International Journal of Nutrology最新文献

{"title":"The role of intestinal and vaginal dysbiosis in endometrial cancer: an integrative review","authors":"Patrícia Alves de Oliveira Ferreira Sbragi","doi":"10.54448/ijn22305","DOIUrl":"https://doi.org/10.54448/ijn22305","url":null,"abstract":"The increase in the incidence of endometrial neoplasms in the female population is associated with increased life expectancy and the lifestyle adopted in our daily lives. The way we eat influences the profile of our bacterial flora and the production of substances that can work as suppressor tumors or oncogenic. Dysbiosis leads to changes in the intestinal and vaginal bacterial barrier and promotes chronic inflammation and metabolic and hormonal changes that influence the carcinogenesis of gynecological tumors. Chemotherapy treatments can also change the composition of the intestinal microbiota and influence the efficacy and toxic effects, as well as the quality of life of these patients. The use of prebiotics, probiotics, or fecal transplantation can be useful both in prevention and in obtaining better results with chemotherapy treatment and better quality of life. The objective of this review is to provide further elucidation about the interaction mechanisms between the intestinal microbiota and the gynecological tract and assess future perspectives through the modification of the feeding pattern, use of prebiotics, probiotics, and fecal transplant both in the prevention and during the treatment of carrier patients of endometrial neoplasm.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126902653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"II Consensus of the Brazilian Nutrology Association on DHA recommendations during pregnancy, lactation and childhood","authors":"C. A. Nogueira‐de‐Almeida, Durval Ribas Filho, S. Philippi, C. Pimentel, H. Korkes, E. Mello, P. Bertolucci, M. C. Falcão","doi":"10.54448/ijn22302","DOIUrl":"https://doi.org/10.54448/ijn22302","url":null,"abstract":"Objective: To update of the consensus of the Brazilian Association of Nutrology regarding DHA consumption and supplementation during pregnancy, lactation and childhood. Methods: Scientific articles published until 2022 were reviewed in Pubmed/Medline, SciELO and Lilacs databases. Results: Considering the information obtained, the authors drafted the consensus, which was approved by the Brazilian Association of Nutrology board. Conclusions: The recommendations of the Brazilian Nutrology Association are presented based on scientific evidence.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131016984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primeiros 2.200 dias de vida como janela de oportunidade de atuação multidisciplinar relativa à origem desenvolvimentista de saúde e doença: posicionamento da Associação Brasileira de Nutrologia","authors":"C. Nogueira-de-Almeida, Durval Ribas Filho, V. Weffort, Fábio da Veiga Ued, Carla Cristina João Nogueira-de-Almeida, Fábio Baiocco Nogueira, Marcelo Luis Steiner, M. Fisberg","doi":"10.54448/ijn22303","DOIUrl":"https://doi.org/10.54448/ijn22303","url":null,"abstract":"Introdução: A partir do início do século XXI, um novo conceito começou a emergir nos meios científicos e sociais: os primeiros 1.000 dias de vida. Nessa mesma linha um movimento internacional iniciado no mesmo período começou a discutir sobre a “origem desenvolvimentista da saúde e da doença”. Inúmeros problemas que acometem o ser humano em todo seu ciclo de vida têm seu início nos primeiros anos e, muitas vezes, podem ser evitados ou minimizados quando precocemente reconhecidos e abordados. O presente documento discute, com base na literatura científica, a ideia de expansão da janela de oportunidades para um período de 2.200 dias, englobando desde a fase préconcepcional até o final do quinto ano de vida. Métodos: Foram revisados de forma integrativa os artigos científicos publicados até o ano de 2022 nas bases de dados Pubmed/Medline, SciELO, Google Acadêmico e Lilacs, nas línguas portuguesa, inglesa e espanhola. A busca de artigos foi direcionada aos temas referentes a alvos de intervenção que pudessem impactar na saúde presente e futura da criança. Resultados: Foram estudados aspectos biológicos, sociais e psicológicos em cinco fases: préconcepcional, gestacional, primeiro ano, segundo ano e terceiro ao quinto ano de vida. Os dados obtidos mostram a importância de ampliação do período de maior atenção profissional no começo da vida. Conclusão: A Associação Brasileira de Nutrologia recomenda a janela de 2.200 dias (100 dias na pré-concepção + 270 dias de gestação + 1.830 dias do primeiro ao quinto ano de vida) como período ideal de atuação profissional com vistas à garantia de saúde presente e futura das crianças.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130552424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-COVID-19 multisystem inflammatory syndrome in children: a case report","authors":"Tauane Rene Martins, Gabriella Cavalcante Leite, Beatriz Nomada Hauy, G. Marconato, Kamila Cristina Viana, Jaqueline Modaelli, Náthalie Angélica Cardoso Marqui, Marina Lucca de Campos Lima, Rafaela de Fátima Ferreira Baptista, Rawene Elza Veronesi Gonçalves Righetti, A. Mendes","doi":"10.54448/ijn22301","DOIUrl":"https://doi.org/10.54448/ijn22301","url":null,"abstract":"Objective: Report of a case of Multisystem Inflammatory Syndrome in Children (MIS-C) post-COVID 19 and review of articles on the topic. Results: Coronavirus 2 (SARS-CoV-2) infection is a disease whose symptoms are similar between the adult and pediatric population, ranging from asymptomatic cases to more serious conditions that have spread global terror due to the high number of infections worldwide deaths. However, children have presented a milder clinic. It is worth mentioning, however, that this population is not completely risk-free, with reports of the association of the Coronavirus triggering inflammatory diseases, such as the so-called MIS-C whose complications can be as serious as the forms of symptoms experienced by adults. Conclusion: The temporal and serological relationship of a link with SARS-CoV-2 infection is supported by consistent data, however further studies are needed to establish SARS-CoV-2 as an inciting agent. Due to the severity of MIS-C, knowledge about this disease is necessary for a quick diagnosis and early treatment, aiming to reduce systemic lesions. Due to the increase in the number of cases of children affected by MIS-C, the use of immunomodulatory drugs, such as intravenous immunoglobulin (IVIG), aspirin, and systemic glucocorticoids, has been instituted as first-line therapy, to reduce inflammation and late complications.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132965902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the nutritional profile through the 24-hour record in truckers in the central-southern Brazilian region: a prospective observational cross-sectional study","authors":"Giovanna Rodrigues de Castro Castellani, Maria Clara Machado Wintruff, Rafaela Melin Miranda, Danilo Prandi de Carvalho, Ricardo Malheiro Dourado, Vinicius Augusto Ferreira Baptista, Tainara Costa, Durval Ribas Filho","doi":"10.54448/ijn22s104","DOIUrl":"https://doi.org/10.54448/ijn22s104","url":null,"abstract":"Introduction: Truck drivers are of great importance to the Brazilian economy. The exorbitant workload and long periods away from home are causes of the adoption of unhealthy eating habits, such as the intake of foods that are sources of lipids with high caloric value. Extensive travel contributes to a sedentary lifestyle. This causes health damage and comorbidities such as diabetes, obesity, hypertension, stress, and depression. Based on these considerations, the present study evaluates the nutritional profile of truck drivers. Objective: It was to evaluate the food quality of truck drivers in the Center-South Geoeconomic Region of the country, comparing the portions of macronutrients consumed with those recommended by the Brazilian Food Pyramid. Methods: Observational and cross-sectional study. The consumption of macronutrients by 100 truck drivers from the states of São Paulo, Minas Gerais, Mato Grosso do Sul and Goiás was qualitatively evaluated. The research used 24-hour food recalls, completed online, via Google Forms, between June and September 2020. Statistical analysis was obtained by calculating the Wilcoxon's non-parametric test to compare the medians of ingested portions and the ideas. Results: The Wilcoxon test identified significant differences between the number of servings consumed by truck drivers and the recommended ideal with regard to fruits, vegetables/vegetables, oils/fats, meats/eggs, sweets/sugars, milk, cheese and derivatives (p<0.0001). Only the portions of carbohydrates were in accordance with the nutritional recommendations, that is, six portions a day (ns). In the class of sugars and sweets, consumption four times higher than recommended was observed. In the meat and eggs category, consumption was double the ideal. In oils and fats, triple the recommended value. The consumption of milk and dairy products is three times less than ideal, such as vegetables. Finally, the average value of fruit portions eaten by truck drivers was zero, while the recommended value is three. Conclusion: Among the food groups analyzed, carbohydrates were the only group in which consumption was adequate. There was a significant excess of sweets and fats intake by truck drivers, when compared to the ideal amount indicated by the food pyramid. The intake of milk and dairy products, vegetables and legumes was deficient, three times lower than recommended. Fruits counted as a median intake value of zero servings.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130976689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caffeine ingestion by students at the Brazil faculty of medicine: a prospective observational cross-sectional study","authors":"Marília Vilela Galhardo, Bárbara Lopes Osaki, Paula Reis Violla, Fernando Panini Rodrigues, Aléxia Gobete da Silva, Tainara Costa, Durval Ribas Filho","doi":"10.54448/ijn22s103","DOIUrl":"https://doi.org/10.54448/ijn22s103","url":null,"abstract":"Introduction: In higher education, the consumption of stimulant substances such as coffee is increasing intensely due to the high demand of concentration and disposition of individuals. This occurs mainly among medical students. Objective: It was to quantify and analyze caffeine intake and its effects on medical students at the Faculty of Medicine of Catanduva, Centro Universitário Padre Albino (UNIFIPA). Methods: This study followed a prospective observational cross-sectional model, following the rules of clinical research of the STROBE. Data collection took place from June 2019, through an objective questionnaire and self-application, which was answered by students from the first to the sixth year of FAMECA who were interested in answering and contributing to the research, which had as objective to quantify and analyze the use of caffeine, in addition to its motivations and side effects on the physiology of these students. This study was analyzed and approved by the Research Ethics Committee according to a substantiated opinion number 5,347,594, and obtaining the Informed Consent Form. For data analysis, a common descriptive analysis was performed, obtaining the values of total N, and statistical percentage (%) for all predictors. The One-Way test (ANOVA) was applied, adopting the α level lower than 0.05, with a statistically significant difference for the 95% CI. Results and Conclusion: The results of this study revealed that a very large number of university students ingest caffeine. Most of the students started consumption in the pre-college course and in college, with the aim of compensating for sleep, because they like the taste of energy drinks and improve academic performance, due to the intense routine due to the high workload requires greater attention, in order to to meet the demand for studies. Most students consume moderately caffeine, which is not harmful to health. However, a minority ingest excessive amounts of substances that contain caffeine and side effects are noted. Among these, the ones that stood out were stomach problems, anxiety and tachycardia. Thus, even representing the minority, it is of fundamental importance to carry out more studies on this topic. With this, it will be possible to provide more information to the population so that it is able to assess the impacts of the use of stimulants in clinical practice, in order to minimize possible adverse effects. Finally, the population will be able to use caffeine properly, according to the recommended dose, avoiding major health problems.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122105383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"False hyperparathyroids secondary to biotin prolonged use: a case report","authors":"Georgeanne Neves, E. Lira","doi":"10.54448/ijn22207","DOIUrl":"https://doi.org/10.54448/ijn22207","url":null,"abstract":"A 55-year-old overweight female patient with elevated parathyroid hormone (PTH) levels, without any other major plasma biochemical abnormalities, and with normal vitamin D and calcium levels. The condition was suggestive of normocalcemic primary hyperparathyroidism. Bone densitometry and 24-hour calciuria were normal. After extensive investigation and possible referral for exploratory surgery, the patient reported continued and chronic use of biotin supplementation (2.5 mg per day). Repeated tests after discontinuing the use of vitamin B7 showed normal PTH levels without surgical or pharmacological interventions. Biotin supplementation associated with the use of this vitamin as a component of biological assays for hormone dosage can generate incorrect laboratory results, which puts medical conduct at risk with inaccurate diagnoses and unnecessary procedures. Although, different substances or emotional conditions can interfere with hormone dosages, one must consider the use of food supplements such as biotin since it can also generate unreliable results. Discontinuation of the use of biotin, in addition to the assessment of serum biotin levels prior to hormone dosing is necessary for a correct evaluation of serum PTH levels. This study was analyzed and approved by the Research Ethics Committee, and obtaining the Informed Consent Form according to CNS/CONEP Resolution 466/12.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123874651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifestyle under the light of nutrological and psychological aspects in the COVID-19 pandemic: a systematic review","authors":"Lorena Gigli","doi":"10.54448/ijn22206","DOIUrl":"https://doi.org/10.54448/ijn22206","url":null,"abstract":"Introduction: Due to the emergence of the new coronavirus (whose disease is COVID-19), in 2020 the WHO declared COVID-19 a global pandemic. Preventive measures can radically change individuals' daily habits, including lifestyle-related behaviors. Sedentary behavior, anxiety, and boredom caused by home confinement can influence motivation to eat and change lifestyle patterns. Objective: To carry out a systematic review on the impacts of COVID-19 on people's diet and lifestyle, as well as to point out the main dietary and lifestyle precautions during and after the new coronavirus pandemic, based on the results of clinical studies. Methods: The rules of the Systematic Review-PRISMA Platform were followed. The search was carried out from December 2021 to April 2022 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: Were found 264 articles. A total of 116 articles were fully evaluated and 34 studies were developed in a systematic review. There is scientific evidence that foods/nutrients and natural substances from human physiology and biochemistry such as melatonin and coenzyme Q10 control immune system functions, and many metabolic or chronic diseases have been implicated in poor diet and lifestyle. The results of the pandemic indicate there have been a variety of lifestyle changes, physical inactivity, and psychological problems. Still, adults over 40 years old, with children, unemployed, and those living in a macroeconomic region were shown to be more exposed to unhealthy behaviors. Maintaining dietary intervention through telemedicine can reduce the negative impact of eating habits and physical activity patterns.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123992591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Major clinical outcomes of melatonin use in COVID-19 patients: a systematic review","authors":"Mariana Tolentino Chaves, A. P. Chaves","doi":"10.54448/ijn22208","DOIUrl":"https://doi.org/10.54448/ijn22208","url":null,"abstract":"Introduction: In the context of the Sars-Cov-2 (COVID-19) pandemic, as well as other viral infections, these viruses can lead to significant morbidity and mortality. Thus, in the context of melatonin science in viral infections such as influenza and COVID-19, there is a growing realization that the regulation of melatonin pathways, both pineal and systemic, may be an important aspect of the regulation of viruses in cellular functions. Objective: It was to list the main results of clinical studies of the use of melatonin in patients infected with Sars-Cov-2 through a systematic review. Methods: The rules of the Systematic Review-PRISMA Platform. The search was carried out from December 2021 to April 2022 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: It was found 164 articles. A total of 86 articles were fully evaluated and 30 studies were developed in a systematic review. Melatonin is known as an anti-inflammatory agent and immune modulator that may address the progressive pathophysiology of coronavirus disease 2019 (COVID-19). According to the objective and results obtained in the present study that evaluated the treatment in patients with COVID-19, the use of melatonin can help reduce thrombosis, sepsis and mortality. Furthermore, the combination of 3.0 mg oral melatonin tablets and standard care can substantially improve sleep quality and blood oxygen saturation in hospitalized patients. Clinical symptoms such as cough, dyspnea and fatigue, as well as the polymerase chain reaction (PCR) level and lung involvement in patients receiving melatonin can improve significantly. Also, the mean time of patients' hospital discharge and return to initial health was significantly shorter in patients who received melatonin compared to the control group. There was evidence of benefit of sustained-release melatonin 2 mg in therapy in patients, as well as evidence that the use of melatonin was associated with a reduced probability of a positive SARS-CoV-2 test result compared to the use of blockers of the angiotensin II receptor or angiotensin-converting enzyme inhibitors.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128314091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Major clinical findings of β-alanine in sports performance: a systematic review","authors":"Leandro Reis Woitas, J. Ribas","doi":"10.54448/ijn22205","DOIUrl":"https://doi.org/10.54448/ijn22205","url":null,"abstract":"Introduction: Dietary supplements offer ergogenic aid in an attempt to increase energy, improve recovery and modulate body composition, enabling improved performance. Thus, β-alanine is a substrate of carnosine and is becoming an ergogenic aid for sports performance. Objective: To carry out a systematic review to highlight the main scientific evidence on the improvement of sports performance with the use of β-alanine. Methods: The PRISMA Platform rules were used. The research was developed using the SCOPUS, PUBMED, and SCIENCE DIRECT databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: Studies have shown that β-alanine has an important ergogenic role in sports performance. Weeks of beta-alanine supplementation (4-6g per day) significantly increases muscle carnosine concentrations. The only side effect reported is paresthesia. Beta-alanine attenuates neuromuscular fatigue, particularly in older individuals. Also, combining beta-alanine with other supplements can be advantageous when beta-alanine supplementation is high enough (4-6 g per day) and long enough (minimum 4 weeks).","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122745978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}