International Journal of Artificial Organs最新文献

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Fatigue by the Chalder Questionnaire and post-hemodialysis recovery in a population of predominantly African descent: The PROHEMO. 通过 Chalder 问卷了解非洲裔人群的疲劳情况和血液透析后的恢复情况:PROHEMO.
IF 1.4 4区 医学
International Journal of Artificial Organs Pub Date : 2024-06-01 DOI: 10.1177/03913988241255501
Gabriel Brayan Gutiérrez-Peredo, Márcia Tereza Silva Martins, Fernanda Albuquerque da Silva, Marcelo Barreto Lopes, Gildete Barreto Lopes, Sherman A James, Keith C Norris, Antonio Alberto Lopes
{"title":"Fatigue by the Chalder Questionnaire and post-hemodialysis recovery in a population of predominantly African descent: The PROHEMO.","authors":"Gabriel Brayan Gutiérrez-Peredo, Márcia Tereza Silva Martins, Fernanda Albuquerque da Silva, Marcelo Barreto Lopes, Gildete Barreto Lopes, Sherman A James, Keith C Norris, Antonio Alberto Lopes","doi":"10.1177/03913988241255501","DOIUrl":"https://doi.org/10.1177/03913988241255501","url":null,"abstract":"<p><strong>Background/objective: </strong>A high prevalence of fatigue and a positive association between fatigue and post-hemodialysis recovery have been reported in predominantly white populations of maintenance hemodialysis (MHD) patients. The present study evaluates associations between self-reported fatigue by the 11-item Chalder Fatigue Questionnaire (CFQ-11) and the need for post-hemodialysis recovery in a predominantly African-descent MHD population.</p><p><strong>Methods: </strong>A total of 233 patients (94% Black or Mixed-Race) participating in the \"Prospective Study of the Prognosis of Patients on Maintenance Hemodialysis\" (PROHEMO), Salvador, Brazil were recruited for this cross-sectional study. The CFQ-11 was used to measure fatigue: <4 for absent or mild, ⩾4 for moderate to severe. Patients were also asked if they needed some time to recover after the hemodialysis. Logistic regression was used to estimate odds ratio (OR) of the association with adjustments for age, sex, race, educational level, economic class level, diabetes, hearth failure, and hemoglobin.</p><p><strong>Results: </strong>Mean age was 51.5 ± 12.5 years. Moderate to severe fatigue (⩾4 points) was observed in 70.8% (165/233), and absent or mild fatigue (<4 points) in 29.2% (68/233). Compared to patients with fatigue scores <4 (20.6%), the need for post-hemodialysis recovery was 2.5 times greater in patients with fatigue scores ⩾4 (52.7%). The covariate-adjusted logistic regression OR was 4.60, 95% CI: 2.27, 9.21.</p><p><strong>Conclusion: </strong>This study in MHD patients of predominantly African descent supports self-reported fatigue assessed by the CFQ-11 as a relevant predictor of the need for post-hemodialysis recovery. The results offer a rationale for investigating whether interventions to prevent fatigue reduce the need of post-hemodialysis recovery.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":"47 6","pages":"373-379"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left ventricular unloading via percutaneous assist device during extracorporeal membrane oxygenation in acute myocardial infarction and cardiac arrest. 急性心肌梗死和心脏骤停患者在体外膜肺氧合过程中通过经皮辅助装置进行左心室卸载。
IF 1.4 4区 医学
International Journal of Artificial Organs Pub Date : 2024-06-01 Epub Date: 2024-06-10 DOI: 10.1177/03913988241254978
Jake M Kieserman, Ivan A Kuznetsov, Joseph Park, James W Schurr, Omar Toubat, Salim Olia, Christian Bermudez, Marisa Cevasco, Joyce Wald
{"title":"Left ventricular unloading via percutaneous assist device during extracorporeal membrane oxygenation in acute myocardial infarction and cardiac arrest.","authors":"Jake M Kieserman, Ivan A Kuznetsov, Joseph Park, James W Schurr, Omar Toubat, Salim Olia, Christian Bermudez, Marisa Cevasco, Joyce Wald","doi":"10.1177/03913988241254978","DOIUrl":"10.1177/03913988241254978","url":null,"abstract":"<p><strong>Introduction: </strong>A feared complication of an acute myocardial infarction (AMI) is cardiac arrest (CA). Even if return of spontaneous circulation is achieved, cardiogenic shock (CS) is common. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) supports patients with CS and is often used in conjunction with an Impella device (2.5 and CP) to off-load the left ventricle, although limited evidence supports this approach.</p><p><strong>Methods: </strong>The goal of this study was to determine whether a mortality difference was observed in VA-ECMO alone versus VA-ECMO with Impella (ECPELLA) in patients with CS from AMI and CA. A retrospective chart review of 50 patients with AMI-CS and CA and were supported with VA-ECMO (<i>n</i> = 34) or ECPELLA (<i>n</i> = 16) was performed. The primary outcome was all-cause mortality at 6-months from VA-ECMO or Impella implantation. Secondary outcomes included in-hospital mortality and complication rates between both cohorts and intensive care unit data.</p><p><strong>Results: </strong>Baseline characteristics were similar, except patients with ST-elevation myocardial infarction were more likely to be in the VA-ECMO group (<i>p</i> = 0.044). The ECPELLA cohort had significantly worse survival after VA-ECMO (SAVE) score (<i>p</i> = 0.032). Six-month all-cause mortality was not significantly different between the cohorts, even when adjusting for SAVE score. Secondary outcomes were notable for an increased rate of minor complications without an increased rate of major complications in the ECPELLA group.</p><p><strong>Conclusions: </strong>Randomized trials are needed to determine if a mortality difference exists between VA-ECMO and ECPELLA platforms in patients with AMI complicated by CA and CS.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"401-410"},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11826357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A chronic intermittent haemodialysis pig model for functional evaluation of dialysis membranes. 用于透析膜功能评估的慢性间歇性血液透析猪模型。
IF 1.7 4区 医学
International Journal of Artificial Organs Pub Date : 2024-05-01 Epub Date: 2024-05-13 DOI: 10.1177/03913988241253152
Shushi Yamamoto, Hiroshi Umeno, Yusuke Sano, Masahide Koremoto, Yoshimichi Goda, Yasuyuki Kaneko, Shidow Torisu, Toshihiro Tsuruda, Shouichi Fujimoto
{"title":"A chronic intermittent haemodialysis pig model for functional evaluation of dialysis membranes.","authors":"Shushi Yamamoto, Hiroshi Umeno, Yusuke Sano, Masahide Koremoto, Yoshimichi Goda, Yasuyuki Kaneko, Shidow Torisu, Toshihiro Tsuruda, Shouichi Fujimoto","doi":"10.1177/03913988241253152","DOIUrl":"10.1177/03913988241253152","url":null,"abstract":"<p><p>Performance evaluation of new dialysis membranes is primarily performed in vitro, which can lead to differences in clinical results. Currently, data on dialysis membrane performance and safety are available only for haemodialysis patients. Herein, we aimed to establish an in vivo animal model of dialysis that could be extrapolated to humans. We created a bilateral nephrectomy pig model of renal failure, which placed a double-lumen catheter with the hub exposed dorsally. Haemodialysis was performed in the same manner as in humans, during which clinically relevant physiologic data were evaluated. Next, to evaluate the utility of this model, the biocompatibility of two kinds of membranes coated with or without vitamin E used in haemodiafiltration therapy were compared. Haemodialysis treatment was successfully performed in nephrectomized pigs under the same dialysis conditions (4 h per session, every other day, for 2 weeks). In accordance with human clinical data, regular dialysis alleviated renal failure in pigs. The vitamin E-coated membrane showed a significant reduction rate of advanced oxidation protein products during dialysis than non-coated membrane. In conclusion, this model mimics the pathophysiology and dialysis condition of patients undergoing haemodialysis. This dialysis treatment model of renal failure will be useful for evaluating the performance and safety of dialysis membranes.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"321-328"},"PeriodicalIF":1.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial fibrillation increases thrombogenicity of LVAD therapy. 心房颤动会增加 LVAD 治疗的血栓形成。
IF 1.7 4区 医学
International Journal of Artificial Organs Pub Date : 2024-05-01 Epub Date: 2024-05-14 DOI: 10.1177/03913988241251706
Venkat Keshav Chivukula, Jennifer Beckman, Song Li, Nazem Akoum, Alberto Aliseda, Claudius Mahr
{"title":"Atrial fibrillation increases thrombogenicity of LVAD therapy.","authors":"Venkat Keshav Chivukula, Jennifer Beckman, Song Li, Nazem Akoum, Alberto Aliseda, Claudius Mahr","doi":"10.1177/03913988241251706","DOIUrl":"10.1177/03913988241251706","url":null,"abstract":"<p><strong>Background: </strong>This study investigates the hypothesis that presence of atrial fibrillation (AF) in LVAD patients increases thrombogenicity in the left ventricle (LV) and exacerbates stroke risk.</p><p><strong>Methods: </strong>Using an anatomical LV model implanted with an LVAD inflow cannula, we analyze thrombogenic risk and blood flow patterns in either AF or sinus rhythm (SR) using unsteady computational fluid dynamics (CFD). To analyze platelet activation and thrombogenesis in the LV, hundreds of thousands of platelets are individually tracked to quantify platelet residence time (RT) and shear stress accumulation history (SH).</p><p><strong>Results: </strong>The irregular and chaotic mitral inflow associated with AF results in markedly different intraventricular flow patterns, with profoundly negative impact on blood flow-induced stimuli experienced by platelets as they traverse the LV. Twice as many platelets accumulated very high SH in the LVAD + AF case, resulting in a 36% increase in thrombogenic potential score, relative to the LVAD + SR case.</p><p><strong>Conclusions: </strong>This supports the hypothesis that AF results in unfavorable blood flow patterns in the LV adding to an increased stroke risk for LVAD + AF patients. Quantification of thrombogenic risk associated with AF for LVAD patients may help guide clinical decision-making on interventions to mitigate the increased risk of thromboembolic events.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"329-337"},"PeriodicalIF":1.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140922181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel tubing connectors reduce ECMO circuit thrombosis. 新型管道连接器可减少 ECMO 电路血栓形成。
IF 1.7 4区 医学
International Journal of Artificial Organs Pub Date : 2024-05-01 Epub Date: 2024-05-14 DOI: 10.1177/03913988241252255
Christopher A Bresette, Susan M Shea, Scott Wagoner, Saagar Bakshi, Shriprasad R Deshpande, Kevin O Maher, David N Ku
{"title":"Novel tubing connectors reduce ECMO circuit thrombosis.","authors":"Christopher A Bresette, Susan M Shea, Scott Wagoner, Saagar Bakshi, Shriprasad R Deshpande, Kevin O Maher, David N Ku","doi":"10.1177/03913988241252255","DOIUrl":"10.1177/03913988241252255","url":null,"abstract":"<p><strong>Background: </strong>Thrombosis within extracorporeal membrane oxygenation (ECMO) circuits is a common complication that dominates clinical management of patients receiving mechanical circulatory support. Prior studies have identified that over 80% of circuit thrombosis can be attributed to tubing-connector junctions.</p><p><strong>Methods: </strong>A novel connector was designed that reduces local regions of flow stagnation at the tubing-connector junction to eliminate a primary source of ECMO circuit thrombi. To compare clotting between the novel connectors and the traditional connectors, both in vitro loops and an in vivo caprine model of long-term (48 h) ECMO were used to generate tubing-connector junction clots.</p><p><strong>Results: </strong>In vitro, the traditional connectors uniformly (9/9) formed large thrombi, while novel connectors formed a small thrombus in only one of nine (<i>p</i> < 0.0001). In the long-term goat ECMO circuits, the traditional connectors exhibited more thrombi (<i>p</i> < 0.04), and these thrombi were more likely to protrude into the lumen of the tubing (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Both in vitro and in vivo validation experiments successfully recreated circuit thrombosis and demonstrate that the adoption of novel connectors can reduce the burden of circuit thrombosis.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"347-355"},"PeriodicalIF":1.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140922097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does native vitamin D, or active vitamin D modulate the neutralising antibody responses to COVID-19 vaccination in haemodialysis patients? 原生维生素 D 或活性维生素 D 是否会调节血液透析患者接种 COVID-19 疫苗后的中和抗体反应?
IF 1.4 4区 医学
International Journal of Artificial Organs Pub Date : 2024-04-01 DOI: 10.1177/03913988241241204
Andrew Davenport
{"title":"Does native vitamin D, or active vitamin D modulate the neutralising antibody responses to COVID-19 vaccination in haemodialysis patients?","authors":"Andrew Davenport","doi":"10.1177/03913988241241204","DOIUrl":"10.1177/03913988241241204","url":null,"abstract":"<p><strong>Introduction: </strong>Several studies have reported that patients with low levels of Vitamin D<sub>3</sub> have impaired responses to vaccination, including COVID-19 vaccines, so we reviewed the response to COVID-19 vaccination in haemodialysis patients, who typically have reduced Vitamin D<sub>3</sub> levels.</p><p><strong>Methods: </strong>The inhibitory antibody (IC50) responses to several COVID-19 variants following vaccination in a cohort of United Kingdom haemodialysis patients receiving two vaccinations between March 2021 and May 2021 were reviewed.</p><p><strong>Results: </strong>A total of 183 haemodialysis patients, 65.5% male, mean age 65.6 ± 14.1 years, 46.4% diabetic, 42.1% white ethnicity, body mass index 26.9 ± 6.5 kg/m<sup>2</sup> dialysis vintage 36.2 (18.3-69.3) months were studied. Following the first vaccination, the median IgG microneutralisation IC50 response was undetectable for all variants (wild-type, alpha, beta and delta). Follow-up after the second vaccination showed that the microneutralisation response to all variants increased and was greater for the wild-type variant compared to alpha, beta and delta, all <i>p</i> < 0.001, There were no differences comparing the IC50 responses according to 25-Vitamin D<sub>3</sub> levels, and the prescription of activated Vitamin D. Although patients who had previously tested positive for COVID-19 prescribed higher doses of alfacalcidol had higher seroprotection responses to the alpha (χ<sup>2</sup> = 15, <i>p</i> = 0.002) and beta variants. (χ<sup>2</sup> = 13, <i>p</i> = 0.005).</p><p><strong>Conclusions: </strong>The response to COVID-19 vaccination was reduced in our elderly haemodialysis patients compared to younger less frail patients, however there was no overall demonstrable effect of either 25-Vitamin D<sub>3</sub> levels or the prescription of activated forms of Vitamin D on the immune response following vaccination against COVID-19, unless patients had previously tested positive for COVID-19.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"251-259"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140335535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between a low-risk COVID-19 extracorporeal membrane oxygenation criteria and mortality: A retrospective study. 低风险 COVID-19 体外膜肺氧合标准与死亡率之间的关系:一项回顾性研究。
IF 1.7 4区 医学
International Journal of Artificial Organs Pub Date : 2024-04-01 Epub Date: 2024-03-20 DOI: 10.1177/03913988241239198
Igor Gostyuzhev, Adham Mohamed, Carole E Freiberger-O'Keefe, Michelle M Haines, Jonathan B Kozinn
{"title":"Association between a low-risk COVID-19 extracorporeal membrane oxygenation criteria and mortality: A retrospective study.","authors":"Igor Gostyuzhev, Adham Mohamed, Carole E Freiberger-O'Keefe, Michelle M Haines, Jonathan B Kozinn","doi":"10.1177/03913988241239198","DOIUrl":"10.1177/03913988241239198","url":null,"abstract":"<p><strong>Objective: </strong>Our study aimed to compare the outcomes of COVID-19 patients who met a low-risk inclusion criteria for veno-venous extra corporeal membrane oxygenation (VV ECMO) with those who did not meet criteria due to higher risk but were subsequently cannulated.</p><p><strong>Methods: </strong>This was a retrospective observational cohort study that included adult patients who were placed on VV ECMO for COVID-19 related acute respiratory distress syndrome (ARDS) at a tertiary care academic medical center. The primary outcome was the association between the low-risk criteria and mortality. The patients met the criteria if they met EOLIA severe ARDS criteria, no absolute contraindications (age > 60 years, BMI > 55 kg/m<sup>2</sup>, mechanical ventilation (MV) duration >7 days, irreversible neurologic damage, chronic lung disease, active malignancy, or advanced multiorgan dysfunction), and had three or less relative contraindications (age > 50 years, BMI > 45 kg/m<sup>2</sup>, comorbidities, MV duration > 4 days, acute kidney injury, receiving vasopressors, hospital LOS > 14 days, or COVID-19 diagnosis > 4 weeks).</p><p><strong>Results: </strong>Sixty-five patients were included from March 2020 through March 2022. Patients were stratified into low-risk or high-risk categories. The median Sequential Organ Failure Assessment score was 7 and the median PaO2/FiO2 ratio was 44 at the time of ECMO cannulation. The in-hospital mortality was 47.8% in the low-risk group and 69.0% in the high-risk group (<i>p</i> = 0.096).</p><p><strong>Conclusion: </strong>There was not a statistically significant difference in survival between low-risk patients and high-risk patients; however, there was a trend toward higher survival in the lower-risk group.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"309-312"},"PeriodicalIF":1.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140174554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
External validation of the PC-ECMO score in postcardiotomy veno-arterial extracorporeal membrane oxygenation. 心肌梗死术后静脉-动脉体外膜肺氧合PC-ECMO评分的外部验证。
IF 1.7 4区 医学
International Journal of Artificial Organs Pub Date : 2024-04-01 Epub Date: 2024-03-10 DOI: 10.1177/03913988241237701
Fausto Biancari, Tatu Juvonen, Sung-Min Cho, Francisco J Hernández Pérez, Camilla L'Acqua, Amr A Arafat, Mohammed M AlBarak, Mohamed Laimoud, Ilija Djordjevic, Robertas Samalavicius, Marta Alonso-Fernandez-Gatta, Sebastian D Sahli, Alexander Kaserer, Carmelo Dominici, Timo Mäkikallio
{"title":"External validation of the PC-ECMO score in postcardiotomy veno-arterial extracorporeal membrane oxygenation.","authors":"Fausto Biancari, Tatu Juvonen, Sung-Min Cho, Francisco J Hernández Pérez, Camilla L'Acqua, Amr A Arafat, Mohammed M AlBarak, Mohamed Laimoud, Ilija Djordjevic, Robertas Samalavicius, Marta Alonso-Fernandez-Gatta, Sebastian D Sahli, Alexander Kaserer, Carmelo Dominici, Timo Mäkikallio","doi":"10.1177/03913988241237701","DOIUrl":"10.1177/03913988241237701","url":null,"abstract":"<p><p>Reliable stratification of the risk of early mortality after postcardiotomy veno-arterial extracorporeal membrane oxygenation (V-A-ECMO) remains elusive. In this study, we externally validated the PC-ECMO score, a specific risk scoring method for prediction of in-hospital mortality after postcardiotomy V-A-ECMO. Overall, 614 patients who required V-A-ECMO after adult cardiac surgery were gathered from an individual patient data meta-analysis of nine studies on this topic. The AUC of the logistic PC-ECMO score in predicting in-hospital mortality was 0.678 (95%CI 0.630-0.726; <i>p</i> < 0.0001). The AUC of the logistic PC-ECMO score in predicting on V-A-ECMO mortality was 0.652 (95%CI 0.609-0.695; <i>p</i> < 0.0001). The Brier score of the logistic PC-ECMO score for in-hospital mortality was 0.193, the slope 0.909, the calibration-in-the-large 0.074 and the expected/observed mortality ratio 0.979. 95%CIs of the calibration belt of fit relationship between observed and predicted in-hospital mortality were never above or below the bisector (<i>p</i> = 0.072). The present findings suggest that the PC-ECMO score may be a valuable tool in clinical research for stratification of the risk of patients requiring postcardiotomy V-A-ECMO.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"313-317"},"PeriodicalIF":1.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Closed reduction of dislocated hip prosthesis using a traction table. 使用牵引台对脱位的髋关节假体进行闭合复位。
IF 1.7 4区 医学
International Journal of Artificial Organs Pub Date : 2024-04-01 Epub Date: 2024-03-22 DOI: 10.1177/03913988241234221
Tomonori Shigemura, Yohei Yamamoto, Yasuaki Murata
{"title":"Closed reduction of dislocated hip prosthesis using a traction table.","authors":"Tomonori Shigemura, Yohei Yamamoto, Yasuaki Murata","doi":"10.1177/03913988241234221","DOIUrl":"10.1177/03913988241234221","url":null,"abstract":"<p><p>This article describes three cases in which a dislocated hip prosthesis was reduced by a new reduction technique - that we previously described - using traction table. The dissociation of a prosthesis is a rare but serious complication of closed reduction manoeuvre. The new reduction manoeuvre using a traction table may be a good option to avoid dissociation of the prosthesis during closed reduction for treatment of dislocation after total hip arthroplasty.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"299-302"},"PeriodicalIF":1.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140184410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multi-constituent model for assessing the effect of impeller shroud on the thrombosis potential of a centrifugal blood pump. 用于评估叶轮护罩对离心血泵血栓形成可能性影响的多成分模型。
IF 1.7 4区 医学
International Journal of Artificial Organs Pub Date : 2024-04-01 Epub Date: 2024-03-20 DOI: 10.1177/03913988241239456
Shen Lv, Zhi-Peng He, Guang-Mao Liu, Sheng-Shou Hu
{"title":"A multi-constituent model for assessing the effect of impeller shroud on the thrombosis potential of a centrifugal blood pump.","authors":"Shen Lv, Zhi-Peng He, Guang-Mao Liu, Sheng-Shou Hu","doi":"10.1177/03913988241239456","DOIUrl":"10.1177/03913988241239456","url":null,"abstract":"<p><p>Centrifugal blood pumps can be used for treating heart failure patients. However, pump thrombosis has remained one of the complications that trouble clinical treatment. This study analyzed the effect of impeller shroud on the thrombosis risk of the blood pump, and predicted areas prone to thrombosis. Multi-constituent transport equations were presented, considering mechanical activation and biochemical activation. It was found that activated platelets concentration can increase with shear stress and adenosine diphosphate(ADP) concentration increasing, and the highest risk of thrombosis inside the blood pump was under extracorporeal membrane oxygenation (ECMO) mode. Under the same condition, ADP concentration and thrombosis index of semi-shroud impeller can increase by 7.3% and 7.2% compared to the closed-shroud impeller. The main reason for the increase in thrombosis risk was owing to elevated scalar shear stress and more coagulation promoting factor-ADP released. The regions with higher thrombosis potential were in the center hole, top and bottom clearance. As a novelty, the findings revealed that impeller shroud can influence mechanical and biochemical activation factors. It is useful for identifying potential risk regions of thrombus formation based on relative comparisons.</p>","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"269-279"},"PeriodicalIF":1.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140174553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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