International Journal of Nutrology最新文献

{"title":"Obsesity: a view on treatment","authors":"Luca Campassi Bonini, Lucas Antônio Alves Consoleto, Lucas Maluli Maluf Silva, Mateus Sartori de Oliveira Souza, Vinícius Mendes Soares, Durval Ribas Filho","doi":"10.54448/ijn22402","DOIUrl":"https://doi.org/10.54448/ijn22402","url":null,"abstract":"Obesity is a disease stigmatized by society in general. Many tend not to consider it a disease, which makes it difficult to treat and worsens the pandemic generated by this condition. Considering the seriousness with which health professionals must face this problem, a form was applied to 511 Brazilian academic medical students, to understand how these students see this disease and how to treat it. The results showed that there is a tendency for incoming students to opt for diet therapy associated with physical exercises, while students further on consider the use of drugs associated with diet therapy and physical exercises the best strategy. This shows the importance of medical schools providing solid information about obesity and its treatment, showing that in certain cases it is not enough for the patient to follow a diet and exercise. This change in the view of health professionals, therefore, would be a way to fight the pandemic in question.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"412 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133599676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental origins of health and disease (DOHaD) and its impacts on children's health: a systematic review","authors":"Mayra Jazmila Ramirez Leguizamon","doi":"10.54448/ijn22404","DOIUrl":"https://doi.org/10.54448/ijn22404","url":null,"abstract":"The general objective of this study is to elucidate how studies linked to the Developmental Origins of Health and Diseases (DOHaD) relate to pregnancy, children's health, and the possibility of developing non-communicable diseases (NCDs). The research method chosen for its scope was based on bibliographic, qualitative, and descriptive research. Among the results obtained, it was possible to show that since the 1980s when the first studies within the DOHaD scope were published to the present, numerous advances have been consolidated and there is still a vast field of study to be developed. It is concluded that the external environment can affect the development of the fetus in the intrauterine environment, increasing vulnerability to the development of non-communicable diseases (NCDs) in adult life, such as type II diabetes, malnutrition, and obesity, among countless other problems. that can manifest in adulthood. Therefore, it is essential that the pregnant woman has specialized care from the first months, at birth, and then as the child grows and develops.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131470948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of leucine in the activation of cellular metabolism: a large integrative review","authors":"Amir Salomão Gebrin, I. J. Zotarelli-Filho","doi":"10.54448/ijn22s201","DOIUrl":"https://doi.org/10.54448/ijn22s201","url":null,"abstract":"This review addressed the signaling of cellular activation by leucine, discussed the risks of excessive signaling by proteins in the Western diet, and explored the potential of leucine stimulation in tissue regeneration. As result, amino acids are, in addition to building blocks of macromolecules, cellular activation signals. Essential amino acids are not produced by animals and leucine appears to be the main signaling amino acid. Mammals adjusted the cell activation and growth rate of their young by the leucine concentration of the milk produced. Several studies demonstrate the benefits of leucine supplementation in preventing sarcopenia, improving muscle and liver performance, as well as a possible neuroprotective role in head trauma and dementia. However, its excess, so common in the Western diet, is related to obesity, type II diabetes, neurodegenerative diseases, and cancer. The mTORC1 kinase integrates cellular activation stimuli from macro protein synthesis to epigenetic regulation. Controlling mTORC1 activity by consuming leucine can prevent, treat, or cause disease. A greater understanding of the regulatory effects of leucine and mTOR in unstable tissues such as tumors or fragile tissues such as the CNS are areas of great relevance and with extensive fields still to be explored.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128313715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between nutrology and oral health: a systematic review of major clinical findings","authors":"V. T. Yamaguchi, D. Silva, Felipe Thomaz Diogo de Oliveira, E. Kassis","doi":"10.54448/ijn22401","DOIUrl":"https://doi.org/10.54448/ijn22401","url":null,"abstract":"Introduction: Food and nutrition are fundamental in maintaining the general and oral health of populations. Health status can be affected by nutrient deficiency and vice versa. Dietary guidelines were developed to provide evidence-based food and beverage recommendations to populations to promote a diet that meets nutritional needs and prevents diet-related illness. Objective: Aimed to carry out a concise systematic review to elucidate through clinical studies the real relationship between nutrition and oral health. Methods: The rules of the Systematic Review-PRISMA Platform. The research was carried out from August to October 2022 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, using scientific articles from 2005 to 2022. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 125 articles were found. In total, 75 articles were fully evaluated and 35 were included and evaluated in this systematic review. It was concluded that food and nutrition are fundamental in maintaining the general and oral health of populations. Health status can be affected by nutrient deficiency and vice versa. Nutrology can promote a diet that meets nutritional needs and prevent diet-related diseases such as tooth decay. It was evidenced that malnutrition can significantly affect oral health and vice versa. A diet lacking in nutrients can lead to the progression of oral cavity disease by altering tissue homeostasis, reducing resistance to microbial biofilm, and decreasing tissue healing. It can also affect the development of the oral cavity.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134452860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Major approaches to melatonin and nutrients regulation in the bone regeneration process with exosomes and microRNAs: a systematic review","authors":"Danillo Gomes Leite","doi":"10.54448/ijn22309","DOIUrl":"https://doi.org/10.54448/ijn22309","url":null,"abstract":"Introduction: Bone diseases comprise a large group of common diseases, including fractures, osteoporosis, and osteoarthritis that affect a large number of individuals. Without intervention, the prevalence of osteopenia is projected to increase to 64.3 million Americans and that of osteoporosis to 11.9 million by the year 2030. Melatonin exerts numerous physiological effects, including the induction of anti-inflammatory and antioxidants, resetting circadian rhythms, and promoting wound healing and tissue regeneration, participating in the maintenance and regenerative processes of bones and cartilage. Objective: A systematic review was carried out to present the state of the art of melatonin regulation, mesenchymal stem cells, exosomes, microRNAs, and nutrients in the bone regeneration process. Methods: The systematic review rules (PRISMA) were followed. The search was carried out from July to September 2022 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases, using scientific articles from 2019 to 2022. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 126 articles were found. A total of 59 articles were fully evaluated and 46 were included in this systematic review. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 9 studies at high risk of bias and 24 studies that did not meet the GRADE. Most studies showed homogeneity in their results, with I2 =97.8%>50%. The symmetrical funnel plot does not suggest a risk of bias between small sample-size studies. Based on the results, melatonin has important functions in regulating the regenerative activities of mesenchymal stem cells that modulate, together with nutrients, the activities of exosomes and microRNAs in the bone regeneration process.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127108092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrological and metabolic approaches to the action of the some special micronutrients in heart failure and metabolic syndrome: a systematic review","authors":"Vanessa Piovesan Freitas Assumpção, Otávio Queiroz Assumpção","doi":"10.54448/ijn22308","DOIUrl":"https://doi.org/10.54448/ijn22308","url":null,"abstract":"Introduction: In the heart disease scenario, heart failure (HF) is the leading cause of hospitalizations in the United States in patients over 65 years of age, and there is evidence that this pathology affects 26 million people worldwide. Dietary guidance for patients with HF has focused on sodium restriction and fluid intake, but diet quality is often poor in HF patients and can contribute to morbidity and mortality. Restrictive diets can lead to inadequate intake of macro and micronutrients by patients with HF, highlighting deficiencies in calcium, magnesium, coenzyme Q10, zinc, iron, thiamine, vitamins D, E, and K, and folate. Objective: Through a systematic literature review, the main nutrological approaches to the action of the micronutrients magnesium, coenzyme Q10, and vitamin D in heart failure and metabolic syndrome were evidenced. Methods: The present study followed a concise systematic review model (PRISMA). The literary search process was carried out from August 2022 to September 2022 and was developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, using scientific articles from 1998 to 2022. The low quality of evidence was attributed to reports of cases, editorials, and brief communications, according to the GRADE instrument. The risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: The total of 136 studies were found for eligibility analysis, and then 75 of the 84 total studies were selected for this systematic review. According to the GRADE instrument, most studies showed homogeneity in their results, with I2 =98.7% >50%. The Funnel Plot showed a symmetrical behavior, not suggesting a significant risk of bias in studies with smaller sample sizes. Studies have shown that magnesium deficiency or changes in its metabolism are related to the pathophysiology of heart failure, hypertension, arrhythmias, preeclampsia, insulin resistance, and diabetes. Vitamin D plays an important role in innate and adaptive immune responses, cell cycle, and metabolic processes, evidenced by the reported relationship between its deficiency and the prevalence of immunity-mediated disorders, cancer, and cardiometabolic diseases. The VDR results in β cells, endothelium, cardiac myocytes, and renin production suggesting a role for vitamin D in these diseases. Coenzyme Q10 is part of the electron transport chain and is found in large concentrations in the mitochondrial, especially in the muscles, brain, and heart. Clinical studies have shown that pathologies such as acute myocardial infarction, arterial hypertension, and myopathies induced by statins, physical fatigue inherent in physical exercise, male infertility, preeclampsia, Parkinson's disease, periodontal disease, and migraine had low plasma concentrations of coenzyme Q10.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124638150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Major evidence of nutrological regulation in obese patients with meta-inflammation: a systematic review","authors":"Paulo Mageste Lessa, Karla Dias Barbosa Lessa, Bruno de Souza Oliveira, Ricardo Siqueira Barroso Filho, Maria Laura Palmeira Rajab","doi":"10.54448/ijn22307","DOIUrl":"https://doi.org/10.54448/ijn22307","url":null,"abstract":"Introduction: Obesity stands out as a multifactorial disease that can cause several public health problems. There are 2.0 billion overweight and obese people in the world, and Brazil ranks fifth in the world. A healthy nutritional status promotes immune function and can prevent the onset of a serious inflammatory process and severe infections, especially in times of a pandemic such as COVID-19. Objective: It was to highlight the main clinical considerations of nutrological and dietary regulation in obese patients with marked inflammatory processes and meta-inflammation through a systematic review. Methods: The systematic review rules of the PRISMA Platform were followed. The research was carried out from August to September 2022 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 127 articles were found. A total of 74 articles were fully evaluated and 29 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 32 studies at high risk of bias and 25 studies that did not meet the GRADE. Research has shown that unbalanced dietary patterns, such as the Western diet, rich in simple sugars, refined carbohydrates, and saturated and trans fatty acids, lead to chronic inflammatory responses, increased fat deposits, and future comorbidities associated with overweight and obesity. Caloric restriction decreased polymerase chain reaction (PCR) in obese patients and diet administration over 12 weeks had a beneficial effect. Furthermore, obese patients with antioxidant supplementation had lower values of BMI, waist circumference, fasting blood glucose level, and insulin resistance homeostasis model assessment when compared to the placebo group, as well as lower total cholesterol levels, triglycerides, LDL, malondialdehyde and tumor necrosis factor-alpha. Supplementation of n-3 PUFA can significantly reduce serum PCR, tumor necrosis factor α (TNFα), and interleukin 6 (IL-6) concentrations.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126921736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of premenstrual syndrome and its relationship with changes in food consumption during the luteal phase in a university center in northwest paulista: a prospective observational cross-sectional study","authors":"Beatriz Rosa Meneghesso, Giulia Rago Constâncio, Marina Morandin Rinaldi, Nayara Ferreira e Silva, Pedro Tadeu Dalmaso, Vitória Zanqueta Marcello, Aline Damasceno de Avance, Durval Ribas Filho, Tainara Costa","doi":"10.54448/ijn2236","DOIUrl":"https://doi.org/10.54448/ijn2236","url":null,"abstract":"Introduction: The menstrual cycle is a natural phenomenon that occurs in two phases: follicular and luteal. Several hormonal, physical and psychological changes occur during this period, which influence the female diet. These changes and consequences are felt mainly in the luteal phase, that is between 1 to 5 days before the menstrual flow, characterizing the premenstrual syndrome (PMS) or premenstrual tension (PMS). Objective: This article aims to evaluate food intake and dietary changes in adult women of reproductive age during the luteal phase of the menstrual cycle. Methods: Quali-quantitative descriptive exploratory study, carried out with 207 female students, between 18 and 41 years of age, from all courses at a University Center in northwestern São Paulo. An online questionnaire was applied via Google Forms with closed and open questions that characterized the sample regarding the participants' personal and dietary aspects in the luteal phase. The work complied with Resolution 466/12 of the National Health Council and was approved by the Ethics Committee and all participants signed the Informed Consent Term. Results: It was observed that there was a predominance of women aged between 19 and 22 years (64.25%). With regard to physical symptoms in the luteal phase, 95.65% of women reported having at least one symptom, such as swollen and/or painful breasts (67.7%) and colic (55.1%). Regarding the intensity of food craving, 5.3% of the women reported no changes, 10.6% had low intensity (mild), 50.7% had moderate intensity, 27.5% had high intensity (high) and 5, 8% very high intensity (severe). According to the change in dietary pattern, among the foods presented, 85% of the participants claimed to have a higher consumption of sugars and sweets during this period and 38.6% higher consumption of carbohydrates, representing most of the responses collected. It was found that food cravings among the participants occurred with high frequency in 91.78% of the cases, with emphasis on the high craving for sweets (87%) and fast food (33.8%). The increase in food consumption in the luteal phase was significant, as it was present in 70.5% of women. Conclusion: The luteal phase interferes with the pattern and intensity of food craving, as well as with the increased intake of macronutrients, especially carbohydrates, sugars and sweets.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"47 22","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113993185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anais XXVI Congresso Brasileiro de Nutrologia - n. 26, v. 1, 2022","authors":"C. Nogueira-de-Almeida, Durval Ribas-Filho","doi":"10.54448/abran2022","DOIUrl":"https://doi.org/10.54448/abran2022","url":null,"abstract":"O XXVI Congresso Nacional de Nutrologia é o maior evento de nutrologia da América Latina e, em 2022, tem como objetivo geral transmitir conhecimentos científicos e atuais com palestrantes de renome nacional e internacional.Além disso, promove o envolvimento de acadêmicos, médicos, nutricionistas, psicólogos na elaboração e apresentação de trabalhos científicos, visando fomentar a produção científica na nossa área.Desejamos que todo o conteúdo aqui apresentado seja de grande utilidade na aplicação do seu trabalho, no dia a dia, contribuindo para a honra dos princípios da Nutrologia, que é promover saúde e bem-estar.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131334573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudohipoaldosteronism Type 1: a case report supported by a literature review","authors":"Natália Cavalheiro Braz Fernandes, Davi Cassiano Ueda Simensato, Leonardo Jordan Hansen Vizzotto, R. S. Haber, Camila Garcia Ferrari Jacob, Amanda Salemme Orlando Sanches, F. Piazzon, Francisco de Agostinho Junior, Luiza Santos de Argollo Haber, J. Haber","doi":"10.54448/ijn22304","DOIUrl":"https://doi.org/10.54448/ijn22304","url":null,"abstract":"In the neonatal period, hydro electrolytic disorders with dehydration and metabolic acidosis can cause admission to an intensive care unit and become a diagnostic challenge. Among such disorders, hyponatremia and hyperkalemia become diagnostic challenges with hormonal involvement, including aldosterone. Pseudohypoaldosteronism (PHA) resulting from the lack of response to aldosterone in target cells can be classified into three types and its suspected diagnosis in cases of hyponatremia, hyperkalemia with an elevation of serum aldosterone, can be confirmed by exome sequencing with identification of a potentially pathogenic. This study was based on the case report of a newborn of consanguineous parents who, after birth, evolved in the first week of life with shock, hyponatremia, hyperkalemia, and metabolic acidosis. An initial investigation ruled out congenital adrenal hyperplasia. The presence of hyperaldosteronism with increased plasma renin activity, associated with hyperkalemia and hyponatremia difficult to control with electrolyte replacement, led to a molecular investigation that confirmed PHA type 1 by a mutation in the SCCN1A gene. In neonates with severe hyponatremia that is difficult to resolve with conventional treatment and elevation of serum aldosterone, this pathology must be remembered and investigated, avoiding high morbidity and mortality.","PeriodicalId":137919,"journal":{"name":"International Journal of Nutrology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134465727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}