Fangqun Wang, Fan Xu, Fenglian Zhu, Shaojun Wang, Chenyang He, Litao Ding, Mengping Li
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引用次数: 0
摘要
双心室辅助装置(BiVAD)作为双心室心力衰竭患者的一种治疗方式,其主要挑战在于生理活动变化时全身血流的平衡和防止心室抽吸。本研究构建了双心室循环系统(BCS)模型,并提出了基于斯塔林样控制器和滑动模式控制器(SMC)的生理组合控制器。通过模拟肺动脉阻力升高和静息-运动两组生理状态变化实验,研究了生理控制器对 BCS 血液动力学的影响,控制器分别为恒速(CS)控制器和类 Starling 控制器与 PI 控制器组合(SL-PI)控制器。仿真和实验结果表明,类星凌和滑模控制(SL-SMC)生理组合控制器能有效防止心室抽吸的发生,提供更高的心输出量,维持全身血流平衡,并在生理状态变化时具有更高的响应速度和鲁棒性。
Performance study of dual heart assisted control system based on SL-SMC physiological combination controller.
The main challenges of Biventricular Assist Devices (BiVAD) as a treatment modality for patients with Bicardiac heart failure heart failure are the balance of systemic blood flow during changes in physiological activity and the prevention of ventricular suction. In this study, a model of the Biventricular Circulatory System (BCS) was constructed and a physiological combination controller based on Starling-Like controller and Sliding Mode Controller (SMC) was proposed. The effects of the physiological controller on the hemodynamics of the BCS were investigated by simulating two sets of physiological state change experiments: elevated pulmonary artery resistance and resting-exercise, with constant speed (CS) control and combined Starling-like and PI control (SL-PI) as controllers. Simulation and experimental results showed that the Starling-like and Sliding Mode Control (SL-SMC) physiological combination controller was effective in preventing the occurrence of ventricular suction, providing higher cardiac output, maintain balance of systemic blood flow, and have higher response speed and robustness in the face of physiological state changes.
期刊介绍:
The International Journal of Artificial Organs (IJAO) publishes peer-reviewed research and clinical, experimental and theoretical, contributions to the field of artificial, bioartificial and tissue-engineered organs. The mission of the IJAO is to foster the development and optimization of artificial, bioartificial and tissue-engineered organs, for implantation or use in procedures, to treat functional deficits of all human tissues and organs.