Innovation in Aging最新文献

{"title":"Effects of Somatosensory Games on Heart Rate Variability and Sleep-Related Biomarkers in Menopausal Women With Poor Sleep Quality.","authors":"Yi-Yuan Lin, Yi-Hung Liao, Hua Ting, Kunanya Masodsai, Chi Chen","doi":"10.1093/geroni/igae072","DOIUrl":"10.1093/geroni/igae072","url":null,"abstract":"<p><strong>Background and objectives: </strong>The aim of this study was to investigate the effects of 12-week somatosensory games on heart rate variability and sleep-related biomarkers in middle-aged women with poor sleep quality.</p><p><strong>Research design and methods: </strong>Twenty-nine women with poor sleep quality were recruited as participants randomly assigned into ring fit adventure exergame group (RFA, <i>n</i> = 15) and control group (CON, <i>n</i> = 14). The RFA group received ring fit adventure exergame for 60 min each time, 2 times a week, for 12 weeks. The CON group was not allowed to participate in intervention activities during the study period. Heart rate variability, sleep quality, cortisol, serotonin, and high-sensitive C-reactive protein were measured before and after the 12-week intervention.</p><p><strong>Results: </strong>The Pittsburgh Sleep Quality Index total score in the RFA group was significantly lower compared with the CON group. The value of the standard deviation of normal NN intervals and the root mean square of the successive RR Differences were significantly increased in the RFA group, when compared with the CON group. The change in the logarithm of high frequency (log HF) was significantly higher and change in the logarithm of low frequency to high frequency ratio (log LF/HF) was significantly lower in the RFA group, when compared to the CON group. The change level of serotonin in the RFA group was significantly higher compared with the CON group.</p><p><strong>Discussion and implications: </strong>The results suggest that somatosensory games might improve sleep quality, increase serotonin level, and decrease sympathetic nerve activities in middle-aged women with poor sleep quality.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 9","pages":"igae072"},"PeriodicalIF":4.9,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142345909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensional Care Poverty Among East Asian and Nordic Older Adults.","authors":"Yueh-Ching Chou, Jiby Mathew Puthenparambil, Teppo Kröger, Christy Pu","doi":"10.1093/geroni/igae076","DOIUrl":"10.1093/geroni/igae076","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study uses the care poverty framework, focusing on both individuals and structures. In this context, structures are represented by 2 welfare states: Taiwan, an East Asian welfare system and Finland, a Nordic welfare state. This study explores multidimensional care poverty rates and examines 3 realms of individual factors (health status, sociodemographic factors, and care support availability) among older adults in these long-term care (LTC) models.</p><p><strong>Research design and methods: </strong>We analyzed data from the 2019 Taiwan Longitudinal Study on Ageing Survey and the 2020 Daily Life and Care in Old Age Survey in Finland to compare the rates and factors of care poverty in these 2 culturally and structurally different countries.</p><p><strong>Results: </strong>Our analysis revealed different rates of care poverty in personal, practical, and socioemotional care needs in the 2 countries. Under a familistic welfare regime, Taiwanese older adults had higher personal care poverty rates than their Finnish counterparts. Those living alone faced more personal and practical care poverty. Conversely, Finnish older adults, under the Nordic welfare model, experienced more practical and socioemotional care poverty. Those with high care needs and disadvantaged social status and support were more likely to experience personal and practical care poverty. Socioemotional care poverty varied with the availability of support and health status in both countries.</p><p><strong>Discussion and implications: </strong>The study highlights the impact of 2 LTC policies and cultures on older adults' multidimensional care poverty, identifying disadvantaged older adults under different welfare-transforming LTC models. Taiwan's budget-constrained LTC policies and high family reliance contrast with Finland's inadequate attention to the practical and socioemotional needs of its aging population. This study suggests that holistic LTC policies are needed in both countries to improve the well-being of older adults with limited support and health issues.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 9","pages":"igae076"},"PeriodicalIF":4.9,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142345910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Soundscape Augmentation on Behavioral Symptoms in People With Dementia: A Pilot Randomized Controlled Trial.","authors":"Arezoo Talebzadeh, Dick Botteldooren, Pieter Thomas, Steven Stewart, Dominique Van de Velde, Patricia De Vriendt, Paul Devos, Andrea Iaboni","doi":"10.1093/geroni/igae069","DOIUrl":"10.1093/geroni/igae069","url":null,"abstract":"<p><strong>Background and objectives: </strong>Sound is an important environmental factor that influences the expression of behavioral and psychological symptoms of dementia. Recent research on the effect of soundscape has shown promising results in improving environmental impact on people with dementia. However, no controlled studies have aimed to quantify the effects of soundscape intervention on resident outcomes. The aim of this study was to assess the feasibility and impact of a soundscape intervention on people with dementia and behavioral symptoms.</p><p><strong>Research design and methods: </strong>Pilot single-blind repeated-measures randomized controlled trial of an augmented soundscape intervention. Participants were people with dementia in a hospital-based specialized dementia unit. Participants were randomized to an augmented soundscape intervention delivered in their room in the morning and evening or treatment as usual, with 2 baseline weeks and 4 weekly post-randomization assessments of the primary and secondary behavioral outcomes.</p><p><strong>Results: </strong>The soundscape intervention was feasible in terms of recruitment, retention, and delivery of the intervention. There were improvements in the neuropsychiatric inventory total scores over time in both groups (-5.89, 95%CI -8.45 to -3.28, <i>p</i> < .001), but no differences between groups. There were no significant group, time, or group × time differences for the Pittsburgh Agitation Scale (PAS) total score. For the PAS-resisting care subscale, there was a significant group × time difference, with a greater reduction in the soundscape group over the study period (-0.81, 95% CI -1.59 to -0.03, <i>p</i> = .042).</p><p><strong>Discussion and implications: </strong>In this pilot study, soundscape augmentation was a feasible and effective nonpharmacological approach to reducing resistance to care in people with dementia, although it did not improve neuropsychiatric symptoms more globally. Further studies with larger samples and of longer duration are needed to investigate the long-term effects of augmented sonic environments on people with dementia.</p><p><strong>Clinical trials registration number: </strong>NCT04809545.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 9","pages":"igae069"},"PeriodicalIF":4.9,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142345908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics of Older Adults Living in Foster Families in the French West Indies: Baseline Screening of the KArukera Study of Aging in Foster Families (KASAF) Cohort.","authors":"Denis Boucaud-Maitre, Roxane Villeneuve, Christine Rambhojan, Nadine Simo-Tabué, Nathalie Thibault, Leila Rinaldo, Jean-François Dartigues, Moustapha Dramé, Hélène Amieva, Maturin Tabué-Teguo","doi":"10.1093/geroni/igae063","DOIUrl":"10.1093/geroni/igae063","url":null,"abstract":"<p><strong>Background and objectives: </strong>Foster families for older adults could represent a transitional or alternative model to nursing homes. The aim of this study was to describe the clinical characteristics of older adults in foster families and to compare them with those of residents in nursing homes in French West Indies.</p><p><strong>Research design and methods: </strong>This study is a cross-sectional analysis of the KArukera Study of Aging in Foster Families (KASAF) cohort. Sociodemographic and clinical characteristics were extracted. Dependency was assessed using the Activities of Daily Living (ADL) scale and cognition using the Mini-Mental State Examination (MMSE) scale. Age, gender, ADL, and MMSE scores were compared with nursing home residents from a twin study of KASAF (<i>n</i> = 332).</p><p><strong>Results: </strong>A total of 107 older adults (mean age 81.8 years; 61.7% women) were recruited in 56 foster families between September 2020 and May 2021. In all, 25.5% had diabetes mellitus and 45.8% suffered from hypertension. The mean MMSE score was 9.3 ± 10.1 and 76.0% had major cognitive impairment (MMSE score <18); 12.5% were diagnosed with Parkinson's disease, and 42.0% of the residents were confined to bed or in a wheelchair, with a mean ADL score of 1.5 ± 1.8. Almost all the residents (96.3%) benefited from a medical follow-up by a nurse who visited once or twice a day. Compared to older adults living in nursing homes, those in foster families were more frequently women (61.7% vs 49.4%) and had lower ADL score (1.5 vs 2.4) and lower MMSE score (9.3 vs 11.3).</p><p><strong>Discussion and implications: </strong>The clinical profile of foster families' residents was quite similar to that of nursing home residents in terms of demographics, dementia, and dependency. Foster families might represent an interesting strategy to address the unmet clinical and social needs of dependent older adults, especially in countries where nursing homes are not sufficiently developed.</p><p><strong>Clinical trials registration number: </strong>NCT04545775.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 7","pages":"igae063"},"PeriodicalIF":4.9,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11290254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Kidney Disease Is Associated With Increased All-Cause Mortality Risk Among Older Black Adults.","authors":"Ryon J Cobb, Roland J Thorpe, Keith N Norris","doi":"10.1093/geroni/igae064","DOIUrl":"10.1093/geroni/igae064","url":null,"abstract":"<p><strong>Background and objectives: </strong>Older patients diagnosed with chronic kidney disease (CKD) have a higher risk of all-cause mortality than the general population. However, there is limited information available on how CKD relates to all-cause mortality among Black adults in the United States. We aimed to investigate how CKD relates to all-cause mortality risk among older Black adults.</p><p><strong>Research design and methods: </strong>This study draws on a subsample of self-identified Black participants (<i>N</i> = 1 393) from the Health and Retirement Study ages 52 to 96 who completed the anthropomorphic and biomarker supplement in 2006/2008. Our measure of CKD derives from serum cystatin C-based using dried blood spots, and all-cause mortality derives from the National Death Index and a key informant within the household from 2006 to 2019.</p><p><strong>Results: </strong>Twenty-nine percent of respondents died during the study period, whereas 31% had CKD. The mean age of the entire sample is 64.52. Results from our Cox proportional hazards models showed that CKD was independently associated with an increased risk of death from all causes among older Black participants in a model that adjusted for demographics, behavioral, clinical, and health characteristics.</p><p><strong>Discussion and implications: </strong>Results from our study confirm that CKD is associated with increased risk of death from all causes among older Black adults. Future studies should examine whether changes in CKD over time relate to all-cause mortality risk among older Black adults.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 1","pages":"igae064"},"PeriodicalIF":4.9,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11775827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Communication Matters: Loneliness in Senior Living Communities During the COVID-19 Pandemic.","authors":"Lindsay R Wilkinson, Julie L Masters, Julie Blaskewicz Boron","doi":"10.1093/geroni/igae060","DOIUrl":"10.1093/geroni/igae060","url":null,"abstract":"<p><strong>Background and objectives: </strong>The purpose of this study was to investigate individuals residing in senior living communities (SLCs) amid the coronavirus disease 2019 (COVID-19) pandemic. One reason those living in SLCs often choose these communities is to have a readily available social network. Necessary social distancing disrupted this socialization, thus, possibly increasing perceptions of loneliness in residents of SLCs. This study examined relationships among loneliness, perceived provider communication about the pandemic and related restrictions, as well as individual characteristics.</p><p><strong>Research design and methods: </strong>In December 2020, a survey was administered to older adults residing in a network of SLCs in Nebraska. Utilizing data from 657 residents aged 60 and older, ordinary least squares regression models were used to examine associations between 2 distinct measures of perceived provider communication and feelings of loneliness during the pandemic. The analysis also considered whether these associations varied as a function of education.</p><p><strong>Results: </strong>The respondents were, on average, 84 years of age, primarily female (72%), and living independently (87%) in the SLC. The linear regression results revealed that 53% of respondents were very lonely during the pandemic. However, provider communication that was rated as helpful to residents' understanding of the COVID-19 pandemic was associated with lower perceived loneliness. There was not a similar association for provider communication regarding services and amenities, and the association was not present for those with the highest level of education.</p><p><strong>Discussion and implications: </strong>Provider communication in times of disruption from normal activities, such as with the COVID-19 pandemic, is important to perceptions of loneliness among those living in SLCs, particularly for those with lower educational attainment. SLCs are communities that individuals select to reside in, and through communication, providers may have the opportunity to positively affect resident experiences, especially in times of stress.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 7","pages":"igae060"},"PeriodicalIF":4.9,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11258898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and Effectiveness of Physical Therapist-Supervised Exercise Interventions for Nursing Home Residents With Dementia: A Systematic Review.","authors":"Dennis Boer, Charlotte Schmidt, Shanty Sterke, Jan Schoones, Roy Elbers, Thea Vliet Vlieland","doi":"10.1093/geroni/igae061","DOIUrl":"10.1093/geroni/igae061","url":null,"abstract":"<p><strong>Background and objectives: </strong>Although physical therapy, in particular exercise therapy, is widely used in nursing home residents with dementia, the literature on this topic is relatively scarce. This systematic review aimed to summarize the literature on the characteristics and effectiveness of exercise interventions supervised by physical therapists in nursing home residents with dementia.</p><p><strong>Research design and methods: </strong>Six electronic databases were systematically searched for relevant studies up to August 17, 2022. Randomized controlled trials (RCTs) comparing exercise interventions supervised by a physical therapist to any other form of intervention or usual care in nursing home residents with dementia were selected. Data were narratively analyzed and forest plots visualizing exercise effects were created.</p><p><strong>Results: </strong>From the 1 377 records retrieved and screened, 6 RCTs, reported in 11 papers, met the selection criteria. Included studies used multimodal or aerobic exercise interventions, with the frequency, duration and intensity varying across studies. Three of the 6 studies were at high risk of bias. Due to inconsistency in the findings and variety in outcome measures, results on the effectiveness of the interventions are inconclusive.</p><p><strong>Discussion and implications: </strong>Our review emphasizes the need for more robust studies to offer understanding of the efficacy of exercise interventions supervised by physical therapists for nursing home residents with dementia.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 7","pages":"igae061"},"PeriodicalIF":4.9,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aging and Olfactory Training: A Scoping Review.","authors":"Megan Loughnane, Victoria Tischler, Reem Khalid Saifeldeen, Emily Kontaris","doi":"10.1093/geroni/igae044","DOIUrl":"10.1093/geroni/igae044","url":null,"abstract":"<p><strong>Background and objectives: </strong>Decreased olfactory function commonly occurs alongside the aging process. Research suggests olfactory training (OT) has the potential to improve olfactory and cognitive function in individuals with and without olfactory dysfunction. The degree to which these benefits extend into older age and among those with cognitive impairment (i.e., people with dementia and mild cognitive impairment) is less clear. The purpose of the current review was to investigate the extent to which OT affects olfactory function, cognition, and well-being among older people.</p><p><strong>Research design and methods: </strong>A scoping review of the literature was conducted in PubMed, Embase, EbscoHost, and SCOPUS. Articles were considered eligible for original research studies with human populations, included adults aged 55 and older, performed any type of OT, and included a form of olfactory testing. The data from the included studies were synthesized and presented narratively.</p><p><strong>Results: </strong>A total of 23 studies were included. The results suggest that OT provides multiple benefits to older adults, including those with cognitive impairment. Particularly, OT was associated with measurable changes in olfactory function, improved cognitive function, specifically semantic verbal fluency and working memory, reduced depressive symptoms, and protection from cognitive decline.</p><p><strong>Discussion and implications: </strong>The findings suggest that benefits from OT extend beyond changes in olfactory function and include improved cognitive function, amelioration of depressive symptoms, and protection from cognitive decline. Future research is needed across specific participant groups, including those with differentiated types of dementia, to investigate the olfactory and cognitive benefits of OT.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 6","pages":"igae044"},"PeriodicalIF":4.9,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11176978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Dual-Language Touch-Screen Intervention to Slow Down Cognitive Decline in Older Adults: A Randomized Controlled Trial.","authors":"Wei Quin Yow, Ka Lon Sou, Alina Clarise Wong","doi":"10.1093/geroni/igae052","DOIUrl":"10.1093/geroni/igae052","url":null,"abstract":"<p><strong>Background and objectives: </strong>Bilingualism has been suggested to protect older adults from cognitive aging and delay the onset of dementia. However, no studies have systematically explored bilingual usage as a tool to mitigate age-related cognitive decline. We developed the Dual-Language Intervention in Semantic memory-Computerized (DISC), a novel cognitive training program with three training tasks (object categorization, verbal fluency, and utility of things) designed specifically for older adults that featured two modes: single-language (SL) exposure mode and dual-language (DL) exposure mode.</p><p><strong>Research design and methods: </strong>The final sample included 50 cognitively healthy (CH; 33 female, <i>M</i> _age = 72.93 years, range = 53.08-87.43 years) and 48 cognitively impaired (CI; 35 female, <i>M</i> _age = 80.93 years, range = 62.31-96.67 years) older adults, randomly assigned them into one of three groups: SL group, DL group, and control group (no training). Participants in SL and DL groups used DISC in either SL mode (i.e., training instructions were spoken in only one language throughout the entire training) or DL mode (i.e., training instructions alternated between two languages), respectively, for 24 sessions. Participants in the control group were asked to continue with their normal daily activities (e.g., playing bingo and reading newspapers).</p><p><strong>Results: </strong>For CH older adults, we found significant improvements in the Rey Auditory Verbal Learning Test (RAVLT) Trial 5 score and the Clock Drawing Test score in the DL group but not in the SL and control groups posttraining compared with pretraining. For CI older adults, there was a delayed improvement in the RAVLT Trial 1, six months later.</p><p><strong>Discussion and implications: </strong>Our findings provided novel evidence that implementing DL cognitive training benefits CH older adult's late verbal learning and visuospatial construction skills, and a delayed improvement in CI older adults' early verbal learning abilities.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 7","pages":"igae052"},"PeriodicalIF":4.9,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Factors Associated With Longitudinal Patterns of Hearing Aid Use.","authors":"","doi":"10.1093/geroni/igae045","DOIUrl":"https://doi.org/10.1093/geroni/igae045","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/geroni/igae011.].</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"8 5","pages":"igae045"},"PeriodicalIF":7.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141079986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}