International journal of hygiene and environmental health最新文献

{"title":"Association of early life co-exposure to ambient PM2.5 and O3 with the offspring's growth within two years of age: A birth cohort study","authors":"Yu Liu ,&nbsp;Kunying Li ,&nbsp;Yuchuan Deng ,&nbsp;Mengfan Li ,&nbsp;Xiaonan Gu ,&nbsp;Yujing Chen ,&nbsp;Zhaoyan Liu ,&nbsp;Lizi Lin ,&nbsp;Li Cai","doi":"10.1016/j.ijheh.2025.114520","DOIUrl":"10.1016/j.ijheh.2025.114520","url":null,"abstract":"<div><h3>Background</h3><div>Previous studies indicated that early life exposure to particulate matter of 2.5 μm or less (PM_2.5) could impair children's growth. However, the adverse effects of maternal ozone (O₃) and its interplay with PM_2.5 on offspring's growth are unclear.</div></div><div><h3>Object</h3><div>We aimed to investigate the independent and combined association of early-life exposure to PM_2.5 and O₃ with offspring growth in early childhood.</div></div><div><h3>Methods</h3><div>This study included 632 Chinese mother-child pairs. Residential PM_2.5 and O₃ exposure concentrations in pregnancy and postanal 2 years were estimated by an established spatiotemporal model. During each exposure period, we also calculated the exceedance rate, the accumulative proportion of over-standard days (Exceedance standard: PM_2.5&gt;35 μg/m³, O₃ &gt; 100 μg/m³). We repeatedly measured the offspring's weight and length from birth to 2 years old and calculated the age-standardized Z-score of weight for height (WFL), body mass index (BMI), and overweight risk (BMI Z-score &gt;85th percentile).</div></div><div><h3>Results</h3><div>The adjusted generalized estimating equations showed that the concentration (an IQR increase) and exceedance rate (per 10% increase) of PM_2.5 in prenatal (especially the second trimesters) and postnatal periods were associated with increased WFL, BMI Z-score, and overweight risk (βs/ORs ranging from 0.10 to 0.41/1.23 to 1.62, <em>P</em> &lt; 0.05) in children within age 2 years. Although early-life exposure to O₃ was not associated with growth outcomes, it showed multiplicative and additive interactions with PM_2.5 on offspring growth, particularly in the 2nd trimester and early life 1000 days. The associations with WFL and BMI Z-score were greatest in the higher exceedance rates group of PM_2.5 and O₃ (βs ranging from 0.21 to 0.37, <em>P</em> _<em>for</em> _{<em>interaction</em>}&lt;0.01).</div></div><div><h3>Conclusion</h3><div>This study demonstrated that early-life PM_2.5 exposure, especially exceedance rate, was associated with increased offspring growth within 2 years of age. Furthermore, we discovered that O₃ may strengthen the adverse effect of PM_2.5 exposure on children's growth.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114520"},"PeriodicalIF":4.5,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142981066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the reliability and validity of pictorial-assisted 24-h recall for measuring hand hygiene and child faeces disposal: A cross-sectional study in Malawi","authors":"Olivier Rizk ,&nbsp;Sarah Bick ,&nbsp;Blessings White ,&nbsp;Kondwani Chidziwisano ,&nbsp;Robert Dreibelbis","doi":"10.1016/j.ijheh.2024.114516","DOIUrl":"10.1016/j.ijheh.2024.114516","url":null,"abstract":"<div><div>Whilst improving hygiene and sanitation behaviours is key to cost-effective and sustainable water, sanitation and hygiene interventions, measuring behaviour change remains a challenge. This study assessed the validity and reliability of pictorial 24-h recall (P24 hR), a novel method using unprompted recall of past activities through pictures, compared to structured observation for measuring handwashing with soap (HWWS) and safe child faeces disposal in rural Malawi. Data were collected from 88 individuals across 74 households in Chiradzulu district using both methods over a two-day period, with the recall period of the P24 hR corresponding to the period of structured observation completed the previous day. Results showed poor agreement between P24 hR and observations in detection of hygiene opportunities and behaviours. P24 hR under-reported handwashing opportunities when frequency was high and over-reported them when frequency was low. The 95% limits of agreement for handwashing opportunities estimated through Bland-Altman analysis (−7.62 to 4.89) were unacceptably wide given median 5 opportunities observed per participant. P24 hR also over-reported HWWS and safe child faeces disposal, and kappa statistics indicated agreement no better than by chance. Structured observation remains the better method for measuring hygiene behaviours as compared to the P24 hR method despite its known limitations, including potential reactivity bias.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114516"},"PeriodicalIF":4.5,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behaviour change interventions to improve household sanitation and hygiene practices in urban settings: A systematic scoping review","authors":"Clara MacLeod ,&nbsp;Katherine Davies ,&nbsp;Mwamba M. Mwenge ,&nbsp;Jenala Chipungu ,&nbsp;Oliver Cumming ,&nbsp;Robert Dreibelbis","doi":"10.1016/j.ijheh.2025.114519","DOIUrl":"10.1016/j.ijheh.2025.114519","url":null,"abstract":"<div><h3>Introduction</h3><div>Behaviour change interventions have the potential to improve sanitation and hygiene practices in urban settings. However, evidence on which behaviour change interventions have successfully improved sanitation and hygiene practices in urban settings is unclear.</div></div><div><h3>Methods</h3><div>We performed electronic searches across five databases and one grey literature database to identify relevant studies published between January 1, 1990 and November 20, 2023 in English. Eligible study designs included randomised and non-randomised controlled trials with a concurrent control. Studies were eligible for inclusion if they reported a behaviour change intervention for improving sanitation and/or hygiene practices in an urban setting. Individual behaviour change intervention components were mapped to one of nine intervention functions of the capabilities, opportunities, motivations, and behaviour (COM-B) framework. Risk of bias was assessed for each study using an adapted Newcastle-Ottawa scale.</div></div><div><h3>Results</h3><div>After de-duplication, 8249 documents were screened by abstract and title, with 79 documents retrieved for full-text screening. We included 13 studies ranging from low- to high-quality. The behaviour change interventions had mixed effects on sanitation and hygiene practices in urban settings. Specifically, interventions improved latrine quality but not safe child faeces disposal. Interventions often improved handwashing with soap at key times and sometimes increased the presence of soap and water at the handwashing facility, used as a proxy measure for handwashing. There is limited evidence on food hygiene practices. Most behavioural outcomes were measured between 6 and 12 months after intervention implementation, which may undermine the sustainability of behaviour change interventions.</div></div><div><h3>Conclusion</h3><div>Despite overall mixed behavioural effects on sanitation and hygiene practices, behaviour change interventions can improve certain behaviours in urban settings, such as latrine quality improvements and handwashing with soap at the household or compound level. More ambitious behaviour change interventions are needed to reduce disparities in sanitation and hygiene access in urban areas globally.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114519"},"PeriodicalIF":4.5,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proximity to petrochemical industry and risk of childhood asthma occurrence","authors":"Shih-Chun Pan ,&nbsp;Wei-Shan Chin ,&nbsp;Ching-Chun Huang ,&nbsp;Yu-Cheng Chen ,&nbsp;Chih-Da Wu ,&nbsp;Chin-Yu Hsu ,&nbsp;Pinpin Lin ,&nbsp;Pau-Chung Chen ,&nbsp;Yue Leon Guo","doi":"10.1016/j.ijheh.2024.114515","DOIUrl":"10.1016/j.ijheh.2024.114515","url":null,"abstract":"<div><div>Adverse effects on the respiratory system were associated with intensive petroleum-related industrial activities. The study aimed to assess the impact of petrochemical exposure on childhood asthma using various surrogate indices. A singleton birth cohort from 2004 to 2017 was conducted, leveraging two linked nationwide databases in Taiwan. The distance from the nearest petrochemical industrial parks (PIPs), the probability for PIPs exposure, and benzene exposure level were used as surrogate petrochemical exposure indices. Both prenatal and postnatal exposure window were considered. The Cox proportional hazard models were applied to evaluate the effects. A total of 461,343 asthma cases were identified in this cohort by December 31, 2018. Certain risk factors such as being male, preterm birth, low birth weight, Caesarean delivery, maternal gestational hypertension, and gestational diabetes, were more prevalent in children with asthma than in those without. The results indicated an increased risk of asthma for those living near PIPs or with a higher probability for PIPs exposure during prenatal and/or postnatal periods. Increased asthma risks were also observed with higher levels of benzene exposure during either the prenatal or postnatal periods. Proximity to PIPs is associated with an increased risk of childhood asthma, as indicated by three different exposure surrogate exposure indices. This underscores the significant impact of petrochemical exposure on the occurrence of childhood asthma.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114515"},"PeriodicalIF":4.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between anthropogenic heat and parent-report symptoms of childhood attention deficit hyperactivity disorder in China: A novel perspective reflecting climate change","authors":"Tao Yu ,&nbsp;Yue Wen ,&nbsp;Pei-Pei Dong ,&nbsp;Ming-Kun Sun ,&nbsp;Samantha E. Qian ,&nbsp;Mario Schootman ,&nbsp;Michael G. Vaughn ,&nbsp;Shu-Li Xu ,&nbsp;He-Hai Huang ,&nbsp;Feng-Wen Shan ,&nbsp;Shi-Fu Zhu ,&nbsp;Jing-Yao Wang ,&nbsp;Cheng Li ,&nbsp;Zhao-Huan Gui ,&nbsp;Ru-Qing Liu ,&nbsp;Li-Wen Hu ,&nbsp;Li-Zi Lin ,&nbsp;Zhong Lin ,&nbsp;Guang-Hui Dong","doi":"10.1016/j.ijheh.2024.114518","DOIUrl":"10.1016/j.ijheh.2024.114518","url":null,"abstract":"<div><div>Anthropogenic climate change will have a negative impact on worldwide well-being over and above the direct consequences of rising average temperatures. But anthropogenic heat (AH) relationship with childhood attention deficit hyperactivity disorder (ADHD) is unknown. To assess the relationship with AH exposure and childhood ADHD symptoms in the context of global climate change, this study was conducted in a cross-sectional survey from April 2012 to May 2018 in the northeastern, northwestern, and southern regions of China, with a total enrollment of 179,846 children aged 6–18 years. Exposure to AH was evaluated by gathering socioeconomic and energy usage data along with nighttime light data from satellites and data on the Normalized Difference Vegetation Index. This encompassed four types of AH exposure: industrial processes, transportation, buildings, and human metabolism. The statistical analysis used generalized linear mixed-effects modeling to determine the association between the types of AH exposure and childhood ADHD symptoms. The mean (SD) age of the 179,846 study participants was 11.7 (2.9) years, and 7343 participants (4.1%) had ADHD symptoms. In adjusted models, increased levels of AH exposure per IQR from total AH, industry, transportation, buildings, and human metabolism all increased the odds of ADHD (odds ratios, 3.60 [95% CI, 3.42, 3.80]; 5.71 [95% CI, 5.32, 6.14]; 1.79 [95% CI, 1.75, 1.84]; 2.10 [95% CI, 2.03, 2.17]; 1.95 [95% CI, 1.89, 2.02]). The association remained robust after various sensitivity analyses. Prolonged exposure to AH is associated with the development of ADHD symptoms in children.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114518"},"PeriodicalIF":4.5,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradation of trimethoprim and sulfamethoxazole in secondary effluent by microalgae-bacteria consortium","authors":"Daniel Aparecido da Silva Rodrigues ,&nbsp;Camila Cristina Rodrigues Ferreira da Cunha ,&nbsp;Andressa Rezende Pereira ,&nbsp;Daiana Rocha do Espírito Santo ,&nbsp;Silvana de Queiroz Silva ,&nbsp;Maria Clara Vieira Martins Starling ,&nbsp;Aníbal da Fonseca Santiago ,&nbsp;Robson José de Cássia Franco Afonso","doi":"10.1016/j.ijheh.2024.114517","DOIUrl":"10.1016/j.ijheh.2024.114517","url":null,"abstract":"<div><div>Trimethoprim (TMP) and sulfamethoxazole (SMX) are bacteriostatic agents, which are co-administered to patients during infection treatment due to their synergetic effects. Once consumed, TMP and SMX end up in wastewater and are directed to municipal wastewater treatment plants (WWTPs) which fail to remove these contaminants from municipal wastewater. The discharge of WWTP effluents containing antibiotics in the environment is a major concern for public health as it contributes to the spread of antimicrobial resistance. Improving treatment applied in WWTPs is one of the measures to tackle this issue. In this study, a natural microalgae-bacteria consortium cultivated under low intensity LED irradiation was used as a quaternary treatment to assess the removal of TMP alone (50 μg L⁻¹) and also mixed with SMX (TMP/SMX; 50 μg L⁻¹ of each) from real WWTP secondary effluents from anaerobic treatment systems. The removal of the sulfonamide resistance gene, <em>sul1</em>, was also evaluated. This is the first study assessed the removal of TMP alone and TMP associated with SMX in real effluent using microalgae-bacteria consortium without nutrient enrichment. Biodegradation experiments were conducted for 7 days, residual amount of antibiotics were assessed by low-temperature partitioning extraction (LTPE) followed by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) and <em>sul1</em> was analyzed by quantitative Polymerase Chain Reaction (qPCR). Results showed that SMX removal (48.34%) was higher than TMP (24.58%) in the mixture. The presence of both antibiotics at 50 μg L⁻¹ did not inhibit microalgae-bacteria consortium growth. After 7 days, there was a slight increase in the absolute abundance of <em>sul1</em> and 16S rRNA. The main removal mechanism for both antibiotics might be attributed to symbiotic biodegradation as bioadsorption, bioaccumulation and abiotic factors were very low or insignificant. While the application of a microalgae-bacteria consortium as a quaternary treatment seems to be a promising alternative, further research to improve degradation rate aiming at a global removal &gt;80% as required in the Swiss and European directives is encouraged.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114517"},"PeriodicalIF":4.5,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pathway-based genetic score for inflammation: An indicator of vulnerability to phthalate-induced adverse neurodevelopment outcomes","authors":"Ahmed Elagali ,&nbsp;Alex Eisner ,&nbsp;Samuel Tanner ,&nbsp;Katherine Drummond ,&nbsp;Christos Symeonides ,&nbsp;Chloe Love ,&nbsp;Mimi LK. Tang ,&nbsp;Toby Mansell ,&nbsp;David Burgner ,&nbsp;Fiona Collier ,&nbsp;Peter D. Sly ,&nbsp;Martin O'Hely ,&nbsp;Sarah Dunlop ,&nbsp;Peter Vuillermin ,&nbsp;Anne-Louise Ponsonby","doi":"10.1016/j.ijheh.2024.114514","DOIUrl":"10.1016/j.ijheh.2024.114514","url":null,"abstract":"<div><h3>Introduction</h3><div>Phthalates, chemical additives used to enhance plastic products' flexibility, are easily released into the environment, and can harm the brain development through various mechanisms including inflammation. Genetic variation influencing an individual's susceptibility to inflammation may play a role in the effects of phthalate exposure on neurodevelopment however there is no summary measure developed for genetic susceptibility to inflammation.</div></div><div><h3>Methods</h3><div>We developed a genetic pathway function score for inflammation (gPFSⁱⁿ), based on the transcriptional activity of the inflammatory response pathway in the brain and other tissues. Using the Barwon Infant Study (a birth cohort of <em>n</em> = 1074), we examined the connection between gPFSⁱⁿ and key neurodevelopmental outcomes, along with the interplay between prenatal phthalate levels, children's genetic susceptibility to inflammation (gPFSⁱⁿ), and adverse neurodevelopmental outcomes.</div></div><div><h3>Results</h3><div>Regression techniques revealed consistent associations between gPFSⁱⁿ-phthalate combinations and key neurodevelopmental outcomes. A high gPFSⁱⁿ score was associated with an increased risk of doctor-diagnosed Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) by age 11.5 years, with adjusted odds ratios of 2.15(<em>p</em> = 0.039) and 2.42(<em>p</em> = 0.005), respectively. Furthermore, individuals with both high gPFSⁱⁿ and prenatal phthalate exposure exhibited more neurodevelopmental problems. This included associations of high gPFSⁱⁿ and bis(2-ethylhexyl) phthalate (DEHP) levels with parent-reported ASD traits and doctor-diagnosed ASD. The attributable proportions due to this interaction were 0.39 (p = 0.045) and 0.37 (p = 0.037), respectively.</div></div><div><h3>Conclusion</h3><div>These findings contribute to the evidence linking gestational phthalate exposure and inflammation to adverse neurodevelopment and underscoring increased risks in children with higher genetic susceptibility to inflammation.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114514"},"PeriodicalIF":4.5,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study","authors":"Minqi Liao ,&nbsp;Siqi Zhang ,&nbsp;Kathrin Wolf ,&nbsp;Gabriele Bolte ,&nbsp;Michael Laxy ,&nbsp;Lars Schwettmann ,&nbsp;Annette Peters ,&nbsp;Alexandra Schneider ,&nbsp;Ute Kraus","doi":"10.1016/j.ijheh.2024.114513","DOIUrl":"10.1016/j.ijheh.2024.114513","url":null,"abstract":"<div><h3>Background</h3><div>Little is known about the association between air pollution and self-perceived health (including both health-related quality of life [HRQoL] and self-rated health [SRH]). The aim of this study was therefore to explore whether long-term air pollution exposure is associated with worse self-perceived health, as measured by different tools.</div></div><div><h3>Methods</h3><div>We used a land-use regression model to determine the annual average levels of particulate matter with a diameter &lt;10 μm (PM₁₀), coarse particles (PM_coarse), fine particles (PM_2.5), fine particle absorbances (PM_2.5abs), particle number concentration (PNC), ozone (O₃), nitrogen dioxide (NO₂), and nitrogen oxide (NO_X) for geocoded residential addresses (2014–2015). Questionnaires and face-to-face interviews were used to collect HRQoL (measured using the European Quality of Life 5 Dimensions [EQ-5D] index and the European Quality of Life Visual Analogue Scale [EQ-VAS]) and SRH indicators (measured through two survey questions) (2018–2019) from participants of the Cooperative Health Research in the Region of Augsburg (KORA)-Fit study in Germany. We explored associations via generalized additive models, multinomial logistic regression, and logistic regression.</div></div><div><h3>Results</h3><div>We included 2610 participants with a mean age of 64.0 years in this cross-sectional study, of which 1428 (54.7%) were female. Each interquartile range (IQR) increase in O₃ was associated with a reduced EQ-5D index value (% change of mean points and 95% confidence interval: -0.91% [-1.76; -0.06]). The average EQ-VAS score declined between -1.57% and -0.96% with each IQR increase in PM₁₀, PM_coarse, PM_2.5abs, PNC, NO₂, and NO_X. These pollutants were associated with increased occurrence of poor SRH, with odds ratios ranging from 1.24 to 2.67. PM_2.5abs was linked to a higher likelihood of reporting a worse comparative SRH (2.59 [1.12; 5.99]). Body mass index and self-perceived stress modified these associations.</div></div><div><h3>Conclusions</h3><div>Long-term air pollution exposure was associated with poor self-perceived health, presenting as lower HRQoL and higher odds of poor SRH. Single-item indicators measuring self-perceived health status may work better than multi-dimensional indicators.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114513"},"PeriodicalIF":4.5,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of urinary levels of trace metals with type 2 diabetes and obesity in postmenopausal women in Korea: A community-based cohort study","authors":"Min Kyong Moon ,&nbsp;Gowoon Lee ,&nbsp;Sohyeon Choi ,&nbsp;Inae Lee ,&nbsp;Aram Lee ,&nbsp;Min Joo Kim ,&nbsp;Suhyun Park ,&nbsp;Yoon Hee Cho ,&nbsp;Young Joo Park ,&nbsp;Sohee Oh ,&nbsp;Jeongim Park ,&nbsp;Nam H. Cho ,&nbsp;Kyungho Choi","doi":"10.1016/j.ijheh.2024.114508","DOIUrl":"10.1016/j.ijheh.2024.114508","url":null,"abstract":"<div><div>Several toxic metals have been associated with metabolic diseases like obesity and diabetes mellitus (DM) in humans. However, knowledge regarding the influence of many trace elements, especially in combination with essential elements is limited. This study aims to address this research gap by investigating the associations of both non-essential and essential inorganic trace elements in urine with DM and obesity, employing a group of postmenopausal women (<em>n</em> = 851) from the Korean Genome and Epidemiology Study (KoGES) cohort. Urine samples were collected during 2017–2018, and were analyzed for 19 trace elements using inductively coupled plasma–mass spectrometry and an automatic mercury analyzer. Outcomes of interest were metabolic diseases (DM and obesity) and DM-related traits (insulin resistance and β-cell function). After adjustment of covariates, such as age, alcohol consumption, smoking status, educational level, and daily energy intake, urinary Zn, Ni, Tl, and U levels were associated with the prevalence of DM and homeostatic model assessment (HOMA) for insulin resistance (IR) in the postmenopausal women. In the whole mixture model, however, no significant association was observed for the prevalence of DM. Urinary levels of Zn were negatively associated with HOMA of β-cell function (HOMA-β), positively correlated with HbA1c levels, HOMA-IR, and prevalent DM. In addition, urinary Zn, Co, Tl, and Cs were positively associated with obesity (body mass index ≥25 kg/m²). The present observation shows that several individual elements and their mixtures may be associated with the prevalence of DM, IR, or obesity.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114508"},"PeriodicalIF":4.5,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical urban environment and cardiometabolic diseases in the five largest Bulgarian cities","authors":"Angel M. Dzhambov ,&nbsp;Donka Dimitrova ,&nbsp;Angel Burov ,&nbsp;Marco Helbich ,&nbsp;Iana Markevych ,&nbsp;Mark J. Nieuwenhuijsen","doi":"10.1016/j.ijheh.2024.114512","DOIUrl":"10.1016/j.ijheh.2024.114512","url":null,"abstract":"<div><div>This study investigated the associations between residential environmental characteristics and the prevalence of cardiometabolic diseases in the five largest Bulgarian cities. Representative cross-sectional survey data (N = 4640 adults) was collected in Sofia, Plovdiv, Varna, Burgas, and Ruse. Participants self-reported diagnosis or medication intake for hypertension, ischemic heart disease (IHD), stroke, and diabetes mellitus, as well as domestic burning of solid fuel and having a domestic garden. Residential addresses were linked to greenspace (overall vegetation level, tree cover, urban greenspace), bluespace, walkability, air pollution (NO₂), and traffic noise (L_den). In the 300 m buffer, bluespace presence was inversely associated with hypertension (odds ratio [OR] = 0.67; 95% CI: 0.45, 1.00), IHD (OR = 0.45; 95% CI: 0.21, 0.99), and diabetes (OR = 0.51; 95% CI: 0.25, 1.04). Higher walkability and tree cover were inversely associated with hypertension (OR _{per 2 units} = 0.85; 95% CI: 0.75, 0.96) and diabetes (OR _{per 10%} = 0.77; 95% CI: 0.62, 0.97), respectively. These associations were stronger in larger buffers. Solid fuel burning was associated with IHD (OR = 1.63; 95% CI: 1.07, 2.50). There was an indication of a positive association between aircraft L_den and both stroke and IHD. The direction of the associations for domestic gardens, NO₂, road traffic and railway L_den was counterintuitive. We detected some nonlinear associations. In conclusion, people living in urban neighborhoods that were more walkable, closer to bluespace, and greener had lower prevalence of cardiometabolic diseases, while solid fuel burning was associated with higher odds of cardiovascular diseases. Unexpected associations with some exposures may be due to unaccounted for urban fabric characteristics. This study is among the first assessing an understudied region in Southeastern Europe. Its findings have the potential to inform public discourse and provide evidence to support the implementation of urban design conducive to cardiometabolic health.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114512"},"PeriodicalIF":4.5,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}