International Journal of Artificial Organs最新文献_第10页

Sex-specific differences in a large cohort of Brazilian incident dialysis patients over 12 years: A retrospective study. 一项回顾性研究：12 年来巴西大量透析患者的性别差异：回顾性研究

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-01-24 DOI: 10.1177/03913988231225137

Fabiana Baggio Nerbass, Helbert do Nascimento Lima, Jocemir Ronaldo Lugon, Ricardo Sesso

{"title":"Sex-specific differences in a large cohort of Brazilian incident dialysis patients over 12 years: A retrospective study.","authors":"Fabiana Baggio Nerbass, Helbert do Nascimento Lima, Jocemir Ronaldo Lugon, Ricardo Sesso","doi":"10.1177/03913988231225137","DOIUrl":"10.1177/03913988231225137","url":null,"abstract":"Objective: Sex-specific differences in the epidemiology of chronic kidney disease, such as higher prevalence of women on pre-dialysis and men on chronic dialysis treatment, have been reported worldwide. In this regard, data from non-high-income countries are scarce. We aimed to compare the demographic, clinical, and dialysis characteristics of incident dialysis patients, both men and women, in a large cohort of Brazilian patients over a 12-year period.Methods: This was a multicentric retrospective cohort study coordinated by the Brazilian Society of Nephrology. The study included all adult incident dialysis patients in the Brazilian Dialysis Registry from January 2011 to December 2022. The variables studied encompassed age, skin color, education, CKD etiology, predialysis nephrologist care, dialysis characteristics, and geographic region. Additionally, the sample was analyzed for each of the three 4-year periods over the 12 years of data collection.Results: A total of 24,632 incident dialysis patients were included. Men were 59.1% of the dialysis population, remaining stable over the three 4-year periods. Besides other differences, women started dialysis younger (58.5 ± 16.2 years vs 59.5 ± 14.4 years; p < 0.001), had a lower educational level (less than 8 years at school: 54% vs 44%; p < 0.001), received more predialysis nephrologist care (46.2% vs 44.2%; p = 0.04), and had a higher prevalence of peritoneal dialysis (4.4% vs 3.5%; p = 0.03).Conclusion: We consistently observed a higher prevalence of men on dialysis and differences in demographic, clinical, and dialysis characteristics. The underlying reasons for these sex differences still necessitate further clarification.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"140-146"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139546312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimal timing of SARS-CoV-2 vaccination prior to cardiovascular surgery under cardiopulmonary bypass. 在心肺旁路下进行心血管手术前接种 SARS-CoV-2 疫苗的最佳时机。

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-02-28 DOI: 10.1177/03913988241234475

Ryosuke Hayashi, Yoshiyuki Takami, Hidetsugu Fujigaki, Kentaro Amano, Kiyotoshi Akita, Koji Yamana, Atsuo Maekawa, Kuniaki Saito, Yasushi Takagi

{"title":"Optimal timing of SARS-CoV-2 vaccination prior to cardiovascular surgery under cardiopulmonary bypass.","authors":"Ryosuke Hayashi, Yoshiyuki Takami, Hidetsugu Fujigaki, Kentaro Amano, Kiyotoshi Akita, Koji Yamana, Atsuo Maekawa, Kuniaki Saito, Yasushi Takagi","doi":"10.1177/03913988241234475","DOIUrl":"10.1177/03913988241234475","url":null,"abstract":"Background: mRNA vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became common. We investigated the optimal timing for inoculation against SARS-COV-2 in the candidates for cardiac surgery under cardiopulmonary bypass (CPB).Methods: In 100 patients with preoperative vaccination, who underwent CPB surgery between July 2021 and February 2022, the IgG against the receptor binding domain (RBD-IgG), with a threshold of >100 binding antibody unit (BAU)/mL for adequate immunity, was measured.Results: The vaccines, including 87 BNT162b2 (Pfizer/BioNTech) and 13 mRNA-1273 (Moderna), were inoculated at 98.8 ± 59.4 days before surgery. The median RBD-IgG titers before surgery, 1 day after surgery, and 1 month after surgery were 166.8, 100.0, and 84.0 BAU/mL, respectively. The standby interval (SBI) from the vaccination to the surgery showed a significantly negative correlations with the RBD-IgG titer before the surgery (p < 0.001). A cut-off SBI for RBD-IgG >100 BAU/mL before surgery was <81 days with a sensitivity of 76%, specificity of 62%, and area under ROC value of 0.73 (p = 0.03). The patients with SBI <81 days (n = 48) had significantly higher RBD-IgG (>100 BAU/mL) than those with SBI ⩾81 days (n = 52) at all perioperative periods.Conclusions: Although 40% of the RBD-IgG titers reduce 1 day after CPB surgery, the patients who received the SARS-COV-2 vaccination within an 81-day window prior to the surgery maintained a desirable RBD-IgG level, even up to 1 month after surgery. It may be important to schedule the surgery no later than 81 days after the vaccination.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"147-154"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139982928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microaxial mechanical circulatory support after orthotopic heart transplantation. 矫形心脏移植后的微轴机械循环支持。

IF 1.4 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-02-19 DOI: 10.1177/03913988231213722

Christopher Pritting, Danial Ahmad, Keyur Patel, Takuma Miyamoto, Taufiek K Rajab, Indranee N Rajapreyar, Howard T Massey, Vakhtang Tchantchaleishvili

{"title":"Microaxial mechanical circulatory support after orthotopic heart transplantation.","authors":"Christopher Pritting, Danial Ahmad, Keyur Patel, Takuma Miyamoto, Taufiek K Rajab, Indranee N Rajapreyar, Howard T Massey, Vakhtang Tchantchaleishvili","doi":"10.1177/03913988231213722","DOIUrl":"10.1177/03913988231213722","url":null,"abstract":"Aim: Use of microaxial mechanical circulatory support (MCS) has been reported for severe graft rejection or dysfunction after heart transplantation (HTx). We aimed to assess utilization patterns of microaxial MCS after HTx in adolescents (ages 18 and younger) and adults (ages 19 and older).Methods: Electronic search was performed to identify all relevant studies on post-HTx use of microaxial support in adults and adolescents. A total of 18 studies were selected and patient-level data were extracted for statistical analysis.Results: All patients (n=23), including adults (n=15) and adolescents (n=8), underwent Impella (Abiomed, Danvers, MA) microaxial MCS after HTx. Median age was 36 [IQR 18-56] years (Adults, 52 [37-59]; adolescents, 16 [15-17]). Primary right ventricular graft dysfunction was an indication exclusively seen in the adults 40% (6/15), while acute graft rejection was present in 46.7% (7/15) of adults. Median time after transplant was 9 [0-32] months (Adults, 4 [0-32]; adolescents, 11 [4.5, 45]). Duration of Impella support was comparable between adults and adolescents (5 [2.5-8] vs 6 [5-8] days, p = 0.38). Overall improvement was observed both in median LV ejection fraction (23.5% [11.3-28] to 42% [37.8-47.3], p < 0.01) and cardiac index (1.8 [1.2-2.6] to 3 [2.5-3.1], p < 0.01). Retransplantation was required in four adolescents (50%, 4/8). Survival to discharge was achieved by 60.0% (9/15) of adults and 87.5% (7/8) of adolescents respectively (p = 0.37).Conclusion: Indications for microaxial MCS appear to vary between adult and adolescent patients. Overall improvement in LVEF and cardiac index was observed, however, with suboptimal survival to discharge.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"173-180"},"PeriodicalIF":1.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of erythrocyte membrane oxidation due to their exposure to shear flow generated by extracorporeal blood pump. 评估红细胞膜因暴露于体外血液泵产生的剪切流而氧化的情况。

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-02-29 DOI: 10.1177/03913988241230942

Masataka Inoue, Yuki Udono, Yugo Kato, Koji Fukui, Nobuo Watanabe

{"title":"Evaluation of erythrocyte membrane oxidation due to their exposure to shear flow generated by extracorporeal blood pump.","authors":"Masataka Inoue, Yuki Udono, Yugo Kato, Koji Fukui, Nobuo Watanabe","doi":"10.1177/03913988241230942","DOIUrl":"10.1177/03913988241230942","url":null,"abstract":"Several similarities have been found between shear stress-induced erythrocyte damage and physiological aging of erythrocytes in terms of elevated mechanical fragility, increased erythrocyte aggregation, and decreased membrane surface charge. Accordingly, we hypothesized that blood pump circulation, which generates shear stress, would accelerate erythrocyte aging, manifesting as oxidation. Therefore, the purpose of this study was to investigate the effect of blood pump circulation on erythrocyte oxidation. Fresh porcine blood was acquired from a slaughterhouse and anticoagulated with sodium citrate. About 500 mL of anticoagulated whole blood was circulated for 180 min in an in vitro test circuit comprising a BP-80 blood pump with a pump speed and a pump pressure head of 100-120 mmHg. A blood sample was taken at the start of the circulation and 180 min afterward. The hemolysis level and oxidation amount of the erythrocyte membrane were analyzed and compared between samples. Hemolysis increased with the prolongation of shear exposure inside the pump circuit. After 180 min of blood pumping in circuit, the oxidation level of the erythrocyte membrane showed an increase of 0.1 nmol/mg protein. Moreover, the membrane oxidation levels of sheared erythrocytes were greater than those of control erythrocytes. These results suggest that blood pump circulation accelerates erythrocyte aging and give us a greater understanding of the effects of blood pump perfusion.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"155-161"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10938486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139996146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Candida auris during extracorporeal life support: A case report. 体外生命支持期间念珠菌的治疗：病例报告。

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-01-28 DOI: 10.1177/03913988231226357

Paul Dobry, Stephanie B Edwin, Tsz Hin Ng, Karey Dutcheshen, Amir Kaki, Theodore L Schreiber

引用次数: 0

Letter. 信。

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-02-05 DOI: 10.1177/03913988241228677

Liliana de Meira Lins Kassar, João Paulo Senna, Karoline Wayla, Luiza Karla Rp Araujo, Benedito J Pereira, Hugo Abensur, Rosilene M Elias

引用次数: 0

Platelet volume indices and von Willebrand factor levels in blood exposed to polymer- or heparin-coated membrane oxygenators. 暴露于聚合物或肝素涂层膜氧合器的血液中的血小板体积指数和 von Willebrand 因子水平。

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-02-07 DOI: 10.1177/03913988231223360

Masashi Tagaya, Shinya Okano, Takuo Murataka, Hiroki Handa, Shunsuke Ichikawa, Shunsuke Takahashi

{"title":"Platelet volume indices and von Willebrand factor levels in blood exposed to polymer- or heparin-coated membrane oxygenators.","authors":"Masashi Tagaya, Shinya Okano, Takuo Murataka, Hiroki Handa, Shunsuke Ichikawa, Shunsuke Takahashi","doi":"10.1177/03913988231223360","DOIUrl":"10.1177/03913988231223360","url":null,"abstract":"Introduction: To understand the behavior of platelet volume indices and the von Willebrand factor (VWF), in vitro experiments using whole human blood were performed with extracorporeal circulation (ECC) circuits, including membrane oxygenators coated with acrylate copolymer (ACP) or immobilized heparin (IHP).Methods: Heparinized blood was circulated through two distinct experimental circuits: an ACP-coated reservoir and tubes, as well as membranes coated with either ACP or IHP (comprising five pieces of each type). The platelet distribution width, mean platelet volume (MPV), platelet large cell ratio (P-LCR), VWF quantity (VWFQ), and VWF activity (VWFA) were measured at 0, 8, 16, 24, and 32 h in each experiment. A two-way analysis of variance (ANOVA) was performed to determine whether the coating type or circulation duration affected the transition of each measurement.Results: Two-way ANOVA indicated that the transitions of MPV, P-LCR, and VWFA were significantly affected by the circulation duration (p = 0.030, 0.001, and <0.001, respectively) and that the transitions of VWFQ and VWFA were significantly affected by the coating type (p = 0.022 and 0.006, respectively). Factor interactions between the coating type and circulation duration were not observed for each transition (p > 0.05).Conclusions: Our findings suggest that P-LCR is a good index for platelet activation in blood-circulating ECC and that VWFA and VWFQ are significantly attenuated in blood-circulating ECC with ACP-coated membranes, indicating the advantage of IHP coating regarding platelet activation.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"198-204"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139702478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomechanical analysis of cervical spine (C2-C7) at different flexed postures. 不同屈曲姿势下颈椎（C2-C7）的生物力学分析。

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-02-16 DOI: 10.1177/03913988241229625

Bhanu Priya Dandumahanti, Murali Subramaniyam

{"title":"Biomechanical analysis of cervical spine (C2-C7) at different flexed postures.","authors":"Bhanu Priya Dandumahanti, Murali Subramaniyam","doi":"10.1177/03913988241229625","DOIUrl":"10.1177/03913988241229625","url":null,"abstract":"Musculoskeletal diseases are often related with postural changes in the neck region that can be caused by prolonged cervical flexion. This is one of the contributing factors. When determining the prevalence, causes, and related risks of neck discomfort, having a solid understanding of the biomechanics of the cervical spine (C1-C7) is absolutely necessary. The objective of this study is to make predictions regarding the intervertebral disc (IVD) stress values across C2-C7 IVD, the ligament stress, and the variation at 0°, 15°, 30°, 45°, and 60° of cervical neck angle using finite element analysis (FEA). In order to evaluate the mechanical properties of the cervical spine (particularly, C2-C7), this investigation makes use of computed tomography (CT) scans to develop a three-dimensional FEA model of the cervical spine. A preload of 50 N compression force was applied at the apex of the C2 vertebra, and all degrees of freedom below the C7 level were constrained. The primary objective of this investigation is to assess the distribution of von Mises stress within the IVDs and ligaments spanning C2-C7 at various flexion angles: 0°, 15°, 30°, 45°, and 60°, utilizing FEA. The outcomes derived from this analysis were subsequently compared to previously published experimental and FEA data to validate the model's ability to replicate the physiological motion of the cervical spine across different flexion angles.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"205-211"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139740958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Step by step enhancement of aesthetics for distal phalangeal prosthetic replacement using neoteric stamp technique: A case report. 使用新印章技术逐步提高远端趾骨假体置换术的美学效果：病例报告。

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-02-21 DOI: 10.1177/03913988241232315

Komal Kaur Saroya, Vishal Kumar, Surbhi Sharma, Sonam Kalsi

引用次数: 0

Physiologic benefits of veno-pulmonary extracorporeal membrane oxygenation for COVID-19 ARDS: A single center experience. 静脉-肺体外膜氧合治疗 COVID-19 ARDS 的生理优势：单中心经验。

IF 1.7 4区医学

International Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2024-02-28 DOI: 10.1177/03913988241234543

John C Grotberg, Jon Greenberg, Mary Sullivan, Amit A Pawale, Kunal D Kotkar, Muhammad F Masood

{"title":"Physiologic benefits of veno-pulmonary extracorporeal membrane oxygenation for COVID-19 ARDS: A single center experience.","authors":"John C Grotberg, Jon Greenberg, Mary Sullivan, Amit A Pawale, Kunal D Kotkar, Muhammad F Masood","doi":"10.1177/03913988241234543","DOIUrl":"10.1177/03913988241234543","url":null,"abstract":"Background: A subset of patients with COVID-19 acute respiratory distress syndrome (ARDS) require extracorporeal membrane oxygenation (ECMO). Veno-pulmonary (VP) ECMO provides support to the right ventricle and decreased risk of recirculation.Methods: A retrospective analysis of patients with COVID-19 ARDS and VP ECMO was performed. Patients were separated into groups by indication (1) \"right ventricular (RV) failure,\" (2) \"refractory hypoxemia,\" and (3) \"recurrent suck-down events (SDEs).\" Pre- and post-configuration vasoactive inotropic scores (VIS), fraction of inspired oxygen (FIO2), and resolution of SDEs were reported. A 90-day mortality was computed for all groups. Patients were also compared to those who underwent conventional venovenous (VV) ECMO.Results: Forty-seven patients underwent VP ECMO configuration, 18 in group 1, 16 in group 2, and 8 in group 3. Ninety-day mortality was 66% for the entire cohort and was 77.8%, 81.3% and 37.5% for groups 1, 2, and 3, respectively. Mean VIS decreased in group 1 (8.3 vs 2.9, p = 0.005), while mean FIO2 decreased in the group 2 and was sustained at 72 h (82.5% vs 52.5% and 47.5%, p < 0.001). Six of the eight (75%) of patients with recurrent SDEs had resolution of these events after configuration to VP ECMO. Patients with VP ECMO spent more days on ECMO (33 days compared to 18 days, p = 0.004) with no difference in mortality (66% compared to 55.1%, p = 0.28).Conclusion: VP ECMO in COVID-19 ARDS improves hemodynamics in patients with RV failure, improves oxygenation in patients with refractory hypoxemia and improves the frequency of SDEs.","PeriodicalId":13932,"journal":{"name":"International Journal of Artificial Organs","volume":" ","pages":"181-189"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0