Lita Kim , Da-An Huh , Kangyeon Park , Jiyoun Lee , Se-Hyun Hwang , Hyeon Jeong Choi , Woohyun Lim , Kyong Whan Moon
{"title":"Dietary exposure to environmental phenols and phthalates in Korean adults: data analysis of the Korean National Environmental Health Survey (KoNEHS) 2018–2020","authors":"Lita Kim , Da-An Huh , Kangyeon Park , Jiyoun Lee , Se-Hyun Hwang , Hyeon Jeong Choi , Woohyun Lim , Kyong Whan Moon","doi":"10.1016/j.ijheh.2025.114597","DOIUrl":"10.1016/j.ijheh.2025.114597","url":null,"abstract":"<div><div>Environmental phenols and phthalates, endocrine-disrupting chemicals, are linked to dietary intake, highlighting the need to identify sources to prevent exposure-related diseases. This study investigates dietary patterns associated with urinary concentrations of environmental phenols and phthalate metabolites in Korean adults using data from 4201 adults in the Korean National Environmental Health Survey Cycle 4 (2018–2020). Exploratory factor analysis identified three dietary patterns: Western-style, traditional Korean, and seafood-rich. We analyzed metabolites with a ≥80 % detection rate, specifically environmental phenols (BPA, BPF, BPS, TCS, MP, EP, BP) and phthalates (MEHHP, MEOHP, MnBP, MECPP, MBzP, MCPP, MEP, MMP). The Western-style or processed food diet showed a significant negative association with MP (β [95 % CI] = −0.14 [−0.24, −0.03]), but no positive association. The traditional Korean diet showed significant positive associations with TCS (β [95 % CI] = 0.09 [0.02, 0.15]), EP (β [95 % CI] = 0.08 [0.01, 0.16]), BP (β [95 % CI] = 0.09 [0.05, 0.12]), MEHHP (β [95 % CI] = 0.04 [0.003, 0.08]), MECPP (β [95 % CI] = 0.06 [0.02, 0.09]), and MMP (β [95 % CI] = 0.11 [0.06, 0.15]). In comparison, it had a significant negative association with BPS (β [95 % CI] = −0.15 [−0.22, −0.09]). The seafood-rich dietary pattern exhibited a significant negative association with BP (β [95 % CI] = −0.07 [−0.11, −0.03]). Certain dietary patterns, including those traditionally regarded as healthy, may be associated with exposure to environmental phenols and phthalates, highlighting the need for further research to understand dietary sources of exposure before drawing implications for public health guidance.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114597"},"PeriodicalIF":4.5,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144084251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siqi Ai , Dongjing Zhang , Jingyuan Cao , Jianyong Lu , Liecheng Hong , Haiyan He , Xiaotao Zhou
{"title":"Assessing the association between prenatal ambient temperature and extreme low birth weight in South Asia","authors":"Siqi Ai , Dongjing Zhang , Jingyuan Cao , Jianyong Lu , Liecheng Hong , Haiyan He , Xiaotao Zhou","doi":"10.1016/j.ijheh.2025.114593","DOIUrl":"10.1016/j.ijheh.2025.114593","url":null,"abstract":"<div><h3>Background</h3><div>Previous studies have suggested the negative effects of exposure to high temperature during pregnancy on multiple adverse birth outcomes. However, there is a lack of evidence regarding the exposure-response relationship and future risk projections for extreme low birth weight (ELBW) in South Asia.</div></div><div><h3>Methods</h3><div>A total of 393,530 pregnant women from Bangladesh, India, Nepal, and Pakistan were included in this analysis. Annual mean temperature throughout each woman's entire gestational period was estimated from the fifth generation of the European Re-Analysis Land Dataset (ERA5-land). We employed the multivariable mixed effect regression model, incorporating random effects for survey strata, to assess the relationship between temperature and ELBW.</div></div><div><h3>Results</h3><div>Stepwise regression models show robust and monotonically varying exposure-response relationships. In the fully adjusted model, for every 1 °C increase in temperature, the risk of ELBW may increase by 1.41 % (95 % CI: 0.99 %, 1.85 %), while birth weight may decrease by −2.26 g (95 % CI: 3.47, −1.04). We found that 2.25 % (95 % CI: 1.26 %, 3.25 %) of ELBW risk can be attributed to annual mean temperature in South Asia, with India having the highest attributed risk (AF = 3.01 %, 95 % CI: 2.48 %, 3.53 %), followed by Bangladesh (AF = 2.81 %, 95 % CI: 2.32 %, 3.29 %). Several environmental, maternal, and household factors may modify the relationship between ambient temperature and ELBW. The risk of ELBW related to temperature rise would increase in the future, especially under the unrestricted emission scenario (e.g. SSP585).</div></div><div><h3>Conclusions</h3><div>In South Asia, greater risks and burdens of ELBW were observed with increasing prenatal ambient temperature. A deeper understanding of covariant factors and intervention measures were needed to address maternal and child health issues under climate change.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114593"},"PeriodicalIF":4.5,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144072561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hiroaki Tomoi , Bonface Butichi Ingumba , Sheillah Simiyu , Evelyne Otteng , James Osewe , Hamilton Majiwa , Laura Braun , Oliver Cumming , Taeko Moriyasu
{"title":"Barriers and enablers for group-based manual emptying services for onsite sanitation facilities in Nairobi, Kenya: a qualitative study","authors":"Hiroaki Tomoi , Bonface Butichi Ingumba , Sheillah Simiyu , Evelyne Otteng , James Osewe , Hamilton Majiwa , Laura Braun , Oliver Cumming , Taeko Moriyasu","doi":"10.1016/j.ijheh.2025.114595","DOIUrl":"10.1016/j.ijheh.2025.114595","url":null,"abstract":"<div><div>Onsite sanitation, such as pit latrines, is essential to achieving universal access to safe sanitation, as outlined in Sustainable Development Goal target 6.2. However, manual emptying for pit latrines in low-income areas is often unhygienic, posing health and environmental risks. Enhancing the safety of these services increases costs, yet affordability for customers is essential. Thus, reducing service costs is a key priority. Group-based approach, where emptiers visit multiple toilets consecutively, has potential to improve both service efficiency and affordability. However, few studies have investigated its applicability to manual emptying. This paper aims to identify barriers and enablers for group-based manual emptying services in low-income neighbourhoods of Nairobi. We conducted 12 focus group discussions with landlords, tenants, and manual emptiers in the Korogocho informal settlement in Nairobi and interviewed 20 key informants from relevant sectors in Kenya. We identified five categories of barriers and enablers that affected general and group-based manual emptying: 1) funding, 2) expertise and equipment, 3) social and commercial habits, 4) physical conditions, and 5) regulatory systems. Of these, a norm that pits are not emptied until they get full, operating time constraints, fair and transparent pricing, and an organiser who can arrange group-based emptying from Category 3, and transport capacity from Category 4 specifically affected group-based manual emptying. Given that the barriers have a cascade structure, addressing some primary barriers such as capacity building and recognising manual emptiers’ role in the sanitation policies could be effective ways to ensure safe and affordable emptying services.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114595"},"PeriodicalIF":4.5,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144070950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between working conditions, vehicle factors, and work-related musculoskeletal disorders affecting job satisfaction and job stress among motorcycle food delivery riders","authors":"Jinjuta Panumasvivat , Vithawat Surawattanasakul , Siriaran Kwangsukstith , Chollada Mahakkanukrauh , Wuttipat Kiratipaisarl","doi":"10.1016/j.ijheh.2025.114594","DOIUrl":"10.1016/j.ijheh.2025.114594","url":null,"abstract":"<div><div>The use of motorcycle food delivery riders (MFDRs) has surged since the COVID-19 pandemic. This study investigates the prevalence of work-related musculoskeletal disorders (WRMSDs) and associated factors among MFDRs in Chiang Mai, Thailand, through a cross-sectional, self-reported online survey conducted from November 2021 to February 2022. The survey included 454 participants, primarily single, male, non-smokers, working over a year, and performing static, repetitive tasks during day shifts. The most common WRMSDs reported over the past 12 months and as new-onset conditions were neck, lower back, and shoulder pain, with pain scores ranging from 4.6 to 6.6. Over half of the participants noted worsening symptoms compared to their previous occupations. Significant factors associated with WRMSDs included working hours, awkward posture, repetitive movements, and age. Each additional working hour per week increased the risk of pain in the neck, shoulder, upper back, and thigh regions (adjusted odd ratio (aOR) 1.02–1.03). Awkward posture was linked to neck, shoulder, upper back, and lower back pain (aOR 1.64–2.38). Repetitive movements correlated with shoulder, wrist, and elbow pain (aOR 2.11–3.16). Vehicle-related factors such as engine capacity >110 cc and larger delivery bags were associated with wrist pain (aOR 1.94–2.12), while clutch gear use was linked to knee and ankle pain (aOR 2.00 and 1.79). These findings highlight the need for ergonomic motorcycle interventions, rider posture training, lumbar support, and work condition improvements to reduce WRMSDs among MFDRs.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114594"},"PeriodicalIF":4.5,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael M. Borghese , Jingxue Feng , Chun Lei Liang , Natasha Kienapple , Katherine E. Manz , Mandy Fisher , Tye E. Arbuckle , Ella Atlas , Joseph M. Braun , Maryse F. Bouchard , Warren Foster , Jillian Ashley-Martin
{"title":"Legacy, alternative, and precursor PFAS and associations with lipids and liver function biomarkers: results from a cross-sectional analysis of adult females in the MIREC-ENDO study","authors":"Michael M. Borghese , Jingxue Feng , Chun Lei Liang , Natasha Kienapple , Katherine E. Manz , Mandy Fisher , Tye E. Arbuckle , Ella Atlas , Joseph M. Braun , Maryse F. Bouchard , Warren Foster , Jillian Ashley-Martin","doi":"10.1016/j.ijheh.2025.114592","DOIUrl":"10.1016/j.ijheh.2025.114592","url":null,"abstract":"<div><h3>Background</h3><div>Legacy per- and polyfluoroalkyl substances (PFAS) can promote dyslipidemia; however, evidence is lacking for alternative and precursor PFAS. We investigated associations between serum concentrations of 31 PFAS and concurrently measured lipids and liver function biomarkers.</div></div><div><h3>Methods</h3><div>PFAS, lipids, and liver function biomarkers were analyzed in serum samples provided by 282 adult females participating in a 2018–2021 follow-up study of a Canadian pregnancy cohort. We examined percent differences in outcomes continuously for 17 PFAS with >50% detection and as detected vs. not detected for 14 PFAS with 10–50% detection. We also examined associations with the sum of 7 PFAS recommended by the National Academies of Sciences, Engineering, and Medicine guidance report on PFAS testing and 17 PFAS. We used weighted quantile sum (WQS) and quantile g-computation models to estimate joint associations.</div></div><div><h3>Results</h3><div>Each two-fold increase in concentrations of PFHxS, PFOS, PFNA, PFDA, PFHpS, and Σ7PFAS were associated with up to 7% higher total and LDL cholesterol and the TC:HDL ratio. Individuals with detectable concentrations of N-EtFOSA, N-MeFOSA, PFBS, and 9Cl-PF3ONS had up to 17% higher total and LDL cholesterol and TC:HDL. Each one-quartile increase in the mixture of 7 PFAS was associated with up to 10% higher total and LDL cholesterol. Adding additional PFAS to the mixture (17 PFAS) made estimates less precise in WQS models and attenuated associations to the null in quantile g-computation models.</div></div><div><h3>Conclusion</h3><div>Alternative and precursor PFAS, including replacements for legacy PFAS, are associated with higher cholesterol levels; prospective studies are required to confirm these findings.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114592"},"PeriodicalIF":4.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miguel Santibáñez , Juan José Ruiz-Cubillán , Juan Agüero , Andrea Expósito , Beatriz Abascal , Juan Luis García-Rivero , Carlos Antonio Amado , Maria Mercedes Hernando , Laura Ruiz-Azcona , Esther Barreiro , Adriana Núñez-Robainas , José Manuel Cifrián , Ignacio Fernandez-Olmo
{"title":"Personal exposure to particulate matter oxidative potential and airway inflammation: differences between asthmatic and non-asthmatic adults","authors":"Miguel Santibáñez , Juan José Ruiz-Cubillán , Juan Agüero , Andrea Expósito , Beatriz Abascal , Juan Luis García-Rivero , Carlos Antonio Amado , Maria Mercedes Hernando , Laura Ruiz-Azcona , Esther Barreiro , Adriana Núñez-Robainas , José Manuel Cifrián , Ignacio Fernandez-Olmo","doi":"10.1016/j.ijheh.2025.114589","DOIUrl":"10.1016/j.ijheh.2025.114589","url":null,"abstract":"<div><div>We aimed to determine whether exposure to particulate matter PM, measured as the oxidative potential (OP) of filters collected from 24 h personal samplers, is associated with increased airway inflammation in asthmatic and non-asthmatic volunteers. Forty-two adult asthmatic patients (25 women and 17 men) and 37 matched controls wore a personal sampler for a day collecting fine (PM2.5) and coarse (PM10–2.5) particles, and determining 24 h afterwards their fractional exhaled nitric oxide (FeNO). The PM-OP was determined by two methods: dithiothreitol (DTT) and ascorbic acid (AA) being OP levels dichotomized based on the median, to calculate adjusted mean differences (aMDs) and odds ratios (aORs) with sex, age, study level, body mass index and interleukin-6 (IL-6) levels as confounders. Statistically significant associations between PM-OP and FeNO levels in non-asthmatic volunteers were observed: aMD for OP-DTT PM2.5 = 11.64 ppbs; 95 %CI (0.13–22.79); aMD for OP-AA PM10–2.5 = 15.67; 95 %CI (2.91–28.43) with aORs = 4.87 and 18.18 respectively. In asthmatic patients an association was also observed in the form of aORs, but of lower magnitude (1.91 and 1.94 respectively). Non-significant higher FeNO levels (aMD = 5.22) and an aOR = 3.92 were also observed in non-asthmatic volunteers for OP-AA in the fine fraction. As a conclusion, the effect of personal PM-OP on airway inflammation appears to be differential between asthmatic and non-asthmatic volunteers suggesting a potential implication of inhaled corticosteroids diminishing the reactivity of airway epithelium since adjusted associations were higher in volunteers without asthma.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114589"},"PeriodicalIF":4.5,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daisuke Kurogochi , Kohei Hasegawa , Yuji Inaba , Takumi Shibazaki , Miyuki Iwai-Shimada , Shin Yamazaki , Michihiro Kamijima , Teruomi Tsukahara , Tetsuo Nomiyama , the Japan Environment and Children's Study (JECS) Group
{"title":"Prenatal mercury exposure and body mass index at 2 and 4 years: The Japan Environment and Children's Study","authors":"Daisuke Kurogochi , Kohei Hasegawa , Yuji Inaba , Takumi Shibazaki , Miyuki Iwai-Shimada , Shin Yamazaki , Michihiro Kamijima , Teruomi Tsukahara , Tetsuo Nomiyama , the Japan Environment and Children's Study (JECS) Group","doi":"10.1016/j.ijheh.2025.114566","DOIUrl":"10.1016/j.ijheh.2025.114566","url":null,"abstract":"<div><div>Whether prenatal mercury (Hg) exposure may increase obesity among children remains unclear. We here investigated the association between cord blood methylmercury (MeHg) and inorganic mercury (IHg) concentration and body mass index (BMI) z-scores, as well as overweight or obesity at the ages of 2 and 4 years.</div><div>We used 3147 mother–child pairs data from the Japan Environment and Children's Study. The levels of MeHg and IHg in cord blood were quantified by liquid chromatography coupled with inductively coupled plasma mass spectrometry. Pediatric physicians examined the children's height and weight at ages 2 and 4, and BMI z-scores were calculated. Linear or logistic regression models were employed to examine the association between Hg concentrations and BMI outcomes.</div><div>After adjusting for potential confounders, our findings indicated that a 2-fold increase in IHg concentrations was associated with increases in BMI z-scores of 0.05 (95% CI: 0.01, 0.09; p = 0.021) and 0.05 (95% CI: 0.02, 0.09; p = 0.0046) at ages 2 and 4, respectively. Conversely, no significant associations were observed for MeHg. When overweight or obesity was employed as an outcome, we did not observe consistent associations for either MeHg or IHg.</div><div>In this birth cohort study, an increase in cord blood IHg, but not MeHg, was associated with a slight increase in BMI z-score in children at 2 and 4 years of age. However, the observed associations were weak and inconsistent, suggesting that the results might be due to residual confounding or mere chance rather than indicative of a causal relationship.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114566"},"PeriodicalIF":4.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mary E. Spitzer , Yoonhee Jung , Jonathan D. Sexton , Amanda M. Wilson , J. Lance Picton , Brandon Toshio Miura-Akagi , Carolyn Buckley , Sophie E. Upson , Lisa M. Ackerley , Lucas Gent , Adrian C. Paskey , Stephanie Cooper , Kelly A. Reynolds
{"title":"Quantifying fomite hotspots and targeted hygiene impacts in a hotel lobby","authors":"Mary E. Spitzer , Yoonhee Jung , Jonathan D. Sexton , Amanda M. Wilson , J. Lance Picton , Brandon Toshio Miura-Akagi , Carolyn Buckley , Sophie E. Upson , Lisa M. Ackerley , Lucas Gent , Adrian C. Paskey , Stephanie Cooper , Kelly A. Reynolds","doi":"10.1016/j.ijheh.2025.114586","DOIUrl":"10.1016/j.ijheh.2025.114586","url":null,"abstract":"<div><div>Environmental surfaces in public settings serve as reservoirs for microbial pathogens, including norovirus, rhinovirus, and adenovirus, which can persist and spread through hand-to-fomite contact. Despite limited evidence of SARS-CoV-2 fomite transmission, hygiene protocols were widely intensified during the pandemic. This study evaluates viral spread and infection risks in a hotel lobby and assesses the efficacy of a Targeted Hygiene intervention designed to reduce contamination while minimizing excessive chemical use. A viral tracer study, using bacteriophage Phi X174, and human behavior observations were utilized to monitor surface contamination patterns, followed by Quantitative Microbial Risk Assessment (QMRA) to estimate infection probabilities. Tracer organisms seeded on high-touch surfaces spread to 50 % of sampled fomites within 4 h. A subsequent Targeted Hygiene intervention, using disinfecting wipes, sprays, or aerosols tailored to surface types, resulted in a statistically significant 97.36 % reduction in viral concentrations (1.57 log<sub>10</sub> reduction, p < 0.0001). The proportion of cross-contaminated surfaces (i.e., non-seeded sites testing positive) decreased from 13 % to 2 %, and the overall percentage of positive surfaces dropped from 50 % to 42 %. QMRA modeling demonstrated that infection risks from a single fomite-hand-face contact were highest for rhinovirus, rotavirus, and adenovirus. Following intervention, infection risk was reduced by over 97 % for all modeled pathogens. Risk levels for all viruses and bacteria met the U.S. EPA and WHO benchmark of less than 1 infection per 10,000 exposures used in drinking water guidelines. Notably, bacterial infection risks, already low pre-intervention, were further reduced to meet the more stringent 1 infection per 1,000,000 risk threshold. This is the first study to integrate real-world human behavior, viral tracer data, and QMRA modeling to assess Targeted Hygiene in a hospitality setting. Findings support the implementation of evidence-based hygiene protocols that prioritize high-risk surfaces and timing, offering a sustainable approach to reducing infection risks in public environments.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114586"},"PeriodicalIF":4.5,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrien A. Wilkie , Alison K. Krajewski , Fanny Njie , Kevin Park , Sarah Zelasky , Kristen M. Rappazzo , Thomas J. Luben
{"title":"Long-term exposure to criteria air pollutants and infant mortality: a systematic review and meta-analysis","authors":"Adrien A. Wilkie , Alison K. Krajewski , Fanny Njie , Kevin Park , Sarah Zelasky , Kristen M. Rappazzo , Thomas J. Luben","doi":"10.1016/j.ijheh.2025.114587","DOIUrl":"10.1016/j.ijheh.2025.114587","url":null,"abstract":"<div><h3>Aim</h3><div>We conducted a systematic review/meta-analysis for epidemiologic evidence of the association between long-term criteria air pollution (nitrogen dioxide (NO<sub>2</sub>), sulfur dioxide (SO<sub>2</sub>), coarse particulate matter (PM<sub>10</sub>), fine particulate matter (PM<sub>2.5</sub>), ozone (O<sub>3</sub>), carbon monoxide (CO)) exposure and all-cause, respiratory, and sudden infant death syndrome (SIDS) infant mortality.</div></div><div><h3>Methods</h3><div>Studies were identified through PubMed/Web of Science databases using comprehensive search terms, then screened using predefined criteria. For studies eligible for inclusion in meta-analyses, we applied a systematic rubric for evaluating study quality across domains: participant selection, outcome, exposure, confounding, analysis, selective reporting, sensitivity, overall quality. When ≥3 eligible studies provided effect estimates, we performed meta-analyses to estimate pooled odds ratios (ORs) and 95% confidence intervals (95% CI) for air pollutants and infant mortality.</div></div><div><h3>Results</h3><div>Of the 701 initial studies, we excluded 678 studies in the abstract screening and full text screening phases, leaving 23 studies for inclusion. Four studies included extractable effect estimates for PM<sub>10</sub> and seven for PM<sub>2.5</sub>. We could not conduct meta-analyses for CO, O<sub>3</sub>, NO<sub>2</sub>, or SO<sub>2</sub> because each had <3 eligible studies. The pooled OR (95% CI) for a 10-μg/m<sup>3</sup> increase in PM<sub>10</sub> concentration was 1.04 (1.02, 1.06) for all-cause, 1.11 (1.02, 1.21) for respiratory, and 1.05 (0.98, 1.13) for SIDS infant mortality. The pooled OR for a 5-μg/m<sup>3</sup> increase in PM<sub>2.5</sub> concentration was 1.02 (0.98, 1.05) for all-cause, 0.83 (0.30, 2.27) for respiratory, and 0.97 (0.88, 1.08) for SIDS infant mortality.</div></div><div><h3>Conclusions</h3><div>Long-term exposure to PM<sub>10</sub> is associated with all-cause and respiratory infant mortality across studies.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114587"},"PeriodicalIF":4.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new approach for simultaneous measurement of aerosol respiratory deposition and its chemical composition: Health risk assessment of metal engineered nanomaterials in consumer spray aerosols","authors":"Jinho Lee , Wei-Chung Su","doi":"10.1016/j.ijheh.2025.114588","DOIUrl":"10.1016/j.ijheh.2025.114588","url":null,"abstract":"<div><h3>Background</h3><div>Conventional methods for studying aerosol deposition face limitations when applied to aerosols with irregular shapes and diverse physical properties.</div></div><div><h3>Objective</h3><div>This study aimed to develop the MALDA (Mobile Aerosol Lung Deposition Apparatus)-MOUDI tandem system to simultaneously estimate the size-specific deposition fraction of aerosols and their chemical constituents. Using this innovative approach, we investigated the respiratory deposition of aerosols generated from selected consumer spray products and evaluated the inhalation risks of engineered nanomaterials (ENMs), specifically metals, in these aerosols.</div></div><div><h3>Methods</h3><div>Aerosols were generated from two common types of consumer spray products—trigger and propellant sprays. The size-segregated respiratory deposition fraction and mass proportions of target metals in the aerosols were measured. Occupational exposure scenarios were then designed to estimate the non-cancer and cancer risks associated with inhalation of ENMs (metals) in these aerosols.</div></div><div><h3>Results</h3><div>The MALDA-MOUDI tandem system was successfully developed and validated. Results demonstrated that the non-cancer and cancer risks of inhaled metals due to occupational exposure to the target spray aerosols were below established safety thresholds.</div></div><div><h3>Significance</h3><div>The MALDA-MOUDI tandem system provides an innovative and systematic approach to assess size-specific aerosol deposition in major human airway regions. This method can be applied to broader environmental and occupational aerosol exposure research to evaluate health risks from toxic substances in aerosols. Findings from this study also offer valuable insights for environmental and occupational health research and propose an improved method for health risk assessment.</div></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"267 ","pages":"Article 114588"},"PeriodicalIF":4.5,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}