International Journal of Artificial Organs最新文献_第2页

Innovations in cardiac regenerative medicine: The role of tissue engineering. 心脏再生医学的创新：组织工程的作用。

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-09-01 Epub Date: 2025-09-05 DOI: 10.1177/03913988251370227

Rikuya Narabe, Yusuke Nishimura

引用次数: 0

Different anticoagulation methods for continuous renal replacement therapy in patients with hyperlactataemia and a high risk of bleeding. 不同抗凝方法对持续肾替代治疗高乳酸血症高危出血患者的影响。

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-09-01 Epub Date: 2025-08-16 DOI: 10.1177/03913988251360552

Chunyan Song, Rong Li, Siwei Tang, Siyan Tang, Peng Zhang, Ming Bai

{"title":"Different anticoagulation methods for continuous renal replacement therapy in patients with hyperlactataemia and a high risk of bleeding.","authors":"Chunyan Song, Rong Li, Siwei Tang, Siyan Tang, Peng Zhang, Ming Bai","doi":"10.1177/03913988251360552","DOIUrl":"10.1177/03913988251360552","url":null,"abstract":"Background: There is a lack of consensus regarding the optimal anticoagulation strategy for continuous renal replacement therapy (CRRT) in patients with hyperlactataemia and a high risk of bleeding. The purpose of this study was to evaluate the safety and efficacy of the commonly used anticoagulation methods for CRRT in these patients.Methods: The present study included patients with hyperlactataemia (⩾2 mmol/L) and a high risk of bleeding who underwent CRRT at Xijing Hospital from 2020 to 2024. Filter lifespan, bleeding complications, blood infusion and adverse effects were recorded.Results: The present study included a total of 53 patients who underwent no anticoagulation (NA)-CRRT, 32 patients who underwent nafamostat mesylate (NM)-CRRT and 47 patients who underwent regional citrate anticoagulation (RCA)-CRRT. The filter lifespan was significantly different among the three groups (NA = 25 h (IQR = 18.4, 34.5), NM = 41 h (IQR = 24.0, 54.3) and RCA = 36 h (IQR = 23.0, 53.5), p < 0.001). The 30-day mortality rate was significantly higher in the NA group (p = 0.037). Furthermore, the incidence of bleeding complications (43.4%, p = 0.003) and blood transfusions (28.3%, p = 0.047) were higher in the NA group.ConclusionThe utilization of either NM or RCA has the potential to extend the filter lifespan and may be associated with a reduced risk of bleeding. These findings suggest that NM and RCA may be safe and effective for CRRT patients with hyperlactataemia and a high risk of bleeding if careful monitoring and timely adjustment are employed.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"639-652"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges and implementation of extracorporeal membrane oxygenation transport program in a low-resource setting. 低资源环境下体外膜氧合运输计划的挑战和实施。

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-09-01 Epub Date: 2025-09-15 DOI: 10.1177/03913988251365130

Thao Thi Ngoc Pham, Xuan Thi Phan, Huy Minh Pham, Dai Quang Huynh, Quan Minh Quoc Du, Ngan Hoang Kim Trieu, Tuan Manh Nguyen, Yen Nguyen Hai Le, Duy Ba Nguyen, Anh Viet Ngo, Hung Qui Nguyen, Tuan Kha Nguyen, Toan Ngoc Le, Linh Thanh Tran

{"title":"Challenges and implementation of extracorporeal membrane oxygenation transport program in a low-resource setting.","authors":"Thao Thi Ngoc Pham, Xuan Thi Phan, Huy Minh Pham, Dai Quang Huynh, Quan Minh Quoc Du, Ngan Hoang Kim Trieu, Tuan Manh Nguyen, Yen Nguyen Hai Le, Duy Ba Nguyen, Anh Viet Ngo, Hung Qui Nguyen, Tuan Kha Nguyen, Toan Ngoc Le, Linh Thanh Tran","doi":"10.1177/03913988251365130","DOIUrl":"10.1177/03913988251365130","url":null,"abstract":"Background: Transporting patients on extracorporeal membrane oxygenation (ECMO) is a standard practice in high-resource settings but remains limited in low- and middle-income countries due to financial, infrastructural, and staffing constraints. This study evaluated the safety, complications, and outcomes of ECMO transport in a low-resource setting.Methods: This retrospective study conducted ECMO transport at a tertiary hospital in Ho Chi Minh City, Vietnam, from January 2019 to January 2023. Data on demographics, transport logistics, ECMO configuration, complications, and clinical outcomes were analyzed, including subgroup comparisons between COVID-19 and non-COVID-19 patients.Results: Thirty-nine patients (mean age 45 years; 56.4% female) underwent inter-hospital ECMO transport over a median distance of 7.9 km. All patients survived transport, although one patient (2.6%) had a mechanical complication. Other complications recorded during ECMO support included infection in 53.8%, major bleeding in 23.1%, and pneumothorax in 5.1%. Overall survival to discharge was 69.2%. COVID-19 patients had a significantly lower discharge survival than non-COVID-19 patients (42.9% vs. 81.8%, p = 0.029)Conclusion:ECMO transport can be safely implemented in low-resource settings, achieving outcomes comparable to in-house ECMO support. Further research is essential to develop standardized protocols and expand ECMO networks to improve patient outcomes in resource-limited settings.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"679-685"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145064650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical efficacy of acupoint massage combined with auricular points plaster therapy on sleep and quality of life in patients undergoing maintenance hemodialysis. 穴位按摩联合耳穴贴敷对维持性血液透析患者睡眠及生活质量的影响。

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-09-01 Epub Date: 2025-07-06 DOI: 10.1177/03913988251355087

Bihong Lai, Li Shen, Xiaocui Guo, Xia Shen, Lin Zhao, Shuiying Ye, Dongchi Zhou, Xiaowen Tang, Jindong Tong

{"title":"Clinical efficacy of acupoint massage combined with auricular points plaster therapy on sleep and quality of life in patients undergoing maintenance hemodialysis.","authors":"Bihong Lai, Li Shen, Xiaocui Guo, Xia Shen, Lin Zhao, Shuiying Ye, Dongchi Zhou, Xiaowen Tang, Jindong Tong","doi":"10.1177/03913988251355087","DOIUrl":"10.1177/03913988251355087","url":null,"abstract":"Objective: To explore the clinical efficacy of acupoint massage combined with auricular points plaster therapy on sleep quality and quality of life in patients undergoing Maintenance Hemodialysis (MHD).Methods: One hundred and twenty insomnia patients undergoing MHD from January 2022 to December 2024 were selected and randomly divided into an observation group (n = 60) and a control group (n = 60). The control group was given conventional treatment, while the observation group received acupoint massage combined with auricular points plaster therapy in addition to conventional treatment, with an intervention period of 4 weeks. After 4 weeks, the pre- and post-treatment Pittsburgh Sleep Quality Index (PSQI) and World Health Organization Quality of Life-BREF (WHOQOL-BREF) scores were compared, along with the Newcastle Nursing Satisfaction Scale (NSNS) scores between the two groups.Results: After 4 weeks of intervention, the observation group showed significant efficacy in TCM syndrome differentiation, with a response rate of 80.0%. The total PSQI and WHOQOL scores decreased (p < 0.05), with an overall response rate of 90.0%. Meanwhile, after 4 weeks of intervention, the observation group demonstrated significant efficacy in TCM syndrome differentiation after intervention for 4 weeks, with an overall response rate of 90.0%. Additionally, the PSQI score remarkably decreased (p < 0.05) and the WHOQOL-BREF score substantially increased (p < 0.05), with the NSNS score being markedly higher than that of the control group (p < 0.05).Conclusion: The selection of acupoints for acupoint massage combined with auricular points plaster therapy can improve sleep quality, quality of life, and nursing satisfaction in patients undergoing MHD.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"672-678"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of exposure below various thresholds of hemodynamic parameters during cardiopulmonary bypass with acute kidney injury. 体外循环期间血液动力学参数低于不同阈值暴露与急性肾损伤的关系。

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-08-25 DOI: 10.1177/03913988251365814

Takumi Sasaki, Toshiyuki Nakanishi, Tatsuya Tsuji, Eisuke Kako, Tetsuya Tamura, Koichi Fujiwara, Miho Murashima, Takayuki Hamano, Kazuya Sobue

{"title":"Association of exposure below various thresholds of hemodynamic parameters during cardiopulmonary bypass with acute kidney injury.","authors":"Takumi Sasaki, Toshiyuki Nakanishi, Tatsuya Tsuji, Eisuke Kako, Tetsuya Tamura, Koichi Fujiwara, Miho Murashima, Takayuki Hamano, Kazuya Sobue","doi":"10.1177/03913988251365814","DOIUrl":"https://doi.org/10.1177/03913988251365814","url":null,"abstract":"Introduction: This study aimed to investigate the association of exposure below various thresholds of mean arterial pressure (MAP), pump flow rates, and hemoglobin levels during cardiopulmonary bypass (CPB) with cardiac surgery-associated acute kidney injury (CSA-AKI).Methods: Adult patients undergoing cardiac surgery with CPB at a university hospital between April 2015 and August 2023 were included. The primary outcome was CSA-AKI within 7 days postoperatively. The primary exposures were the area under the threshold (AUT) of MAP, pump flow rate, and Hb during CPB. A multivariable logistic regression using covariates selected via Lasso regularization estimated the adjusted odds ratios (aORs) and 95% confidence intervals (CIs).Results: We finally analyzed 333 patients, of which 156 patients (46.8%) developed CSA-AKI. The AUT of hemoglobin, but not those of MAP and pump flow rate, was associated with CSA-AKI. The lower the threshold, the stronger the association (<8 g/dL, aOR = 1.132 per 10 g/dL × min, 95% CI = 1.036-1.243, p = 0.007; <9 g/dL, aOR = 1.048, 95% CI = 1.013-1.086, p = 0.007; and <10 g/dL, aOR = 1.027, 95% CI = 1.007-1.048, p = 0.010).Conclusion: Hemoglobin levels during CPB below 8.0 g/dL were associated with CSA-AKI, while MAP and pump flow rates indicated no such association.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"3913988251365814"},"PeriodicalIF":1.3,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of dengue myocarditis with impending cardiac arrest in a patient with double valve replacement using VA ECMO-case report. 双瓣膜置换术治疗登革性心肌炎并发心脏骤停1例

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-08-25 DOI: 10.1177/03913988251365845

Vipul Bansal, Vivek Gupta, Naved Aslam, Harneet Singh Khurana, Suvir Grover, Vikram Pal Singh, Gurpreet Singh Wander

{"title":"Management of dengue myocarditis with impending cardiac arrest in a patient with double valve replacement using VA ECMO-case report.","authors":"Vipul Bansal, Vivek Gupta, Naved Aslam, Harneet Singh Khurana, Suvir Grover, Vikram Pal Singh, Gurpreet Singh Wander","doi":"10.1177/03913988251365845","DOIUrl":"https://doi.org/10.1177/03913988251365845","url":null,"abstract":"Forty five years morbidly obese male with prosthetic mitral and aortic valve referred to our hospital with dengue shock syndrome. He had recurrent ventricular arrhythmias required multiple shock and short cycle of cardiopulmonary resuscitation (CPR). He was supported with high dose vasopressors and mechanical ventilation. Two-dimensional Echocardiography showed severe left ventricular (LV) dysfunction with left ventricular ejection fraction (LVEF) 8%-10% and mild increase in the gradient across aortic and mitral valve however there was no para-valvular leak or vegetations. Venoarterial (VA) extracorporeal membrane oxygenation (ECMO) was initiated along with continuous renal replacement therapy (CRRT) using Oxiris® filter in view of persistent ventricular arrhythmia, acute kidney injury (AKI) Grade 3 and severe acute hepatic dysfunction. The major concerns were severe myocardial dysfunction and malignant arrhythmias with impending cardiac arrest warranting the need for VA ECMO support while prosthetic valves especially aortic, uncertainty regarding myocardial dysfunction whether pre-existing or dengue induced and severe dysfunction of other organs were challenges for decision to initiate ECMO. This case describes successful ECMO management and challenges due to prosthetic valve as well as pre-existing severe myocardial dysfunction and concurrent other organ dysfunction.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"3913988251365845"},"PeriodicalIF":1.3,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skin-texture drug triggers: Can 2025's tactile medications enhance psychiatric treatment adherence? 皮肤纹理药物触发：2025的触觉药物能提高精神病治疗的依从性吗？

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-08-16 DOI: 10.1177/03913988251365566

Muhammad Talha, Maliha Khalid, Tejiri Napoleon

引用次数: 0

Enhanced hyper tuning using bioinspired-based deep learning model for accurate lung cancer detection and classification. 使用基于生物启发的深度学习模型增强超调谐，用于准确的肺癌检测和分类。

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-08-09 DOI: 10.1177/03913988251359522

Jyoti Kumari, Sapna Sinha, Laxman Singh

{"title":"Enhanced hyper tuning using bioinspired-based deep learning model for accurate lung cancer detection and classification.","authors":"Jyoti Kumari, Sapna Sinha, Laxman Singh","doi":"10.1177/03913988251359522","DOIUrl":"10.1177/03913988251359522","url":null,"abstract":"Lung cancer (LC) is one of the leading causes of cancer related deaths worldwide and early recognition is critical for enhancing patient outcomes. However, existing LC detection techniques face challenges such as high computational demands, complex data integration, scalability limitations, and difficulties in achieving rigorous clinical validation. This research proposes an Enhanced Hyper Tuning Deep Learning (EHTDL) model utilizing bioinspired algorithms to overcome these limitations and improve accuracy and efficiency of LC detection and classification. The methodology begins with the Smooth Edge Enhancement (SEE) technique for preprocessing CT images, followed by feature extraction using GLCM-based Texture Analysis. To refine the features and reduce dimensionality, a Hybrid Feature Selection approach combining Grey Wolf optimization (GWO) and Differential Evolution (DE) is employed. Precise lung segmentation is performed using Mask R-CNN to ensure accurate delineation of lung regions. A Deep Fractal Edge Classifier (DFEC) is introduced, consisting of five fractal blocks with convolutional layers and pooling to progressively learn LC characteristics. The proposed EHTDL model achieves remarkable performance metrics, including 99% accuracy, 100% precision, 98% recall, and 99% F1-score, demonstrating its robustness and effectiveness. The model's scalability and efficiency make it suitable for real-time clinical application offering a promising solution for early LC detection and significantly enhancing patient care.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"3913988251359522"},"PeriodicalIF":1.3,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organ-on-chip models for reconstructive tissue engineering: An evolutionary plastic surgery advance. 用于重建组织工程的器官芯片模型：整形外科的进化进展。

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-08-01 Epub Date: 2025-07-06 DOI: 10.1177/03913988251355075

Muhammad Talha, Maliha Khalid

引用次数: 0

Reoperation for the implantation of Corheart 6 biventricular assist devices due to severe right ventricular failure and aortic regurgitation following left ventricular assist device implantation. 由于左心室辅助装置植入后出现严重的右心室衰竭和主动脉反流，再次手术植入Corheart 6双心室辅助装置。

IF 1.3 4区医学

International Journal of Artificial Organs Pub Date : 2025-08-01 Epub Date: 2025-07-23 DOI: 10.1177/03913988251351122

Yafeng Liu, Li Yin, Yiming Liu, Liqiong Xiao, Hongwei Shi, Xiaochun Song, Zhibing Qiu, Xin Chen

{"title":"Reoperation for the implantation of Corheart 6 biventricular assist devices due to severe right ventricular failure and aortic regurgitation following left ventricular assist device implantation.","authors":"Yafeng Liu, Li Yin, Yiming Liu, Liqiong Xiao, Hongwei Shi, Xiaochun Song, Zhibing Qiu, Xin Chen","doi":"10.1177/03913988251351122","DOIUrl":"10.1177/03913988251351122","url":null,"abstract":"Background: We present the case of a 68-year-old patient who underwent secondary thoracotomy, implantation of a continuous-flow ventricular assist device (VAD) in a biventricular configuration, and aortic valve replacement (AVR) 2 years after receiving a continuous-flow left ventricular assist device (LVAD) and coronary artery bypass grafting (CABG), due to right ventricular failure, moderate aortic insufficiency, and damage to the original LVAD device cable.Case report: The patient initially received a Corheart 6 LVAD, CABG, and tricuspid annuloplasty due to end-stage heart failure resulting from ischemic cardiomyopathy and severe tricuspid regurgitation. Following the surgery, the patient was discharged with favorable outcomes. However, 2 years later, the patient was readmitted with severe right heart failure. Given the current shortage of heart donors, the decision was made to implant a Corheart 6 biventricular VAD (BiVAD) as destination therapy.Conclusion: Severe right ventricular failure is a well-recognized complication following continuous-flow LVAD implantation. In this case, it was successfully managed with BiVADs as destination therapy for this high-risk patient.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"575-580"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0