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International Journal of Dermatology最新文献

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Prostaglandins and Skin Cancer: An Old Pathway With New Insights in Cutaneous Oncology.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-04-01 DOI: 10.1111/ijd.17771
Krisztian Nemeth
{"title":"Prostaglandins and Skin Cancer: An Old Pathway With New Insights in Cutaneous Oncology.","authors":"Krisztian Nemeth","doi":"10.1111/ijd.17771","DOIUrl":"https://doi.org/10.1111/ijd.17771","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive Literature Review Evaluating the Use, Safety, and Efficacy of Subcutaneous Methotrexate in the Treatment of Adult Patients With Moderate-To-Severe Plaque-Type Psoriasis.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-04-01 DOI: 10.1111/ijd.17758
Manuelle Viguier, José-Manuel Carrascosa-Carrillo, Pariyawan Rakvit, Maria-Magdalena Constantin, Alice-Anaïs Varlet, Solenn Le Clanche, Linda A W Verhagen, Wolf-Henning Boehncke
{"title":"Comprehensive Literature Review Evaluating the Use, Safety, and Efficacy of Subcutaneous Methotrexate in the Treatment of Adult Patients With Moderate-To-Severe Plaque-Type Psoriasis.","authors":"Manuelle Viguier, José-Manuel Carrascosa-Carrillo, Pariyawan Rakvit, Maria-Magdalena Constantin, Alice-Anaïs Varlet, Solenn Le Clanche, Linda A W Verhagen, Wolf-Henning Boehncke","doi":"10.1111/ijd.17758","DOIUrl":"https://doi.org/10.1111/ijd.17758","url":null,"abstract":"<p><p>Methotrexate (MTX) is a conventional systemic therapy widely used to treat chronic plaque-type psoriasis, a chronic inflammatory skin disease that significantly impacts patients' quality of life. MTX can be administered orally or subcutaneously. Over the past decades, the use of subcutaneous versus oral MTX has been a subject of ongoing debate among dermatologists. Therefore, this literature review aimed to investigate the differences between oral and subcutaneous MTX described in the scientific literature in terms of intestinal absorption and bioavailability, efficacy, safety, patient satisfaction and quality of life, treatment adherence, and economic outlook. Thirty-two articles were included in the review, notably including evidence-based guidelines on the management of psoriasis, as well as randomized clinical trials and real-world studies. Only European guidelines recommend the use of subcutaneous MTX over oral MTX; hence, the use of subcutaneous MTX is reported almost exclusively in European countries. Despite the paucity and heterogeneity of the literature, findings from the review suggest that subcutaneous MTX may overcome some limitations of the oral route in terms of intestinal absorption, bioavailability, and safety. Moreover, subcutaneous MTX may provide higher efficacy with a faster, or even greater, response in psoriatic patients and better adherence to treatment. In conclusion, subcutaneous MTX tends to be advantageous with regard to psoriasis management, similar to other chronic inflammatory diseases like rheumatoid arthritis; however, this comes with a higher cost. The treatment of psoriasis using subcutaneous MTX deserves further study, especially in the biologics age.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Unexpected Successful Treatment of Alopecia Areata With Tralokinumab in a Patient With Atopic Dermatitis.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-03-28 DOI: 10.1111/ijd.17755
Jacqueline Kussini, Wolfgang Pfützner, Stefan Mühlenbein
{"title":"A Case of Unexpected Successful Treatment of Alopecia Areata With Tralokinumab in a Patient With Atopic Dermatitis.","authors":"Jacqueline Kussini, Wolfgang Pfützner, Stefan Mühlenbein","doi":"10.1111/ijd.17755","DOIUrl":"https://doi.org/10.1111/ijd.17755","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human Papillomavirus Vaccination Prevalence and Differences in Recent Risky Behavior Between Ukrainian Females From 18 to 26 and 27 to 45-Year-Old Cohorts.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-03-28 DOI: 10.1111/ijd.17761
Pavel V Chernyshov, Tetiana Osaulenko, Yulia V Zolotonosha, Daria Turchak
{"title":"Human Papillomavirus Vaccination Prevalence and Differences in Recent Risky Behavior Between Ukrainian Females From 18 to 26 and 27 to 45-Year-Old Cohorts.","authors":"Pavel V Chernyshov, Tetiana Osaulenko, Yulia V Zolotonosha, Daria Turchak","doi":"10.1111/ijd.17761","DOIUrl":"https://doi.org/10.1111/ijd.17761","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Snakes and Skin: A Review of Aesthetic, Analgesic, and Anesthetic Snake Venom Applications.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-03-28 DOI: 10.1111/ijd.17760
Elena E Skaribas, Alisha Kashyap, T Austin Black, Noel Yang, Iman Ali, Rashid M Rashid
{"title":"Snakes and Skin: A Review of Aesthetic, Analgesic, and Anesthetic Snake Venom Applications.","authors":"Elena E Skaribas, Alisha Kashyap, T Austin Black, Noel Yang, Iman Ali, Rashid M Rashid","doi":"10.1111/ijd.17760","DOIUrl":"https://doi.org/10.1111/ijd.17760","url":null,"abstract":"<p><p>Snake venoms contain a diverse array of organic compounds, including potent neurotoxins and cytotoxins known for inducing neurologic impairment and cellular damage. Despite these dangers, several medications derived from snake venom have gained Food and Drug Administration (FDA) approval, marking significant advancements in therapeutic applications. Notably, neurotoxins have garnered attention in pain research due to their demonstrated analgesic and anesthetic properties, offering potential benefits in dermatological disorders associated with pain symptoms. Recent murine studies of snake-derived neurotoxins such as mambalgin-1, mambalgin-2, crotamine, and cobrotoxin have shown efficacy in alleviating neuropathic and chronic pain, often outperforming traditional analgesics like morphine, with fewer adverse effects reported. Limited applications of these venom components in humans, including local injections for the treatment of neuropathic pain and inflammation, have yielded encouraging findings through observational studies. Beyond pain relief, snake venom's benefits also extend to anti-aging treatments through their paralytic effects, with synthetic neurotoxins now available in various cosmetic products. This review explores the advancements in snake venom-based therapies, focusing on their analgesic, anesthetic, and aesthetic properties in the treatment of dermatological conditions.</p>","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stool Biomarkers as a Clue for Developing Crohn's Disease in Idiopathic Pyoderma Gangrenosum Patients.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-03-26 DOI: 10.1111/ijd.17703
Marwan Dawood, Ziad Khamaysi, Emily Avitan-Hersh
{"title":"Stool Biomarkers as a Clue for Developing Crohn's Disease in Idiopathic Pyoderma Gangrenosum Patients.","authors":"Marwan Dawood, Ziad Khamaysi, Emily Avitan-Hersh","doi":"10.1111/ijd.17703","DOIUrl":"https://doi.org/10.1111/ijd.17703","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atopic Dermatitis in Indonesian Children: Association of Toilet Seat Dermatitis With Moderate-Severe Manifestation and Low Prevalence of Loss-of-Function Filaggrin Gene Variants.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-03-24 DOI: 10.1111/ijd.17733
Raden Mohamad Rendy Ariezal Effendi, Luba M Pardo, Reiva Farah Dwiyana, Oki Suwarsa, Michel van Geel, Yunia Sribudiani, Tamar E C Nijsten, Hok Bing Thio
{"title":"Atopic Dermatitis in Indonesian Children: Association of Toilet Seat Dermatitis With Moderate-Severe Manifestation and Low Prevalence of Loss-of-Function Filaggrin Gene Variants.","authors":"Raden Mohamad Rendy Ariezal Effendi, Luba M Pardo, Reiva Farah Dwiyana, Oki Suwarsa, Michel van Geel, Yunia Sribudiani, Tamar E C Nijsten, Hok Bing Thio","doi":"10.1111/ijd.17733","DOIUrl":"https://doi.org/10.1111/ijd.17733","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chest Wall Phaeohyphomycosis in a Child With Lepromatous Leprosy.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-03-24 DOI: 10.1111/ijd.17735
Jain Ayush, Verma Vaishnavi, M Ramam, Sahni Kanika
{"title":"Chest Wall Phaeohyphomycosis in a Child With Lepromatous Leprosy.","authors":"Jain Ayush, Verma Vaishnavi, M Ramam, Sahni Kanika","doi":"10.1111/ijd.17735","DOIUrl":"https://doi.org/10.1111/ijd.17735","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Familial Inflammatory Diseases and Hidradenitis Suppurativa Severity: A Single-Center Study.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-03-24 DOI: 10.1111/ijd.17747
Defne Özkoca, Adil Özcanlı, Elif Er Gülbezer, Nazmiye Selin Salıcı, Savaş Yaylı, Seçil Vural
{"title":"Association Between Familial Inflammatory Diseases and Hidradenitis Suppurativa Severity: A Single-Center Study.","authors":"Defne Özkoca, Adil Özcanlı, Elif Er Gülbezer, Nazmiye Selin Salıcı, Savaş Yaylı, Seçil Vural","doi":"10.1111/ijd.17747","DOIUrl":"https://doi.org/10.1111/ijd.17747","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting the Cutibacterium acnes Biofilm in Acne.
IF 3.5 4区 医学
International Journal of Dermatology Pub Date : 2025-03-22 DOI: 10.1111/ijd.17752
Emma Scott, George S Bullerjahn, Craig G Burkhart
{"title":"Targeting the Cutibacterium acnes Biofilm in Acne.","authors":"Emma Scott, George S Bullerjahn, Craig G Burkhart","doi":"10.1111/ijd.17752","DOIUrl":"https://doi.org/10.1111/ijd.17752","url":null,"abstract":"","PeriodicalId":13950,"journal":{"name":"International Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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