International journal of hygiene and environmental health最新文献

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Corrigendum to “Normalised difference vegetation index and allergies among four-year-old children living in the greater Tokyo area, Japan: Findings from an Adjunct Study of the Japan Environment and Children's Study” [Int. J. Hygiene Environ. Health 275 (2026) 114812] 《日本大东京地区四岁儿童的植被指数和过敏症的标准化差异:日本环境与儿童研究的辅助研究结果》的勘误表[j]。J.卫生环境。健康275(2026)114812]。
IF 4.3 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-07-01 Epub Date: 2026-06-12 DOI: 10.1016/j.ijheh.2026.114846
Hongwei Jiang, Zin Wai Htay, Makiko Sekiyama, Keiichi Kimura, Kazuaki Tsuchiya, Yayoi Kobayashi, Daisuke Harama, Miori Sato, Shoji F. Nakayama, Shin Yamazaki
{"title":"Corrigendum to “Normalised difference vegetation index and allergies among four-year-old children living in the greater Tokyo area, Japan: Findings from an Adjunct Study of the Japan Environment and Children's Study” [Int. J. Hygiene Environ. Health 275 (2026) 114812]","authors":"Hongwei Jiang, Zin Wai Htay, Makiko Sekiyama, Keiichi Kimura, Kazuaki Tsuchiya, Yayoi Kobayashi, Daisuke Harama, Miori Sato, Shoji F. Nakayama, Shin Yamazaki","doi":"10.1016/j.ijheh.2026.114846","DOIUrl":"10.1016/j.ijheh.2026.114846","url":null,"abstract":"","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"276 ","pages":"Article 114846"},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148240845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urinary biomarkers of oxidative stress and their association with isocyanate and epoxy exposure in industrial painters 工业画家尿液氧化应激生物标志物及其与异氰酸酯和环氧树脂暴露的关系。
IF 4.3 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-07-01 Epub Date: 2026-06-26 DOI: 10.1016/j.ijheh.2026.114854
Paridhi Patel, Anila Bello, Natalia Palacios, Dhimiter Bello
{"title":"Urinary biomarkers of oxidative stress and their association with isocyanate and epoxy exposure in industrial painters","authors":"Paridhi Patel,&nbsp;Anila Bello,&nbsp;Natalia Palacios,&nbsp;Dhimiter Bello","doi":"10.1016/j.ijheh.2026.114854","DOIUrl":"10.1016/j.ijheh.2026.114854","url":null,"abstract":"<div><h3>Background</h3><div>Industrial painters (IPs) are routinely exposed to complex mixtures of reactive chemicals, including isocyanates and epoxy resins used in metal coating systems and spray polyurethane foam (SPF) applicators. Oxidative stress (OS), resulting from an imbalance between reactive oxygen species and antioxidant defenses, is a key mechanism of toxic injury linked to numerous diseases like cancer, asthma, dermatitis, and neurotoxicity. However, data on OS markers among IPs are limited.</div></div><div><h3>Objectives</h3><div>To characterize urinary OS biomarker concentrations in IPs and SPF applicators and evaluate their associations with urinary biomarkers of isocyanate and epoxy exposure.</div></div><div><h3>Methods</h3><div>Pre- and post-shift urine samples were collected from 50 workers applying either isocyanate-based top-coats or epoxy-based mid-coats and SPF. Nine urinary OS biomarkers were analyzed to reflect DNA/RNA damage (8-hydroxy-2′-deoxyguanosine [8OHdG], 8-hydroxyguanosine [8OHG], 5-hydroxymethyluracil [5OHMeU]), protein oxidation (o-tyrosine, 3-chlorotyrosine, 3-nitrotyrosine), and lipid peroxidation (8-isoprostane, 4-hydroxynonenal [4-HNE], malondialdehyde [MnDAI]). Associations between OS and exposure biomarkers were evaluated using multivariable linear regression adjusted for creatinine and age.</div></div><div><h3>Results</h3><div>Top-coat painters exhibited significant post-shift increases in 8OHdG, 8OHG, and 3-nitrotyrosine, whereas o-tyrosine and 4-HNE decreased. After adjustment, 8OHdG was positively associated with isocyanate (top-coat) and epoxy (mid-coat) exposure, while 4-HNE was inversely associated with isocyanate exposure. Workers with severe dehydration (specific gravity &gt;1.030) had significantly higher composite OS scores.</div></div><div><h3>Conclusions</h3><div>Exposure to reactive coating formulations in IPs and SPF induces measurable oxidative stress, likely via multiple mechanisms, including depletion of the antioxidant pools, impaired antioxidant defenses and direct attack on sensitive biomolecules. Elevated urinary OS biomarkers and their association with exposure metrics highlight the need for improved exposure controls and increased risk of chronic disease development in this workforce.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"276 ","pages":"Article 114854"},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148341709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Water management practices under climate and infrastructure stress in Zaatari Refugee Camp: A gendered qualitative study 扎塔里难民营气候和基础设施压力下的水管理实践:性别定性研究。
IF 4.3 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-07-01 Epub Date: 2026-07-03 DOI: 10.1016/j.ijheh.2026.114860
Natasha Hessami, Alaeddin Al-Hammadi, Motaz Rawashdeh, Maha Al-Harahsheh, Raghad Abu Samra, Rawan Iriqat, Samer Makahleh, Wael K Al-Delaimy
{"title":"Water management practices under climate and infrastructure stress in Zaatari Refugee Camp: A gendered qualitative study","authors":"Natasha Hessami,&nbsp;Alaeddin Al-Hammadi,&nbsp;Motaz Rawashdeh,&nbsp;Maha Al-Harahsheh,&nbsp;Raghad Abu Samra,&nbsp;Rawan Iriqat,&nbsp;Samer Makahleh,&nbsp;Wael K Al-Delaimy","doi":"10.1016/j.ijheh.2026.114860","DOIUrl":"10.1016/j.ijheh.2026.114860","url":null,"abstract":"<div><h3>Background</h3><div>Climate change–related heatwaves and dust storms increasingly strain water, sanitation, and hygiene (WaSH) systems in displacement settings, yet little is known about how households manage water scarcity during acute climate events. Gendered roles and responsibilities in refugee camps may further influence how water scarcity is managed. This study examines how household water management practices intersect with psychosocial stress during extreme summer conditions in Zaatari Refugee Camp, Jordan.</div></div><div><h3>Methods</h3><div>We conducted a qualitative study using gender-stratified focus group discussions with adult Syrian refugees in Zaatari Refugee Camp. Semi-structured focus groups explored experiences of water access, household water management, and stress during summer heatwaves and dust storms. Data were analyzed using inductive thematic analysis with participatory validation involving refugee co-facilitators.</div></div><div><h3>Results</h3><div>Participants described uneven WaSH system functioning driven by timing, pressure, and geographic location, alongside predictable summer reductions in water supply and increased demand during heatwaves and dust storms. Households and individuals employed creative water conservation strategies that were effective but amplified stress through sustained vigilance and restriction. Importantly, women more frequently reported responsibility for monitoring, rationing, and enforcing water use, alongside greater psychosocial strain, while men described episodic stress related to system failures or water procurement.</div></div><div><h3>Conclusion</h3><div>In displacement contexts, water scarcity functions as a chronic psychosocial stressor shaped by infrastructure, acute climate events, and gendered household responsibilities. Addressing water insecurity in protracted displacement settings requires integrated WaSH approaches that extend beyond infrastructure to include mental wellbeing, gender-responsive programming, and meaningful engagement of refugees as lived-experience experts in governance and intervention design.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"276 ","pages":"Article 114860"},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148383464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Book of Abstracts: OHSI/ISES Europe joint 2026 Workshop; Dublin, Ireland, June 10th – 11th, 2026 摘要:OHSI/ISES欧洲联合2026研讨会;爱尔兰都柏林,2026年6月10日至11日。
IF 4.3 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-07-01 Epub Date: 2026-06-02 DOI: 10.1016/j.ijheh.2026.114840
Alison Connolly
{"title":"Book of Abstracts: OHSI/ISES Europe joint 2026 Workshop; Dublin, Ireland, June 10th – 11th, 2026","authors":"Alison Connolly","doi":"10.1016/j.ijheh.2026.114840","DOIUrl":"10.1016/j.ijheh.2026.114840","url":null,"abstract":"","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"276 ","pages":"Article 114840"},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148152899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Pesticide exposure profiles through tap water consumption in the NutriNet-Santé cohort in 2022: a cross-sectional analysis using the French SISE-Eaux monitoring database” [Int. J. Hygiene Environ. Health 274 (2026) 114792] “2022年nutrinet - sant<s:1>人群中通过自来水摄入的农药暴露概况:使用法国SISE-Eaux监测数据库的横断面分析”的勘误表[Int]。J.卫生环境。健康274(2026)114792]。
IF 4.4 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-06-01 Epub Date: 2026-05-22 DOI: 10.1016/j.ijheh.2026.114810
Emma Meyer , Justine Berlivet , Mathilde Touvier , Philippe Pointereau , Denis Lairon , Serge Hercberg , Laurence Gamet-Payrastre , Rodolphe Vidal , Emmanuelle Kesse-Guyot , Julia Baudry
{"title":"Corrigendum to “Pesticide exposure profiles through tap water consumption in the NutriNet-Santé cohort in 2022: a cross-sectional analysis using the French SISE-Eaux monitoring database” [Int. J. Hygiene Environ. Health 274 (2026) 114792]","authors":"Emma Meyer ,&nbsp;Justine Berlivet ,&nbsp;Mathilde Touvier ,&nbsp;Philippe Pointereau ,&nbsp;Denis Lairon ,&nbsp;Serge Hercberg ,&nbsp;Laurence Gamet-Payrastre ,&nbsp;Rodolphe Vidal ,&nbsp;Emmanuelle Kesse-Guyot ,&nbsp;Julia Baudry","doi":"10.1016/j.ijheh.2026.114810","DOIUrl":"10.1016/j.ijheh.2026.114810","url":null,"abstract":"","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"275 ","pages":"Article 114810"},"PeriodicalIF":4.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148007796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal blood lead level and its association with birthweight and preterm birth in Adjara, Georgia: An inverse probability of selection weighting analysis of a population-based cohort study 在格鲁吉亚的Adjara,母亲血铅水平及其与出生体重和早产的关系:一项基于人群的队列研究的逆概率选择加权分析。
IF 4.4 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-06-01 Epub Date: 2026-05-24 DOI: 10.1016/j.ijheh.2026.114825
Tinatin Manjavidze , Erik Anda , Ingvild Hersoug Nedberg , Sophio Sikharulidze , Rusudan Shavishvili , Nona Ephadze , Charlotta Rylander
{"title":"Maternal blood lead level and its association with birthweight and preterm birth in Adjara, Georgia: An inverse probability of selection weighting analysis of a population-based cohort study","authors":"Tinatin Manjavidze ,&nbsp;Erik Anda ,&nbsp;Ingvild Hersoug Nedberg ,&nbsp;Sophio Sikharulidze ,&nbsp;Rusudan Shavishvili ,&nbsp;Nona Ephadze ,&nbsp;Charlotta Rylander","doi":"10.1016/j.ijheh.2026.114825","DOIUrl":"10.1016/j.ijheh.2026.114825","url":null,"abstract":"<div><h3>Background</h3><div>Lead exposure poses significant health risks, particularly during pregnancy, as lead affects fetal development. This study aimed to evaluate the association between maternal blood lead levels (BLL), birthweight and preterm birth in Adjara, Georgia.</div></div><div><h3>Methods</h3><div>Using the nationwide Georgian Birth Registry, we included data on all singleton births in Adjara between 1<sup>st</sup>July 2021 and December 2023 (n = 13,911) among women who attended antenatal care. Propensity scores and inverse probability of selection (IPS) weights were calculated to balance the characteristics of women with BLL test (n = 7076) and without (n = 6835). IPS-weighed multivariable linear regression model was used to assess the association between maternal BLLs and birthweight, while IPS-weighted multivariable logistic regression models were used to assess associations between maternal BLLs and low birth weight (LBW, &lt;2500 g), and preterm birth (&lt;37 weeks of gestation).</div></div><div><h3>Results</h3><div>Each 1 μg/dL increase in maternal BLL was associated with a mean reduction of 5g in birthweight (β = −5.02, 95% CI: [-9.05 to −0.99]). No association was observed between BLLs and LBW or preterm birth.</div></div><div><h3>Conclusion</h3><div>Higher maternal BLLs were associated with lower birthweight. However, no significant relationship was observed between maternal BLLs, LBW and preterm birth.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"275 ","pages":"Article 114825"},"PeriodicalIF":4.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review of human developmental health effects following exposure to polychlorinated biphenyl mixtures in early life 早期接触多氯联苯混合物对人类发育健康影响的系统评价。
IF 4.4 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-04-01 Epub Date: 2026-02-16 DOI: 10.1016/j.ijheh.2026.114759
Krista Y. Christensen , John D. Meeker , Geniece M. Lehmann
{"title":"Systematic review of human developmental health effects following exposure to polychlorinated biphenyl mixtures in early life","authors":"Krista Y. Christensen ,&nbsp;John D. Meeker ,&nbsp;Geniece M. Lehmann","doi":"10.1016/j.ijheh.2026.114759","DOIUrl":"10.1016/j.ijheh.2026.114759","url":null,"abstract":"<div><div>Polychlorinated biphenyls (PCBs) are a class of persistent environmental pollutants that exist in the environment as complex mixtures linked to a variety of adverse health effects. This review compiles and organizes human studies of selected health endpoints (early life size and growth; offspring mortality; birth defects) following developmental exposure to PCB mixtures to identify areas of robust research, as well as areas of uncertainty and research needs. We developed a Population, Exposures, Comparators, and Outcomes (PECO) statement to direct the literature search, screening, and study evaluation. We identified n = 154 relevant studies, the majority of which focused on birth weight or other aspects of early life size and growth, with fewer studies evaluating size and growth into adolescence or adulthood. These studies often reported decrements in size at birth associated with higher maternal measures of exposure, although the evidence was less clear for size and growth in later childhood. There were fewer human studies of pregnancy loss or birth defects, and the evidence was generally less consistent for these outcomes.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"273 ","pages":"Article 114759"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bidirectional transfer of influenza virus between hands and environmental surfaces under multifactorial conditions 在多因素条件下,流感病毒在手和环境表面之间的双向转移。
IF 4.4 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-04-01 Epub Date: 2026-02-22 DOI: 10.1016/j.ijheh.2026.114766
Nan Zhang , Baotian Chang , Ruizhen Lin , Xian Lin , Jialuo Tang , Shenglan Xiao
{"title":"Bidirectional transfer of influenza virus between hands and environmental surfaces under multifactorial conditions","authors":"Nan Zhang ,&nbsp;Baotian Chang ,&nbsp;Ruizhen Lin ,&nbsp;Xian Lin ,&nbsp;Jialuo Tang ,&nbsp;Shenglan Xiao","doi":"10.1016/j.ijheh.2026.114766","DOIUrl":"10.1016/j.ijheh.2026.114766","url":null,"abstract":"<div><div>Influenza viruses continue to circulate worldwide, posing persistent challenges to public health. Indirect contact transmission (i.e., transmission via contaminated surfaces, or fomites) is a recognized pathway for influenza spread and depends on multiple factors governing virus transfer between hands and fomites. However, current studies on the determinants of influenza virus transfer rates remain limited in scope and integration. This study quantified, using reverse transcription quantitative PCR (RT-qPCR), the transfer of influenza A virus genomic RNA between hands and surfaces (fomites) under the combined effects of multiple factors. A total of 74 transfer experiments encompassing 444 individual transfer events were conducted using artificial skin. Statistical analyses were performed to evaluate how material type, contact direction, contact force, and environmental conditions influence the transfer of viral RNA. The results demonstrated significant differences in transfer rates among surface materials on horizontal planes (<em>P</em> &lt; 0.001), and a pronounced directional effect (<em>P</em> &lt; 0.001). In contrast, contact force (<em>P</em> = 0.313) and environmental conditions (<em>P</em> = 0.564) showed no statistically significant overall effects. These findings highlight the importance of differentiated disinfection strategies considering surface orientation. Moreover, this study provides refined estimates of viral RNA transfer parameters that quantify hand–fomite transfer, supporting quantitative exposure assessment and informing evidence-based environmental cleaning and hand-hygiene strategies.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"273 ","pages":"Article 114766"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Prenatal ambient heat exposure and neurodevelopment: A scoping review of human and animal research” [Int. J. Hyg Environ. Health 272 (March 2026) 114741] “产前环境热暴露和神经发育:人类和动物研究的范围审查”的勘误表[Int.]J.环境卫生。健康272(三月2026)114741]。
IF 4.4 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-04-01 Epub Date: 2026-01-29 DOI: 10.1016/j.ijheh.2026.114747
Amina Rhaman , Danielle J. Russell , Leaf R. Kardol , Ebony Quintrell , Shannon Morgan , Candra Maung , Azmain Talukder , Aster Gebremedhin , Stephanie Tan , Ramya Padmavathy Radha Krishnan , Erin Kelty , Caitlin Wyrwoll
{"title":"Corrigendum to “Prenatal ambient heat exposure and neurodevelopment: A scoping review of human and animal research” [Int. J. Hyg Environ. Health 272 (March 2026) 114741]","authors":"Amina Rhaman ,&nbsp;Danielle J. Russell ,&nbsp;Leaf R. Kardol ,&nbsp;Ebony Quintrell ,&nbsp;Shannon Morgan ,&nbsp;Candra Maung ,&nbsp;Azmain Talukder ,&nbsp;Aster Gebremedhin ,&nbsp;Stephanie Tan ,&nbsp;Ramya Padmavathy Radha Krishnan ,&nbsp;Erin Kelty ,&nbsp;Caitlin Wyrwoll","doi":"10.1016/j.ijheh.2026.114747","DOIUrl":"10.1016/j.ijheh.2026.114747","url":null,"abstract":"","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"273 ","pages":"Article 114747"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sector-specific ambient air pollution and biomarkers of liver injury. Findings of a cross-sectional population-based survey 特定行业的环境空气污染和肝损伤的生物标志物。一项基于人口的横断面调查的结果
IF 4.4 2区 医学
International journal of hygiene and environmental health Pub Date : 2026-04-01 Epub Date: 2026-02-11 DOI: 10.1016/j.ijheh.2026.114757
Robert Dales , Jessica Evans , Kimberly Mitchell , Mathieu Rouleau , Sabit Cakmak
{"title":"Sector-specific ambient air pollution and biomarkers of liver injury. Findings of a cross-sectional population-based survey","authors":"Robert Dales ,&nbsp;Jessica Evans ,&nbsp;Kimberly Mitchell ,&nbsp;Mathieu Rouleau ,&nbsp;Sabit Cakmak","doi":"10.1016/j.ijheh.2026.114757","DOIUrl":"10.1016/j.ijheh.2026.114757","url":null,"abstract":"<div><h3>Background</h3><div>Ambient air pollution has been linked to biomarkers of liver injury. Little information exists on these effects at relatively low air pollution levels and among children. The relative hepatic toxicity of air pollution mixes from specific emission sectors has not been previously investigated.</div></div><div><h3>Objectives</h3><div>To test associations between sector-specific air pollution (SSAP) and biomarkers of liver injury.</div></div><div><h3>Methods</h3><div>Using generalized linear mixed models, we tested associations between SSAP exposure and liver injury biomarkers in 30,781 participants aged 3-79 years, in the nationally representative Canadian Health Measures Survey (2007 and 2019) who were exposed to relatively low air pollution concentrations.</div></div><div><h3>Results</h3><div>Interquartile range (IQR) increases in SSAP from residential (RES), on- and off-road transportation (ONRD, OFRD), air-marine-rail (AMR), upstream and downstream oil and gas production (UPOG, DNOG), chemical manufacturing (MAN) and pulp and paper (P&amp;P) sectors were associated with significant increases in bilirubin (BIL), alanine aminotransferase (ALT), and aspartate aminotransferase (AST). The largest effects were for alkaline phosphatase with increases of 1.86% (95% CI 0.46,3.26), and 1.58% (95% 0.08, 3.07) for AMR, and DNOG-attributable concentrations, respectively. Among children &lt;13 years, BIL, AST and gamma-glutamyl transferase were positively and significantly associated with all sources, with the largest effect being a 0.8% increase in BIL per IQR increase in UPOG.</div></div><div><h3>Conclusion</h3><div>The relatively low levels of SSAP in Canada were associated with significant increases in liver injury biomarkers, including among children. These observed effects may be consequential given the widespread population exposure especially in countries with higher levels of air pollution.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"273 ","pages":"Article 114757"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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