International Journal of Medical Reviews and Case Reports最新文献

{"title":"NEONATAL GROUP B STREPTOCOCCAL DISEASE IN A NEONATAL INTENSIVE CARE UNIT: A TWELVE-YEAR STUDY","authors":"","doi":"10.5455/ijmrcr.172-1673802395","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1673802395","url":null,"abstract":"Introduction: Group B Streptococcus (GBS) is a gram-positive coccus, that frequently colonizes the human genital and gastrointestinal tract, and is the most common cause of invasive infections in neonates. The high clinical suspicion and early treatment are essential to prevent devastating sequelae and improve the prognosis of these patients. Materials and Methods: A retrospective descriptive study made with children younger than 3 months of age, admitted to a neonatal intensive care unit of a level II hospital, from January 1, 2010 to December 31, 2021, with early (EOI) or late-onset (LOI) neonatal GBS infection. Reviewed obstetric history, risk factors, intrapartum chemoprophylaxis (IPA), clinical manifestations, antibiotic therapy, supportive care, recurrent infection, morbidities and deaths. Results: There were 6 cases registered during 12-year period with GBS infection, 3(50%) had EOI, 3(50%) had LOI and 1 case with recurrent infection (more 2 episodes). Most cases were prematures (4/6; 67%)with average gestational age of 29weeks. Eight GBS infections were documented. In EOI, prematurity and prolonged rupture of membranes without chemoprophylaxis were identified as risk factors. The most common clinical diagnosis was meningitis (62,5%, 5/8) and sepsis/bacteriemia without a focus (37,5%, 3/8). The most used empirical therapy was ampicillin, gentamicin and cefotaxime (50%, 4/8) and the most frequent definitive therapy was Penicillin G. 4 patients needed ventilatory support and 1 needed shock and seizures treatment. In one case hydrocephalus and delayed psychomotor development (DPD) were reported and in another case DPD and eyelid ptosis were also reported. 1 death occurred. Conclusion: In our study, maternal colonization wasn’t a risk factor for EIO, because the 4 mothers who performed GBS culture (2 mothers of term newborns and 2 mothers of preterms, one with invasive disease and other with recurrent infection) were negative. We obtained a higher percentage of meningitis than previously described (62.5% vs 5-10%), probably because most patients were premature and immunosuppressed.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88191518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CONVENTIONAL CYTOLOGY VERSUS LIQUID BASED CYTOLOGY FOR EVALUATION OF CERVICAL SMEARS – A STUDY OF 300 CASES","authors":"Rupali R. Bavikar, Meesha Zaheer, A. Buch, Rajeshwari Raishankar, R. Khan, C. Gore","doi":"10.5455/ijmrcr.172-1650453121","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1650453121","url":null,"abstract":"BACKGROUND: Over the years, different studies conducted have established the advantages of liquid based cytology(LBC) over conventional preparations(CP) in cervical smears screening. However, the high cost of machinery required for the preparations still limits its usage in low-resource countries. This study aims to evaluate the performance of a low cost LBC method, EziPREP™ technique against conventional preparations for cervical screening. MATERIALS & METHOD: This was a cross sectional study comprising of 300 consequtive cervical samples over a period of 2 year. CP smears were prepared as per the standard technique using ayre’s spatula while for LBC sample was obtained on endocervical brush followed by detaching the head of brush into the fixative vials of LBC. The LBC samples were processed as per the manufacturer's protocol. Both CP and LBC smears were stained using standard Papanicolaou stain & H & E stain protocol. Slides were analysed by two pathologists independently. RESULTS: The unsatisfactory rate for CP was 5%, main cause being obscuring haemorrhage and inflammation, whereas on LBC samples it was 1.4%, owing to inadequate cellular material. Uniform distribution was more in LBC smears, with minimal overlapping. The morphological details were comparable in both sets of smears. The pathogenic organisms, like Gardenella(31%) & Candida(20%) were detected in more CP smears, Trichomonas was seen equally in both smears(3%). There was a 98% concordance in cytologic diagnosis between CP and LBC smears. Screening time was notably reduced in LBC smears (3±1minutes vs 5±1 minutes for CP) CONCLUSION: This low-cost LBC method holds promise in providing monolayered cervical smears with a clear background. It might carve the way for inclusion of liquid based cytology methods for cervical cancer screening on a larger scale in the low resourse countries.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83851382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception And Acceptability Of COVID-19 Vaccine Among Medical Students Of a Tertiary Care Hospital: A Cross-sectional Study","authors":"Bharati Panda, S. Satapathy, Arati Panda, R. Dash","doi":"10.5455/ijmrcr.172-1678962299","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1678962299","url":null,"abstract":"Background- Coronavirus disease (Covid-19) caused by SARS-CoV-2 has affected more than 200 countries, creating havoc throughout the world. The accelerated development of the Covid-19 vaccine is thus vital development which created a milestone in the field of health. Vaccine hesitancy among the medical students and professionals might be a significant obstacles in implementing the vaccination drive programme. Objectives: 1) To assess the perception of medical students regarding COVID-19 vaccine. 2) To estimate the acceptability of COVID-19 vaccine among medical students of VIMSAR, Burla. 3) To determine the association of various factors with the perceptions and acceptability of COVID-19.Methodology: It was a cross-sectional study conducted for a period of 3months i.e August-October 2022 among the MBBS students of VIMSAR, Burla. The total sample size was 847. Results: 99.4%. of the students accepted Covid-19 as a fatal disease & almost all of the students had heard and know about COVID-19 vaccine but 93.3% among them think the vaccine will prevent the disease and build the immunity but 77.4% accept the vaccine to be safe and effective. Social media(94.3%) and news channel(94.6%) were the most common source of information for them. Covid-19 vaccine was taken by 728(86%) of students. Regarding the adverse events following immunisation only 34.4% of the students have heard it.. The 1st year batch students had least perception & acceptability on COVID-19 vaccine whereas maximum was seen among the final year students . The association between the various batches of MBBS students with the perception & acceptability on COVID-19 was found to be significant with chi-square value 123.4981 & 109.1895 respectively with P=0.001.Conclusion- Even though perception and acceptability about COVID-19 vaccine among the students is good but regarding the adverse events following immunisation many are unaware and are having lots of apprehension which could be dealt with proper sensitisation meetings.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"155 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88252825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the 2020 COVID-19 Confinement on obese and overweight children in a Portuguese Hospital Setting","authors":"B. Mota, M. Carvalho, Andreia Teixeira, F. Cunha, N. Brito","doi":"10.5455/ijmrcr.172-1665736819","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1665736819","url":null,"abstract":"<jats:p />","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85357821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frictional Lichenoid Dermatitis","authors":"Marta Caldas, M. Pedro, A. Morais, A. Bicho","doi":"10.5455/ijmrcr.172-1658980314","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1658980314","url":null,"abstract":"A previously healthy 4-year-old boy presented with a rash on his elbows and knees that over 3 weeks became pruritic and expanded to the posterior cervical region and hands. It appeared during the summer, while frequently wearing a thermal suit. The patient had no systemic symptoms and none of his cohabitants had a rash. Skin examination revealed flesh-colored to mildly erythematous flat-topped papules on the extensor surfaces of the elbows and knees, posterior cervical region and the dorsum of the hands (Figure 1). The findings were compatible with the diagnosis of frictional lichenoid dermatitis, no further studies were performed and the patient was treated with topical hydrocortisone during 2 weeks, with improvement. Frictional lichenoid dermatitis is probably underdiagnosed and it is a benign and self-limited disease with typical clinical presentation, so it is important to recognize it as not to prescribe unnecessary workup and medication.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"31 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84170702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Misdiagnosed Solitary Nodule with Rapid Progression to Invasive Ductal Carcinoma","authors":"Kevan English","doi":"10.5455/ijmrcr.172-1687449007","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1687449007","url":null,"abstract":"<jats:p>None.</jats:p>","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73253445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anosmia in an adolescent: what to suspect?","authors":"Adriana Ferreira, Sofia Pimenta, E. Sousa, ngela Machado","doi":"10.5455/ijmrcr.172-1665326071","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1665326071","url":null,"abstract":"Anosmia is an uncommon complaint in children and adolescents and it is usually acquired. Congenital anosmia is usually associated with Kallmann’s Syndrome, but, rarely, can present with olfactory bulb agenesis as an isolated finding. We present a case of a 15-year-old boy with olfactory bulb agenesis without other structural abnormalities and hormonal deficiencies in whom the diagnosis of isolated congenital anosmia was made. We also briefly review the possible causes of anosmia, the recommended diagnostic workup, and management.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79882989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Bat Child","authors":"M. Novo, M. Gaia, H. Santos, Mafalda Santos","doi":"10.5455/ijmrcr.172-1672847231","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1672847231","url":null,"abstract":"Case Report A short stature 10 year old boy with pes planus, mild hearing loss, failure of exfoliation of the primary dentition, anterior hyperdontia, malocclusion and open anterior fontanelle was observed in Pediatric Orthopedics consultation, and presenting the following alterations (image). Discussion This child has cleidocranial dysplasia (CCD). Is an autosomal dominant disease caused by an heterozygous loss-of-function mutation in the RUNX2 gene, encoding transcription factor CBFA1, on chromosome 6p21, which plays an important role in osteogenesis and differentiation of osteoblasts. The main clinical features include persistently open skull sutures, hypoplasia or aplasia of the clavicles permitting abnormal facility in opposing the shoulders, short middle phalanx of the fifth fingers, dental anomalies (supernumerary teeth, failure of exfoliation of the primary dentition and malocclusion), pes planus, upper respiratory complications, recurrent otitis media, hearing loss and often vertebral malformation (scoliosis). Conclusion The clinical diagnosis of CCD was made during pregnancy, through the detection of aplasia of the clavicles in fetu, in association with the mother having short stature (1.32 meters), persistence of primary teeth and open anterior fontanelle. With 10 years of age, he underwent mendilioma study which revealed the mutation in the RUNX2 gene (c. 747 del (p.(Arg251 Alafs*7))) classified as a pathogenic variant.","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87154628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIABETES MELLITUS AND CONCURRENT RENAL INSUFFICIENCY AS PROGNOSTIC INDICATORS FOR ACUTE MYOCARDIAL INFARCTION","authors":"Rajeev Kumar","doi":"10.5455/ijmrcr.172-1678017905","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1678017905","url":null,"abstract":"<jats:p />","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87760240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study of sexual satisfaction in spouse of male patients diagnosed with Schizophrenia.","authors":"D. Dhakad, Dr.Prabha S. Rastogi, D. Mathur, D. Niranjan","doi":"10.5455/ijmrcr.172-1682355544","DOIUrl":"https://doi.org/10.5455/ijmrcr.172-1682355544","url":null,"abstract":"<jats:p />","PeriodicalId":13694,"journal":{"name":"International Journal of Medical Reviews and Case Reports","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85881041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}