International Journal of Dermatology最新文献_第10页

Severity and Therapeutic Decisions Based on Lesion Location in Patients With Hidradenitis Suppurativa. 基于病灶部位的化脓性汗腺炎的严重程度和治疗决策。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-05-20 DOI: 10.1111/ijd.17861

Daniel Muñoz-Barba, Sofía Haselgruber de Francisco, Francisco Javier León-Pérez, Carlos Cuenca-Barrales, Salvador Arias-Santiago, Manuel Sánchez-Díaz, Alejandro Molina-Leyva

{"title":"Severity and Therapeutic Decisions Based on Lesion Location in Patients With Hidradenitis Suppurativa.","authors":"Daniel Muñoz-Barba, Sofía Haselgruber de Francisco, Francisco Javier León-Pérez, Carlos Cuenca-Barrales, Salvador Arias-Santiago, Manuel Sánchez-Díaz, Alejandro Molina-Leyva","doi":"10.1111/ijd.17861","DOIUrl":"10.1111/ijd.17861","url":null,"abstract":"Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease for which several phenotypic classifications have been proposed in recent years to optimize medical care. The aim of this study was to define a new classification of HS based on the anatomical distribution of lesions, serving as a tool for therapeutic decision-making.Methods: This cross-sectional study with consecutive sampling included patients attending their first medical consultation at the Hidradenitis Suppurativa Unit of Virgen de las Nieves University Hospital in Granada, Spain, between January 1, 2017, and March 1, 2024. Patients were classified into four groups based on the anatomical distribution of HS: Upper, Atypical, Lower, and Progressor HS. Sociodemographic variables, personal history, and HS-related variables were collected.Results: A total of 557 patients were included, with a similar proportion of men and women. Patients with the Upper type exhibited milder forms of HS and underwent surgical treatment more frequently. In contrast, those with the Progressor type presented more severe forms of HS and required more immunomodulatory treatment. Patients in the Atypical and Lower groups showed more heterogeneity in therapeutic approaches, although the presence of lesions in specific locations may help predict the need for early initiation of more aggressive treatments.Conclusions: We propose a new HS classification based on the location of lesions. This classification can be used alone or in conjunction with previous ones to identify patients at higher risk of progression and to guide therapeutic decision-making.","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":"1607-1614"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology of Psoriasis in Poland: Prevalence, Incidence, and Mortality Rates. 波兰牛皮癣的流行病学：患病率、发病率和死亡率。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-05-19 DOI: 10.1111/ijd.17848

Joanna Bartosińska, Jacek C Szepietowski, Dorota Raczkiewicz, Christopher E M Griffiths, Darren M Ashcroft, Alison K Wright, Krzysztof Podwójcic, Jakub Turcza, Michał Maluchnik, Agnieszka Chłoń-Domińczak, Dorota Krasowska

{"title":"Epidemiology of Psoriasis in Poland: Prevalence, Incidence, and Mortality Rates.","authors":"Joanna Bartosińska, Jacek C Szepietowski, Dorota Raczkiewicz, Christopher E M Griffiths, Darren M Ashcroft, Alison K Wright, Krzysztof Podwójcic, Jakub Turcza, Michał Maluchnik, Agnieszka Chłoń-Domińczak, Dorota Krasowska","doi":"10.1111/ijd.17848","DOIUrl":"10.1111/ijd.17848","url":null,"abstract":"Background: Although the data on psoriasis epidemiology included in the Global Psoriasis Atlas (GPA) provide valuable information on psoriasis prevalence worldwide, the GPA database is still incomplete. Therefore, the aim of the study was to assess the prevalence, incidence, and mortality rates of psoriasis and its types in Poland based on the data registered by the National Health Fund (NHF).Methods: The study included psoriasis patients registered at least twice in the Polish NHF database between 2010 and 2023.Results: At the end of 2023, 639,662 living psoriasis patients had been registered in the Polish NHF database, which constituted 1.70% of the Polish general population. The percentage of female psoriasis patients was found to be higher (54.95%) than male patients (45.05%). Of all the Polish NHF-registered psoriasis patients, plaque psoriasis affected 95.66%, pustular psoriasis 3.05%, psoriatic arthritis 7.20%, and guttate psoriasis 0.27%. In comparison to the general Polish population, psoriasis prevalence was observed to be lower in children (0.84%). The all-cause mortality rate among psoriasis patients was found to be higher in comparison to the general Polish population, with a higher mortality rate noted in male psoriasis patients.Conclusions: The NHF database we studied suggests a direct relationship between the prevalence, incidence, and all-cause mortality rates in psoriasis and patients' age and sex. However, the study also revealed a decrease in mortality rates and a slow increase in the prevalence of psoriasis in the Polish population, which calls for further studies.","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":"1599-1606"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12332235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Old Doubts From a New Perspective: Oral Versus Subcutaneous Methotrexate. 从新的角度看旧的疑虑：口服甲氨蝶呤与皮下甲氨蝶呤。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-06-01 DOI: 10.1111/ijd.17879

Laura Kiss, Rolland Gyulai

引用次数: 0

Comprehensive Literature Review Evaluating the Use, Safety, and Efficacy of Subcutaneous Methotrexate in the Treatment of Adult Patients With Moderate-To-Severe Plaque-Type Psoriasis. 综合文献综述：评价甲氨蝶呤皮下注射治疗成人中重度斑块型银屑病的使用、安全性和有效性。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-04-01 DOI: 10.1111/ijd.17758

Manuelle Viguier, José-Manuel Carrascosa-Carrillo, Pariyawan Rakvit, Maria-Magdalena Constantin, Alice-Anaïs Varlet, Solenn Le Clanche, Linda A W Verhagen, Wolf-Henning Boehncke

{"title":"Comprehensive Literature Review Evaluating the Use, Safety, and Efficacy of Subcutaneous Methotrexate in the Treatment of Adult Patients With Moderate-To-Severe Plaque-Type Psoriasis.","authors":"Manuelle Viguier, José-Manuel Carrascosa-Carrillo, Pariyawan Rakvit, Maria-Magdalena Constantin, Alice-Anaïs Varlet, Solenn Le Clanche, Linda A W Verhagen, Wolf-Henning Boehncke","doi":"10.1111/ijd.17758","DOIUrl":"10.1111/ijd.17758","url":null,"abstract":"Methotrexate (MTX) is a conventional systemic therapy widely used to treat chronic plaque-type psoriasis, a chronic inflammatory skin disease that significantly impacts patients' quality of life. MTX can be administered orally or subcutaneously. Over the past decades, the use of subcutaneous versus oral MTX has been a subject of ongoing debate among dermatologists. Therefore, this literature review aimed to investigate the differences between oral and subcutaneous MTX described in the scientific literature in terms of intestinal absorption and bioavailability, efficacy, safety, patient satisfaction and quality of life, treatment adherence, and economic outlook. Thirty-two articles were included in the review, notably including evidence-based guidelines on the management of psoriasis, as well as randomized clinical trials and real-world studies. Only European guidelines recommend the use of subcutaneous MTX over oral MTX; hence, the use of subcutaneous MTX is reported almost exclusively in European countries. Despite the paucity and heterogeneity of the literature, findings from the review suggest that subcutaneous MTX may overcome some limitations of the oral route in terms of intestinal absorption, bioavailability, and safety. Moreover, subcutaneous MTX may provide higher efficacy with a faster, or even greater, response in psoriatic patients and better adherence to treatment. In conclusion, subcutaneous MTX tends to be advantageous with regard to psoriasis management, similar to other chronic inflammatory diseases like rheumatoid arthritis; however, this comes with a higher cost. The treatment of psoriasis using subcutaneous MTX deserves further study, especially in the biologics age.","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":"1558-1567"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12332243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biallelic postzygotic RASA1 variants in a germline-negative patient with capillary malformation-arteriovenous malformation. 种系阴性毛细血管畸形-动静脉畸形患者的双等位基因合子后RASA1变异。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-01-03 DOI: 10.1111/ijd.17642

Céline Granier Tournier, Maella Severino-Freire, Juliette Mazereeuw-Hautier, Charlene Denos, Juliette Piard, Pierre Vabres, Paul Kuentz

引用次数: 0

Effect of Dupilumab Therapy on Patch Test Results for Atopic Contact Dermatitis: A Systematic Review. 杜匹单抗治疗对特应性接触性皮炎斑贴试验结果的影响：一项系统综述。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 DOI: 10.1111/ijd.70041

Dennis Chu, Katelyn Tao, William Guo, James Briley

引用次数: 0

The Association of Acne Vulgaris With Anxiety And Depression by Race: A Case-Control Study in the All of Us Research Program. 寻常痤疮与种族焦虑和抑郁的关系：我们所有人研究项目的病例对照研究。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-02-23 DOI: 10.1111/ijd.17693

Sara D Ragi, Megan Hoang, Amar D Desai, Zachary Lin, Neelam A Vashi

引用次数: 0

Epidermolysis Bullosa and Psychodermatology. 大疱性表皮松解症与皮肤精神病学。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-04-30 DOI: 10.1111/ijd.17811

Csanád Szabó

引用次数: 0

Clinical Outcomes and Prognosis in Atypical Fibroxanthoma: A Systematic Review and Meta-Analysis. 非典型纤维黄色瘤的临床结果和预后：一项系统综述和荟萃分析。

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-05-11 DOI: 10.1111/ijd.17841

Rebecca von Dannecker, Lilia Maria Lima de Oliveira, Izadora Lapenda, Luiza Pinto, Sarah Soares Amorim, Eduarda Pandia, Michele Kreuz, Ana Julia Marques Bluhm, Matheus de Melo Lobo

{"title":"Clinical Outcomes and Prognosis in Atypical Fibroxanthoma: A Systematic Review and Meta-Analysis.","authors":"Rebecca von Dannecker, Lilia Maria Lima de Oliveira, Izadora Lapenda, Luiza Pinto, Sarah Soares Amorim, Eduarda Pandia, Michele Kreuz, Ana Julia Marques Bluhm, Matheus de Melo Lobo","doi":"10.1111/ijd.17841","DOIUrl":"10.1111/ijd.17841","url":null,"abstract":"Atypical fibroxanthoma (AFX) is a rare dermal spindle-cell tumor characterized by a generally benign clinical course. Despite recent advances, there are still challenges regarding its accurate diagnosis, prognostic indicators, and optimal management strategies. This systematic review and meta-analysis aims to evaluate recurrence rates, identify prognostic factors, and provide evidence-based insights for managing AFX. We systematically searched the PubMed, Embase, Web of Science, and Cochrane databases following PRISMA guidelines (PROSPERO: CRD42024507089). Observational studies published from 2002 to 2024 that confirmed AFX through histopathology and immunohistochemistry were included. Recurrence rates and prognostic factors were analyzed using a random-effects model with inverse-variance weighting. Sensitivity analysis assessed heterogeneity, while publication bias was evaluated via funnel plots and Egger's test. Eight studies involving 1366 patients were analyzed. Patients were predominantly elderly males (78.9%), with an average age of 76.9 years, and lesions mostly in the head and neck region (89%), measuring about 14.9 mm in diameter. The pooled local recurrence rate was 4.73% [95% confidence interval (CI): 2.24-9.73%; I2 = 62.1%], while the metastasis rate was 0.59%, and disease-specific mortality was 0%. Strict adherence to standardized diagnostic criteria results in low recurrence rates in AFX, reinforcing its predominantly benign clinical behavior. Therefore, we highlight the importance of maintaining strict diagnostic standards for AFX to ensure accurate patient prognosis.","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":"1592-1598"},"PeriodicalIF":3.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 3.2 4区医学

International Journal of Dermatology Pub Date : 2025-09-01 Epub Date: 2025-04-16 DOI: 10.1111/ijd.17778

Ioanna A Paschou, Vasiliki I Drantaki, Maria Gerochristou, Irene Stefanaki, Antonina Lingria, Alexander J Stratigos, Vasiliki Nikolaou

引用次数: 0