D. Dhakad, Dr.Prabha S. Rastogi, D. Mathur, D. Niranjan
{"title":"A study of sexual satisfaction in spouse of male patients diagnosed with Schizophrenia.","authors":"D. Dhakad, Dr.Prabha S. Rastogi, D. Mathur, D. Niranjan","doi":"10.5455/ijmrcr.172-1682355544","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1682355544","url":null,"abstract":"<jats:p />","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85881041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Bat Child","authors":"M. Novo, M. Gaia, H. Santos, Mafalda Santos","doi":"10.5455/ijmrcr.172-1672847231","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1672847231","url":null,"abstract":"Case Report A short stature 10 year old boy with pes planus, mild hearing loss, failure of exfoliation of the primary dentition, anterior hyperdontia, malocclusion and open anterior fontanelle was observed in Pediatric Orthopedics consultation, and presenting the following alterations (image). Discussion This child has cleidocranial dysplasia (CCD). Is an autosomal dominant disease caused by an heterozygous loss-of-function mutation in the RUNX2 gene, encoding transcription factor CBFA1, on chromosome 6p21, which plays an important role in osteogenesis and differentiation of osteoblasts. The main clinical features include persistently open skull sutures, hypoplasia or aplasia of the clavicles permitting abnormal facility in opposing the shoulders, short middle phalanx of the fifth fingers, dental anomalies (supernumerary teeth, failure of exfoliation of the primary dentition and malocclusion), pes planus, upper respiratory complications, recurrent otitis media, hearing loss and often vertebral malformation (scoliosis). Conclusion The clinical diagnosis of CCD was made during pregnancy, through the detection of aplasia of the clavicles in fetu, in association with the mother having short stature (1.32 meters), persistence of primary teeth and open anterior fontanelle. With 10 years of age, he underwent mendilioma study which revealed the mutation in the RUNX2 gene (c. 747 del (p.(Arg251 Alafs*7))) classified as a pathogenic variant.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87154628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Júnior, C. Purnamasidhi, G. Purnama, R. Suteja, I. Adiputra, Jerry Jerry, I. Weisnawa, P. Wulandari, D. Shanti, I. Diksha
{"title":"MYOCARDITIS AS A PREVALENT CARDIOVASCULAR COMPLICATION IN OMICRON PATIENTS","authors":"D. Júnior, C. Purnamasidhi, G. Purnama, R. Suteja, I. Adiputra, Jerry Jerry, I. Weisnawa, P. Wulandari, D. Shanti, I. Diksha","doi":"10.5455/ijmrcr.172-1672835540","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1672835540","url":null,"abstract":"Ever since the first outbreak of SARS-CoV-2 in late December 2019 in China, it has undergone a significant number of mutations and manifested itself in different variants worldwide. One of the latest variants, namely the Omicron variant has proved to possess novel characteristics including a shift in its entry pathway. Studies have shown that the Omicron variant has adapted to enter host tissue more efficiently through endosomal pathway rather than cell fusion as shown in its predecessors. As far as coronaviruses are concerned, there are several modes of entry for endosomal pathway including the caveolae formation pathway which is mediated by proteins called caveolins. One of the caveolins in particular is found abundantly in cardiomyocytes, thus posing as a higher risk for the Omicron variant to directly invade the heart tissue.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81117077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the Long-Term Exposure to Low Doses of Ionizing Radiation on Catheterization Process Workers","authors":"Haliz Hussein, K. Abdullah, Asaad Asady","doi":"10.5455/ijmrcr.172-1659260804","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1659260804","url":null,"abstract":"Background: Workers in cardiac catheterization centers that employ X-rays may be exposed to low quantities of ionizing radiation for long periods of time, causing damage to human cells and tissues. Blood cell composition testing is an important monitoring technique in the typical diagnostic examination. Objectives: The present study has been designed to evaluate Ionizing radiation's impact on the hematological parameters of occupational exposure in a cardiac catheterization lab at Azadi teaching hospital in Duhok city of Iraq. Methods: The study involved 40 hospital employees working in medical radiation centers who have been exposed to lower doses of ionizing radiation during Radiotherapy or diagnostic and the 32 unexposed workers as control. The correlation between the total dose and the hematological indices of exposed workers is examined using a bivariate regression analysis program. Results: The results looked to be significantly different with (p<0.05) compared to the respective controls in all blood parameters. Nevertheless, there is no significant difference (p>0.05) in Mean corpuscular volume, Mean Corpuscular Hemoglobin, Mean Corpuscular Hemoglobin Concentration, White blood cells, and Lymphocytes values obtained as compared with the control. Conclusions: The study found that almost some hematological parameters are affected by radiation. Further research should incorporate a variety of other independent factors such as (chromosomal aberrations and genetic polymorphisms) to study further low-dose radiation's long-term effects on personnel who were exposed to it.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81335012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychotherapy-Resistant Posttraumatic Stress Disorder \u0000Could Methylphenidate be a Solution?\u0000Case Report 1","authors":"K. Farha","doi":"10.5455/ijmrcr.172-1686509625","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1686509625","url":null,"abstract":"Introduction Chronic hypoarousal and hyperarousal states are 2 key features for the diagnosis of post-traumatic stress disorder (PTSD). They represent an out of tolerance window zones and can negatively affect receiving, processing, and integration of stimuli. They are debilitating clusters of symptoms that reduce quality of life and significantly interfere with the individual’s daily functioning. Moreover, chronic significant hyperarousal- hypoarousal shifts can interfere with patient’s engagement in psychotherapy. Addressing these out of tolerance window states may reduce patient’s distress and improve his/ her quality of life and psychotherapy outcome. Case presentation This report describes a clinical case of psychotherapy- resistant PTSD key symptoms in a 32-year-old female patient. Stand-alone psychotherapy in the form of Eye Movement Desensitization and Reprocessing (EMDR) failed to lessen the PTSD symptoms. Persistence of PTSD hypo- and hyper-arousal symptoms significantly interfered with the patient’s daily functions and limited the progress and effectiveness psychotherapy. Given the nature and severity of her illness, the patient had been reassessed. Re-assessment included a clinical interview, blood tests, vital signs, ECG, anthropometric characteristics, assessment for attention deficit hyperactivity disorder (ADHD) and borderline personality disorder (BPD). Diagnosis of comorbid ADHD has been confirmed and the patient has been commenced on methylphenidate (MPH) with adjunct propranolol for associated paroxysmal sinus tachycardia. The effect and side effects of the treatment were monitored during a follow-up period of 7 weeks. Main parameters assessed were flashbacks, nightmares, dissociation and fainting, and hypervigilance with paranoid symptoms. Within one week of commencing the treatment the patient reported improvement in all psychotherapy- resistant PTSD symptoms. Remission of symptoms remained until the last follow up review (7 weeks post-treatment). Conclusion PTSD- related hypoarousal and hyperarousal symptoms reduce patient’s quality of life, impair his/her daily functioning, and could hinder the effective progress of psychotherapy, a corner stone in the treatment of PTSD. Pre-psychotherapy diagnosis and treatment of PTSD comorbidities such as ADHD may decrease PTSD symptoms severity. MPH seems to play a clinically meaningful role in the treatment of PTSD-related hyperarousal- hypoarousal symptoms and thereby reduces patient distress and improves patient’s quality of life and may facilitate successful psychotherapy outcome.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82618051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}