International Journal of Dermatology最新文献_第10页

A look back on 2024

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-12-09 DOI: 10.1111/ijd.17605

Lajos Kemény

引用次数: 0

Advances of the exposome at individual levels and prevention in atopic dermatitis. 特应性皮炎个体暴露与预防研究进展。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-12-04 DOI: 10.1111/ijd.17559

Mo Xian, Anish R Maskey, Daniel Kopulos, Xiu-Min Li

{"title":"Advances of the exposome at individual levels and prevention in atopic dermatitis.","authors":"Mo Xian, Anish R Maskey, Daniel Kopulos, Xiu-Min Li","doi":"10.1111/ijd.17559","DOIUrl":"https://doi.org/10.1111/ijd.17559","url":null,"abstract":"Atopic dermatitis (AD), or eczema, is an inflammatory skin disease related to environmental factors. As a heterogeneous disease, it presents with complex phenotypes and endotypes. A variety of intrinsic and extrinsic factors can promote the development of AD. While there has been extensive discussion on environmental exposure at the population and community levels, discourse on exposome at individual levels in AD remains insufficient. For example, allergens, microorganisms, parasites, dietary factors, and psychological factors such as stress and anxiety play important roles in AD development. Microorganisms, in particular, exhibit altered composition and diversity on the skin of AD patients, influencing skin barrier integrity and immune responses. The impact of certain microorganisms, such as fungi and viruses, on AD has garnered increasing attention because of their important role in maintaining skin homeostasis. Dietary factors, including sugar intake and histamine-rich foods, may modulate AD risk and severity, although findings are controversial. Allergens, particularly house dust mite allergens, and aeroallergens, exacerbate AD symptoms by promoting inflammation and barrier dysfunction. Since AD is often the first step in the atopic march, its primary prevention measures are crucial. Some preventive measures involving microorganisms, diet, and moisturizers remain controversial. Effective preventive strategies necessitate a clear understanding of the complex mechanisms of AD, especially host-microbe-environment interactions. This review summarizes recent advances in understanding various risk and protective factors, as well as primary prevention measures for AD.","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to: Upadacitinib for the management of overlapping psoriasis and atopic dermatitis: a case series 回复：Upadacitinib用于治疗重叠性牛皮癣和特应性皮炎：一个病例系列。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-12-04 DOI: 10.1111/ijd.17594

Luciano Foggia, Luca Potestio, Cataldo Patruno, Francesca di Vico, Maddalena Napolitano

引用次数: 0

Non-syndromic multiple pigmented basal cell carcinomas presenting in an immunocompetent Bangladeshi individual. 非综合征性多发性色素基底细胞癌呈现在免疫正常的孟加拉个体。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-12-04 DOI: 10.1111/ijd.17585

Onjona B Hossain, David H Ciocon, Ramone F Williams

引用次数: 0

Surgical treatment of pilomatrix carcinoma: a systematic review. 毛基质癌的外科治疗：系统回顾。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-12-04 DOI: 10.1111/ijd.17596

Hannah R Riva, Nehaa Sohail, Mojahed Mohammad K Shalabi, Benjamin Kelley, Cary Chisholm, Stanislav N Tolkachjov

{"title":"Surgical treatment of pilomatrix carcinoma: a systematic review.","authors":"Hannah R Riva, Nehaa Sohail, Mojahed Mohammad K Shalabi, Benjamin Kelley, Cary Chisholm, Stanislav N Tolkachjov","doi":"10.1111/ijd.17596","DOIUrl":"https://doi.org/10.1111/ijd.17596","url":null,"abstract":"Pilomatrix carcinoma (PMC), also known as pilomatrical carcinoma, is a rare, malignant tumor of the hair follicle that may arise from a benign pilomatricoma or de novo and carries a high risk of recurrence and metastasis. This study sought to investigate and compare surgical modalities for PMC, including reported outcomes and recurrence rates. In July 2024, a systematic review of PubMed, Embase, and Web of Science databases on surgical modalities and PMC was conducted. Randomized controlled trials and observational studies were included. The search yielded 257 articles; after the application of inclusion and exclusion criteria, 50 articles were included: four case series and 46 case reports with a total of 101 cases. There were 17 cases treated with Mohs micrographic surgery (MMS) with no recurrences. There were 84 cases treated with surgical excision with an overall recurrence rate of 34.5%. The mean follow-up time was 7.5 months for MMS and 7.6 months for surgical excision. MMS showed excellent outcomes for PMC with no recurrences compared with a recurrence rate of 34.5% for surgical excision (P < 0.0025). No recurrences or metastases were found on follow-up reported in all 17 cases treated with MMS in the literature, compared with a recurrence rate of 34.5% for the 84 cases of surgical excision. Due to the importance of early surgical intervention and attaining true negative margins to prevent recurrence and metastasis, MMS should be considered for the treatment of PMC, especially where tissue sparing is essential.","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of basal cell carcinoma by machine learning-assisted ex vivo confocal laser scanning microscopy. 机器学习辅助离体共聚焦激光扫描显微镜检测基底细胞癌。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-12-03 DOI: 10.1111/ijd.17519

Pinar Avci, Marie C Düsedau, Víctor Padrón-Laso, Zan Jonke, Ramona Fenderle, Florian Neumeier, Ikenna U Ikeliani

{"title":"Detection of basal cell carcinoma by machine learning-assisted ex vivo confocal laser scanning microscopy.","authors":"Pinar Avci, Marie C Düsedau, Víctor Padrón-Laso, Zan Jonke, Ramona Fenderle, Florian Neumeier, Ikenna U Ikeliani","doi":"10.1111/ijd.17519","DOIUrl":"https://doi.org/10.1111/ijd.17519","url":null,"abstract":"Background: Ex vivo confocal laser scanning microscopy (EVCM) is an emerging imaging modality that enables near real-time histology of whole tissue samples. However, the adoption of EVCM into clinical routine is partly limited because the recognition of modality-specific diagnostic features requires specialized training. Therefore, we aimed to build a machine learning algorithm for the detection of basal cell carcinoma (BCC) in images acquired using EVCM and, in turn, facilitate the examiner's decision-making process.Methods: In this proof-of-concept study, histologically confirmed BCC fresh tissue samples were used to generate 50 EVCM images to train and assess a convolutional neural network architecture (MobileNet-V1) via tenfold cross-validation.Results: Overall sensitivity and specificity of the model for detecting BCC and tumor-free regions on EVCM images compared to expert evaluation were 0.88 and 0.85, respectively. We constructed receiver operator characteristic and precision-recall curves from the aggregated tenfold cross-validation to assess the model's performance; the area under the curve was 0.94 and 0.87, respectively. Subsequently, the performance of one of the selected machine learning models was assessed with 19 new EVCM images of tumor-containing (n = 10) and 9 tumor-free (n = 9) skin tissue. A sensitivity of 0.83 and a specificity of 0.92 were achieved for the BCC group. The specificity for the tumor-free control group was 0.98.Conclusion: The deep learning model developed in our study holds the potential to assist the diagnostic decision-making process and diminish the training time of novices by depicting tumor-positive regions in EVCM images.","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occupational chemical exposure: A case of patterned squamous cell carcinoma in a radiology technician. 职业性化学暴露：放射科技术人员一例片状鳞状细胞癌。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-11-29 DOI: 10.1111/ijd.17592

Rhea Ahuja, Aysha Najeeb, Ananya Sharma, Sudheer Arava, Neha Taneja

引用次数: 0

AI and epigenetics: new approaches to skin aging understanding and treatment. 人工智能和表观遗传学：了解和治疗皮肤老化的新方法。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-11-29 DOI: 10.1111/ijd.17593

Marina Landau, Martin Kassir, Mohamad Goldust

引用次数: 0

Cost-efficiency of excision and non-excision-based keratoacanthoma treatment modalities. 角膜棘瘤切除术和非切除术治疗方式的成本效益。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-11-28 DOI: 10.1111/ijd.17587

David X Gao, David M Ozog, Jalal Maghfour, Qing-Sheng Mi, Jesse Veenstra

引用次数: 0

External validation study of Re-SCORTEN in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. 针对史蒂文斯-约翰逊综合征和中毒性表皮坏死症患者的 Re-SCORTEN 外部验证研究。

IF 3.5 4区医学

International Journal of Dermatology Pub Date : 2024-11-26 DOI: 10.1111/ijd.17584

Mike Westmeijer, Joseph Ebriani, Beatrix B Thompson, Allison Holt, Bethany Brumbaugh, Kevin Sheng-Kai Ma, Arash Mostaghimi, Steven T Chen

引用次数: 0