{"title":"Skin Testing for the Detection of Rituximab Hypersensitivity in a Pediatric Case of Pemphigus Vulgaris.","authors":"Arun Somasundaram, Anubhab Bhattacharyya, Newshree Rout, Shivani Mundoor Dayakar, Malathi Munisamy","doi":"10.1111/ijd.70444","DOIUrl":"https://doi.org/10.1111/ijd.70444","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Misdiagnosis of Pemphigus Foliaceus as Psoriasis.","authors":"Kateryna Karpoff, Omar Alani, Mark Lebwohl","doi":"10.1111/ijd.70467","DOIUrl":"https://doi.org/10.1111/ijd.70467","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatima Bawany, Derek Maas, Mackenzie R Martin, Zasca-Aisha Ristianto, Daniel R Mazori
{"title":"Reimagining Dermatology Simulation: A Call for Greater Skin Color Representation in Suture Pads and Beyond.","authors":"Fatima Bawany, Derek Maas, Mackenzie R Martin, Zasca-Aisha Ristianto, Daniel R Mazori","doi":"10.1111/ijd.70459","DOIUrl":"https://doi.org/10.1111/ijd.70459","url":null,"abstract":"<p><p>Simulation is a cornerstone of medical education, but do training materials reflect the diversity of the patients they are meant to simulate? This viewpoint examines the underrepresentation of skin tones in dermatology simulation materials, explores the desire among learners to train with inclusive equipment, and calls for more representative resources.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Sechi, Michela Starace, Luca Valtellini, Francesca Pampaloni, Bianca Maria Piraccini, Antonella Tosti, Matilde Iorizzo
{"title":"Beyond the Plate: Nail Bed Dermoscopy for Differentiation of Psoriatic, Fungal, and Traumatic Fingernail Onycholysis.","authors":"Andrea Sechi, Michela Starace, Luca Valtellini, Francesca Pampaloni, Bianca Maria Piraccini, Antonella Tosti, Matilde Iorizzo","doi":"10.1111/ijd.70449","DOIUrl":"https://doi.org/10.1111/ijd.70449","url":null,"abstract":"<p><strong>Background: </strong>Onycholysis is a common but etiologically heterogeneous nail sign, most frequently due to psoriasis, onychomycosis, and trauma. Since the diagnosis of the underlying cause can be misleading, we investigated whether dermoscopy (onychoscopy) pre- and post-clipping of the onycholytic nail plate can provide reproducible patterns to distinguish these causes without the need for a biopsy.</p><p><strong>Materials and methods: </strong>In a multicenter retrospective image-based study, 60 onycholytic fingernails were examined (20 patients per diagnosis: psoriasis, onychomycosis, trauma). Onychoscopy of the intact plate was followed by clipping of the detached nail plate and dermoscopic assessment of the exposed nail bed under both dry and wet conditions. Color, amount, thickness, adherence, mobility (\"wet test\"), and distribution of subungual scales were recorded. Multinomial logistic regression assessed independent associations between dermoscopic features and diagnostic categories.</p><p><strong>Results: </strong>After clipping, dermoscopy revealed distinct nail-bed patterns. Psoriasis showed a high scale amount (65%), white color (95%), thick (90%), strongly adherent (95%), and immobile scales (95%). Onychomycosis showed a moderate/high scale amount (95%), yellow/yellow-white color (90%), reduced adherence (80%), and mobility (65); when compared with psoriasis it showed higher odds of moderate-to-low scale amount (odds ratio [OR] 7.19), yellowish color (OR 6.02), reduced adherence (OR 75.19), and wet-test mobility (OR for absence 0.026). Trauma showed a low scale amount (75%), thin (85%), loosely adherent (65%), mobile scales (60%), and showed increased odds of reduced amount (OR 13.34), yellowish color (OR 7.15), and reduced adherence (OR 80.95).</p><p><strong>Conclusions: </strong>Combining pre- and post-clipping nail dermoscopy improves differentiation of psoriatic, onychomycotic, and traumatic onycholysis, supporting post-clipping nail bed dermoscopy as a simple adjunct that enhances diagnostic accuracy and management.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acne Lesions Induced by Oral JAK Inhibitors Include Comedones: Insights From Six Patients Without Any Prior History of Acne.","authors":"Sarina Ban, Itaru Dekio, Mina Kaneshiro, Yoshimasa Nobeyama, Yoshiyuki Murakami, Akihiko Asahina","doi":"10.1111/ijd.70450","DOIUrl":"https://doi.org/10.1111/ijd.70450","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Divya M Shan, Aaron D Smith, Catherine E Lyons, Hope Winfield, Samuel Soon, Rasha Alsaadawi, R Hal Flowers
{"title":"Assessing the Impact of Financial Toxicity on Quality of Life in Patients With Hidradenitis Suppurativa: A Cross-Sectional Survey Study.","authors":"Divya M Shan, Aaron D Smith, Catherine E Lyons, Hope Winfield, Samuel Soon, Rasha Alsaadawi, R Hal Flowers","doi":"10.1111/ijd.70454","DOIUrl":"https://doi.org/10.1111/ijd.70454","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selective IL-23 Inhibition in Pyoderma Gangrenosum: Promise, Questions, and Next Steps.","authors":"Uwe Wollina","doi":"10.1111/ijd.70458","DOIUrl":"https://doi.org/10.1111/ijd.70458","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral Versus Injectable Therapies in Psoriasis: Beyond Route to Molecular Modality and Pharmacologic Determinants.","authors":"Michael H Gold, Mohamad Goldust","doi":"10.1111/ijd.70461","DOIUrl":"https://doi.org/10.1111/ijd.70461","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Orbital Gouty Tophus Masquerading as a Periocular Cyst: An Initial Manifestation of Gout.","authors":"Marc A Hill, Laura Xiang, Kenneth Tomecki","doi":"10.1111/ijd.70457","DOIUrl":"https://doi.org/10.1111/ijd.70457","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evidence of Increased 3-Alpha-Androstanediol Glucuronide in Female Pattern Alopecia: A Cross-Sectional Observational Study Evaluating Ovarian, Adrenal, and Peripheral Androgens.","authors":"Arunesh Padmini Kathirvelu, Kabir Sardana, Lokesh Kumar Sharma, Ananta Khurana, Savitha Sharath","doi":"10.1111/ijd.70445","DOIUrl":"https://doi.org/10.1111/ijd.70445","url":null,"abstract":"<p><strong>Background: </strong>The role of androgens in female pattern hair loss (FPHL) is disputed as patients usually have normal androgen levels. 3α-androstanediol glucuronide (3α-diol G) is a marker of peripheral hyperandrogenism, but has not been assessed in FPHL. We aimed to evaluate ovarian, adrenal, and peripheral (3α-diol G) androgens in Indian women with FPHL and correlate them with the clinical severity of FPHL.</p><p><strong>Methods: </strong>A cross-sectional observational study was conducted at a tertiary care hospital in India, involving 44 women with trichoscopically confirmed FPHL and 30 age-matched healthy controls. Clinical severity was graded using the Ludwig and Sinclair scales. Serum total testosterone (tT), SHBG, free androgen index, AMH, DHEAS, LH, FSH, TSH, prolactin, and 3α-diol G were measured.</p><p><strong>Results: </strong>FPHL patients presented with Ludwig grade 1 (70%, n = 31) and Ludwig grade 2 (29.5%, n = 13). Serum 3α-diol G levels were significantly higher in FPHL (mean: 8.43 ± 4.44 nmol/L, range: 3.2-20.74 nmol/L) compared to controls (mean: 4.23 ± 1.39 nmol/L, range: 1.81-7.29 nmol/L; p < 0.001). Levels of other androgens and pre-androgens were not significantly different between the groups. Abnormal tT levels (6.8%, n = 3) and DHEAS (4.5%, n = 2) were seen in a minority of cases. There was a positive correlation of 3α-diol G with FPHL severity (Ludwig scale, Spearman's ρ = 0.37, p = 0.013), with receiver operating characteristics (ROC) analysis revealing a high diagnostic accuracy (AUROC 0.85; cut-off ≥ 5.242 nmol/L; 82% sensitivity, 73% specificity) as compared to other hormonal parameters.</p><p><strong>Conclusion: </strong>Serum 3α-diol G is a promising biomarker of peripheral hyperandrogenism in FPHL and correlates with clinical severity and may help in monitoring antiandrogen therapy.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}