Innovation in Aging最新文献

{"title":"The life course impact of adverse childhood experiences on chronic pulmonary disease: the roles of inflammatory response and social buffering.","authors":"Hui Xu, Rongrong Yang, Min Zhu, Kaiwang Cui, Jianping Liu, Xiangwen Gong","doi":"10.1093/geroni/igag008","DOIUrl":"10.1093/geroni/igag008","url":null,"abstract":"<p><strong>Background and objectives: </strong>Identifying modifiable risk factors for chronic lung diseases (CLDs) is crucial for promoting healthy aging, preventing disease progression, and improving the quality of life for affected individuals. We aimed to assess the association between 2 types of adverse childhood experiences (ACEs) and CLDs, considering inflammation and childhood friendships.</p><p><strong>Research design and methods: </strong>Data come from the China Health and Retirement Longitudinal Study (<i>n </i>= 12 542, aged ≥45 years), with data on ACEs, high-sensitivity C-reactive protein (hs-CRP), childhood friendship, and CLDs collected at baseline. Logistic regression was used to examine the associations between ACEs, childhood friendship, and CLDs. Generalized structural equation modeling was conducted to assess the mediating effects of hs-CRP on the ACE-CLD associations.</p><p><strong>Results: </strong>Compared to no threat-related ACEs, exposure to 1 (OR = 1.16) or ≥2 (OR = 1.47) threat-related ACEs was associated with increased odds of CLDs; exposure to 1 (OR = 1.47) or ≥2 (OR = 1.53) deprivation-related ACEs was also associated with increased odds of CLDs. Hs-CRP could account for 3.0% of the threat-related ACE-CLD association. Among participants with deprivation-related ACEs, compared to 0 points for childhood friendship, 1, 2, and 3 points could decrease 19% (0.81; 0.58, 1.12), 22% (0.78; 0.57, 1.07), and 45% (0.55; 0.40, 0.77) in CLDs, respectively. The additive and multiplicative interaction between childhood friendship and deprivation-related ACEs on CLDs was statistically significant.</p><p><strong>Discussion and implications: </strong>Both threat-related and deprivation-related ACEs were associated with the increased odds of CLDs. Hs-CRP could partially mediate the relationship between threat-related ACEs and CLDs. Good childhood friendships could mitigate the risk of CLDs related to deprivation-related ACEs.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 5","pages":"igag008"},"PeriodicalIF":6.2,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13074434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147689975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A national pilot study to inform the design of a Longitudinal Interdisciplinary National Data on Ageing for Australia (LINDA).","authors":"Mitiku Teshome Hambisa, Kim M Kiely, Ranmalee Eramudogolla, Natasha Ginnivan, Meiwei Li, Rebecca Ivers, John Piggott, Edgar Liu, Kenneth M Langa, Dan Dumbrell, Kaarin J Anstey","doi":"10.1093/geroni/igaf149","DOIUrl":"10.1093/geroni/igaf149","url":null,"abstract":"<p><strong>Background and objectives: </strong>To better inform service provision and social services, Australia has long needed a comprehensive national ageing study that is comparable with international ageing studies and eligible to join the register of harmonized cross-national studies of ageing. We conducted a pilot study to fill this gap in Australia's social and health data collection on ageing.</p><p><strong>Research design and methods: </strong>We utilized online computer-assisted web interviewing (CAWI) and a follow-up Telephone Interview for Cognitive Status (TICS) screening. Participants were drawn from a Roy Morgan Consumer Panel using random probability sampling. Data collected were compared with the national Census data.</p><p><strong>Results: </strong>Among 1172 online CAWI survey participants (mean age: 65.8 years; 51.0% female), 46.8% had a chronic health condition or disability, 26.1% were full-time employed, and 46.8% were fully or partially retired. Compared with 2021 Australian Census data, the sample was broadly representative by age, sex, geographic region, and health, but respondents tended to have higher education levels (66% reported completing secondary schooling vs 42% in the Census) and underrepresented culturally and linguistically diverse backgrounds (21% born overseas vs 39%; 4% speak a language other than English at home vs 23%); 804 respondents completed TICS (mean[SD] = 33.6[2.8]; range: 22-41), with 71.4% classified as cognitively normal, 27.7% ambiguous, and 1.1% cognitively impaired.</p><p><strong>Discussion and implications: </strong>This pilot demonstrated the feasibility of online and telephone-based data collection with cognitive screening to capture demographic and health profiles of older Australians, providing a strong foundation for future large-scale national ageing studies.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 3","pages":"igaf149"},"PeriodicalIF":6.2,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12924878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of civil money penalties on the financial performance of nursing homes.","authors":"Patrick Schumacher","doi":"10.1093/geroni/igag002","DOIUrl":"10.1093/geroni/igag002","url":null,"abstract":"<p><strong>Background and objectives: </strong>Civil money penalties (CMPs) are an important tool for holding nursing homes accountable for regulatory noncompliance. These fines can range from a few thousand to hundreds of thousands of dollars. Meanwhile, many nursing homes operate under financial strain, which has been linked to compromised quality of care. This study assesses the impact of CMPs on 2 indicators of financial performance: net income margin and short-term debt.</p><p><strong>Research design and methods: </strong>These indicators were regressed on penalty size using a 2-way fixed effects model, encompassing 87,249 facility-year observations from U.S. nursing homes from 2012 to 2019. The dollar amount of penalties was expressed in equivalent days of operating expenses to account for variation in facility sizes, and the analysis controlled for the nursing home characteristics and market conditions.</p><p><strong>Results: </strong>A negative relationship was found between the size of penalties and net income margin. Penalties equivalent to less than 1 day of expenses were associated with a 0.86 percentage-point decrease in net-income margin; 1-day penalties with a 1.48-point decline; 2-day penalties with a 2.49-point reduction; and those equivalent to 3+ days corresponded to a 3.56-point decline. Effects on short-term debt were minimal, with only modest increases seen.</p><p><strong>Discussion and implications: </strong>These findings raise a concern for regulators that CMPs, if not carefully calibrated, have the potential to cross the boundary from deterring violations to jeopardizing the financial stability of nursing homes. If a facility struggles to absorb the cost, a CMP could inadvertently affect the care provided to residents.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 3","pages":"igag002"},"PeriodicalIF":6.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12924879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multilevel risk factors for financial fraud in later life: evidence from China.","authors":"Ting Hu, Flavia Cristina Drumond Andrade, Yu-Chih Chen","doi":"10.1093/geroni/igag004","DOIUrl":"10.1093/geroni/igag004","url":null,"abstract":"<p><strong>Background and objectives: </strong>Older adults are particularly vulnerable to financial fraud. However, research on risk factors for later-life fraud has focused more on individual attributes than contextual factors and has not examined diverse types and amounts of financial loss when measuring financial fraud. We address these gaps using a comprehensive framework to explore the multilevel risk factors for fraud in later life.</p><p><strong>Research design and methods: </strong>Using data from the 2015-2018 China Health and Retirement Longitudinal Study (<i>n </i>= 10,010), we employed mixed-effects models to examine three outcomes: fraud exposure, type of victimization, and the amount of financial loss. We analyzed three key elements of routine activity theory: target characteristics (e.g., prior fraud experience, socioeconomic status, cognition), guardianship (e.g., marital status, social participation), and motivated offenders (e.g., local context, available financial institutions, GDP).</p><p><strong>Results: </strong>Prior fraud experience was associated with all three measures. Better episodic memory and greater social activity were associated with higher fraud exposure, while greater social activity was linked to lower financial loss. Additionally, contextual vulnerabilities (e.g., urban areas and more developed regions) were associated with increased exposure to fraud and financial loss.</p><p><strong>Discussion and implications: </strong>Our findings highlight the need for concerted action across all domains of multilevel factors to reduce fraud exposure, victimization, and financial loss among older adults. Program and policy efforts related to individual-level education, community-based guardianship (e.g., anti-scam hotlines and psychological support), and macro-level policies for monitoring and regulating financial environments should be established to combat financial fraud in later life.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 4","pages":"igag004"},"PeriodicalIF":6.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13039307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147609077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of digital reverse mentoring on older adults' digital literacy: mediating roles of self-perceptions of aging and self-efficacy.","authors":"Jierong Hu, Minzhi Ye, Haotian Wan, WengIan Leong","doi":"10.1093/geroni/igag001","DOIUrl":"10.1093/geroni/igag001","url":null,"abstract":"<p><strong>Background and objectives: </strong>Digital literacy is critical for older adults to maintain social connections, access information, and support overall mental well-being. However, many older adults struggle with using digital devices. Guided by the self-fulfilling prophecy theory, this study investigates how digital reverse mentoring (DRM), referring to younger individuals assisting older adults in learning and using digital technology, is associated with digital literacy, with self-perceptions of aging and self-efficacy as mediators.</p><p><strong>Research design and methods: </strong>A cross-sectional study was conducted with 402 community-dwelling older adults aged 60+ in Macao, China. Control variables include gender, age, education, income, self-rated health, and home internet access. Structural equation modeling was employed to test hypothesized relationships and mediation effects.</p><p><strong>Results: </strong>DRM significantly improved digital literacy (<i>B</i> = .31, 95% CI: .19, .43). Positive perceptions of aging were positively associated with digital literacy (<i>B</i> = .05, <i>p</i> < .001), whereas negative perceptions showed a negative association (<i>B</i> = .09, <i>p</i> < .001). Contrary to expectations, self-efficacy did not show a significant association with digital literacy. Indirect effects revealed that DRM was positively associated with all mediators (<i>B</i> = .12, 95% CI: .04, .20), suggesting that improving perceptions of aging through DRM may enhance digital literacy.</p><p><strong>Discussion and implication: </strong>This study highlights the importance of DRM educational interventions in boosting digital literacy among older adults by positively shaping their perceptions of aging. Addressing these perceptions can break down barriers and promote more inclusive digital participation. Future research should investigate the longitudinal effects and effective intervention strategies to enhance digital literacy.</p><p><strong>Innovation and translational significance: </strong>This study addresses the age-related digital divide by examining DRM as a strategy to improve digital literacy among older adults. Using a psychological framework, we identify perceived aging as a key mediator, showing that increased positive perceptions of aging and reduced negative perceptions of aging enhance digital outcomes. Findings suggest that DRM, as an empowering approach, can be effectively integrated into social service programs and policies to promote digital inclusion and reduce the age-related digital divide. This work offers a practical and evidence-based model for improving individual and societal outcomes in later life through intergenerational engagement.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 3","pages":"igag001"},"PeriodicalIF":6.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12915416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Financial capability and economic well-being of older Americans: empirical insights from the financial capability framework.","authors":"Yu-Chih Chen, Sicong Sun, Jin Huang, Margaret S Sherraden","doi":"10.1093/geroni/igag003","DOIUrl":"10.1093/geroni/igag003","url":null,"abstract":"<p><strong>Background and objectives: </strong>Financial capability, the interaction of financial literacy, access, and behavior, can influence individuals' ability to manage finances and build economic stability over the life course. However, empirical evidence linking financial capability and economic well-being in old age is limited. We examine the components and mechanisms of the financial capability framework and investigate the differences between middle-aged (aged 50-64) and older adults (aged 65+) using population-based data in the United States.</p><p><strong>Research design and methods: </strong>The respondents, 12,840 individuals aged 50 and over, were selected from the population-based 2018 National Financial Capability Study. Structural equation modeling and multigroup analyses were used to examine the mechanisms of financial capability on economic well-being and the moderating effects of age.</p><p><strong>Results: </strong>Financial literacy and access are positively associated with financial behavior and subsequent economic well-being. The mediation results show that financial literacy and access are equally important in contributing to economic well-being in later life. However, age has no moderating effect, suggesting these associations operate similarly in middle-aged and older adults.</p><p><strong>Discussion and implications: </strong>Strategies to promote economic well-being in later life through effective finance should be multifaceted, targeting each aspect of financial capability. Financial practices such as financial coaching and guidance, credit counseling, and financial assessments should be integrated into social services. Policy innovations that expand financial inclusion, particularly investments in accessible and appropriate financial products, should be developed to reach and cover the financially underserved, especially those with limited financial literacy and restricted access to mainstream financial services.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 4","pages":"igag003"},"PeriodicalIF":6.2,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13031003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147573925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and acceptability of 7-day smartphone-based, activity-triggered Ecological Momentary Assessment among low-income older adults.","authors":"Olivia S Malkowski, Genevieve F Dunton, Nick P Townsend, Mark J Kelson, Max J Western","doi":"10.1093/geroni/igaf151","DOIUrl":"10.1093/geroni/igaf151","url":null,"abstract":"<p><strong>Background and objectives: </strong>Smartphone-based Ecological Momentary Assessment (EMA) is increasingly used to collect real-time data on physical activity behavior. However, no activity-triggered EMA studies have been conducted among low-income older adults. We aim to assess the feasibility and acceptability of activity-triggered EMA in low-income older adults.</p><p><strong>Research design and methods: </strong>Researchers partnered with community organizations and provided technical support to facilitate the recruitment and retention of low-income older adults. For 7 days, 39 older adults (76.4 ± 8.5 years; 76% earning below £25 000/year) received EMA surveys when they surpassed a predefined activity/inactivity threshold, or when two hours elapsed between prompts. Participants wore a Move 4 activity sensor to measure their steps. A post-study questionnaire assessed perceptions of acceptability.</p><p><strong>Results: </strong>Participants completed 84% of the EMA surveys they received. EMA compliance did not appear to differ as a function of age, biological sex, time of day, day of week, or concurrent physical activity. Responses to the post-study questionnaire revealed that the most enjoyable aspects of participating in the study were making a worthwhile contribution to science and becoming more self-aware of their feelings and/or activities. The least enjoyable aspects included the frequency or timing of EMA prompts, the interruption of activities to complete an EMA survey, and limited or inadequate response options for certain EMA items.</p><p><strong>Discussion and implications: </strong>Smartphone-based, activity-triggered EMA is feasible and acceptable among low-income older adults. Fostering community partnerships, managing participant resource constraints, and providing technical support are crucial strategies for engaging and retaining this population in mobile health research.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"10 2","pages":"igaf151"},"PeriodicalIF":6.2,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12926715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147283736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Participant Index.","authors":"","doi":"10.1093/geroni/igaf122.4415","DOIUrl":"https://doi.org/10.1093/geroni/igaf122.4415","url":null,"abstract":"","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 Suppl 2","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12761514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Disability, Service Coordination, & Outcomes in Publicly-Funded Long-Term Services & Supports.","authors":"Romil Parikh, Dana Urbanski, Chanee Fabius, Stephanie Giordano, Eric Jutkowitz, Tetyana Shippee","doi":"10.1093/geroni/igaf122.013","DOIUrl":"https://doi.org/10.1093/geroni/igaf122.013","url":null,"abstract":"<p><p>People living with physical disability (PD) receiving long-term services & supports (LTSS) experience greater unmet service needs. It is unclear if having a case manager for service coordination modifies PD-associated LTSS outcomes. To fill this knowledge gap, we evaluated associations of PD with emergency department (ED) visits and community integration among older LTSS consumers with and without a case manager. Among 6,756 respondents (age, ≥65 years) from the National Core Indicators- Aging & Disability Survey (2018-2019), we evaluated three dichotomized outcomes (yes vs no): ED visits (over 12 months); and self-reported community integration indicated by both- activity (i.e. being as active in community as preferred) and enjoyment (i.e. enjoying things outside home). We used logistic regression, adjusting for consumers' sociodemographic and health-related characteristics, with random intercept for state. PD was documented in 60% of survey respondents. People living with PD were 27% more likely to report not having a case manager (p < 0.001). Among those without a case manager, PD was associated with significantly greater odds of ED visits (odds ratio [OR], 1.80, 95% CI, 1.48-2.19) and lower odds of community integration [activity: OR, 0.75, 95% CI, 0.62-0.90; enjoyment: OR, 0.69, 95% CI, 0.58-0.83]. These associations were attenuated among consumers with a case manager [ED visits: OR, 1.09, 95% CI, 0.94-1.25; activity: OR, 0.86, 95%CI, 0.75-1.00; enjoyment: OR, 0.85, 95% CI, 0.73-1.00]. Older LTSS consumers living with documented PD are more likely to report not having a case manager; and having a case manager might mitigate PD-associated adverse LTSS outcomes.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 Suppl 2","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12760035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145899598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced topic modeling with large language models: analyzing social media content from dementia caregivers.","authors":"Weiqing He, Bojian Hou, Amy Zheng, Yanbo Feng, Ari Klein, Karen O'Connor, Shu Yang, Tianqi Shang, George Demiris, Graciela Gonzalez-Hernandez, Li Shen","doi":"10.1093/geroni/igaf120","DOIUrl":"10.1093/geroni/igaf120","url":null,"abstract":"<p><strong>Background and objectives: </strong>While traditional topic modeling methods have been applied to analyze social media content from dementia caregivers, they often struggle with semantic understanding and coherent topic generation. This study explores the direct application of large language models (LLMs) for topic modeling of caregiver tweets, aiming to leverage their advanced semantic comprehension capabilities.</p><p><strong>Research design and methods: </strong>We analyzed 231 870 tweets from dementia caregivers after preprocessing using ChatGPT as the primary topic modeling tool. To address context length limitations, we developed a 2-stage approach: first splitting the dataset into 226 batches of 1000 tweets each for initial topic extraction, then combining these results through a second-stage prompt for final topic synthesis. We compared our approach against 11 baseline methods, including Latent Dirichlet Allocation (LDA), Gibbs Sampling Dirichlet Multinomial Mixture Model (GSDMM), their term-weighted variants, and state-of-the-art BERTopic models. Topic quality was evaluated using Sentence-BERT-based coherence scores, and topic comprehensiveness was assessed through both ChatGPT and human expert evaluation.</p><p><strong>Results: </strong>Our LLM-based approach achieved a coherence score of 0.358, significantly outperforming all baseline methods. Traditional approaches like GSDMM (0.317) and LDA (0.320), their term-weighted variants (ranging from 0.264 to 0.302), and BERTopic variants (approximately 0.30) showed lower coherence scores. The 2-stage batching strategy effectively handled the large dataset while maintaining topic quality and representativeness. Expert evaluation confirmed the topics' relevance to caregiver experiences and their comprehensive coverage of key themes.</p><p><strong>Discussion and implications: </strong>This study introduces a novel methodology for applying LLMs to large-scale topic modeling tasks, demonstrating superior performance over traditional and state-of-the-art approaches. The significant improvement in coherence scores suggests that LLMs can better capture the semantic relationships within topics. Our approach addresses key challenges in context length limitations and prompt engineering, while providing more coherent and interpretable insights into caregiver experiences that can inform targeted support strategies.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 Suppl 1","pages":"S38-S47"},"PeriodicalIF":4.3,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12742845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145850044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}