse range of disciplines such as materials science, biomedical engineering, nanomedicine and biology, manufacturing technology, biotechnology, nanotechnology, and nanoelectronics. IJNBM provides an interdisciplinary vehicle covering these fields. Advanced materials inspired by biological systems and processes are likely to influence the development of novel technologies for a wide variety of applications from vaccines to artificial tissues and organs to quantum computers. Topics covered include Nanostructured materials/surfaces/interfaces Synthesis of nanostructures Biological/biomedical materials Artificial organs/tissues Tissue engineering Bioengineering materials Medical devices Functional/structural nanomaterials Carbon-based materials Nanomaterials characterisation Novel applications of nanomaterials Modelling of behaviour of nanomaterials Nanomaterials for biomedical applications Biological response to nanomaterials.