International Journal of Dermatology最新文献_第10页

The Efficacy and Safety of 1% Oxyresveratrol for Treating Facial Melasma on Sensitive Skin in Women: A Double-Blind Placebo-Controlled Trial. 1%氧化白藜芦醇治疗女性敏感皮肤面部黄褐斑的疗效和安全性：一项双盲安慰剂对照试验。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1111/ijd.17882

Jianhua Zhang, Shichao Liu, Wenjiao Guo, Yun Huang, Na Li

引用次数: 0

Eosinophilic Fasciitis: New Developments and Future Directions 嗜酸性筋膜炎：新的发展和未来的方向。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1111/ijd.17809

Michelle Huynh, Emily Bogdanski, Taylor Fleshman, Justine Schneider, Karissa Libson, Victoria P. Werth, Judith Lin, Abraham M. Korman

{"title":"Eosinophilic Fasciitis: New Developments and Future Directions","authors":"Michelle Huynh, Emily Bogdanski, Taylor Fleshman, Justine Schneider, Karissa Libson, Victoria P. Werth, Judith Lin, Abraham M. Korman","doi":"10.1111/ijd.17809","DOIUrl":"10.1111/ijd.17809","url":null,"abstract":"<div>\u0000 \u0000 <p>Eosinophilic fasciitis (EF), also known as Shulman's disease, is a rare, autoimmune sclerosing connective tissue disorder. The purpose of this review is to provide clinicians with a comprehensive summary of the latest information on the diagnosis and management of EF. The pathogenesis of EF is unclear; however, it is believed to involve increased fibroblast activity and interleukins linked to eosinophilia, such as interleukin (IL)-5. While mostly idiopathic, triggers include exercise, trauma, infection, and specific medications. The disease is typically characterized by erythema, edema, and induration of extremities, with laboratory findings including peripheral eosinophilia and hypergammaglobulinemia. EF is typically mistaken for other sclerosing diseases, such as systemic sclerosis and morphea. Diagnostic workup for EF may include an initial complete blood count (CBC) with differential, followed by erythrocyte sedimentation rate and aldolase to classify severity, and a systemic hematologic workup if indicated. A full-thickness skin-to-muscle (including fascia) incisional biopsy is the diagnostic gold standard though magnetic resonance imaging (MRI) may be highly sufficient. Ultrasound presents as an accessible tool for determining the biopsy site and supporting a diagnosis of EF. While commonly treated with corticosteroids and methotrexate, studies have revealed that many patients are refractory to these traditional therapies. Biologic therapies have shown utility in treatment-resistant EF, often resulting in at least partial resolution of their disease. The long-term prognosis for EF is reliant on treatment and its timelines. Complications, such as decreased range of motion, can significantly impact patients' quality of life. Further research should focus on understanding EF pathogenesis, diagnostic strategies for early detection, and assessing newer therapies in prospective clinical trials.</p>\u0000 </div>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"64 8","pages":"1356-1370"},"PeriodicalIF":3.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Old Doubts From a New Perspective: Oral Versus Subcutaneous Methotrexate. 从新的角度看旧的疑虑：口服甲氨蝶呤与皮下甲氨蝶呤。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1111/ijd.17879

Laura Kiss, Rolland Gyulai

引用次数: 0

Disseminated Toxoplasmosis Presenting With Panniculitis in a Renal Transplant Recipient. 肾移植受者播散性弓形虫病伴泛膜炎。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1111/ijd.17881

Sylvia Huang, Jeva Cernova, Diana Mabayoje, Gauri Godbole, Marcin Ligaj, Catherine Harwood

引用次数: 0

Bilateral Asymptomatic Erythematous Plaques on Soles in an Adult Woman 1例成年女性双侧足底无症状红斑斑块。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1111/ijd.17883

Mariana El Hawa, Dana M. Khoury, Nelly Rubeiz, Abdul Ghani Kibbi, Ossama Abbas

引用次数: 0

Multiple Bullae and Indurated Ulcers in a Middle-Aged Woman. 一名中年妇女多发性大疱和硬化性溃疡。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1111/ijd.17884

Ananya Sharma, Shipra Agarwal, Neha Taneja

引用次数: 0

The Rise of Sexually Acquired Trichophyton mentagrophytes Genotype VII Infections. 性获得性毛癣菌基因型VII感染的增加。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1111/ijd.17876

Hitaishi Mehta, Anuradha Bishnoi, Shivaprakash M Rudramurthy, Sunil Dogra

引用次数: 0

Optimization of Basic Emollient Therapy for the Management of Xerosis Cutis 皮肤干燥症基本润肤疗法的优化

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-05-30 DOI: 10.1111/ijd.17791

Matthias Augustin, Mélanie Brignone

{"title":"Optimization of Basic Emollient Therapy for the Management of Xerosis Cutis","authors":"Matthias Augustin, Mélanie Brignone","doi":"10.1111/ijd.17791","DOIUrl":"https://doi.org/10.1111/ijd.17791","url":null,"abstract":"<p>Topical emollients are the mainstay of basic therapy for managing xerosis cutis (dry skin). In general, most emollient formulations are safe and effective for xerosis cutis and diseases associated with dry skin; however, several other factors can vary widely between products, influence patient adherence, and ultimately affect treatment success. This article reviews key practical and clinical considerations when prescribing emollients for xerosis cutis and discusses strategies to optimize treatment and clinical outcomes for these patients. Although the optimal quantity and frequency of emollient use depend on the extent and severity of skin dryness, frequent (i.e., up to several times daily) and liberal application (i.e., up to 600 g/week) are generally recommended. Lipid-rich ointments are indicated for very dry skin, while hydrophilic creams and lotions are suitable for less severe xerosis cutis; however, treatment decisions should also be guided by other factors (e.g., cosmetic acceptability and practicality) to ensure that patients can adhere to long-term emollient therapy. Strategies to promote shared decision-making and improve treatment adherence include patient education, allowing patients to trial a range of emollient products, regularly following-up with patients, and adjusting treatment to suit their preferences. Emollient therapy is a cost-effective strategy to manage patients with chronic dry skin conditions; however, access to basic, lower-cost formulations remains important to minimize the financial burden on patients. Overall, treatment effectiveness and clinical need should be balanced with individual patient preferences to ensure that the full benefits of emollient therapy for xerosis cutis are realized.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"64 S1","pages":"53-57"},"PeriodicalIF":3.5,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijd.17791","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Basic Emollients for Xerosis Cutis Not Associated With Atopic Dermatitis: A Review of Clinical Studies 与特应性皮炎无关的干燥性皮肤的基础润肤剂：临床研究综述

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-05-30 DOI: 10.1111/ijd.17794

Jacek C. Szepietowski, Gianluca Tadini

{"title":"Basic Emollients for Xerosis Cutis Not Associated With Atopic Dermatitis: A Review of Clinical Studies","authors":"Jacek C. Szepietowski, Gianluca Tadini","doi":"10.1111/ijd.17794","DOIUrl":"https://doi.org/10.1111/ijd.17794","url":null,"abstract":"<div>\u0000 \u0000 <p>Xerosis cutis (dry skin) is a common dermatological condition that occurs when the water-holding or barrier functions of the skin are impaired. In addition to external triggers, xerosis cutis may be caused by endogenous factors (e.g., aging) or present as a symptom of other diseases, such as atopic dermatitis, psoriasis, ichthyosis, and diabetes. Basic emollients restore skin hydration and barrier function through the biophysical properties of their non-active constituents and are routinely recommended for treating xerosis cutis and diseases associated with dry skin. As newer “emollients plus” containing active ingredients become available, we believe there is still a place for basic emollients as safe and cost-effective treatment options for the long-term management of dry skin. The previous article in this supplement reviewed basic emollients for the treatment of xerosis cutis in atopic dermatitis; herein, we review evidence describing the clinical value of basic emollients for dry skin associated with other causes. Twenty-one literature searches were performed to identify clinical studies of basic emollients containing one or more of the following ingredients: almond and coconut oils, amino acids, chondroitin, dexpanthenol, glucose, glycerol, glycosaminoglycans, hyaluronic acid, lactic acid, lanolin, olive oil, paraffin, petrolatum, phospholipids, polyunsaturated fatty acids, pyroglutamic acid, squalene, triglycerides, urea, vegetable oils, and vitamin E. Despite wide variations in study design and outcome measures, articles of interest identified by the authors show that most basic emollient formulations are safe and effective at improving dry skin associated with senile xerosis, uremic xerosis, psoriasis, ichthyosis, and diabetes. Overall, current clinical evidence reaffirms that regular and ongoing emollient use should be the mainstay of basic therapy for xerosis cutis and diseases associated with dry skin.</p>\u0000 </div>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"64 S1","pages":"29-46"},"PeriodicalIF":3.5,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Necrobiotic Xanthogranuloma With Upadacitinib: A Case Report. Upadacitinib治疗坏死性黄色肉芽肿1例。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2025-05-30 DOI: 10.1111/ijd.17873

Austinn C Miller, Tanner Harding, Jessica Houpe, Emily Jacox, András Schaffer, Amit Jain, Michael Bernhardt

引用次数: 0