儿童covid -19后多系统炎症综合征1例报告

Tauane Rene Martins, Gabriella Cavalcante Leite, Beatriz Nomada Hauy, G. Marconato, Kamila Cristina Viana, Jaqueline Modaelli, Náthalie Angélica Cardoso Marqui, Marina Lucca de Campos Lima, Rafaela de Fátima Ferreira Baptista, Rawene Elza Veronesi Gonçalves Righetti, A. Mendes
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摘要

目的:报告1例新冠肺炎后儿童多系统炎症综合征(MIS-C)并复习相关文献。结果:冠状病毒2型(SARS-CoV-2)感染是一种症状在成人和儿科人群中相似的疾病,从无症状病例到更严重的情况,由于全球感染死亡人数众多,已在全球传播恐慌。然而,孩子们却表现得较为温和。然而,值得一提的是,这一人群并非完全没有风险,有报道称冠状病毒与引发炎症性疾病有关,例如所谓的misc,其并发症可能与成年人经历的症状形式一样严重。结论:与SARS-CoV-2感染相关的时间和血清学关系得到一致数据的支持,但需要进一步研究以确定SARS-CoV-2是否为刺激剂。由于MIS-C的严重程度,了解这种疾病对于快速诊断和早期治疗是必要的,目的是减少全身病变。由于受MIS-C影响的儿童病例数量的增加,免疫调节药物的使用,如静脉注射免疫球蛋白(IVIG)、阿司匹林和全身糖皮质激素,已被确立为一线治疗,以减少炎症和晚期并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Post-COVID-19 multisystem inflammatory syndrome in children: a case report
Objective: Report of a case of Multisystem Inflammatory Syndrome in Children (MIS-C) post-COVID 19 and review of articles on the topic. Results: Coronavirus 2 (SARS-CoV-2) infection is a disease whose symptoms are similar between the adult and pediatric population, ranging from asymptomatic cases to more serious conditions that have spread global terror due to the high number of infections worldwide deaths. However, children have presented a milder clinic. It is worth mentioning, however, that this population is not completely risk-free, with reports of the association of the Coronavirus triggering inflammatory diseases, such as the so-called MIS-C whose complications can be as serious as the forms of symptoms experienced by adults. Conclusion: The temporal and serological relationship of a link with SARS-CoV-2 infection is supported by consistent data, however further studies are needed to establish SARS-CoV-2 as an inciting agent. Due to the severity of MIS-C, knowledge about this disease is necessary for a quick diagnosis and early treatment, aiming to reduce systemic lesions. Due to the increase in the number of cases of children affected by MIS-C, the use of immunomodulatory drugs, such as intravenous immunoglobulin (IVIG), aspirin, and systemic glucocorticoids, has been instituted as first-line therapy, to reduce inflammation and late complications.
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