International journal of hygiene and environmental health最新文献

{"title":"Post-war status of water supply, sanitation, hygiene and related reported diseases in Tigray, Ethiopia: A community-based cross-sectional study","authors":"Akeza Awealom Asgedom ,&nbsp;Gebru Hailu Redae ,&nbsp;Hailay Gebretnsae ,&nbsp;Mengistu Hagazi Tequare ,&nbsp;Hagos Degefa Hidru ,&nbsp;Gebregziabher Berihu Gebrekidan ,&nbsp;Abadi Kidanemariam Berhe ,&nbsp;Mohamedawel Mohamedniguss Ebrahim ,&nbsp;Mulugeta Cherinet ,&nbsp;Gebremedhin Gebreegziabher Gebretsadik ,&nbsp;Haftom Gebrehiwot Woldearegay ,&nbsp;Yemane Berhane Tesfau ,&nbsp;Tedros Bereket ,&nbsp;Muzey Gebremichael Berhe ,&nbsp;Meresa Gebremedhin Weldu ,&nbsp;Gebrekiros Gebremichael Meles ,&nbsp;Micheale Hagos Debesay ,&nbsp;Rieye Esayas ,&nbsp;Mache Tsadik","doi":"10.1016/j.ijheh.2024.114460","DOIUrl":"10.1016/j.ijheh.2024.114460","url":null,"abstract":"<div><p>Water, sanitation and hygiene (WASH) associated diseases remain a global public health issue and linked with Sustainable Development Goal 6. In November 2020, a war broke out in Tigray, Ethiopia, resulting in a negative health consequence. The post war status of WASH and its associated diseases are not documented. The aim of this study was to assess the status of drinking water, sanitation and hygiene practices and the prevalence of WASH-associated diseases in Tigray, Ethiopia following the war. A community-based cross-sectional study was conducted in 24 randomly selected accessible districts of Tigray, Ethiopia. A standardized questionnaire was used to collect data from households in the study. Data was collected from 2338 households. Descriptive statistics and binary logistic regression were used to analyze the data. The average age of respondents was 28.7 years (SD = 6.2). The majority of respondents 2030 (86.8%) were married and 1698 (72.6%) were rural residents. Nearly one third of the respondents were uneducated and around 40% have either radio or TV as means of communication. More than half (55.2%) of the respondents had a family size of over 5.</p><p>A quarter (25%, 95% CI: 23.3, 26.8) of study participants had access to a basic water supply. Less than a tenth (7.7%, 95% CI: 6.6, 8.8) of households had access to basic sanitation. Basic hand washing was available in 2% of households. Malaria, diarrhoea, skin infection and eye infection were the common reported disease in the community. Marital status, family size, place of residence and liquid waste management were the most important predictors of reported diseases.</p><p>Access to basic water, sanitation and hygiene services was low, and the prevalence of malaria, diarrhoea and skin infections was higher. There were differences in WASH services and reported diseases according to zone and place of residence (urban-rural). Post war, improved access to basic water, sanitation and hygiene services is recommended to prevent WASH-associated diseases in Tigray, Ethiopia. Furthermore, the prevention oriented policy of the country needs better implementation to reduce preventable diseases and ensure better health status in the community.</p></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"263 ","pages":"Article 114460"},"PeriodicalIF":4.5,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal and early life exposure to fine particulate matter and telomere length in early childhood","authors":"Jesephat Edzie ,&nbsp;Cecilia Alcala ,&nbsp;Tessa R. Bloomquist ,&nbsp;Ivan Gutierrez-Avila ,&nbsp;Allan C. Just ,&nbsp;Vishal Midya ,&nbsp;Martha María Téllez Rojo ,&nbsp;Guadalupe Estrada-Gutierrez ,&nbsp;Rosalind J. Wright ,&nbsp;Robert O. Wright ,&nbsp;Andrea A. Baccarelli ,&nbsp;Maria José Rosa","doi":"10.1016/j.ijheh.2024.114447","DOIUrl":"10.1016/j.ijheh.2024.114447","url":null,"abstract":"<div><h3>Background</h3><p>Telomere length is a biomarker of molecular aging that may be impacted by air pollution exposure starting in utero. We aimed to examine the association between prenatal and early life exposure to fine particulate matter (PM_2.5) and leukocyte telomere length (LTL) in children and explore sex differences.</p></div><div><h3>Methods</h3><p>Analyses included 384 mother–child pairs enrolled in the Programming Research in Obesity, Growth, and Environmental Stressors (PROGRESS) birth cohort in Mexico City. Exposure to PM_2.5 was estimated at the residential level using a satellite based spatio-temporally resolved prediction model. Average relative LTL was measured in DNA isolated from blood collected at age 4–6 years using quantitative real-time polymerase chain reaction. Linear regression models were used to examine the association between average PM_2.5 across pregnancy, individual trimesters, first postnatal year, and LTL. Models were adjusted for maternal age and education at enrollment, prenatal environmental tobacco smoke exposure, child sex, age, and body mass index z-score at LTL measurement. Effect modification by sex was investigated with interaction terms and stratification.</p></div><div><h3>Results</h3><p>In trimester specific models, we found an association between 2nd trimester PM_2.5 and elongated LTL (β: 4.34, 95%CI [0.42, 8.42], per 5 μg/m³ increase). There was suggestive effect modification by sex on average 2nd trimester PM_2.5 with stronger associations seen in females compared to males (β: 7.12, [95%CI: 0.98, 13.6] and β: 1.43 [95%CI: −3.46, 6.57]) per 5 μg/m³ increase respectively.</p></div><div><h3>Conclusion</h3><p>Second trimester PM_2.5 levels were associated with changes in LTL in early childhood. Understanding temporal and sex differences in PM_2.5 exposure may provide insights into telomere dynamics over early life.</p></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"263 ","pages":"Article 114447"},"PeriodicalIF":4.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142167999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Lead exposure by E-waste disposal and recycling in Agbogbloshie, Ghana” [Int. J. Hyg. Environ. Health 259C (2024) 114375]","authors":"P. Püschel ,&nbsp;K.M. Agbeko ,&nbsp;A.A. Amoabeng-Nti ,&nbsp;J. Arko-Mensah ,&nbsp;J. Bertram ,&nbsp;J.N. Fobil ,&nbsp;S. Waldschmidt ,&nbsp;K. Löhndorf ,&nbsp;T. Schettgen ,&nbsp;M. Lakemeyer ,&nbsp;A. Morrison ,&nbsp;T. Küpper","doi":"10.1016/j.ijheh.2024.114446","DOIUrl":"10.1016/j.ijheh.2024.114446","url":null,"abstract":"","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114446"},"PeriodicalIF":4.5,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on: Lead exposure by E-waste disposal and recycling in Agbogbloshie, Ghana by Püschel et al. International Journal of Hygiene and Environmental Health 259 (2024)","authors":"A. Kaifie","doi":"10.1016/j.ijheh.2024.114445","DOIUrl":"10.1016/j.ijheh.2024.114445","url":null,"abstract":"","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"264 ","pages":"Article 114445"},"PeriodicalIF":4.5,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary biomarkers of environmental exposures and asthma morbidity in a school inner city asthma study","authors":"Marissa Hauptman ,&nbsp;Medina S. Jackson-Browne ,&nbsp;Stefanie Busgang ,&nbsp;Syam S. Andra ,&nbsp;Marisa A. Patti ,&nbsp;Noelle B. Henderson ,&nbsp;Paul Curtin ,&nbsp;Susan L. Teitelbaum ,&nbsp;Keith Acosta ,&nbsp;Michelle Maciag ,&nbsp;Jonathan M. Gaffin ,&nbsp;Carter R. Petty ,&nbsp;Robert O. Wright ,&nbsp;Diane R. Gold ,&nbsp;Wanda Phipatanakul","doi":"10.1016/j.ijheh.2024.114430","DOIUrl":"10.1016/j.ijheh.2024.114430","url":null,"abstract":"<div><h3>Background</h3><p>The burden of pediatric asthma and other allergic diseases is not evenly distributed among United States populations.</p></div><div><h3>Objective</h3><p>To determine whether urinary biomarkers are associated with asthma morbidity, and if associations vary by child race, ethnicity and sex.</p></div><div><h3>Methods</h3><p>This study includes <em>n</em> = 152 children with physician-diagnosed asthma who participated in the School Inner-City Asthma Intervention Study (SICAS-2). Metabolites of phenol, paraben, polycyclic aromatic hydrocarbons, and phthalate analytes were analyzed from urine samples collected at baseline. Asthma symptom days over the past 2 weeks were dichotomized to no asthma symptom days or any asthma symptom days. Cross-sectional regression models were adjusted for age, sex, number of colds, household income, prescription control, race and ethnicity, body mass index (BMI) percentile, and smoke exposure. Weighted quantile sum regression was used to analyze each chemical class and a total mixture effect, controlling for the same covariates. Analyses were conducted with the assistance of the National Institute of Environmental Health Sciences Children's Health Exposure Analysis Resource (CHEAR).</p></div><div><h3>Results</h3><p>Participants were mostly Hispanic/Latino and low income with an average age of 7.83 years and the average maximum asthma symptom days over the past two weeks of 2.13 (standard deviation: 3.56). The maximum concentrations indicate extreme values for several chemicals, including bisphenol-3, 2,5-dichlorophenol, propyl and methyl parabens, triclosan, methyl paraben and cotinine. We found a significant interaction effect and differing contributions of analytes for children with allergen sensitivity versus those that did not. For stratified analyses assessing effect modification by child race and ethnicity, weighted quantile sum interaction models showed reduced odds of asthma symptoms to a greater magnitude in children of other races and ethnicities compared to Black, Non-Hispanic children.</p></div><div><h3>Conclusions</h3><p>Preliminary analyses of the association between environmental chemical exposure and asthma symptoms among inner-city children revealed an inverse association, which may be due to personal care and medication use and can be understood further in future analyses. Beneficial effects were detected for most of the chemicals.</p></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"262 ","pages":"Article 114430"},"PeriodicalIF":4.5,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142083552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between ambient air pollution a week prior to delivery and preterm birth using a nationwide study in Sweden","authors":"Nabeel Aziz ,&nbsp;Massimo Stafoggia ,&nbsp;Olof Stephansson ,&nbsp;Nathalie Roos ,&nbsp;Sari Kovats ,&nbsp;Matthew Chersich ,&nbsp;Veronique Filippi ,&nbsp;Cherie Part ,&nbsp;Britt Nakstad ,&nbsp;Shakoor Hajat ,&nbsp;Petter Ljungman ,&nbsp;Jeroen de Bont","doi":"10.1016/j.ijheh.2024.114443","DOIUrl":"10.1016/j.ijheh.2024.114443","url":null,"abstract":"<div><h3>Background</h3><p>Air pollution exposure has been linked with increased risk of preterm birth, which is one of the leading causes of infant mortality. Limited studies have attempted to explore these associations in low-polluted areas. In this study, we aimed to assess the association between short-term exposure to ambient air pollution and preterm birth in Sweden.</p></div><div><h3>Method</h3><p>In this population-based study we included preterm births between 2014 and 2019 from the Swedish Pregnancy Register. We applied a spatiotemporal model to estimate daily levels of particulate matter &lt;2.5 μm (PM_2.5), PM &lt; 10 μm (PM₁₀), nitrogen dioxide (NO_2), and ozone (O₃) at the residential address of each participant. We applied a time-stratified case-crossover design with conditional logistic regression analysis to estimate odds ratios (OR) of preterm birth per 10 μg/m³ (PM₁₀, NO₂, O₃) and 5 μg/m³ (PM_2.5) increase in air pollution exposure at 0–6-day lag. Two-pollutant models were applied to evaluate the independent association of each exposure on preterm birth. We also stratified by maternal characteristics to identify potential effect modifiers.</p></div><div><h3>Results</h3><p>28,216 (4.5%) preterm births were included. An increase in O₃ exposure was associated with increased odds of preterm birth [OR = 1.06 per 10 μg/m³ (95% CI, 1.02; 1.10]. PM_2.5 and PM₁₀ were not significantly associated with preterm birth, and NO₂ displayed a negative nonlinear association with preterm birth. We did not observe any notable effect modification, but we found suggestive larger associations between O₃ and preterm birth when stratifying by male sex, spontaneous delivery, and spring season.</p></div><div><h3>Conclusions</h3><p>Increased O₃ exposure one week before delivery was associated with an increased risk of preterm birth in Sweden, a country with levels of air pollution below the current World Health Organization air quality guidelines. Increases in O₃ levels with climate change make these findings especially concerning.</p></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"262 ","pages":"Article 114443"},"PeriodicalIF":4.5,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S143846392400124X/pdfft?md5=d1da12df51d788611e737041cfbd83ea&pid=1-s2.0-S143846392400124X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142002350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temperature, relative humidity and elderly type 2 diabetes mortality: A spatiotemporal analysis in Shandong, China","authors":"Wenxiu Zheng ,&nbsp;Jie Chu ,&nbsp;Hilary Bambrick ,&nbsp;Ning Wang ,&nbsp;Kerrie Mengersen ,&nbsp;Xiaolei Guo ,&nbsp;Wenbiao Hu","doi":"10.1016/j.ijheh.2024.114442","DOIUrl":"10.1016/j.ijheh.2024.114442","url":null,"abstract":"<div><h3>Background</h3><p>The mortality of type 2 diabetes mellitus (T2DM) can be affected by environmental factors. However, few studies have explored the effects of environmental factors across diverse regions over time. Given the vulnerability observed in the elderly group in previous research, this research applied Bayesian spatiotemporal models to assess the associations in the elderly group.</p></div><div><h3>Methods</h3><p>Data on T2DM death in the elderly group (aged over 60 years old) at the county level were collected from the National Death Surveillance System between 1^st January 2013 and 31^st December 2019 in Shandong Province, China. A Bayesian spatiotemporal model was employed with the integrated Nested Laplace Approach to explore the associations between socio-environmental factors (i.e., temperatures, relative humidity, the Normalized Difference Vegetation Index (NDVI), particulate matter with a diameter of 2.5 μm or less (PM_2.5) and gross domestic product (GDP)) and T2DM mortality.</p></div><div><h3>Results</h3><p>T2DM mortality in the elderly group was found to be associated with temperature and relative humidity (i.e., temperature: Relative Risk (RR) = 1.41, 95% Credible Interval (CI): 1.27–1.56; relative humidity: RR = 1.05, 95% CI:1.03–1.06), while no significant associations were found with NDVI, PM_2.5 and GDP. In winter, significant impacts from temperature (RR = 1.18, 95% CI: 1.06–1.32) and relative humidity (RR = 0.94, 95% CI: 0.89–0.99) were found. Structured and unstructured spatial effects, temporal trends and space-time interactions were considered in the model.</p></div><div><h3>Conclusions</h3><p>Higher mean temperatures and relative humidities increased the risk of elderly T2DM mortality in Shandong Province. However, a higher humidity level decreased the T2DM mortality risk in winter in Shandong Province. This research indicated that the spatiotemporal method could be a useful tool to assess the impact of socio-environmental factors on health by combining the spatial and temporal effects.</p></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"262 ","pages":"Article 114442"},"PeriodicalIF":4.5,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1438463924001238/pdfft?md5=e0e2010b677afa38371b310fed9b3388&pid=1-s2.0-S1438463924001238-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141990840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preconception mitochondrial DNA copy number plays a crucial role in linking prenatal air pollution with the risk of preterm birth","authors":"Qiuming Wang ,&nbsp;Yalong Wang ,&nbsp;Panpan Sun ,&nbsp;Yanan He ,&nbsp;Xi Yan ,&nbsp;Lifang Jiang ,&nbsp;Yuting Zeng ,&nbsp;Jingjing Wu ,&nbsp;Junxi Zhang ,&nbsp;CuiPing Wu ,&nbsp;Fangfang Yu ,&nbsp;Yue Ba ,&nbsp;Jian Chai ,&nbsp;Guoyu Zhou","doi":"10.1016/j.ijheh.2024.114441","DOIUrl":"10.1016/j.ijheh.2024.114441","url":null,"abstract":"<div><p>The relationship between maternal peripheral blood mitochondrial DNA and adverse pregnancy outcomes, specifically preterm birth (PTB), remains uncertain. To investigate the effects of preconception mitochondrial DNA copy number (mtDNAcn) on the association between prenatal air pollutants exposure and PTB risk, a total of 1871 expectant mothers from six regions in Henan Province were recruited. Information regarding air pollutants was obtained from 151 environmental monitoring sites, and relative mtDNAcn was evaluated using real-time PCR analysis. After adjusting for potential confounding variables, it was determined that the risk of PTB increased with elevated levels of inhalable particulate matter (PM₁₀), fine particulate matter (PM_2.5), sulfur dioxide (SO₂), carbon monoxide (CO) and ozone (O₃) exposure (<em>P</em> &lt; 0.05) but decreased with higher nitrogen dioxide (NO₂) exposure (0.05 &lt; <em>P</em> &lt; 0.10) during the entire pregnancy. Additionally, the preconception relative mtDNAcn was lower in the PTB group (0.82 ± 0.23) compared to the term group (0.92 ± 0.29). Furthermore, for each 0.1-unit increase in preconception mtDNAcn, the risk of PTB decreased by 14.8%. Stratified analyses revealed that the risk of PTB rose with increasing O₃ concentrations, regardless of the relative mtDNAcn. Moreover, the study found a significant association between PTB risk and prenatal exposure to elevated PM₁₀, PM_2.5, SO₂, and CO, particularly in mothers with low mtDNAcn (≤0.88) (<em>P</em> &lt; 0.05). Conversely, a decrease in the PTB risk was observed with elevated NO₂ exposure in mothers with high mtDNAcn (&gt;0.88). Interaction analysis revealed that exposure to PM₁₀, PM_2.5, SO₂, NO₂, and CO interacted with mtDNAcn, respectively, affecting PTB risk (<em>P</em>_-interaction&lt;0.05). These findings indicate a noteworthy association between PTB risk and prenatal air pollutants exposure, which is influenced by the preconception mtDNAcn.</p></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"262 ","pages":"Article 114441"},"PeriodicalIF":4.5,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical and haematological effects of serum PFOA, ADV and cC6O4 in workers of a chemical company producing fluoropolymers, Italy, 2013–2022","authors":"Dario Consonni ,&nbsp;Silvia Fustinoni","doi":"10.1016/j.ijheh.2024.114440","DOIUrl":"10.1016/j.ijheh.2024.114440","url":null,"abstract":"<div><h3>Introduction</h3><p>Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are widely used in the manufacture of fluoropolymers. We evaluated biochemical and haematological effects of three PFAS, serum perfluorooctanoic acid (PFOA), ADV, and cC₆O₄ in workers of a fluoropolymer company.</p></div><div><h3>Methods</h3><p>Using data (2013–2022), we fitted random intercept regression models adjusted for several covariates and reciprocal adjustment between the three PFAS.</p></div><div><h3>Results</h3><p>We analysed data of 814 workers (698 men, 116 women), 607 from the chemical plant, 207 from the research centre, for a total of 4912 blood samples (2065 with all three PFAS measured). Median levels of PFOA and ADV were 21.3 and 120 μg/L. Most (65.5%) cC₆O₄ measurements were below the limits of quantification (which varied over time from 5 to 0.1 μg/L). For PFOA, we observed positive associations with total cholesterol (+1.1% increase per ln(PFOA) increase) and apolipoprotein B (+1.4%) and negative associations with alkaline phosphatase (−1.5%); suggestive associations were also found with RBC (−0.4%), IgA (−1.5%), IgM (−1.4%). ADV was positively associated with total and LDL cholesterol (+1.0% and +1.6% per ln(ADV) increase), apolipoprotein B (+1.0%), GGT (+2.1%), IgM (+1.4%), and WBC (+1.5%) and negatively associated with direct bilirubin (−2.3%) and alpha-2-globulins (−0.7%); suggestive associations were found for indirect bilirubin (−2.0%), oestradiol (−2.1%), ad CRP (+6.0%). For samples with detectable cC₆O₄ levels we observed higher values of ALP (+2.3%), proteins (+0.5%), IgG (+0.7%) and platelets (+1.6%) and suggestively increased total bilirubin (+3.9%), RBC (+0.6%), and oestradiol (+5.8%). Some associations (total cholesterol, apolipoprotein B, WBC, total bilirubin, and alkaline phosphatase showed reverse time trends in parallel with the strong decrease of serum PFOA and ADV over the study period.</p></div><div><h3>Discussion</h3><p>We found associations of serum PFOA and ADV with lipid metabolism, liver function, and immunoglobulins. The reverse time trends of some endpoints in parallel with decrease of serum PFOA and ADV reinforce causal interpretation of results. cC₆O₄ showed a different pattern of associations.</p></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"262 ","pages":"Article 114440"},"PeriodicalIF":4.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1438463924001214/pdfft?md5=35d89cad3fdc9c42db718226eb561b2b&pid=1-s2.0-S1438463924001214-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141899243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between air temperature and self-perceived health status in Southern Germany: Results from KORA FIT study","authors":"Hasan Sohail ,&nbsp;Siqi Zhang ,&nbsp;Ute Kraus ,&nbsp;Santtu Mikkonen ,&nbsp;Susanne Breitner ,&nbsp;Kathrin Wolf ,&nbsp;Nikolaos Nikolaou ,&nbsp;Annette Peters ,&nbsp;Timo Lanki ,&nbsp;Alexandra Schneider","doi":"10.1016/j.ijheh.2024.114431","DOIUrl":"10.1016/j.ijheh.2024.114431","url":null,"abstract":"<div><h3>Background</h3><p>Short-term exposure to low and high air temperatures can cause serious harmful effects on human health. Existing literature has mostly focused on associations of ambient air temperature with mortality and the need for health care in population-level studies. Studies that have considered self-perceived health status as an outcome when examining the effects of air temperature on health are scarce. In this study, we explored the short-term association of daily mean air temperature with various measures of self-perceived health status.</p></div><div><h3>Methods</h3><p>This cross-sectional analysis is based on the Cooperative Health Research in the Region of Augsburg (KORA) FIT study conducted in 2018/2019 and included participants from the Augsburg region of Southern Germany. Health-related quality of life (HRQOL) was evaluated by using the 5-level EuroQol Five Dimension (EQ-5D-5L) questionnaire, including the EuroQol visual analog scale (EQ-VAS). Self-rated health (SRH) and comparative self-rated health (CSRH) were each assessed using a single question. Daily mean air temperature data was estimated using a spatiotemporal model and assigned to participants' home addresses at a resolution of 1 × 1 km. Regression models with a Distributed Lag Non-linear Modeling (DLNM) approach were used to investigate the associations between daily mean air temperature and self-perceived health measures.</p></div><div><h3>Results</h3><p>We found no association of heat or cold with the HRQOL, SRH or CSRH. Nevertheless, there was a significant protective association of low air temperature with the EQ-5D-5L dimension “usual activities.”</p></div><div><h3>Conclusion</h3><p>There was no evidence of daily mean air temperature adversely affecting participants' self-perceived health status.</p></div>","PeriodicalId":13994,"journal":{"name":"International journal of hygiene and environmental health","volume":"262 ","pages":"Article 114431"},"PeriodicalIF":4.5,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141881500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}