International Journal of Artificial Organs最新文献

{"title":"Therapeutic plasma exchange added to CRRT combined with hemoperfusion in wasp sting-associated AKI: A multicenter retrospective cohort study.","authors":"Rong Li, Nan Huang, Dongju Zhang, Chunyan Song, Zhishuang Zhai, Xiaoli Cheng, Jing Wang, Peng Zhang","doi":"10.1177/03913988261456903","DOIUrl":"10.1177/03913988261456903","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate whether adding therapeutic plasma exchange (PE) to continuous renal replacement therapy plus hemoperfusion (CRRT + HP) could improve renal recovery with wasp sting-associated acute kidney injury (AKI).</p><p><strong>Methods: </strong>We conducted a multicenter retrospective cohort study in three tertiary hospitals in the Qinling region of China (July 2015-December 2024). Patients received either CRRT + HP or CRRT + HP + PE within a 72-h exposure window. The primary endpoint was renal recovery, which was analyzed in a competing-risk framework with death as the competing event. Cumulative incidence of renal recovery were compared using Gray's test, and fine-Gray models estimated subdistribution hazard ratios (sHR). Longitudinal changes in key laboratory variables and SOFA scores were assessed with linear mixed-effects models.</p><p><strong>Results: </strong>Among 176 eligible patients (CRRT + HP, <i>n</i> = 103; CRRT + HP + PE, <i>n</i> = 73), baseline severity was higher in the PE group before matching but was well balanced after propensity score matching. In the matched cohort, the CRRT + HP+PE group had a higher 30 days cumulative incidence of renal recovery than CRRT + HP (54.2% vs 32.2%). Overall renal recovery CIF curves favored CRRT + HP+PE (Gray's test, χ² = 6.277, <i>p</i> = 0.0122). In univariable fine-Gray analysis, PE was associated with increased renal recovery (sHR = 1.56, 95% CI 1.07-2.27; <i>p</i> = 0.021), and the association remained significant after multivariable adjustment (sHR 3.97, 95% CI 1.59-10.08; <i>p</i> < 0.001). 90-day mortality was numerically lower with PE but not statistically significant. Serum creatinine, total bilirubin, and SOFA score trajectories were improved faster in the CRRT + HP + PE group.</p><p><strong>Conclusions: </strong>For patients with AKI caused by wasp stings, the addition of PE to CRRT + HP can improve early renal recovery and yield more favorable laboratory trajectories.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"679-688"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foot care behaviors and perceived exercise benefits and barriers in diabetic hemodialysis patients.","authors":"Medine Yucesoy Isler, Elif Bulbul","doi":"10.1177/03913988261455770","DOIUrl":"10.1177/03913988261455770","url":null,"abstract":"<p><strong>Purpose: </strong>To examine foot care behaviors, perceived benefits and barriers to exercise, and the relationships between these factors among diabetic patients undergoing hemodialysis.</p><p><strong>Major findings: </strong>This study included 151 adults with type 2 diabetes receiving hemodialysis in Istanbul. Data were collected using the Foot Care Behavior Scale, the Diabetic Foot Care Self-Efficacy Scale, and the Exercise Benefits/Barriers Scale for Dialysis Patients. Descriptive statistics, <i>t</i>-tests, ANOVA, correlation analyses, and linear regression were conducted. Higher education and health literacy were associated with improved foot care behaviors and greater perceived benefits of exercise. Fatigue, comorbidities, and lack of knowledge were identified as major barriers to exercise. Regression analysis showed that gender, age, albumin level, and exercise status significantly influenced perceived benefits and barriers.</p><p><strong>Conclusions: </strong>Nursing interventions should focus on patient education, strengthening self-efficacy, and providing individualized exercise guidance to improve outcomes among diabetic hemodialysis patients. These findings highlight the critical role of nurses in promoting self-care behaviors and physical activity among diabetic hemodialysis patients.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"689-696"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of clinical characteristics to mortality in acute respiratory failure patients treated with ECCO₂R.","authors":"Ravindranath Tiruvoipati, Alexandra May, Ary Serpa Neto, Bindu Akkanti, Kha Dinh, Nicholas A Barrett, Steven A Conrad","doi":"10.1177/03913988261461123","DOIUrl":"10.1177/03913988261461123","url":null,"abstract":"<p><strong>Background: </strong>Low flow extracorporeal carbon dioxide removal (ECCO₂R) is used to assist in lung protective ventilation. The objective of this study was to compare the characteristics of patients who died in-hospital to those who survived and identify variables pre and during the first 24 h of ECCO₂R support independently associated with hospital mortality.</p><p><strong>Methods: </strong>This study is a multicenter, multinational, retrospective review of data from the Hemolung Registry between April 2013 and June 2021. The primary outcome was hospital mortality.</p><p><strong>Results: </strong>Of the 242 included patients 115 (48%) survived. Prior to ECCO₂R initiation and during the first 24 h of ECCO₂R therapy, patients who died had a lower PaO₂/FiO₂ ratio but higher FiO₂, respiratory rate (RR), and tidal volumes. Age ((OR: 1.51 (95% CI: 1.06-2.14); <i>p</i> = 0.022), RR (1.92 (1.28-2.87); <i>p</i> = 0.002), and FiO₂ (2.33 (1.50-3.62); <i>p</i> < 0.001) were independently associated with increased risk of mortality.</p><p><strong>Conclusions: </strong>Age, respiratory rate, and FiO₂ during the first 24 h of ECCO₂R therapy were independently associated with increased risk of hospital mortality. An ongoing high FiO₂ (>0.7) and respiratory rate ⩾25 during the first 24 h is independently associated with higher risk of hospital mortality.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"725-734"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148411762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Larger balloon diameter improves vascular resistance in arteriovenous access: A retrospective analysis.","authors":"Takahiro Tamaki, Keita Hattori, Isao Mizusaki, Kazunori Ikeba, Hiroki Ito, Takeshi Ito, Saori Tsukushi","doi":"10.1177/03913988261451737","DOIUrl":"10.1177/03913988261451737","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous transluminal angioplasty (PTA) effectively treats hemodialysis access stenosis; however, restenosis remains common, partly due to variability in balloon diameter selection. To address this issue, we evaluated the utility of a simple +1-mm upsizing strategy using the same balloon type.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at Tokai Central Hospital between September 2021 and August 2025. We analyzed 17 PTA procedures in 15 maintenance hemodialysis patients who underwent regularly scheduled PTA for recurrent stenosis. To minimize device-related variability, only sessions in which the same balloon type was used and upsized by +1 mm were included. Vascular resistance, blood flow, and vessel diameter were assessed by duplex ultrasonography following a standardized protocol.</p><p><strong>Results: </strong>No adverse events occurred. Balloon upsizing significantly improved vascular resistance and vessel diameter, demonstrated a trend toward increased blood flow, and showed a tendency to prolong the interval between PTA sessions.</p><p><strong>Conclusions: </strong>A +1-mm balloon upsizing strategy improves hemodynamics without increasing complications and may represent a safe, practical enhancement to PTA management of hemodialysis access.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"697-705"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148198799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between mechanical ventilation duration and maternal-neonatal factors in critically ill neonates: A retrospective study.","authors":"Zulin Lu, Lifang Zhao, Ying Liu, Wei Fu, Jiuye Guo, Yueqiao Gao","doi":"10.1177/03913988261455780","DOIUrl":"10.1177/03913988261455780","url":null,"abstract":"<p><strong>Objective: </strong>To examine the associations between neonatal-maternal characteristics and mechanical ventilation duration in critically ill neonates, and to explore differences between respiratory distress syndrome (RDS) and non-RDS subgroups.</p><p><strong>Methods: </strong>This retrospective study included 319 neonates who required mechanical ventilation in the neonatal intensive care unit of our hospital between 1 January 2022 and 31 December 2024. Data on neonatal demographics, Apgar scores, initial arterial blood gas parameters and maternal characteristics, including age, delivery mode and comorbidities, were collected. The primary outcome was total ventilation duration. Correlation and subgroup analyses were performed.</p><p><strong>Results: </strong>The median duration of total mechanical ventilation (invasive + non-invasive) was 133.0 (interquartile range (IQR): 146.0) h. All neonates received invasive mechanical ventilation with a median duration of 48.0 (IQR: 58.0) h, and 83.7% subsequently required non-invasive ventilation support. Ventilation duration was negatively correlated with gestational age (<i>r</i> = -0.503, <i>p</i> < 0.001) and birth weight (<i>r</i> = -0.473, <i>p</i> < 0.001) and positively correlated with blood pH (<i>r</i> = 0.142, <i>p</i> = 0.011), using PS (<i>r</i> = 0.439, <i>p</i> < 0.001) and bicarbonate (<i>r</i> = 0.141, <i>p</i> = 0.012). No significant associations were found with Apgar scores, lactate or maternal age. Compared with non-RDS neonates, those with RDS had significantly longer ventilation durations (135.0 (IQR: 147.0) vs 73.5 (IQR: 100.8) h, <i>p</i> < 0.001), as well as lower gestational age and birth weight, altered blood gas parameters and a higher rate of caesarean deliveries (all <i>p</i> < 0.05). Maternal comorbidity rates did not differ significantly between the groups (<i>p</i> > 0.05). The results of multivariate regression analysis showed that the independent factors affecting mechanical ventilation time were gestational age, pulmonary surfactant, birth weight, blood pH, HCO₃^- and mode of delivery.</p><p><strong>Conclusions: </strong>Neonatal factors, especially gestational age and birth weight, critically impact ventilation duration in critically ill neonates. Tailored respiratory management addressing diagnosis and key perinatal factors (gestational age, birth weight) may improve outcomes.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"706-714"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health literacy, self-management, and patient empowerment in hemodialysis patients: A cross-sectional study.","authors":"Sude N Ölmez, Gülay Turgay","doi":"10.1177/03913988261473831","DOIUrl":"10.1177/03913988261473831","url":null,"abstract":"<p><strong>Background: </strong>Hemodialysis requires patients to maintain complex and lifelong self-care behaviors. Health literacy, self-management, and patient empowerment are key components of effective care, yet their combined roles in hemodialysis populations remain unclear. This study aimed to evaluate these constructs and examine their interrelationships in patients receiving hemodialysis.</p><p><strong>Methods: </strong>This cross-sectional study included 219 patients from three dialysis centers between January and May 2024. Data were collected using validated scales assessing health literacy, self-management, and patient empowerment. Analyses included descriptive statistics, Pearson correlation, and multivariable linear regression.</p><p><strong>Results: </strong>Participants had above-midpoint mean scores for health literacy, self-management, and patient empowerment. Health literacy was positively associated with patient empowerment and health maintenance efficacy, and negatively associated with self-stigmatization. Age was negatively associated with health literacy, whereas higher education was positively associated with both health literacy and patient empowerment. No significant predictors were identified for self-management.</p><p><strong>Conclusions: </strong>Health literacy, self-management, and patient empowerment are interrelated in patients receiving hemodialysis. Health literacy showed consistent associations with patient empowerment and selected aspects of self-management, whereas self-management was not explained by sociodemographic or clinical variables, suggesting the influence of behavioral and psychosocial factors.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"671-678"},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Pro-inflammatory cytokines in response to systemic inflammatory response syndrome post extra-corporeal membrane oxygenator decannulation\".","authors":"","doi":"10.1177/03913988261492785","DOIUrl":"https://doi.org/10.1177/03913988261492785","url":null,"abstract":"","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"3913988261492785"},"PeriodicalIF":1.6,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and biomechanical investigation of a patient-specific total talar prosthesis for total talar replacement: A finite element analysis.","authors":"Md Qumar Tabrej, Amit Kumar, Jayanta Kumar Biswas","doi":"10.1177/03913988261486195","DOIUrl":"https://doi.org/10.1177/03913988261486195","url":null,"abstract":"<p><strong>Background: </strong>Total talar replacement (TTR) is an emerging treatment for end-stage talar diseases, although concerns persist regarding ankle stability due to essential ligament transection. Further investigation is necessary regarding the biomechanical impact of patient-specific total talar prosthesis (TTP) on ankle stability and bone-implant mechanics.</p><p><strong>Objective: </strong>The purpose of this study is designing a patient-specific TTP and assess its biomechanical performance on ankle stability and stress distribution under various loading conditions using finite element analysis.</p><p><strong>Methods: </strong>A CT scan is used to create a 3D finite element model of the foot and ankle complex. The TTP made of A dual-material (UHMWPE talar body and titanium alloy cage) was created and fixed with five screws. Four loading conditions were simulated: inversion, eversion, dorsiflexion, and plantarflexion, with forces of 10 N, 50 N, 100 N, and 150 N. Talar tilt angles and von Mises stresses were examined for intact and implanted models.</p><p><strong>Results: </strong>In comparison to the intact ankle, TTR significantly decreased the talar tilt angles in inversion (12.5%-16%), eversion (6.6%-14%), and dorsiflexion (33%-47%). On the other hand, plantarflexion produced a larger tilt (34%-44%). While bone stresses stayed below 5 MPa, maximum implant stresses ranged from 20 to 80 MPa. The validation of the model against cadaveric studies was reliable.</p><p><strong>Conclusion: </strong>The patient-specific TTP with screw fixation improves ankle stability in most loading directions, potentially compensating for ligament insufficiency. However, greater plantarflexion instability necessitates post-operative measures. These findings provide biomechanical evidence that fixation-enhanced TTP designs can improve therapeutic outcomes.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"3913988261486195"},"PeriodicalIF":1.6,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemodynamic effects of vena cava occlusion at different occlusion ratios and sites: A mock circulatory loop study.","authors":"Guangmao Liu, Jianqiang Hao, Zhaohui Zhang, Tianshuo Liu, Shengshou Hu","doi":"10.1177/03913988261487475","DOIUrl":"https://doi.org/10.1177/03913988261487475","url":null,"abstract":"<p><strong>Background: </strong>The haemodynamic effects of vena cava occlusion are related to the patient's preserved cardiac function. Investigating the haemodynamic effects is critical for the clinical translation of vena cava occlusion devices.</p><p><strong>Methods: </strong>A mock circulatory loop (MCL) system was developed for the in vitro haemodynamic simulation of the systemic venous system. Haemodynamic effects of vena cava occlusion were assessed under different heart failure states, different occlusion ratios and distinct occlusion sites.</p><p><strong>Results: </strong>Superior vena cava (SVC) occlusion significantly reduced both central venous pressure (CVP) and renal venous pressure (RVnP) while causing only a limited decrease in cardiac output (CO), however, jugular venous pressure (JVP) increased significantly. Inferior vena cava (IVC) occlusion below the right atrium caused negative CVP, a significant reduction in CO and increased RVnP. In contrast, IVC occlusion below the renal veins preserved CO while reducing RVnP and improving renal perfusion. Moreover, effective pressure gradients were observed at occlusion ratios of 82.3%-87.1% for SVC occlusion and IVC occlusion below the right atrium, compared with 94.5%-96.1% for IVC occlusion below the renal veins.</p><p><strong>Conclusion: </strong>SVC occlusion and IVC occlusion below the renal veins reduce cardiac preload and increase renal venous (RVn) flow, without significantly reducing CO. However, compared with SVC occlusion, IVC occlusion below the renal veins requires a higher occlusion ratio and provides limited ventricular unloading. IVC occlusion below the right atrium is not recommended, as this would lead to a significant reduction in CO and have adverse effects on the circulatory system.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"3913988261487475"},"PeriodicalIF":1.6,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the roles of anemia, renal impairment, and neuroinflammation in hemodialysis-associated cognitive dysfunction in chronic kidney disease patients.","authors":"Feifan Huang, Lingyun Wei, Meiying Huang, Yu Xiao, Ruiying Ma, Yanfei Nong, Jie Wang","doi":"10.1177/03913988261481049","DOIUrl":"https://doi.org/10.1177/03913988261481049","url":null,"abstract":"<p><strong>Background: </strong>The incidence of cognitive dysfunction (CD) is relatively high among patients with chronic kidney disease (CKD), and CD may be associated with anemia, deteriorating renal function, brain iron deposition (ID), and imbalances in neurocytokines. The purpose was to evaluate the changes in routine blood tests, renal function, cognitive function, brain ID, iron metabolism, and neurocytokines in patients with CKD-related CD.</p><p><strong>Methods: </strong>A retrospective analysis was conducted to compare differences in blood routine indicators, renal function indicators, Montreal Cognitive Assessment scale, brain iron deposition, iron metabolism indicators, and neurotrophic factors between hemodialysis patients with chronic kidney disease and cognitive impairment (observation group AG) and those without cognitive impairment (control group BG).</p><p><strong>Results: </strong>In contrast to the BG, the AG had significantly lower hemoglobin (Hb) levels; the AG had significantly higher creatinine (Cre) and uric acid (UA) levels, and a significantly lower estimated glomerular filtration rate (eGFR); the AG had significantly lower scores on the MoCA; the AG had significantly higher susceptibility values in the substantia nigra (SN), red nucleus (RN), globus pallidus (GP), and caudate nucleus (CN), and significantly lower susceptibility values in the putamen (PUT); the AG had significantly higher ferritin levels and significantly lower transferrin levels; the AG had significantly higher levels of neuron-specific enolase (NSE) and nerve growth factor (NGF), and significantly lower levels of brain-derived neurotrophic factor (BDNF; all <i>p</i> <i><</i> 0.05).</p><p><strong>Conclusion: </strong>Chronic kidney disease-related cognitive dysfunction results from the synergistic effects of multiple physiological systems, including anemia, renal failure, brain iron metabolism disorders, and neuroinflammation-neurotrophic imbalance. Hemodialysis patients not only exhibit significant anemia and reduced glomerular filtration function but also show abnormal iron deposition in specific brain regions, accompanied by notable alterations in iron metabolism indicators and neurotrophic factor profiles.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"3913988261481049"},"PeriodicalIF":1.6,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149060650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}