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International Journal of Dermatology最新文献

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Beneficial Therapeutic Effect of Endothelin-Receptor Antagonist in Generalized Morphea: A Report of Two Cases. 内皮素受体拮抗剂治疗广泛性睡眠的有益疗效：附2例报告。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-13 DOI: 10.1111/ijd.17900
Leticia Szadai, Nóra Belső, Daniella Hulló, Erika Varga, Irma Korom, Zsuzsanna Bata-Csörgö
{"title":"Beneficial Therapeutic Effect of Endothelin-Receptor Antagonist in Generalized Morphea: A Report of Two Cases.","authors":"Leticia Szadai, Nóra Belső, Daniella Hulló, Erika Varga, Irma Korom, Zsuzsanna Bata-Csörgö","doi":"10.1111/ijd.17900","DOIUrl":"https://doi.org/10.1111/ijd.17900","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Dapsone Conundrum: Understanding Implications of Adverse Reactions to Dapsone Including Dapsone Hypersensitivity Syndrome in Leprosy Patients Treated With Multidrug Therapy. 氨苯砜难题：了解多药治疗麻风病患者氨苯砜不良反应的含义，包括氨苯砜过敏综合征。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-13 DOI: 10.1111/ijd.17906
Anubha Dev, Tarun Narang, Vishal Thakur, Sunil Dogra
{"title":"The Dapsone Conundrum: Understanding Implications of Adverse Reactions to Dapsone Including Dapsone Hypersensitivity Syndrome in Leprosy Patients Treated With Multidrug Therapy.","authors":"Anubha Dev, Tarun Narang, Vishal Thakur, Sunil Dogra","doi":"10.1111/ijd.17906","DOIUrl":"https://doi.org/10.1111/ijd.17906","url":null,"abstract":"<p><strong>Background: </strong>The introduction of the World Health Organization's multidrug therapy (WHO-MDT) has significantly advanced leprosy treatment. Although dapsone is a fundamental component of MDT, it presents risks of adverse drug reactions (ADR), including the potentially fatal dapsone hypersensitivity syndrome (DHS).</p><p><strong>Methods: </strong>Consequently, we conducted a retrospective observational study by reviewing the records of patients registered at the leprosy clinic within the department of dermatology at a tertiary care center from 2010 to 2022. We included all patients who experienced ADR due to dapsone that necessitated its discontinuation, with particular emphasis on those who developed DHS.</p><p><strong>Results: </strong>Among 1598 leprosy patients treated with standard WHO-MDT, 45 patients developed ADR requiring cessation of dapsone (2.82% over 12 years). The most common ADR was abnormal liver function tests in 14 patients (0.87%) and anemia in 13 patients (0.81%), including one case each of hemolytic anemia and methemoglobinemia. Neuropsychiatric adverse effects were observed in five patients (0.31%). The incidence of DHS was 0.75% (12 patients), with maculopapular rash being the most frequent cutaneous manifestation. These patients were subsequently treated with MDT without dapsone, along with standard care for the ADR, resulting in no mortality or serious morbidity.</p><p><strong>Conclusion: </strong>While dapsone remains a cornerstone in the treatment of leprosy, the potential for clinically significant though infrequent adverse reactions highlights the need for vigilant monitoring and increased awareness among healthcare providers of the diverse manifestations of dapsone-related side effects.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Efficacy of Dupilumab in Pemphigus Vulgaris. 杜匹单抗治疗寻常型天疱疮的疗效观察。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-13 DOI: 10.1111/ijd.17902
Foday Koroma, Shivkar Amara, Mark Lebwohl
{"title":"The Efficacy of Dupilumab in Pemphigus Vulgaris.","authors":"Foday Koroma, Shivkar Amara, Mark Lebwohl","doi":"10.1111/ijd.17902","DOIUrl":"https://doi.org/10.1111/ijd.17902","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Uncommon Perianal Mass in a Girl: A Diagnostic Challenge. 一个不寻常的女孩肛周肿块：诊断的挑战。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-13 DOI: 10.1111/ijd.17911
Sonika Garg, Nita Khurana, Vishal Gaurav
{"title":"An Uncommon Perianal Mass in a Girl: A Diagnostic Challenge.","authors":"Sonika Garg, Nita Khurana, Vishal Gaurav","doi":"10.1111/ijd.17911","DOIUrl":"https://doi.org/10.1111/ijd.17911","url":null,"abstract":"<p><p>A 15-year-old female presented with a two-month history of a tender perianal nodule, which was aggravated by sitting or pressure. She denied having any systemic symptoms. Examination revealed a well-defined, erythematous-to-gray nodule measuring 3 × 3 cm, featuring a corrugated surface at the lateral end. Histopathology showed large polygonal cells with abundant granular eosinophilic cytoplasm and small, uniform nuclei. Immunohistochemical staining was strongly positive for S-100 protein and neuron-specific enolase, confirming the diagnosis of a granular cell tumor (GCT). GCT is a rare, usually benign neoplasm of Schwann cell origin, with perianal involvement being extremely uncommon, especially in pediatric patients. Although most cases are asymptomatic, a perianal GCT can cause discomfort and may require surgical excision with sphincter preservation. While malignant transformation is rare, close monitoring is advised. This case highlights the diagnostic challenges of GCT in unusual locations and underscores the importance of histopathology and immunohistochemistry for accurate diagnosis and management.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Equity in the Surgical Treatment of Melanoma In Situ: A Call for Greater Vigilance. 原位黑色素瘤手术治疗的公平性：提高警惕的呼吁。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-13 DOI: 10.1111/ijd.17914
Henry O Herrera, Roy Mendoza, Daniel Novak, Jeremy S Bordeaux, Ashley Elsensohn
{"title":"Equity in the Surgical Treatment of Melanoma In Situ: A Call for Greater Vigilance.","authors":"Henry O Herrera, Roy Mendoza, Daniel Novak, Jeremy S Bordeaux, Ashley Elsensohn","doi":"10.1111/ijd.17914","DOIUrl":"https://doi.org/10.1111/ijd.17914","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
En Coup D'une Veine: Anatomy of a Novel Morphea Mimicker. 《青葱妙计：剖析一个新颖的梦中人》。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-13 DOI: 10.1111/ijd.17875
Chavely Calderon-Casellas, Hannah Mumber, Dylan R Waterman, Eugene Y Kissin, William A Mehan, Michael R York, Christina S Lam
{"title":"En Coup D'une Veine: Anatomy of a Novel Morphea Mimicker.","authors":"Chavely Calderon-Casellas, Hannah Mumber, Dylan R Waterman, Eugene Y Kissin, William A Mehan, Michael R York, Christina S Lam","doi":"10.1111/ijd.17875","DOIUrl":"https://doi.org/10.1111/ijd.17875","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Problem of Antimicrobial Resistance in Scabies: An Emerging Public Health Threat. 疥疮抗菌素耐药性问题：一个新出现的公共卫生威胁。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-13 DOI: 10.1111/ijd.17919
Andrea Zovi, Francesco Ferrara, Roberto Langella, Antonio Vitiello
{"title":"The Problem of Antimicrobial Resistance in Scabies: An Emerging Public Health Threat.","authors":"Andrea Zovi, Francesco Ferrara, Roberto Langella, Antonio Vitiello","doi":"10.1111/ijd.17919","DOIUrl":"https://doi.org/10.1111/ijd.17919","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Vitamin D3 Supplementation as an Adjunct to Bilastine 40 mg in Chronic Spontaneous Urticaria Patients With Vitamin D3 Deficiency: A Randomized, Double-Blind, Placebo-Controlled Study. 补充维生素D3辅助Bilastine 40mg治疗维生素D3缺乏的慢性自发性荨麻疹患者的疗效：一项随机、双盲、安慰剂对照研究
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-12 DOI: 10.1111/ijd.17897
Abhishek De, Disha Chakraborty, S K Shahriyar Ahmed, Kiran Godse
{"title":"Efficacy of Vitamin D3 Supplementation as an Adjunct to Bilastine 40 mg in Chronic Spontaneous Urticaria Patients With Vitamin D3 Deficiency: A Randomized, Double-Blind, Placebo-Controlled Study.","authors":"Abhishek De, Disha Chakraborty, S K Shahriyar Ahmed, Kiran Godse","doi":"10.1111/ijd.17897","DOIUrl":"https://doi.org/10.1111/ijd.17897","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidermolysis Bullosa Acquisita due to Epitope Spreading in a Patient With Recurrent Bullous Pemphigoid. 复发性大疱性类天疱疮患者表位扩散所致的大疱性获得性表皮松解。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-12 DOI: 10.1111/ijd.17907
Daponte Athina-Ioanna, Tsitlakidou Anastasia, Tsaousi Athanasia, Meltzanidou Parthena, Kyriakou Aikaterini, Giannakou Anastasia, Lazaridou Elizabeth, Patsatsi Aikaterini
{"title":"Epidermolysis Bullosa Acquisita due to Epitope Spreading in a Patient With Recurrent Bullous Pemphigoid.","authors":"Daponte Athina-Ioanna, Tsitlakidou Anastasia, Tsaousi Athanasia, Meltzanidou Parthena, Kyriakou Aikaterini, Giannakou Anastasia, Lazaridou Elizabeth, Patsatsi Aikaterini","doi":"10.1111/ijd.17907","DOIUrl":"https://doi.org/10.1111/ijd.17907","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hoarseness and Dysphagia in PKDL: Expanding the Clinical Spectrum of a Neglected Tropical Disease. PKDL的声音嘶哑和吞咽困难：扩展了一种被忽视的热带病的临床谱。
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-06-12 DOI: 10.1111/ijd.17901
Sejal Jain, Hitaishi Mehta, Debajyoti Chatterjee, Prerna Angrish, Nishita Yadav, Tarun Narang
{"title":"Hoarseness and Dysphagia in PKDL: Expanding the Clinical Spectrum of a Neglected Tropical Disease.","authors":"Sejal Jain, Hitaishi Mehta, Debajyoti Chatterjee, Prerna Angrish, Nishita Yadav, Tarun Narang","doi":"10.1111/ijd.17901","DOIUrl":"https://doi.org/10.1111/ijd.17901","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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