Infection最新文献_第5页

Correction: A simple scoring algorithm predicting paravertebral and/or Iliopsoas abscess among adults with community-onset bloodstream infections: matters of PVL-producing staphylococcus aureus. 更正：一种简单的评分算法预测社区发病血液感染的成人椎旁和/或髂腰肌脓肿：产pvl金黄色葡萄球菌的问题。

IF 5.4 2区医学

Infection Pub Date : 2025-03-25 DOI: 10.1007/s15010-025-02510-2

Ching-Chi Lee, Ching-Yu Ho, Ming-Yuan Hong, Yuan-Pin Hung, Wen-Chien Ko

引用次数: 0

Corynebacterium rouxii in a free-roaming red fox: case report and historical review on diphtheria in animals. 自由活动的红狐中的鲁氏棒状杆菌：动物白喉病例报告和历史回顾。

IF 5.4 2区医学

Infection Pub Date : 2025-03-25 DOI: 10.1007/s15010-025-02515-x

Andreas Sing, Alexandra Dangel, Regina Konrad, Dominik M Meinel, Ingo Schwabe, Reinhard Sting, Jörg Rau, Anja Berger

引用次数: 0

Periorbital primary cutaneous mucormycosis: a case report and literature review. 眼眶周围原发性皮肤毛霉病1例报告并文献复习。

IF 5.4 2区医学

Infection Pub Date : 2025-03-25 DOI: 10.1007/s15010-024-02464-x

Yan Xu, Chunyou Wang, Lian Zhang, Zhifang Zhai, Huan Wang

引用次数: 0

Trichomonas vaginalis in neonates. 新生儿阴道毛滴虫。

IF 5.4 2区医学

Infection Pub Date : 2025-03-25 DOI: 10.1007/s15010-025-02508-w

Herbert Hof, K A Bode, H Weisser

{"title":"Trichomonas vaginalis in neonates.","authors":"Herbert Hof, K A Bode, H Weisser","doi":"10.1007/s15010-025-02508-w","DOIUrl":"https://doi.org/10.1007/s15010-025-02508-w","url":null,"abstract":"Background: Trichomonas vaginalis is one of the most prevalent pathogens responsible for non-viral sexually transmitted infections. The infection mainly affects women of childbearing age, with the potential for complications during and after pregnancy. Although perinatal transmission is rare, it carries the risk of resulting in neonatal infections. To date, only a dozen documented cases have been reported in the scientific literature. Since modern PCR techniques is more sensitive than conventional methods, it can be anticipated that this microbe will be detected more frequently, even in newborns.Case presentation: The present report describes the clinical courses of two neonates contaminated with T. vaginalis documented by multiplex PCR. The pathogens were detected in newborns without obvious clinical suspicion of sexually transmitted infections.Conclusion: T.vaginalis can be transmitted from an infected mother to her child during vaginal delivery resulting either in transient colonization or in manifest disease. It is likely that in the future, when multiplex PCR becomes more widely apllied, sexually transmitted infections will be detected more frequently in neonates.","PeriodicalId":13600,"journal":{"name":"Infection","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of treatment of COVID-19 with sotrovimab on post-acute sequelae of COVID-19 (PASC): an analysis of National COVID Cohort Collaborative (N3C) data. sotrovimab治疗COVID-19对COVID-19急性后后遗症（PASC）的影响：国家COVID队列协作（N3C）数据分析

IF 5.4 2区医学

Infection Pub Date : 2025-03-22 DOI: 10.1007/s15010-025-02505-z

Myriam Drysdale, Rose Chang, Tracy Guo, Mei Sheng Duh, Jennifer Han, Helen Birch, Catherine Sharpe, Daisy Liu, Sarah Kalia, Melissa Van Dyke, Maral DerSarkissian, Iain A Gillespie

{"title":"Impact of treatment of COVID-19 with sotrovimab on post-acute sequelae of COVID-19 (PASC): an analysis of National COVID Cohort Collaborative (N3C) data.","authors":"Myriam Drysdale, Rose Chang, Tracy Guo, Mei Sheng Duh, Jennifer Han, Helen Birch, Catherine Sharpe, Daisy Liu, Sarah Kalia, Melissa Van Dyke, Maral DerSarkissian, Iain A Gillespie","doi":"10.1007/s15010-025-02505-z","DOIUrl":"https://doi.org/10.1007/s15010-025-02505-z","url":null,"abstract":"Purpose: To assess the impact of early sotrovimab treatment versus no treatment on the risk of developing post-acute sequelae of COVID-19 (PASC; long COVID) in patients (age ≥ 12 years) with COVID-19 at high risk for progression to severe disease.Methods: Retrospective cohort study using the US National COVID Cohort Collaborative (N3C) data. Phase 1 identified and assessed multiple definitions of PASC; Phase 2 evaluated the effectiveness of sotrovimab for reducing the risk of PASC, utilizing definitions from Phase 1. Average treatment effect in the treated (ATT)-weighted Cox proportional hazards regression models were used to compare time to event for PASC between high-risk patients who received sotrovimab treatment between May 26, 2021 and April 5, 2022, and high-risk patients with COVID-19 diagnosed between May 26, 2021 and March 26, 2022 who did not receive any treatment for COVID-19 during the acute phase or any pre-exposure prophylaxis against SARS-CoV-2.Results: A total of 9,504 sotrovimab-treated and 619,668 untreated patients were included in the main analysis. Most baseline characteristics were balanced between the two cohorts after ATT weighting. The doubly robust ATT-weighted hazard ratio (95% confidence interval) was 0.92 (0.89-0.96) (p < 0.001), indicating that sotrovimab use was associated with a significantly lower risk of PASC. Results remained consistent in sensitivity analyses.Conclusion: In patients at high risk for severe COVID-19, the benefits of early sotrovimab treatment may extend beyond the acute phase of COVID-19 and contribute to the prevention of PASC symptoms.","PeriodicalId":13600,"journal":{"name":"Infection","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kidney involvement in leptospirosis: a systematic review and meta-analysis. 钩端螺旋体病肾脏受累：一项系统回顾和荟萃分析。

IF 5.4 2区医学

Infection Pub Date : 2025-03-20 DOI: 10.1007/s15010-025-02492-1

Astha Sethi, Tirlangi Praveen Kumar, Kutty Sharada Vinod, Carl Boodman, Rachana Bhat, Prithvishree Ravindra, Souvik Chaudhuri, Seema Shetty, V Shashidhar, Attur Ravindra Prabhu, Nitin Gupta

{"title":"Kidney involvement in leptospirosis: a systematic review and meta-analysis.","authors":"Astha Sethi, Tirlangi Praveen Kumar, Kutty Sharada Vinod, Carl Boodman, Rachana Bhat, Prithvishree Ravindra, Souvik Chaudhuri, Seema Shetty, V Shashidhar, Attur Ravindra Prabhu, Nitin Gupta","doi":"10.1007/s15010-025-02492-1","DOIUrl":"https://doi.org/10.1007/s15010-025-02492-1","url":null,"abstract":"Introduction: From a public health perspective, it is essential to understand the burden of kidney involvement in leptospirosis. We aimed to assess the frequency of acute kidney injury (AKI) and chronic kidney disease (CKD) in patients with leptospirosis.Methodology: This systematic review and meta-analysis included all articles up to 14.08.2024 from three databases (PubMed, Scopus, Web of Science) using search terms related to leptospirosis and kidney involvement. After de-duplication, two independent reviewers independently checked the articles in two phases (title-abstract and full-text), and a third reviewer adjudicated any conflicts. Patient demographics, diagnostic procedures, and details of kidney involvement were extracted from the included studies. Risk of bias analysis was done using the Joanna Briggs Institute critical appraisal tool. A random effects model estimated the pooled rates for AKI, oliguria, and the need for dialysis.Results: Of the 5913 retrieved articles, 48 met the eligibility criteria. The pooled incidence of AKI, reduced urine output, and dialysis requirement was 49.2% (95%CI: 38.2-60.2%, I2 of 99.4%), 31.5% (95%CI: 24.2-38.7%, I2-96.1%) and 14.4% (95%CI: 10.3-18.4%, I2-97%) respectively. The pooled mean serum creatinine and urea levels at admission were 3.6 mg/dl (95% CI: 2.9-4.2, I2-99.1%) and 131.8 mg/dl (95% CI: 98.7-164.9, I2-98.6%), respectively. In four studies, the incidence of new-onset CKD after leptospirosis infection varied from 13 to 62%.Conclusion: AKI reduced urine output and the requirement for dialysis are frequent complications in patients with leptospirosis. Increased resources for their management in endemic areas are essential to mitigate the burden.","PeriodicalId":13600,"journal":{"name":"Infection","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: A practice already in use: a snapshot survey on the use of doxycycline as a preventive strategy (Doxy-PEP and Doxy-PrEP) in the GBMSM population in Spain. 更正：一个已经在使用的做法：对西班牙GBMSM人群使用强力霉素作为预防策略（Doxy-PEP和Doxy-PrEP）的快照调查。

IF 5.4 2区医学

Infection Pub Date : 2025-03-19 DOI: 10.1007/s15010-025-02514-y

Sergio Villanueva Baselga, Ruben Mora, Luis Villegas

引用次数: 0

The adverse impact of cytomegalovirus infection on intensive care units outcomes in critically ill COVID-19 patients: a single-center prospective observational study. 巨细胞病毒感染对COVID-19危重患者重症监护病房结局的不利影响：一项单中心前瞻性观察研究

IF 5.4 2区医学

Infection Pub Date : 2025-03-19 DOI: 10.1007/s15010-025-02499-8

Marina López-Olivencia, Raúl de Pablo, Noemí Paredes de Dios, Susana García-Plaza, Sergio Sáez-Noguero, Javier Sáez de la Fuente, Jesús Fortún, María Cruz Soriano Cuesta

{"title":"The adverse impact of cytomegalovirus infection on intensive care units outcomes in critically ill COVID-19 patients: a single-center prospective observational study.","authors":"Marina López-Olivencia, Raúl de Pablo, Noemí Paredes de Dios, Susana García-Plaza, Sergio Sáez-Noguero, Javier Sáez de la Fuente, Jesús Fortún, María Cruz Soriano Cuesta","doi":"10.1007/s15010-025-02499-8","DOIUrl":"https://doi.org/10.1007/s15010-025-02499-8","url":null,"abstract":"Purpose: To assess the incidence and clinical impact of CMV infection in critically ill COVID-19 patients, examining ICU and hospital mortality, and length of hospital stay.Methods: In this single-center, prospective observational study (March 2020 - September 2022), 431 patients with COVID-19 pneumonia and moderate to severe ARDS were included. An active CMV surveillance protocol was implemented, analyzing CMV DNA in plasma and bronchoalveolar lavage (BAL). Clinical characteristics and outcomes were compared between CMV-COVID co-infected patients and those without CMV reactivation.Results: CMV-COVID co-infection was detected in 14.8% (64/431) of the cohort. Patients with CMV-COVID co-infection exhibited significantly higher ICU mortality (43.8% vs. 13.6%; p < 0.001) and hospital mortality (48.4% vs. 13.6%; p < 0.001) compared to patients without CMV. CMV infection was an independent predictor of hospital mortality (OR 4.91; 95% CI 2.76-8.75; p = 0.019). Earlier CMV reactivation was associated with an increased risk of hospital mortality (HR = 0.94; 95% CI: 0.90-0.98; p = 0.003). Additionally, CMV-COVID patients had a higher incidence of ICU-acquired infections and a prolonged hospital stay.Conclusions: In critically ill patients with SARS-CoV-2 pneumonia, CMV infection was frequently observed, and associated with increased ICU and hospital mortality. CMV co-infection correlated with a higher incidence of ICU-acquired bacterial and fungal infections and prolonged hospital stays. This emphasizes the importance of early CMV monitoring upon ICU admission, as timely detection and intervention could potentially mitigate its impact on patient outcomes.","PeriodicalId":13600,"journal":{"name":"Infection","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Creative illustration for choosing-wisely recommendations on asymptomatic bacteriuria of the Network Young Infection Medicine e.V. - jUNITE. 网络青年感染医学e.v. - jUNITE对无症状菌血症的明智选择建议的创造性说明。

IF 5.4 2区医学

Infection Pub Date : 2025-03-19 DOI: 10.1007/s15010-024-02434-3

Kristin Heenemann, Sarah Kotsias-Konopelska, Jutta Pikalo, Sophie Schneitler, Viktoria Schneitler, Anna Schwabe

引用次数: 0

Publisher Correction: Evaluation of systemic inflammatory response following transcatheter aortic valve replacement: a pathway to rational antibiotic use. 经导管主动脉瓣置换术后全身炎症反应的评估：合理使用抗生素的途径。

IF 5.4 2区医学

Infection Pub Date : 2025-03-19 DOI: 10.1007/s15010-025-02511-1

Henning Guthoff, Valerie Lohner, Ute Mons, Julia Götz, Hendrik Wienemann, Jan Wrobel, Stephan Nienaber, Sascha Macherey-Meyer, Philipp von Stein, Stephan Baldus, Matti Adam, Maria Isabel Körber, Norma Jung, Victor Mauri

引用次数: 0