Badreldin Mohamed, George Simmons, Khalid M. Bhatti, S. Taha, Abdalla Hassan, Muhammad Chauhan, S. Babikir, M. Mohamed, D. Mirghani, R. Canelo
{"title":"Tubogram, A Useful Investigation for Evaluation of Patients Post Cholecystostomy Drain for Acute Cholecystitis, Single Centre Experience","authors":"Badreldin Mohamed, George Simmons, Khalid M. Bhatti, S. Taha, Abdalla Hassan, Muhammad Chauhan, S. Babikir, M. Mohamed, D. Mirghani, R. Canelo","doi":"10.59657/2837-8172.brs.23.006","DOIUrl":"https://doi.org/10.59657/2837-8172.brs.23.006","url":null,"abstract":"Background: Laparoscopic cholecystectomy (LC) is the gold standard treatment for cholecystitis. However, for co-morbid or unstable patients, a less invasive approach can be adopted such as cholecystostomy drain (CD) insertion. CD can be a bridging operation or can be used as a definitive treatment if patient unsuitable for surgery. Methods: Retrospective study of patients who had Tubogram at Cumberland Infirmary, post CD for non-malignant cause between January 2019 and January 2022, comparing their outcome with the patients who did not undergo tubogram investigation. Patient data list collected from information department, Cumberland Infirmary. Results: Cholecystostomy drain placed for 58 patients; 21 patient (36.21%) had tubogram. Of the 58,44 patients (75.86%) had one CD; only 10 patients (22.73%) of them had tubogram. 14 patients had more than one CD (11 patient of them had tubogram). 66.67% patients had tubogram at 3-4 weeks following CD insertion. Outcome of tubogram patients was 47.62% (n=10) had Laparoscopic Cholecystectomy (LC) 6 weeks after cholecystostomy drain removal and 28.57% (n=6) had Endoscopic retrograde cholangiography then Laparoscopic Cholecystectomy. Non-tubogram patients’ group had more visits to same day emergency clinic comparing to tubogram patients’ group. Conclusion: Tubogram is a useful, cheap, non-invasive test linked with lower recurrence rate of cholecystitis symptoms after removal of CD; it is also associated with earlier CD removal. We recommend that tubogram should be a routine investigation for all patients three to four weeks post CD insertion.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"147 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83040411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Slaoui, Babty Mouftah, A. Slaoui, Y. Himmi, Amine El Affari, O. Zineddine, Taha Yassine Abboudech, Z. Bernoussi, T. Karmouni, K. El khader, Aziz Baydada, A. Kharbach, A. Koutani, Ahmen Ibn Attya Andaloussi
{"title":"Bladder Paraganglioma: Report of Two Cases and A Literature Review","authors":"A. Slaoui, Babty Mouftah, A. Slaoui, Y. Himmi, Amine El Affari, O. Zineddine, Taha Yassine Abboudech, Z. Bernoussi, T. Karmouni, K. El khader, Aziz Baydada, A. Kharbach, A. Koutani, Ahmen Ibn Attya Andaloussi","doi":"10.59657/2837-8172.brs.23.004","DOIUrl":"https://doi.org/10.59657/2837-8172.brs.23.004","url":null,"abstract":"Objective: We report two incidental cases of bladder paraganglioma and a review of the literature published to date. Methods: Medline was searched for the last 10 years for the terms \"paraganglioma\" and \"urinary\" and \"bladder\". Results: Bladder paraganglioma (BP) is extremely rare. It represents 10% of all paragangliomas and concerns less than 0.06% of bladder tumors. Often discovered by chance, it can nevertheless be symptomatic, particularly during micturition. The most common symptoms are hematuria, hypertension and headache. About 14% of these tumors are malignant and radio-chemically resistant. Surgery is therefore the cornerstone of treatment. We recommend, cystoscopy, partial cystectomy and regular follow-up based on regular cystoscopy and imaging. Their rarity explains why, at present, there are no recommendations for treatment and monitoring. However, their risk of malignancy recurrence and metastasis requires regular and long-term follow-up. Conclusions: Bladder paragangliomas are rare tumors. Treatment should be based on partial cystectomy and their follow-up should be regular.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81789455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute Pulmonary Embolism with Multiple Septic Emboli and Pulmonary Infarcts in an IV Drug Abuser with Right-Sided Endocarditis: A Case Report","authors":"Anup Regmi, Nirmal Prasad Neupane, Aishath Naura, Kritisha Rajlawot","doi":"10.59657/2837-8172.brs.23.007","DOIUrl":"https://doi.org/10.59657/2837-8172.brs.23.007","url":null,"abstract":"This case report describes the imaging findings of septic pulmonary embolism (SPE) in a 30-year-old male with a history of intravenous drug abuse for one year. The patient initially presented with high grade fever, shortness of breath, and cough in the emergency department of our institution. The patient was evaluated by chest X-ray, blood cultures, echocardiography, and CT pulmonary angiography which confirmed the diagnosis of SPE, and the causative organism was confirmed to be Staphylococcus aureus. In this case report, we discuss the Chest X-ray findings, and characteristic CT imaging findings of SPE and describe the role of different imaging modalities in the timely diagnosis and management of this highly fatal condition.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"253 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76969092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariam Mahtate, A. Slaoui, Soukaina Cherradi, N. Zeraidi, A. Lakhdar, A. Kharbach, Aziz Baydada
{"title":"Placenta Percreta with Bladder Invasion: Case Report","authors":"Mariam Mahtate, A. Slaoui, Soukaina Cherradi, N. Zeraidi, A. Lakhdar, A. Kharbach, Aziz Baydada","doi":"10.59657/2837-8172.brs.23.003","DOIUrl":"https://doi.org/10.59657/2837-8172.brs.23.003","url":null,"abstract":"Background: Placenta previa with bladder invasion is an uncommon and serious pathology, involving the maternal prognosis. However, as the rate of cesareans has increased, the disease has become more common. Case presentation: We present the case of placenta previa percreta in 34 weeks of amenorrhea, gravida 2 para 1, with a history of a single caesarean section 5 years prior. Initially admitted for threat of premature delivery, we found a totally covering placenta previa with accretization sign and suspicion of bladder invasion. Abdomino pelvic MRI confirmed the diagnosis of placenta previa percreta. During monitoring, the patient presented an acute fetal distress requiring an emergency fetal extraction. She underwent a caesarean section for fetal rescue followed by a total hysterectomy requiring the removing of the anterior part of the bladder. Conclusion: With a rising rate of cesarean sections, the risk of placenta accreta spectrum is increasing as well. Obstetricians and clinicians should be vigilant in prenatal diagnosis, especially if the risk factors are present. Multidisciplinary approach for preoperative, intraoperative and postoperative management can significantly improve maternal and fetal prognosis.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78283025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Badreldin Mohamed, S. Taha, L. Navaro, M. Cusso, T. Barakat, S. Babikir, D. Taran, C. Marson, T. Ojimba, D. Mirghani, S. Naqvi, R. Eifell
{"title":"Clinical Presentation and Management of Primary Mycotic Aortic Aneurysms: A Single Center Experience and Review of the Literature","authors":"Badreldin Mohamed, S. Taha, L. Navaro, M. Cusso, T. Barakat, S. Babikir, D. Taran, C. Marson, T. Ojimba, D. Mirghani, S. Naqvi, R. Eifell","doi":"10.59657/2837-8172.brs.23.005","DOIUrl":"https://doi.org/10.59657/2837-8172.brs.23.005","url":null,"abstract":"Background: Primary mycotic aortic aneurysm (PMAA) is a localized dilation of the aortic wall caused by direct spread of bacteria via the bloodstream to the aortic wall and subsequent development of an aneurysm. The term mycotic aortic aneurysm was first used to describe a patient with four aortic aneurysms which have a mushroom-like appearance, and the term has since been used. Aim: To conduct a literature review and to report a series of cases of infra-renal mycotic aortic aneurysms, their presentation and subsequent outcome and management. Methods: Information was gathered retrospectively from medical records for patients who were over the age of 18 and who had presented with PMAAs at Cumberland infirmary o from April 2016 to July 2022. Results: A total of six patients were assessed in our study, mean age was 57-88 years. Presenting complains were: Back pain (n=2), abdominal pain (n=1), fever (n=4), collapsed (n=2), confusion (n=1) and other clinical presentations were leg pain, feeling unwell and malaise each reported in one patient each. Potential risk factors for PMAA identified were malignancy (n=2), diabetes mellitus (n=2), chronic kidney disease (n=2), immunosuppressive medication (n=2) and alcohol misuse (n=1). Potential sources of infection were retroperitoneal inflammation (n=1), pyelonephritis (n=1), retroperitoneal /psoas infection (n=2), duodenitis (n=1), systemic sepsis (n=1). Management can be surgical intervention such as Endovascular aortic repair (EVAR) (n=2), or axillo-bifemoral bypass (n=2) all of them had post-operative antibiotics or only antibiotics (n=3), however two patients of them died. Conclusion: PMAAs are rare but they have high risk of morbidity and mortality. The diagnosis is challenging but CT A-abdomen and pelvis remains valuable for diagnosis. Surgery, either bypass or EVAR with antibiotics, is a cornerstone for management, however other alternatives can be considered.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90385759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epilepsy and dementia, a bidirectional relationship?","authors":"Roukya Benkhadra, Sophie Dupont","doi":"10.5455/ijmrcr.172-1652269967","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1652269967","url":null,"abstract":"Introduction: Epilepsy is one of the most common brain conditions, which affects over 70 million people worldwide, with a higher risk for people over the age of 70. In the other hand, dementia prevalence is up to 7% of individuals above the age of 65 years, and concerns 55 million people worldwide. Several studies were conducted to pursue causal relationship or bidirectional connection between those two pathologies and one of the latest systemic reviews gathering a numerous studies about this subject was published in 2017. By reviewing the most relevant articles in the literature we aimed to clarify the interconnection between epilepsy and dementia: coincidence due to the highest incidence in the elderly, or bidirectional relationship? We also focused our research on the newest studies about the possible impact of anti-epileptic drugs to improve dementia and vice versa. Methods: Due to the large numbers of articles about epilepsy and dementia, we collected twenty-three studies and reviews from 2014 to 2021 that focused on the relationship between those two pathologies, also some latest publications, especially epidemiological ones, concerning epilepsy and dementia. Results: Dementia is a heterogeneous syndrome that can be caused by numerous neurological and medical conditions. Epilepsy is more frequent in the elderly and is significantly higher in elderly patients with dementia than in elderly patients without dementia, whatever the type of dementia (AD, Lewy Body dementia, FTD,…). Numerous studies show that the high incidence of both diseases is not a coincidence of ageing and shared risk factors (i.e cerebrovascular events) and that the two diseases share common pathophysiological mechanisms. In the future, antiseizure approaches would complement and potentially enhance other strategies for treating AD, including that targeting disease protein aggregation.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73509984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anurag Dubey, Shivendra Tiwari, P. Patel, Avinash P. S. Thakur
{"title":"USING THE MODIFIED CLAVIEN GARDING SYSTEM TO CLASSIFY COMPLICATIONS OF BIPOLAR TURP","authors":"Anurag Dubey, Shivendra Tiwari, P. Patel, Avinash P. S. Thakur","doi":"10.5455/ijmrcr.172-1664801097","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1664801097","url":null,"abstract":"introduction: TURP is considered gold standard treatment for BPH. TURP was first introduced in 1929 by Maximilian Stern. Complications in TURP are less but not absolute. Modified Clavien Dindo Grading System is well-established classification for post-operative complications. Objective of this study is to assess complications of BIPOLAR TURP by using the modified Clavien grading system. Objective: To assess the evaluation of complications after bipolar transurethral resection of prostate using the Modified Clavien grading system. Materials And Methods: 110 BIPOLAR TURP performed between April 2019 and March 2021 at Meenakshi mission hospital Madurai Tamilnadu India were reviewed retrospectively. All patients with various complications were graded using Modified Clavien grading system in 5 grades. Results: 110 cases were enrolled in our study out of them 21 (19.9%) patients developed complications there was no mortality. Out of 21; 11 (52.4%) grade I, 5 (23.8%) grade II, 2 (9.5%) grade IIIa, 1 ( 4.8%) grade IIIb, 1 (4.8%) in each grade IVa and IVb. Conclusion: Modified Clavien Grading System is an easy and feasible classification system for postoperative complications. In spite of various shortcomings, it is very useful to grade end-urological procedure BIPOLAR TURP short-term complications.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74710551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Jose, D. Kale, Deepesh Chhablani, No author No author, D. Ingale, Dr.Chandrashekar Gore, D. Kumar
{"title":"Recent Trends And Seroprevalence Of Transfusion Transmitted Diseases Among Blood Donors In Western India","authors":"D. Jose, D. Kale, Deepesh Chhablani, No author No author, D. Ingale, Dr.Chandrashekar Gore, D. Kumar","doi":"10.5455/ijmrcr.172-1662094058","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1662094058","url":null,"abstract":"Abstract Introduction: Assessments of Transfusion Transmitted Diseases (TTDs) are essential for evaluating the safety of blood transfusion as well as monitoring the efficacy of current screening procedures. It also helps in formulating lifelong planning to upgrade our public health and to stop the spread of TTDs in general public. Materials and Methods: Our objective was to find out the recent trends and seroprevalence of TTDs in voluntary blood donors at a tertiary care hospital in western part of India. A total 4117 donors are included in our study from January to December 2019. The blood samples were tested for Human Immunodeficiency Virus I and II, Hepatitis B and C virus, Syphilis and Malaria. Results: Out of 4117 donors, a total of 39 (0.95 %) donors were positive for Transfusion Transmitted Diseases, out of which 23 (0.56%), 7(0.17%) and 9 (0.22%) donors were positive for HBV, HIV and HCV respectively. Conclusion: The most substantial part of every blood donation is finding out accurate blood donors who are at very low risk for Transfusion Transmitted Diseases and is achieved through efficient counseling and inclusion of more sophisticated techniques for screening to reduce the transmission during the window period. Key words : Transfusion Transmitted Diseases, blood donors, seroprevalence, Window period","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80498792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swati Das, A. Saxena, G. Chilkoti, Anshul Singh, Sargam Goel
{"title":"Evaluating the efficacy of combination therapy of Pregabalin plus Nortriptyline in the management of PHN patients: A randomized controlled study","authors":"Swati Das, A. Saxena, G. Chilkoti, Anshul Singh, Sargam Goel","doi":"10.5455/ijmrcr.172-1669175453","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1669175453","url":null,"abstract":"Background: Post Herpetic Neuralgia (PHN) is chronic neuropathic pain. It is a complication of herpes zoster and negatively impacts the patient’s quality of life and physical, occupational, social and psychosocial abilities due to unceasing pain. As pain management remains the cornerstone in treating such patients, this study was undertaken to determine the efficacy of fixed-dose combination therapy of Pregabalin plus Nortriptyline in PHN. Methods: The study, which was a follow-up, randomised, single-blind, controlled study, included a total of 40 patients who had chronic pain for at least 12 weeks with a Numeric rating scale (NRS) score of 5/10 or above. Group A (n=20) received pregabalin 75 mg plus nortriptyline 10 mg, and group B (n=20) received pregabalin 75 mg for a total of 12 weeks. Pain intensity and severity (using NRS and Global Perceived Effect), pain interference with sleep (using Numeric Rating Scale-Sleep (NRS-Sleep) and Pain Detect Questionnaire (PDQ)), pain quality (using Neuropathic Pain Symptom Inventory (NPSI)), and quality of life (QoL) (using Short Form-12 (SF-12) questionnaire) at the end of the first, second, fourth, eighth and twelfth week were measured. Results: Significant (p <0.05) decline in Numeric rating scale (NRS) scores, NRS sleep and NPSI scores in group A along with significant (p <0.05) improvement in PDQ, GPE and QoL scores, when compared to group B. Conclusion: The combination of pregabalin plus nortriptyline therapy has better patient outcomes in PHN as compared to pregabalin monotherapy.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79441601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DOUBLE EDGED SWORD- MUCORMYCOIS IN COVID 19 PATIENTS","authors":"Prathyusha Thummalagunta, Pragna Kakera, Lokabhinay Naidu","doi":"10.5455/ijmrcr.172-1671011456","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1671011456","url":null,"abstract":"INTRODUCTION : There is an increasing risk of mucormycosis in the post Covid patients , especially in the second wave of the pandemic, there has been a tremendous rise of mucormycosis in covid 19 cases, therby increasing the mortality and morbidity. There are many risk factors contributing to mucor among which diabetes mellitus is seen as an independant and most common risk factor. AIMS AND OBJECTIVES : To study the clinical manifestations, treatment ,mortality and mortality of mucormycosis in covid 19 . MATERIALS AND METHODS : This is an observational study carried out between April 2021 to june 2021. This study observes the clinical manifestations and CT findings ,treatment and outcomes in 25 patients of mucormycosis. OBSERVATION : This study included a total 25 patients of which 21(84%) are male and 4(16%) are female. The age of the patients varied between 25 -60 years with 49 years being the mean age group. Out of 25 members ,20 have diabetes, 1 has hypertension, 3 have hypothyroidism, 6 are smokers, 2 have coronary artery disease and are alcoholics. 24 underwent FESS & debridement and were treated with Amphotericin B and posaconazole. And 23 out of 25 used steroids. 2 of the 25 members died of severe mucor out of which 1 died before surgery and 1 after surgery CONCLUSION : In this study it has been observed that the early diagnosis and treatment of mucormycosis with better control of diabetes leads to improvement of mortality and morbidity in these patients.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81128082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}