International Journal of Dermatology最新文献

{"title":"Enhancing Healing in Hidradenitis Suppurativa With Tobacco Pouch Suture After CO2 Laser Excision Treatment","authors":"Martina Mussi, Michelangelo La Placa, Valeria Gaspari, Antonio Russo, Davide Melandri, Bianca Maria Piraccini, Corrado Zengarini","doi":"10.1111/ijd.17679","DOIUrl":"10.1111/ijd.17679","url":null,"abstract":"<p>While medical therapies are the mainstay for early stages, treating advanced hidradenitis suppurativa (HS) poses challenges due to the frequent recurrence of lesions, which often requires wider surgical excisions [<span>1</span>]. This can lead to delayed wound healing, an increased risk of complications and scarring, and significant patient discomfort, creating a notable barrier to surgical management [<span>2</span>]. Carbon dioxide (CO<sub>2</sub>) laser treatment has proven to be an effective modality for reducing recurrence and improving outcomes compared to traditional surgery [<span>3</span>]. However, further refinements in this technique are still needed to enhance its overall effectiveness, as well as wound management after surgical intervention [<span>4</span>].</p><p>We propose to use a tobacco pouch suture following CO<sub>2</sub> laser debulking to enhance wound margin approximation and accelerate healing. This technique involves placing a continuous purse-string suture around the wound's circumference, drawing the edges inward, reducing the wound area, and minimizing tension, which lowers the risk of dehiscence (Figure 1). In our experience, this method led to faster granulation and full re-epithelialization compared to other treatments that did not incorporate this specific suture technique, resulting in minimal scarring and significantly reducing patient discomfort and pain during recovery.</p><p>As a representative case, we present a 35-year-old male suffering from HS since the age of 12, who progressed to Hurley Stage III, International Hidradenitis Suppurativa Severity (IHS4)-score 13 [<span>5</span>], with HS of the left axilla with refractory lesions unresponsive to antibiotics, biologics, and topical therapies. Treatment with adalimumab was discontinued after 13 months of administration for the development of anti-TNF-alpha antibodies. Given the lack of response to medical therapies, ablative surgical management was pursued, and CO<sub>2</sub> laser excision was performed under local anesthesia after 2 months of adalimumab suspension. Guerbet blue patent V staining was previously injected into the sinus tracts to delineate their course and depth accurately, guiding the excision of diseased tissue (Figure 1a,b). Both continuous and SmartPulse modes of the DEKA CO<sub>2</sub> laser were utilized, with power settings ranging from 2 to 5 watts for the continuous mode and 30 to 45 W for the SmartPulse mode. Following laser debulking, the wide surgical defect created significant wound tension.</p><p>To address this, we employed a tobacco pouch suture technique, a continuous purse-string suture around the wound's circumference, with 3-0 prolene, which reduced tension and promoted wound edge approximation (Figure 1b,c). A collagen-based dressing was applied, followed by sterile gauze and bandage. Postoperatively, the patient was medicated every 48 hours with betadine-based antiseptic gauzes and bandages and received only on-dema","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"64 5","pages":"909-910"},"PeriodicalIF":3.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijd.17679","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reframing Filler-Induced Alopecia: Recognizing Pressure Alopecia as a Distinct Mechanism in Injectable Complications.","authors":"Eduardo Corona-Rodarte, Luis Enrique Cano-Aguilar, Jonathan Matias Chejfec-Ciociano, Antonella Tosti, Daniel Asz-Sigall","doi":"10.1111/ijd.17662","DOIUrl":"https://doi.org/10.1111/ijd.17662","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor's Highlights—March 2025","authors":"Lajos Kemény","doi":"10.1111/ijd.17676","DOIUrl":"10.1111/ijd.17676","url":null,"abstract":"<div>\u0000 \u0000 <p>Managing chronic inflammatory skin diseases such as hidradenitis suppurativa (HS) and psoriasis extends beyond clinical measures; it should also consider patient-reported outcomes, treatment burden, and overall satisfaction. Successful therapy in both conditions is influenced by factors such as residual disease activity, the psychological profiles of patients, and the availability of new treatment options. The coexistence of psoriasis and atopic dermatitis can pose significant diagnostic and therapeutic challenges. In such rare cases, Janus kinase inhibitors may be considered a treatment option instead of biologics.</p>\u0000 </div>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"64 3","pages":"459-460"},"PeriodicalIF":3.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eruptive dysplastic melanocytic nevi induced by setmelanotide.","authors":"Lily Kaufman, Andrew Krispinsky, Catherine G Chung, Abraham M Korman","doi":"10.1111/ijd.17644","DOIUrl":"https://doi.org/10.1111/ijd.17644","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hidradenitis Suppurativa Treatment During Pregnancy and Lactation: Navigating Challenges.","authors":"Laşin Özbek, Mustafa Güldan, Erkan Alpsoy, Seçil Vural","doi":"10.1111/ijd.17672","DOIUrl":"https://doi.org/10.1111/ijd.17672","url":null,"abstract":"<p><p>Hidradenitis suppurativa (HS), or acne inversa, is a chronic inflammatory skin condition primarily affecting skin folds such as the axilla, groins, and the inframammary, perineal, and perianal regions. It is characterized by painful abscesses, sinus tracts, and scarring. Predominantly affecting young adults, particularly females, HS often emerges during reproductive age, and flares are widely reported during pregnancy and postpartum, underscoring the need to consider management strategies tailored to pregnant or lactating individuals. Moreover, the chronic and relapsing nature of HS, along with challenges related to the safety and compliance of medication use during pregnancy and lactation, as well as various comorbidities and psychological distress, significantly complicate its management in pregnant or lactating women. Treatment options, including topical clindamycin, oral clindamycin-rifampicin, adalimumab, metformin, antiseptic washes, and certolizumab pegol, have accumulated evidence supporting their relative safety in pregnant and lactating women. While certolizumab pegol has shown promising safety data among biologics, it requires more efficacy data in HS. Conversely, while newly approved HS medications such as secukinumab and bimekizumab show promise for the general population, further research is necessary to evaluate their safety profiles in pregnant and breastfeeding individuals. The scant research available on HS in pregnant and lactating women, also shown by our systematic literature review, highlights the need for a comprehensive investigation into the safety, efficacy, and suitability of management strategies.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psoriasis in People With Skin of Color: An Evidence-Based Update","authors":"Maria-Angeliki Gkini,&nbsp;Mio Nakamura,&nbsp;Andrew F. Alexis,&nbsp;Angela Londoño-Garcia,&nbsp;Peter C. M. van de Kerkhof,&nbsp;Nejib Doss,&nbsp;Christopher E. M. Griffiths,&nbsp;Bridget Kaufman,&nbsp;Christine E. Kleyn,&nbsp;Mark Lebwohl,&nbsp;Jan S. Redfern,&nbsp;Junko Takeshita,&nbsp;Murlidhar Rajagopalan,&nbsp;Mahira H. El Sayed","doi":"10.1111/ijd.17651","DOIUrl":"10.1111/ijd.17651","url":null,"abstract":"<p>Variations in epidemiology, pathophysiology, genetics, clinical presentation, management, quality of life (QoL) impact, and access to care and research exist globally across the spectrum of individuals with psoriasis. This article aims to provide an evidence-based update on the characteristics of psoriasis in individuals with skin of color (SOC), a population in which psoriasis data have historically been limited. A literature search was conducted from January 2018 until August 2023 in Pubmed/MEDLINE/Cochrane Library and identified studies with I-III level of evidence using Oxford Centre for Evidence-Based Medicine recommendations. Multiple factors (including biological and non-biological) contribute to differences in clinical features and therapeutic nuances in patient populations with SOC. The prevalence of plaque psoriasis is lower in people with SOC but tends to be more severe. People with SOC are less likely to receive biologic treatment. Although the QoL impact of psoriasis is worse in populations with SOC than in White populations, more research is needed to elucidate variations in presentation and impact across diverse populations. An important limitation of this study is that ethnicity, race, and SOC have not been defined universally or used consistently in the literature. Available evidence provides limited information on populations with SOC outside North America, which limits generalizability across global populations. Furthering our understanding of psoriasis in individuals with SOC is crucial to improving patient care outcomes for diverse patient populations worldwide.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"64 4","pages":"667-677"},"PeriodicalIF":3.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijd.17651","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality-of-Life Measurement in Epidermolysis Bullosa. Position Statement of the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient-Oriented Outcomes and External Experts.","authors":"Pavel V Chernyshov, Andrew Y Finlay, Lucia Tomas-Aragones, Francoise Poot, Dedee F Murrell, Nives Pustisek, Ake Svensson, Servando E Marron, Francesca Sampogna, Anthony Bewley, Carmen Salavastru, Dimitra Koumaki, Alina Suru, Ivelina A Yordanova, Serhiy Zemskov, Ruslan Tsymbaliuk, Olena Ostapko, Matthias Augustin, Damiano Abeni, Jacek C Szepietowski, Gregor B Jemec","doi":"10.1111/ijd.17668","DOIUrl":"https://doi.org/10.1111/ijd.17668","url":null,"abstract":"<p><p>In this paper, the European Academy of Dermatology and Venereology (EADV) Task Force on Quality of Life (QoL) and Patient-Oriented Outcomes presents its position statements on health-related (HR) QoL assessment in epidermolysis bullosa (EB). The EADV TF on QoL and Patient-Oriented Outcomes recommends the use of the EB-specific instrument QOLEB in patients over the age of 10 years and, in addition to the QOLEB, the use of iscorEB-p in moderate-to-severe EB; the IntoDermQoL proxy instrument with its EB-specific module should be used in children aged under 5 years. The EB-specific instrument iscorEB-p, and the dermatology-specific instrument CDLQI may measure HRQoL in children with EB aged from 5 to 10 years. Dermatology-specific and/or generic HRQoL instruments should be used to compare the impact on QoL of EB with other diseases; family QoL of patients with EB should be studied using the EB-specific EB-BoD, dermatology-specific family measures, and/or generic family QoL instruments.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing the Understanding and Management of Segmental Vitiligo and Co-Existing Pigmentary Disorders","authors":"Rashmi Sarkar,&nbsp;Keshavamurthy Vinay","doi":"10.1111/ijd.17667","DOIUrl":"10.1111/ijd.17667","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"64 3","pages":"461-462"},"PeriodicalIF":3.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilizing AI to Improve Healthcare Access and Address Disparities in Dermatology.","authors":"Mehmet Fatih Atak, June Y Moon, Bijan Safai, Banu Farabi","doi":"10.1111/ijd.17670","DOIUrl":"https://doi.org/10.1111/ijd.17670","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatologic Needs for People Experiencing Homelessness Evaluated in a Free Clinic","authors":"Kathryn K. Xu,&nbsp;Anne L. King,&nbsp;Deborah B. Cull,&nbsp;Keegan O'Hern,&nbsp;Beth Kangas,&nbsp;Carilyn N. Wieland","doi":"10.1111/ijd.17671","DOIUrl":"10.1111/ijd.17671","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":"64 5","pages":"911-914"},"PeriodicalIF":3.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}