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International Journal of Pharmaceutical Chemistry and Analysis最新文献

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Fabrication of zero-valent iron nanoparticles by green and chemical reduction methods: Application in the field of antibacterial activities for medicinal point of view 绿色和化学还原法制备零价铁纳米颗粒:从抗菌活性角度探讨其在医药领域的应用
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-10-15 DOI: 10.18231/j.ijpca.2021.023
M. Srivastava, Preeti Tomer, Anamika Srivastava, Swapnil Sharma
{"title":"Fabrication of zero-valent iron nanoparticles by green and chemical reduction methods: Application in the field of antibacterial activities for medicinal point of view","authors":"M. Srivastava, Preeti Tomer, Anamika Srivastava, Swapnil Sharma","doi":"10.18231/j.ijpca.2021.023","DOIUrl":"https://doi.org/10.18231/j.ijpca.2021.023","url":null,"abstract":"In the area of life sciences,iron nanoparticles (Fe NPs) have many applications. In this paper, the unique properties of iron nanoparticles as antimicrobials are studied. In this study, nanoparticles of iron have been fabricated by green and chemical reduction method. With the help of FESEM analysis and Zeta size analysis, the usual value of nanoparticles was found to be 10-30 nm in size. Furthermore, the prepared nanoparticles were examined for antibacterial perspective aligned with gram-positive and negative strains namely Staphylococcus aureus & Bacillus subtilis and Escherichia coli, using agar plate method and IC was also estimated using tube dilution assay.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86959654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review on: Medicinal properties of ginkgo biloba 银杏叶药用特性研究进展
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-10-15 DOI: 10.18231/j.ijpca.2021.018
S. S. Shaikh, N. Dighe
{"title":"A review on: Medicinal properties of ginkgo biloba","authors":"S. S. Shaikh, N. Dighe","doi":"10.18231/j.ijpca.2021.018","DOIUrl":"https://doi.org/10.18231/j.ijpca.2021.018","url":null,"abstract":"Traditional medicine and medicinal plants, as well as their study of modern chemical principles, may lead to the development of newer, less expensive medications. Ginkgo Biloba is well-known for curing a variety of ailments and is utilized in a variety of traditional medicinal formulations. Scientists and researchers from all over the world have spent decades studying the chemical composition of the entire Ginkgo Biloba plant, as well as its biological and pharmacological functions. These investigations established Ginkgo Biloba's medicinal potential in modern medicine and as a prospective drug discovery candidate. The current paper provides an overview of Ginkgo Bilobaethnobotany, phytochemistry, pharmacology, and toxicity.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73732895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analytical tools in protein structure determination 蛋白质结构测定的分析工具
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-10-15 DOI: 10.18231/j.ijpca.2021.021
K. R. Gupta, Uttam Patle, U. Kabra, P. Mishra, M. Umekar
{"title":"Analytical tools in protein structure determination","authors":"K. R. Gupta, Uttam Patle, U. Kabra, P. Mishra, M. Umekar","doi":"10.18231/j.ijpca.2021.021","DOIUrl":"https://doi.org/10.18231/j.ijpca.2021.021","url":null,"abstract":"Three-dimensional protein structure prediction from amino acid sequence has been a thought-provoking task for decades, but it of pivotal importance as it provides a better understanding of its function. In recent years, the methods for prediction of protein structures have advanced considerably. Computational techniques and increase in protein sequence and structure databases have influence the laborious protein structure determination process. Still there is no single method which can predict all the protein structures. In this review, we describe the four stages of protein structure determination. We have also explored the currenttechniques used to uncover the protein structure and highpoint best suitable method for a given protein.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81942079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Formulation and evaluation of dry herbal powder shampoo 干粉香波的配方及评价
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-10-15 DOI: 10.18231/j.ijpca.2021.022
F. Tamboli, Sajid A. Mulani, N. Mali, Yogesh S Kolekar, Anagha S Ajagekar, Shubham J Kamble, Srushti S Dhanal, A. Shinde, Manish Wani
{"title":"Formulation and evaluation of dry herbal powder shampoo","authors":"F. Tamboli, Sajid A. Mulani, N. Mali, Yogesh S Kolekar, Anagha S Ajagekar, Shubham J Kamble, Srushti S Dhanal, A. Shinde, Manish Wani","doi":"10.18231/j.ijpca.2021.022","DOIUrl":"https://doi.org/10.18231/j.ijpca.2021.022","url":null,"abstract":"Shampoos are used not only for cleansing purpose but also for imparting gloss to hair and to maintain their manageability and oiliness for hair. Shampoos are of various types, like powder shampoo, clear liquid shampoo liquid shampoo, lotion shampoo, solid gel shampoo, medicated shampoo, liquid herbal shampoo etc. As far as herbal shampoos are concerned in stability criteria. Depending upon the nature of the ingredients they may be simple or plain shampoo, antiseptic or antidandruff.In the present work the herbal shampoo powder has been developed, by using traditional drugs for hair care. The preparation were formulated using Onion Powder, Rose Petal, Lemon Grass, Flaxseed or Linseed, Hirda, Bahera, Black tea, Brahmni, Triphala, Bhringraj, Ginger Root, Ashwagadha, Shikakai, Feenu greek, Shatavari, Heena, Wala, Aloevera Powder, Nirgudi Powder, Bavachi, Jatha mansi, Tulsi, Neem, Hibiscus Flower, and Retha evaluated for organoleptic properties, powder characteristics, foam test and physical evaluation.The physicochemical evaluation of the formulated shampoo showed ideal results. However, to improve its quality, product performance, and safety, further development and study was required.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90414869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Simultaneous analysis of eprosartan and hydrochlorothiazide in tablet formulation by High- Performance thin layer chromatography with ultraviolet absorption densitometry 高效薄层色谱-紫外吸收密度法同时分析片剂中依普沙坦和氢氯噻嗪的含量
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-10-15 DOI: 10.18231/j.ijpca.2021.024
V. Tambe, V. Vichare, Anupa Wagh, Surekha Wavhal
{"title":"Simultaneous analysis of eprosartan and hydrochlorothiazide in tablet formulation by High- Performance thin layer chromatography with ultraviolet absorption densitometry","authors":"V. Tambe, V. Vichare, Anupa Wagh, Surekha Wavhal","doi":"10.18231/j.ijpca.2021.024","DOIUrl":"https://doi.org/10.18231/j.ijpca.2021.024","url":null,"abstract":"A new, simple, accurate, and precise high-performance thin-layer chromatographic method has been established for simultaneous analysis of Eprosartan and Hydrochlorothiazide from a tablet formulation. Standard and sample solutions of Eprosartan and Hydrochlorothiazide were applied to precoated 250 μm layer of silica gel G 60 F and the plates were developed with Chloroform: Acetonitrile: Glacial Acetic Acid (7:3:1,v/v/v) as mobile phase. Detection and evaluation of densitograms was performed densitometrically at 254 nm. The linear range was 200-700 ng/band with the retention factors of Eprosartan and Hydrochlorothiazide were 0.26± 0.02 and 0.44±0.02, respectively. The method was validated and successfully used for analysis of the drugs in tablets.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77193627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous estimation of pioglitazone, glimepiride & metformin hydrochloride in bulk & tablet dosage form by UV, RP-HPLC method 紫外、反相高效液相色谱法同时测定原料药和片剂中吡格列酮、格列吡脲、盐酸二甲双胍的含量
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-10-15 DOI: 10.18231/j.ijpca.2021.019
S. S. Shaikh, N. Dighe
{"title":"Simultaneous estimation of pioglitazone, glimepiride & metformin hydrochloride in bulk & tablet dosage form by UV, RP-HPLC method","authors":"S. S. Shaikh, N. Dighe","doi":"10.18231/j.ijpca.2021.019","DOIUrl":"https://doi.org/10.18231/j.ijpca.2021.019","url":null,"abstract":"A stability-indicating UV spectroscopic and high-performance liquid chromatography (RP-HPLC) method is developed for the quantification ofPioglitazone, Glimepiride & Metformin Hydrochloride drug substances. UV spectroscopic method was developed and validated, the wavelength selected for simultaneous estimation were 226nm for pioglitazone, 229nm for glimepiride and 232nm for metformin hydrochloride. The isosbestic point found for the analysis was 229nm. Selected mobile phase was a combination of methanol and water with a ratio of 70% Methanol and 30 % HPLC water with the flow rate of 0.85ml/min. The analyte was analysed on the C18 HPLC column having the pore size of 5 microns at room temperature. The method is validated according to ICH guidelines, the retention time of about 4.0min for metformin, 5.5min for Pioglitazone and 6.8min for Glimepiride was observed. The linearity range with regression co-efficient for Pioglitazone, Glimepiride & Metformin Hydrochloride is 3-15 μg/mL,0.4-1.2 μg/mL and 100-500 μg/mL and 0.9998, 0.9991, 0.9991 respectively.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74887431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Herbal mouthwashes for oral health care-A paradigm shift 口腔保健用草药漱口水——范式转变
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-10-15 DOI: 10.18231/j.ijpca.2021.020
Pavita Kataria, Harpreet Singh, Davinderjit Kaur Shergill
{"title":"Herbal mouthwashes for oral health care-A paradigm shift","authors":"Pavita Kataria, Harpreet Singh, Davinderjit Kaur Shergill","doi":"10.18231/j.ijpca.2021.020","DOIUrl":"https://doi.org/10.18231/j.ijpca.2021.020","url":null,"abstract":"Herbs have been used since centuries to prevent and control various diseases. Being low in cost, safe, and easily available, herbal medicines are staging a comeback globally, owing to their antimicrobial, antifungal, anti-inflammatory, and anti-carcinogenic properties. In dentistry, herbal extracts have been widely used in tooth cleaning agents and mouthrinses. The present study is aimed at reviewing various extracts of herbal products and their effects on dental health. From this review study, it is evidenced that Aloe vera, Neem, Clove Oil, Castor Oil, and Peppermint showed better results than conventional mouthwashes in dental plaque and gingival inflammation reductions. However, preclinical and clinical trials are needed to gauge biocompatibility and safety before herbal medicines are often recommended conclusively for oral care.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76945951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of gastroretentiv floating tablets of losartan potassium by sublimation method 升华法制备氯沙坦钾胃保留浮片
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-07-15 DOI: 10.18231/J.IJPCA.2021.014
Hiral S Bhusara, Ara T Patel, M. Patel
{"title":"Development of gastroretentiv floating tablets of losartan potassium by sublimation method","authors":"Hiral S Bhusara, Ara T Patel, M. Patel","doi":"10.18231/J.IJPCA.2021.014","DOIUrl":"https://doi.org/10.18231/J.IJPCA.2021.014","url":null,"abstract":"The purpose of present study was to formulate and Evaluate Sustained release floating tablet of losartan Potassium using Camphor and Polyethylene Oxide as Pore formation for floating and release retarding agent respectively to improve gastric residence time and patient compliance in management of hypertension. The tablet was prepared by direct compression by using HPMC K4 as dry binder. Camphor and PEO as floating and release retarding agent for sustained release floating tablet. Post compression was done to increase the hardness and floating time of tablet. Release modifier was used to speed up the release of drug from sustained release floating tablet. The effect of two independent variables like amount of Sublimating agent (camphor) and amount of Polyethylene oxide (PEO) on Q30min, Q360min, and Q720min was optimized using 32 factorial design and analyzed using the software design expert 10.0.3. The observed (actual values) responses were coincided well with the predicted values, given by the optimization technique. The floating tablet were characterized by FTIR for drug excipient compatibility.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73228450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review on stability improvement of sugarcane juice by using natural preservatives 天然防腐剂提高甘蔗汁稳定性的研究进展
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-07-15 DOI: 10.18231/J.IJPCA.2021.013
V. Chopade, Kamlesh Mankuskar
{"title":"A review on stability improvement of sugarcane juice by using natural preservatives","authors":"V. Chopade, Kamlesh Mankuskar","doi":"10.18231/J.IJPCA.2021.013","DOIUrl":"https://doi.org/10.18231/J.IJPCA.2021.013","url":null,"abstract":"Sugarcane juice is liquid extract as a drinking beverage in India, possesses therapeutic value. Stability or shelf life is very less due to spoilage or degradation of sugarcane juice because of presence of simple sugar in sugarcane juice. Microorganisms like bacteria prone to degradation of sugarcane juice. Which convert sucrose into dextran as deteriorating agent. Shelf life or stability can be improved by using natural preservatives also chemical preservatives; having a therapeutic value. In this article improvement of stability of sugarcane juice by using natural preservatives such as lemon extract, ginger extract, also may be moringa extract over the chemical preservatives. Citric acid in lemon extract acts as antimicrobial agent while ascorbic acid in ginger extract both improves stability of sugarcane juice. Stabilization of sugarcane juice improved by using naturally obtained preservatives up to several days with good quality.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76673488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fungal strains for mycological production of citric acid 真菌学生产柠檬酸的真菌菌株
International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2021-07-15 DOI: 10.18231/J.IJPCA.2021.012
S. Yadav
{"title":"Fungal strains for mycological production of citric acid","authors":"S. Yadav","doi":"10.18231/J.IJPCA.2021.012","DOIUrl":"https://doi.org/10.18231/J.IJPCA.2021.012","url":null,"abstract":"Citric acid has become an important raw material for general industrial use with many varied and expanding applications such as iron, steel, treatment and conditioning of industrial water supplies, preparation of alkyl resins, paints and in the printing of calico and textile industries. Mycological Production of citric acid includes preparation and sterilization of different media, culture medium, and seedling of culture tube, incubation of culture tubes, determination of citric acid formed and molasses left unfermented during the course of present investigation. The Present work deals mainly selection of potent strains of fungus.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79041907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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