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Synthesis and Characterization of Iron oxide Nanoparticles with Thymoquinone. 含百里醌氧化铁纳米颗粒的合成与表征。
International Journal of Nano and Biomaterials Pub Date : 2023-01-01 DOI: 10.1504/ijnbm.2023.10058901
Seema Tharannum, Tarun M, Sheshadri S. Temkar, Dinesh M. S
{"title":"Synthesis and Characterization of Iron oxide Nanoparticles with Thymoquinone.","authors":"Seema Tharannum, Tarun M, Sheshadri S. Temkar, Dinesh M. S","doi":"10.1504/ijnbm.2023.10058901","DOIUrl":"https://doi.org/10.1504/ijnbm.2023.10058901","url":null,"abstract":"Nigella sativa is a medicinal plant used for its antimicrobial properties. Thymoquinone (TQ) being the lead component of this plant seeds, exerts antibacterial, antifungal and antioxidant activity. It has also shown promising activity against cancer and inflammation through different modes of action. In recent developments for new applications in the field of medicine, nanotechnology has excelled as a very prominent and important field. Nanoparticles are generally in the dimension range of 1–100 nm. Iron oxide nanoparticles show enhanced antibacterial activity against gram-negative bacteria. The current research focuses on comparing the yield, stability and purity of thymoquinone synthesised iron oxide nanoparticles using different organic solvents, the benefits expressed by thymoquinone as a herbal drug and a novel approach to green synthesis of iron oxide nanoparticles with thymoquinone and testing for their stability, size and functional groups.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134892654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymeric bio-nanocomposite in biomedical field: a review on current status and challenges 高分子生物纳米复合材料在生物医学领域的研究现状与挑战
International Journal of Nano and Biomaterials Pub Date : 2023-01-01 DOI: 10.1504/ijnbm.2023.10059325
DINESH PATEL, Sachin Kumar, Hari Om Sharma, Shiv Kumar
{"title":"Polymeric bio-nanocomposite in biomedical field: a review on current status and challenges","authors":"DINESH PATEL, Sachin Kumar, Hari Om Sharma, Shiv Kumar","doi":"10.1504/ijnbm.2023.10059325","DOIUrl":"https://doi.org/10.1504/ijnbm.2023.10059325","url":null,"abstract":"","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135649726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of carbon fibre layer with alumina and tri calcium phosphate on mechanical properties of denture base 氧化铝和磷酸三钙复合碳纤维层对义齿基托力学性能的影响
International Journal of Nano and Biomaterials Pub Date : 2021-04-29 DOI: 10.1504/ijnbm.2021.114691
Wafaa A. Hussain, Selma M. H. Al-Jawad, S. Hannon
{"title":"Effect of carbon fibre layer with alumina and tri calcium phosphate on mechanical properties of denture base","authors":"Wafaa A. Hussain, Selma M. H. Al-Jawad, S. Hannon","doi":"10.1504/ijnbm.2021.114691","DOIUrl":"https://doi.org/10.1504/ijnbm.2021.114691","url":null,"abstract":"In this study unreinforced and reinforced samples with uncoated and coated woven carbon fibres (WCF) with alumina (Al2O3) and tri calcium phosphate (TCP) powders were incorporated into heat polymerised polymethyl methacrylate (PMMA) denture base resin in addition to poly vinyl alcohol (PVA) with 0.02 and 0.09 weight fraction (wi). Impact, flexural strength and water absorption of layered denture base resin have been studied. Surface morphology of the coating layers has been examined by field emission-scanning electron microscope (FE-SEM) and the toxicity of reinforcing materials were also investigated in human blood cells. Uncoated WCF sample showed high impact and flexural strength, but it still exhibits poor aesthetic. A significant increase of the impact strength values was observed in the coated specimens, in expense of flexural strength. The effect of TCP on PMMA resin was higher than when using alumina particles. Aesthetic, impact and flexural strength have improved together when PVA increased.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48573319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Synthesis and characterisation of magnetic κ-carrageenan nanocomposites for chitinase33 enzyme immobilisation 几丁质酶33固定化磁性κ-卡拉胶纳米复合材料的合成与表征
International Journal of Nano and Biomaterials Pub Date : 2020-12-28 DOI: 10.1504/ijnbm.2020.10034543
R. Mohammadzadeh, Ahad Arazpour, A. Akbari
{"title":"Synthesis and characterisation of magnetic κ-carrageenan nanocomposites for chitinase33 enzyme immobilisation","authors":"R. Mohammadzadeh, Ahad Arazpour, A. Akbari","doi":"10.1504/ijnbm.2020.10034543","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10034543","url":null,"abstract":"Chitinases are chitin-degrading enzymes that have wide biotechnological applications in the fields of medicine, agriculture and the industry. Production of chitinase on an industrial scale requires high protein expression. Pichia pastoris yeast is an important host for the rapid production and high levels of recombinant proteins. In this project, the fungal chit33 enzyme was expressed and purified in Pichia pastoris X-33, and the purified enzyme was immobilised to enhance the sustainability, activity, and reuse on the magnetite κ-carrageenan/chitosan nanocomposite as a biocatalyst. The synthesised nanoparticle was characterised using FTIR, SEM and EDS analysis. According to the results of enzyme activity measurement under different pH conditions, the temperature and time of the stabilised enzyme showed better activity and stability than the free enzyme. Compared to free enzyme and chitosan beads, in the magnetic κ-carrageenan/chit36 substrate the specific activity, pH tolerance, optimum temperature of the enzyme was improved. The enzyme stabilised in the magnetic cariogenic/chit33 substrate at 70°C maintains about 80% of its enzyme activity relative to the magnetic chitosan/chit36 bead and maintains about 40% of its activity after eight cycles of re-use of the enzyme.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43125535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synergistic effect of DNA interfacing on carbon nanotube field effect transistor devices DNA界面对碳纳米管场效应晶体管器件的协同效应
International Journal of Nano and Biomaterials Pub Date : 2020-12-28 DOI: 10.1504/ijnbm.2020.10034538
L. Bharadwaj, Bishweshwar Pant, R. Rastogi
{"title":"Synergistic effect of DNA interfacing on carbon nanotube field effect transistor devices","authors":"L. Bharadwaj, Bishweshwar Pant, R. Rastogi","doi":"10.1504/ijnbm.2020.10034538","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10034538","url":null,"abstract":"Successful integration of carbon nanotubes (CNTs) in electronic devices and sensors requires controlled deposition at well defined locations and appropriate electrical contacts to metal electrodes/leads. Controlled self-assembly of CNTs can be achieved by interfacing them with biological molecule like DNA using its self-recognition property. However, these biointerfaces can produce undesirable changes in their device characteristics. Herein, we report an extensive study of effect of DNA interfacing on device characteristics of carbon nanotube field effect transistors and explored its synergistic effects as self-assembling element in future nanodevices. Single walled carbon nanotubes (SWNTs) are interfaced with DNA (via both covalent and non-covalent methodology) and electronic transport properties of corresponding field effect transistor devices have been studied in order to have an insight into changes in the electrical properties of SWNTs after interfacing. It was concluded that covalently linked DNA is not appropriate for self-assembly of carbon nanotubes in future nanodevices as it ruins its electrical characteristics.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46860143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Formulation, characterisation and comparison of different raloxifene hydrochloride loaded lipid-polymer hybrid nanoparticles 不同盐酸雷洛昔芬脂聚合物杂化纳米颗粒的制备、表征及比较
International Journal of Nano and Biomaterials Pub Date : 2020-12-28 DOI: 10.1504/ijnbm.2020.10034537
S. Mahmood, Tan Cheh Phey, Lee Seow Kheng, Ke Chen, U. Mandal
{"title":"Formulation, characterisation and comparison of different raloxifene hydrochloride loaded lipid-polymer hybrid nanoparticles","authors":"S. Mahmood, Tan Cheh Phey, Lee Seow Kheng, Ke Chen, U. Mandal","doi":"10.1504/ijnbm.2020.10034537","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10034537","url":null,"abstract":"This study aims to formulate raloxifene loaded lipid-polymeric hybrid nanoparticles (LPHNPs) and the comparison of their properties. Three LPHNPs, each with phosphatidylcholine-lipid (PCL) as bilayer-forming-membrane with three different polymers like sodium alginate, chitosan and poly(lactic-co-glycolic-acid) were prepared by nanoprecipitation, solvent injection and emulsion solvent evaporation, respectively. Results showed that the prepared formulations were spherical-shaped with a heterogeneity. Surface morphology was viewed using a scanning electron microscopy (SEM). A high entrapment efficiency (>70%) with a sustained and pH dependent drug release profile for 24 h was observed and evaluated using mathematical kinetic modelling. Fourier transform infrared spectroscopy was used to confirm successful entrapment of raloxifene after evaluating the interaction and compatibility of the excipients used. Whereas, differential scanning calorimetry and X-ray diffraction revealed the transformation of raloxifene into an amorphous form. In conclusion, these hybrid nanoparticles provide a promising approach for oral delivery of raloxifene.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46673664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Controlled hardware architecture for fractal image compression 分形图像压缩的受控硬件结构
International Journal of Nano and Biomaterials Pub Date : 2020-05-26 DOI: 10.1504/ijnbm.2020.10029634
M. K. Naskar, N. A. Hasanujjaman, U. Biswas
{"title":"Controlled hardware architecture for fractal image compression","authors":"M. K. Naskar, N. A. Hasanujjaman, U. Biswas","doi":"10.1504/ijnbm.2020.10029634","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10029634","url":null,"abstract":"Fractal image compression utilising algorithms have a high demand on the memory interface and the processor's arithmetic unit, which in turn fails to utilise the full capabilities of a general purpose processor. Since the algorithm is repetitive, the parallelisation reduces the time complexity of the otherwise expensive coding scheme. The design for FIC is proposed in this paper. It is based on the fact that the algorithm requires only integer arithmetic with repetitive use of the same data set. Making use of multiple functional units, controlled parallelism is introduced in this process. This makes encoding time 80 times faster than high level software implementation. It is 25 times faster than the assembly level implementation on a DSP processor.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44382318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Role of stress/strain mapping and random dopant fluctuation in advanced CMOS process technology nodes 应力/应变映射和随机掺杂波动在先进CMOS工艺技术节点中的作用
International Journal of Nano and Biomaterials Pub Date : 2020-05-26 DOI: 10.1504/ijnbm.2020.10029632
S. Das, S. Dey, E. Mohapatra, J. Jena, Tara Prasanna Dash, C. K. Maiti
{"title":"Role of stress/strain mapping and random dopant fluctuation in advanced CMOS process technology nodes","authors":"S. Das, S. Dey, E. Mohapatra, J. Jena, Tara Prasanna Dash, C. K. Maiti","doi":"10.1504/ijnbm.2020.10029632","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10029632","url":null,"abstract":"In this work, biaxial and uniaxial strain techniques are implemented in the channel for both p- and n-type FinFETs necessary for advanced CMOS applications. Stress/strain mapping in strained-Si (n-type) and strained-SiGe (p-type) channels (in trapezoidal tri-gate FinFET devices) are studied through three-dimensional (3D) numerical simulation, with particular focus on the enhancement of drain current. Following the strain/stress profiles simulated, the piezoresistive changes are implemented in the simulator to describe the strain effects on device operation. Further, we have investigated the impacts of random discrete dopant variability on the characteristics of a 14-nm gate length FinFET transistors (both n and p-type) using a 3D finite element quantum corrected drift-diffusion device simulator. We have also found the fluctuation of critical device parameters such as threshold voltage (VTH), sub-threshold slope (SS), on current (ION), and off state current (IOFF), etc., mainly originated from the randomness of distribution of the dopants.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45486200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Investigation on microstructures and phases of Fe-Ga alloy films deposited by magnetron sputtering 磁控溅射制备Fe-Ga合金薄膜的显微组织和物相研究
International Journal of Nano and Biomaterials Pub Date : 2020-05-26 DOI: 10.1504/ijnbm.2020.10029625
Jian-wu Yan, Ran Zhao, Y. Cha, Qingpeng Li
{"title":"Investigation on microstructures and phases of Fe-Ga alloy films deposited by magnetron sputtering","authors":"Jian-wu Yan, Ran Zhao, Y. Cha, Qingpeng Li","doi":"10.1504/ijnbm.2020.10029625","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10029625","url":null,"abstract":"Galfenol (Fe-Ga alloy), as a new magnetostrictive materials, has potentially wide applications in magnetostrictive devices. In this work, Fe-Ga alloy thin films were prepared by slice-style target magnetron sputtering and investigations on microstructures and phases of Fe-Ga alloy films were made to explore the relationship of properties and microstructures. The results show that the component of alloy thin film is related to physical properties of the material itself as well as the area ratio of the patch and target. The phase formed in the films in is disorderly A2 phase with face-centred cubic structure. The films prepared by magnetron sputtering exist in the form of polycrystalline with crystallographic texture perpendicular to the film plane. The structure shape of as-deposited specimens present a maze domain with different contrast and resolution and the magnetic domain decreased with the increase of the Ga content. With the increase of the Ga content, the magnetic domains become more and more irregular. Fe-Ga thin film morphology is related to the growth mode of the film. The microstructures of Fe-Ga alloy films can be controlled by magnetron sputtering technology.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47874942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Extended nucleic acid memory as the future of data storage technology 扩展核酸存储器作为数据存储技术的未来
International Journal of Nano and Biomaterials Pub Date : 2020-05-26 DOI: 10.1504/ijnbm.2020.10029630
S. Biswas, Subhrapratim Nath, J. Sing, S. Sarkar
{"title":"Extended nucleic acid memory as the future of data storage technology","authors":"S. Biswas, Subhrapratim Nath, J. Sing, S. Sarkar","doi":"10.1504/ijnbm.2020.10029630","DOIUrl":"https://doi.org/10.1504/ijnbm.2020.10029630","url":null,"abstract":"The amount of operational data being generated at an exponential rate in various spheres of computing, in turn, has culminated in a pressure on the available silicon memory-constrained by its limited capacity. In recent times, research has been undertaken on DNA computing for memory technology where nucleic acid memory (NAM) was formulated and found to be an efficient alternative for storing a large amount of digital data in the molecular space. This work presents a new encoding scheme which efficiently maps the binary data into a hybrid system of standard as well as non-standard genetic nucleotides to achieve a higher data capacity. Comparative studies have been done with existing encoding schemes, moreover, this work demonstrates the use of unnatural base pairs like Ds-Px and Im-Na which exhibit high stability and high selectivity in a DNA molecule.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49106692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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