International Journal of Dermatology最新文献

{"title":"Dermatological Care Providers in Samoa: Western Medicine Practitioners and Traditional Healers.","authors":"Sophia Q Xu, Fetaomi Tapu-Qiliho","doi":"10.1111/ijd.70064","DOIUrl":"https://doi.org/10.1111/ijd.70064","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tildrakizumab in Psoriatic Patients With Current or Past Malignancy: A Real-Life Cohort and Literature Review.","authors":"Ofelia Baniandrés, Inmaculada Balaguer Franch, Eva Vilarrasa Rull, Adrián Imbernón Moya, María Luisa Alonso Pacheco, Almudena Mateu Puchades, Julia Paloma Hergueta Sánchez, Francisco Javier Mataix Díaz, Adrián Ballano Ruiz, Álvaro González Cantero, Elena Martínez Lorenzo, Manuel Galán Gutiérrez, Lourdes Rodríguez Fernández-Freire, Aina Vila Payeras, Carlos Muñoz Santos, Pablo Hernández Bel, Sergio Hernández Ostiz, Josep Pujol Montcusí, Marcial Álvarez Salafranca, Pablo Coto Segura, Isabel Martínez Pallas, Antoni Azón Masoliver, Teresa Martínez Manchón, Carmen Delgado Mucientes, Constantin Luca Schneller-Pavelescu Apetrei, Asunción Ballester Martínez, Juan Monte Serrano, Cristina Pindado Ortega, Leandra Reguero Del Cura, Irene López Barragán, Eva Chavarría Mur, Mónica González Olivares, Pablo de la Cueva Dobao","doi":"10.1111/ijd.70053","DOIUrl":"https://doi.org/10.1111/ijd.70053","url":null,"abstract":"<p><strong>Background: </strong>Tildrakizumab has demonstrated high efficacy and a good long-term safety profile, including low malignancy rates, in Phase III trials with 5-year extension. Despite these data, the real-world evidence on patients with psoriasis and a history of cancer is limited.</p><p><strong>Objectives: </strong>To assess the efficacy and safety of tildrakizumab in a cohort of patients with moderate-to-severe psoriasis and a previous or current history of neoplasia.</p><p><strong>Methods: </strong>We conducted a retrospective, observational, multicentre study across 27 Spanish dermatology departments. All patients had moderate-to-severe plaque psoriasis and a prior history of an active neoplasia at the time of initiating tildrakizumab treatment.</p><p><strong>Results: </strong>Forty-eight patients with a mean follow-up period of 50 weeks after initiation of tildrakizumab were included. At Week 24, 82.4% of evaluable patients achieved a Psoriasis Area and Severity Index (PASI) score < 3. By Week 48, 80.0% achieved PASI < 1 and 50.0% reached PASI 0. Twelve patients (25%) began treatment within one year of cancer diagnosis, and four patients started tildrakizumab prior to cancer detection and did not stop treatment. Of the remaining 32, they started tildrakizumab an average of 4.95 years after the cancer diagnosis. Seven patients had active neoplasia at baseline. Overall, 95.8% of the patients did not experience recurrence or worsening of the neoplasia. No adverse events related to tildrakizumab were reported. The cancer state was not considered affected by the psoriasis therapy in any of the cases.</p><p><strong>Conclusion: </strong>The treatment of moderate to severe psoriasis with tildrakizumab was an effective option, with a safe profile in patients with a history of cancer.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Critical Role of Dermatologists in Screening for Body Dysmorphic Disorder.","authors":"Julian Henke, Sana Kamboj, Travis Blalock, Benjamin Stoff","doi":"10.1111/ijd.70069","DOIUrl":"https://doi.org/10.1111/ijd.70069","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors.","authors":"Mariano Ara-Martín, Carolina Moreno, Ricardo Ruiz-Villaverde, Esther Serra-Baldrich, Irene Hernández-Martín, Maria Del Pilar Fortes","doi":"10.1111/ijd.70033","DOIUrl":"https://doi.org/10.1111/ijd.70033","url":null,"abstract":"<p><p>Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine administration. This document aims to provide dermatologists and other healthcare practitioners with comprehensive practical vaccination recommendations for adults and adolescent patients with atopic dermatitis who are receiving or are about to receive treatment with JAK inhibitors. While inactivated vaccines are safe and recommended during JAK treatment, live attenuated vaccines are contraindicated unless treatment is temporarily discontinued according to clinical guidelines. It is crucial to follow vaccination guidelines established by official agencies and tailor them to individual patient needs. Careful consideration and follow-up are essential to ensure patient safety and optimal therapeutic outcomes.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relapse of IgA Vasculitis With Gastrointestinal Involvement in the Absence of Purpura.","authors":"Kimi Iinuma, Kazuyasu Fujii, Takaya Komori, Shunya Usui, Chisa Nakashima, Atsushi Otsuka","doi":"10.1111/ijd.70066","DOIUrl":"https://doi.org/10.1111/ijd.70066","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Treatment of Refractory Dermatitis Herpetiformis With Upadacitinib.","authors":"Ishana Dixit, Miguel Mansilla-Polo, Jennifer Kim, Pablo Fernández-Peñas","doi":"10.1111/ijd.70067","DOIUrl":"https://doi.org/10.1111/ijd.70067","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nail Involvement as an Early Manifestation of Systemic Light-Chain Amyloidosis.","authors":"Erik J Wanberg, Nadia S El-Hamdi, Julia S Lehman, Nessa Aghazadeh Mohandesi","doi":"10.1111/ijd.70062","DOIUrl":"https://doi.org/10.1111/ijd.70062","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor Mutational Burden, a Proxy for Neoantigen Load, Fails to Correlate With the Abundance of Distinct TIICs in the Cutaneous Melanoma TME.","authors":"Michael J Diaz, Jasmine T Tran, Angela Shar, Jane M Grant-Kels","doi":"10.1111/ijd.70007","DOIUrl":"https://doi.org/10.1111/ijd.70007","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Equitable Sun Protection: Cost-Effectiveness and Cluster Analysis for South Africa.","authors":"Yukun Wen, Shijie Zeng","doi":"10.1111/ijd.70057","DOIUrl":"10.1111/ijd.70057","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rosacea and Migraine: A Systematic Review and Meta-Analysis Update.","authors":"Marina Mordehachvili Burlá, Beatriz Ximenes Mendes, Lucas Mendes Barbosa, Maria Tsoukas, Roger Haber","doi":"10.1111/ijd.70048","DOIUrl":"https://doi.org/10.1111/ijd.70048","url":null,"abstract":"<p><strong>Background: </strong>The association between rosacea and migraine is well-recognized, but the underlying mechanisms remain unclear. Emerging evidence suggests potential benefits of anti-migraine treatments for rosacea, highlighting the need for updated insights. This systematic review and meta-analysis assessed migraine prevalence in rosacea patients, compared it with non-rosacea populations, and explored influencing factors.</p><p><strong>Methods: </strong>Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched databases for observational studies reporting migraine prevalence or odds ratios (ORs) in rosacea patients. Data were analyzed using random-effects models in R 4.4.1. Heterogeneity was assessed via the Cochran Q test, I² statistics, prediction intervals (PI), leave-one-out analyses, meta-regressions, and Baujat plots.</p><p><strong>Results: </strong>From 385 screened studies, 11 met the inclusion criteria, with 112,994 rosacea patients and 4,402,330 non-rosacea participants. The prevalence of migraine in rosacea patients was 25% (95% confidence interval [CI], 0.15; 0.35, p < 0.001, I² = 99%; 95% PI, 0.00; 0.62), indicating substantial variability across populations. Compared to controls, rosacea patients had nearly twice the odds of migraine (OR = 1.93, 95% CI, 1.42; 2.64, p < 0.001, I² = 98%; 95% PI, 0.67; 5.53), though the wide PI suggests that in some populations, the association may not be significant.</p><p><strong>Conclusions: </strong>Qualitative analysis identified erythematotelangiectatic subtype, female gender, age, and severity as potential contributing factors. However, inconsistencies across studies limit definitive conclusions. While we found high migraine prevalence and increased OR in rosacea patients, the substantial heterogeneity underscores the need for further stratification to enhance risk assessment and treatment strategies considering patient and population-level characteristics.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}