{"title":"扩展核酸存储器作为数据存储技术的未来","authors":"S. Biswas, Subhrapratim Nath, J. Sing, S. Sarkar","doi":"10.1504/ijnbm.2020.10029630","DOIUrl":null,"url":null,"abstract":"The amount of operational data being generated at an exponential rate in various spheres of computing, in turn, has culminated in a pressure on the available silicon memory-constrained by its limited capacity. In recent times, research has been undertaken on DNA computing for memory technology where nucleic acid memory (NAM) was formulated and found to be an efficient alternative for storing a large amount of digital data in the molecular space. This work presents a new encoding scheme which efficiently maps the binary data into a hybrid system of standard as well as non-standard genetic nucleotides to achieve a higher data capacity. Comparative studies have been done with existing encoding schemes, moreover, this work demonstrates the use of unnatural base pairs like Ds-Px and Im-Na which exhibit high stability and high selectivity in a DNA molecule.","PeriodicalId":13999,"journal":{"name":"International Journal of Nano and Biomaterials","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Extended nucleic acid memory as the future of data storage technology\",\"authors\":\"S. Biswas, Subhrapratim Nath, J. Sing, S. Sarkar\",\"doi\":\"10.1504/ijnbm.2020.10029630\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The amount of operational data being generated at an exponential rate in various spheres of computing, in turn, has culminated in a pressure on the available silicon memory-constrained by its limited capacity. In recent times, research has been undertaken on DNA computing for memory technology where nucleic acid memory (NAM) was formulated and found to be an efficient alternative for storing a large amount of digital data in the molecular space. This work presents a new encoding scheme which efficiently maps the binary data into a hybrid system of standard as well as non-standard genetic nucleotides to achieve a higher data capacity. Comparative studies have been done with existing encoding schemes, moreover, this work demonstrates the use of unnatural base pairs like Ds-Px and Im-Na which exhibit high stability and high selectivity in a DNA molecule.\",\"PeriodicalId\":13999,\"journal\":{\"name\":\"International Journal of Nano and Biomaterials\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-05-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Nano and Biomaterials\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1504/ijnbm.2020.10029630\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Chemistry\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Nano and Biomaterials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1504/ijnbm.2020.10029630","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Chemistry","Score":null,"Total":0}
Extended nucleic acid memory as the future of data storage technology
The amount of operational data being generated at an exponential rate in various spheres of computing, in turn, has culminated in a pressure on the available silicon memory-constrained by its limited capacity. In recent times, research has been undertaken on DNA computing for memory technology where nucleic acid memory (NAM) was formulated and found to be an efficient alternative for storing a large amount of digital data in the molecular space. This work presents a new encoding scheme which efficiently maps the binary data into a hybrid system of standard as well as non-standard genetic nucleotides to achieve a higher data capacity. Comparative studies have been done with existing encoding schemes, moreover, this work demonstrates the use of unnatural base pairs like Ds-Px and Im-Na which exhibit high stability and high selectivity in a DNA molecule.
期刊介绍:
In recent years, frontiers of research in engineering, science and technology have been driven by developments in nanomaterials, encompassing a diverse range of disciplines such as materials science, biomedical engineering, nanomedicine and biology, manufacturing technology, biotechnology, nanotechnology, and nanoelectronics. IJNBM provides an interdisciplinary vehicle covering these fields. Advanced materials inspired by biological systems and processes are likely to influence the development of novel technologies for a wide variety of applications from vaccines to artificial tissues and organs to quantum computers. Topics covered include Nanostructured materials/surfaces/interfaces Synthesis of nanostructures Biological/biomedical materials Artificial organs/tissues Tissue engineering Bioengineering materials Medical devices Functional/structural nanomaterials Carbon-based materials Nanomaterials characterisation Novel applications of nanomaterials Modelling of behaviour of nanomaterials Nanomaterials for biomedical applications Biological response to nanomaterials.