双刃剑——covid - 19患者中的毛霉菌

Prathyusha Thummalagunta, Pragna Kakera, Lokabhinay Naidu
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摘要

摘要:新冠肺炎后患者发生毛霉菌病的风险不断增加,特别是在第二波大流行中,新冠肺炎患者的毛霉菌病发病率大幅上升,从而增加了死亡率和发病率。引起毛霉的危险因素很多,其中糖尿病被认为是一个独立的、最常见的危险因素。目的和目的:研究2019冠状病毒病毛霉病的临床表现、治疗、死亡率和死亡率。材料和方法:这是一项观察性研究,于2021年4月至2021年6月进行。本文对25例毛霉病的临床表现、CT表现、治疗及预后进行了观察。观察:本研究共纳入25例患者,其中男性21例(84%),女性4例(16%)。患者年龄在25 -60岁之间,平均年龄49岁。在25名成员中,20人患有糖尿病,1人患有高血压,3人患有甲状腺功能减退症,6人吸烟,2人患有冠状动脉疾病和酗酒。24例行FESS和清创,并用两性霉素B和泊沙康唑治疗。25人中有23人使用类固醇。25例患者中2例死于严重毛霉病,其中1例死于术前,1例死于术后。结论:本研究发现,对毛霉病进行早期诊断和治疗,并对糖尿病进行较好的控制,可降低毛霉病患者的死亡率和发病率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
DOUBLE EDGED SWORD- MUCORMYCOIS IN COVID 19 PATIENTS
INTRODUCTION : There is an increasing risk of mucormycosis in the post Covid patients , especially in the second wave of the pandemic, there has been a tremendous rise of mucormycosis in covid 19 cases, therby increasing the mortality and morbidity. There are many risk factors contributing to mucor among which diabetes mellitus is seen as an independant and most common risk factor. AIMS AND OBJECTIVES : To study the clinical manifestations, treatment ,mortality and mortality of mucormycosis in covid 19 . MATERIALS AND METHODS : This is an observational study carried out between April 2021 to june 2021. This study observes the clinical manifestations and CT findings ,treatment and outcomes in 25 patients of mucormycosis. OBSERVATION : This study included a total 25 patients of which 21(84%) are male and 4(16%) are female. The age of the patients varied between 25 -60 years with 49 years being the mean age group. Out of 25 members ,20 have diabetes, 1 has hypertension, 3 have hypothyroidism, 6 are smokers, 2 have coronary artery disease and are alcoholics. 24 underwent FESS & debridement and were treated with Amphotericin B and posaconazole. And 23 out of 25 used steroids. 2 of the 25 members died of severe mucor out of which 1 died before surgery and 1 after surgery CONCLUSION : In this study it has been observed that the early diagnosis and treatment of mucormycosis with better control of diabetes leads to improvement of mortality and morbidity in these patients.
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